Nelson Albuquerque de Souza e SilvaFederal University of Rio de Janeiro | UFRJ · Instituto do Coração Edson Abdala Saad (ICEAS) e Faculdade de Medicina da UFRJ
Nelson Albuquerque de Souza e Silva
Professor Emérito (Emeritus Professor)
About
113
Publications
25,535
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Introduction
Grad.-Fac. de Med. (FM) da Univ. Federal do Rio de Janeiro-UFRJ (1965). Pós-grad: Resid. Int. Med.(1969-1971), Resid. Cardiov. Dis.(1971-1973), Senior Resid. Assoc. Cardiov. Dis.(1973) e Master of Sciences In Medicine (1974) - Mayo Graduate School of Medicine, Univ. of Minnesota-USA. Doutorado em Medicina (Cardiologia)-UFRJ (1981). Pós-doutorado em Epidemiologia Clínica (bolsista da OPAS) na Univ. de Mc Master (Canadá) -1984. Professor Titular da FM/UFRJ (1998). Prof. Emérito/ UFRJ (2014)
Additional affiliations
February 2006 - February 2010
March 2006 - present
Instituto do Coração Edson Saad da Universidade Federal do Rio de Janeiro
Position
- Managing Director
Description
- An specialized Institute for Cardiovascular Health Research of The Federal University of Rio de Janeiro
Education
July 1973 - December 1973
July 1971 - June 1973
July 1969 - June 1971
Publications
Publications (113)
Objective: To study the impact of the change in the
values of the Framingham equation base in the risk
prediction of 3 patients (low, medium and high risk).
Methods: Use of sensitivity analysis to study the
impact of this phenomenon on the change of the values
of the Framinghan equation base in the risk prediction
of 3 hypothetical patients (low, m...
A poluição do ar é um importante fator de risco a saúde associando-se a morbimortalidade e demonstrando relação inversa com as condições socioeconômicas. O objetivo do estudo foi descrever a variabilidade da qualidade do ar por Material Particulado (MP), e analisar a sua relação com o índice de Progresso Social (IPS), em 22 bairros do Rio de Janeir...
The prognostic value of atrial thrombi (AT) among elective patients with atrial fibrillation (AF) referred for a rhythm control strategy is unclear. In this study, clinical variables were correlated with the presence of AT and long term survival among 205 patients submitted to transesophageal echocardiography before elective AF cardioversion or abl...
Background:
Percutaneous coronary intervention (PCI) is the most frequently used invasive therapy for ischemic heart disease (IHD). Studies able to provide information about PCI's effectiveness should be conducted in a population of real-world patients.
Objectives:
To assess the survival rate of IHD patients treated with PCI in the state of Rio...
Background:
Diseases of the circulatory system are the leading cause of death in Brazil and the world, falling progressively during the twentieth century, preceded by an increase in Gross Domestic Product.
Objective:
To correlate balanced and adjusted mortality rates from circulatory system diseases in the municipalities of Rio de Janeiro state be...
Background:
Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survival.
Methods:
This was a retrospective study of 78,806 patients who underwent heart valve surgery between 2001 and 2007 in Bra...
Objective:
Complications after percutaneous coronary interventions (PCI) are associated with significant morbidity and mortality, although institutional discrepancies can occur when public and private hospitals coexist within the healthcare system. The aim of this study was to compare the in-hospital complication rates and mortality in addition to...
Background
Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS).
Objective
To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables....
Background/purpose:
Although troponin I (TnI) elevation and myocardial injury after percutaneous coronary interventions (PCI) are frequent findings, their prognoses remain controversial. We aimed to determine the association between any or ≥5 times TnI elevation after elective PCI and subsequent one year mortality rates and long term survival.
Me...
The authors discuss the high occurence of Troponin I elevation after elective percutaneous coronary intervention and its association to death up to one year after the procedure. They conclude that clinicians must take this fact under consideration when indicating a procedure which is performed to prevent cardiac death or myocardial infarction and i...
Background: Ischemic heart diseases (IHD) are important causes of deaths in the state of Rio de Janeiro (RJ). Coronary artery bypass grafting (CABG) and coronary angioplasty (CA) procedures aim to mitigate the effects of IHD. Awareness of the efficiency of these procedures is crucial for clinical and administrative decision making.
Objective: To de...
Troponin elevation after coronary angioplasty is a prognostic marker associated with significant morbidity and mortality, although its prevalence varies according to clinical and procedural characteristics. We analyzed the frequency of post-procedural enzyme elevation among 112 elective interventions between 2013 and 2014 in a private hospital in B...
Abstract
Background: Diseases of the circulatory system (DCS) are the major cause of death in Brazil and worldwide.
Objective: To correlate the compensated and adjusted mortality rates due to DCS in the Rio de Janeiro State municipalities between 1979 and 2010 with the Human Development Index (HDI) from 1970 onwards.
Methods: Population and death d...
Despite medical advances, mortality due to acute coronary syndrome remains high. For this reason, it is important to identify the most critical factors for predicting the risk of death in patients hospitalized with this disease. To improve medical decisions, it is also helpful to construct models that enable us to represent how the main driving fac...
Resumo
Objetivos: A causa básica de morte é o diagnóstico único ao qual se atribui a causa da morte. Outros códigos de diag-nóstico anotados na declaração de óbito, são as causas múltiplas. O estudo das causas múltiplas permite identificar as doenças presentes no óbito. Objetivo: Conhecer as causas básica e múltiplas de morte após revascularização...
Introduction:
The underlying cause of death is the single diagnosis to which the cause of death is attributed. Other diagnostic codes written in the death certificate are the multiple causes. The study of the multiple causes allows the identification of the diseases present in the death.
Objective:
To analyze the underlying and multiple causes o...
Background: The outcomes of heart valve surgery (HVS) are unknown in middle-income countries.
Objectives: To analyze in-hospital and survival of HVS from 2001 to 2007 in Brazil.
Methods: This is a retrospective observational study of 78,806 patients. Two national databases were used, the Hospital Information System and the Mortality Information Sys...
HomeCirculationVol. 132, No. suppl_3Abstract 19733:
Long Term Outcomes of 78,808 Patients Undergoing Valve Heart Surgery in a Middle-income Country FREE ACCESSARTICLE Tools Share Jump to Abstract Footnotes INTERVENTION AND SURGERY SESSION TITLE: SURGICAL THERAPY FOR VALVULAR HEART DISEASE III Abstract 19733: Long Term Outcomes of 78,808 Patien...
Although there is strong evidence of the benefits of antihypertensive treatment, the high prevalence of this important cardiovascular risk factor and its complications, as well as the low control rates of hypertension observed in many studies justify the investigation of these relationships in population studies. The objective was to investigate th...
Method:
Were analysed in-hospital administrative database coming from the Public Health System of Rio de Janeiro (SUS-RJ) from 2006 through 2010 and the Public Registers of death of Rio de Janeiro (SIM-RJ) from 2006 through 2013. Both groups of information had linkaged using the Stata program of statistics. Three groups of age were studied: 50 yea...
Abstract Background: Circulatory system diseases (CSD) are the leading cause of death in Brazil.
Objective: To estimate CSD, cerebrovascular disease (CVD), and ischemic heart disease (IHD) mortality rates in adults in the municipalities of the state of Rio de Janeiro (SRJ), from 1979 to 2010.
Methods: The municipalities of SRJ were analyzed accordi...
Background:
Cardiac magnetic resonance imaging provides detailed anatomical information on infarction. However, few studies have investigated the association of these data with mortality after acute myocardial infarction.
Objective:
To study the association between data regarding infarct size and anatomy, as obtained from cardiac magnetic resonanc...
Hospital lethality following lower limbs revascularization in the State of Rio de Janeiro, Brasil, 2006/10
Introduction: Ischemic peripheral arteries disease is a form of presentation of systemic atherosclerosis and can be treated by angioplasty or open vascular surgery
Objective: To evaluate in-hospital lethality after lower limbs revascularizati...
Introduction:
Ischemic peripheral arterial disease is a form of presentation of systemic atherosclerosis and can be treated by angioplasty or open vascular surgery Objective: To find in-hospital lethality after revascularization according to sex, age, procedures and hospitalization conditions.
Method:
The data comes from authorizations to hospit...
Background:
End-stage kidney disease patients continue to have markedly increased cardiovascular disease morbidity and mortality. Analysis of genetic factors connected with the renin-angiotensin system that influences the survival of the patients with end-stage kidney disease supports the ongoing search for improved outcomes.
Objective:
To assess...
Purpose: Despite moderate decline of Cerebrovascular Disease (CBVD) in the last several decades, it is still the leading cause of death in the municipality of Rio de Janeiro (RJ). The spatial distribution of mortality across regions is unknown. The aim of this study was to understand the geographical distribution of deaths from CBVD in Rio de Janei...
Background:
Cardiovascular diseases are the major cause of death in Brazil.
Objective:
To correlate cardiovascular mortality rates in the states of Rio de Janeiro, São Paulo and Rio Grande do Sul, and in their capitals, between 1980 and 2008, with socioeconomic indicators collected from 1949 onwards.
Methods:
Population and death data were obt...
Resumo Fundamentos: A letalidade dos pacientes em hemodiálise (HD) é alta. Apenas os fatores de risco cardiovascular tradicionais não são capazes de explicar essa elevada taxa. Objetivo: Avaliar a sobrevida e sua associação com o polimorfismo dos genes do sistema renina-angiotensina (SRA): inserção/deleção da ECA e o M235T do angiotensinogênio em p...
Background:
The standardization of images used in Medicine in 1993 was performed using the DICOM (Digital Imaging and Communications in Medicine) standard. Several tests use this standard and it is increasingly necessary to design software applications capable of handling this type of image; however, these software applications are not usually fre...
In this work we present HeMoLab (Hemodynamics Modeling Laboratory), a computational environment for modeling the Human Cardiovascular System. Its integrates novel computational tools, running from medical image processing to numerical simulation and visualization. As a simulation tool, it allows to accommodate complex physiological and/or pathophys...
Abstract
Background: In Brazil, there are few appropriate records of acute coronary syndrome (ACS) with their in-hospital and post-discharge outcomes.
Objectives: To describe clinical characteristics, progress and lethality for ACS in-hospital and development within
three years after discharge.
Methods: Retrospective cohort study of adults with ACS...
Background: The angiotensin-converting enzyme (ACE) is an important blood pressure (BP) regulator, and ACE gene polymorphisms are associated with alterations in BP. No studies have yet been conducted on growth hormone (GH) replacement in adults with GH deficiency (GHD) according to ACE genotypes. Objective: To evaluate cardiovascular response to GH...
Abstract
Background: Studies in Brazil suggest that up to 60% of coronary angiographies (CA) are normal among patients in public health units (PHU).
Objective: To determine whether cardiology consults reduced the percentage of examinations without
obstructive coronary disease (OCD) among referred patients undergoing CA at a federal University Hospi...
Expenses with coronary artery bypass grafting (CABG) surgery and coronary angioplasty (CA) represented a significant cost to SUS.
To analyze SUS expenses with CABG and CA and their performance in hospitals in the state of Rio de Janeiro (SRJ), from 1999 to 2008.
The information came from paid HAA in hospitals with more than 100 revascularization pr...
OBJECTIVE: To evaluate associations between post-operative complications in patients who survive surgery and in-hospital deaths and lengths of hospital stays of patients who undergo coronary artery bypass graft surgery METHODS: Patients who underwent coronary artery bypass graft surgery and survived the operating theater were randomly selected. Inf...
Objective:
To evaluate associations between post-operative complications in patients who survive surgery and in-hospital deaths and lengths of hospital stays of patients who undergo coronary artery bypass graft surgery METHODS: Patients who underwent coronary artery bypass graft surgery and survived the operating theater were randomly selected. In...
The goal of this work is to gather recent advances in computational modelling aimed at tackling problems in the field of computational hemodynamics to provide insight about the flow regimes prevailing in certain vascular districts. These models are devised to retrieve the relevant physical phenomena from the different geometrical scales encountered...
Resumo Fundamento: Os gastos com cirurgia de revascularização do miocárdio (RVM) e angioplastia coronariana (AC), representaram importante ônus para o SUS. Objetivo: Analisar gastos do SUS com RVM e AC e sua performance nos hospitais do Estado do Rio de Janeiro (ERJ), de 1999 a 2008. Métodos: As informações provieram das AIH pagas dos hospitais com...
to evaluate mortality from all causes, diseases of the circulatory system (DCS), ischemic heart disease (IHD), and cerebrovascular diseases (CVD) from 1980 to 2006 in Rio de Janeiro, Rio Grande do Sul, São Paulo, and their capitals, taking into consideration the impact of deaths due to ill-defined causes.
population and mortality data were obtained...
BACKGROUND: Coronary artery bypass grafting
(CABG) is a consolidated procedure for the treatment of ischemic heart diseases
(IHDs), which requires continuous assessment.OBJECTIVE: To assess the quality of CABG surgery by reviewing patients'
clinical characteristics, mortality rates up to one year after hospital discharge,
primary causes of death an...
Coronary artery bypass grafting (CABG) is a consolidated procedure for the treatment of ischemic heart diseases (IHDs), which requires continuous assessment.
To assess the quality of CABG surgery by reviewing patients' clinical characteristics, mortality rates up to one year after hospital discharge, primary causes of death and postoperative compli...
FUNDAMENTOS: Modelos de estratificação de risco são utilizados em cirurgia para avaliar risco de morte. OBJETIVO: Fazer análise crítica da aplicação do EuroSCORE (ES) em amostras de prontuários de 2692 pacientes submetidos à cirurgia de revascularização miocárdica em 4 hospitais públicos do município do Rio de Janeiro, no período de 1999 a 2003. MÉ...
Risk stratification models are used to assess the risk of death in surgery.
To conduct a critical analysis of the EuroSCORE logistic model (ES) application in 2,692 patients undergoing Coronary Artery Bypass Grafting (CABG) in four public hospitals in the Rio de Janeiro Municipality, from 1999 through to December 2003.
Random samples of 150 medical...
To estimate in-hospital mortality and prevalence of complications of percutaneous transluminal coronary angioplasty (PTCA) in public hospitals.
Data for 2,913 PTCA were obtained from the Brazilian National Health System (SUS) Hospital Authorization Database in the city of Rio de Janeiro, Southeastern Brazil, between 1999 and 2003. After simple rand...
This article discusses communication in the physician-patient relationship with the aim of identifying potential instances of linguistic obstacles for the physician. The use of different linguistic variants and discursive strategies by the parties involved in communication are highlighted. The article shows that it is essential for physicians to be...
ABSTRACT
OBJECTIVE: To estimate in-hospital mortality and prevalence of complications of percutaneous transluminal coronary angioplasty (PTCA) in public hospitals. METHODS: Data for 2,913 PTCA were obtained from the Brazilian National Health System (SUS) Hospital Authorization Database in the city of Rio de Janeiro, Southeastern Brazil, between 199...
Background: Diseases of the circulatory system are the main causes of death in Brazil. Objective: To assess the evolution of mortality due to ischemic heart diseases (IHD), cerebrovascular diseases (CRVD) and ill defined causes (IDC) of death among adults in Rio de Janeiro State (RJS), Brazil, between 1980 and 2007. Methods: Population data from 19...
Our aim was to determine the frequencies of the angiotensin-converting enzyme (ACE) gene alleles D and I and any associations to cardiovascular risk factors in a population sample from Rio de Janeiro, Brazil. Eighty-four adults were selected consecutively during a 6-month period from a cohort subgroup of a previous large cross-sectional survey in R...
Background: There seem to be gender-based differences for surgical revascularization of the myocardium, with worse outcomes among women. Objective: To evaluate differences in the lethality rates for men and women and the percentage of deaths related to the circulatory system, diabetes mellitus and procedures (CSDMP) in-hospital and up to one year a...
OBJETIVO: Avaliar a prevalência de doença arterial coronariana (DAC) na valvopatia de etiologia reumática e não-reumática, examinando possíveis fatores preditivos da presença da doença. MÉTODOS: Estudo transversal, de série de casos obtidos em população pré-definida. Foram avaliados 1.412 pacientes com indicação de cirurgia cardíaca por qualquer et...
to estimate the prevalence of coronary artery disease (CAD) in valvular heart disease of rheumatic (RVHD) and non-rheumatic (NVHD) etiology, assessing possible predictive factors for the presence of CAD.
This is a cross-sectional study of a series of cases obtained from a pre-defined population, wherein 1,412 patients referred for heart surgery of...
Background: Cardiovascular diseases are the major cause of death in Brazil. Objective: To evaluate epidemiological and clinical characteristics, diagnostic and therapeutic procedures and in-hospital morbidity and mortality rates for patients with acute coronary syndromes (ACS) in the Niterói Municipality, Rio de Janeiro State, Brazil. Methods: 411...
Report on a case study of a female patient diagnosed with endomyocardial fibrosis and earlier episodes of supraventricular tachyarrhythmia that progressed through a decline in the function class (CF - NYHA), associated with junctional bradycardia.
This study analyzes hospital case fatality associated with percutaneous transluminal coronary angioplasties (PTCA) covered by the Brazilian Unified National Health System (SUS) and performed in hospitals in the State of Rio de Janeiro from 1999 to 2003. PTCA data were obtained from the State Health Department's database on Authorizations for Hospit...
O estudo analisa a letalidade hospitalar nas angioplastias coronárias, pagas pelo Sistema Único de Saúde (SUS), realizadas nos hospitais do Estado do Rio de Janeiro, Brasil, de 1999 até 2003. As informações sobre as angioplastias coronárias provieram do banco de Autorizações de Internações Hospitalares da Secretaria de Estado de Saúde do Estado do...
A Epidemiologia Clínica das Doenças Cardiovasculares Incapacitantes do Ponto de Vista Laborativo.
Epidemiology of Labor Incapacitating Cardiovascular Diseases.
Henrique Wolfgang Besser, Nelson Albuquerque de Souza e Silva, Gláucia Maria Moraes de Oliveira.
Universidade Federal do Rio de Janeiro, Secretaria de Administração e Reestruturação do Esta...
After an Acute Myocardial Infarction (AMI), the sooner the patient is approached, the greater are the chances that pharmacological therapy (using thrombolytics) be more effective than surgical intervention. Nevertheless, the thrombolytic therapy may have hazard effects on AMI patients that present any contraindication to it. As a consequence, param...
Fundamentos: Apesar de a seleção para o trabalho, as aposentadorias precoces e as dispensas estarem relacionadas a fatores de risco cardiovascular (FRCV), não se observa compromisso do governo, das empresas, das entidades patronais e dos trabalhadores para a prevenção e o tratamento destas condições no ambiente de trabalho. Objetivo: Estudar a aten...
To evaluate and compare adult mortality from diseases of the circulatory system (CDs), especially ischemic heart disease (IHD) and cerebrovascular disease (CVD), from 1980 through 2002 in the Brazilian states of Rio de Janeiro, Rio Grande do Sul, and São Paulo and their capital cities (respectively Rio de Janeiro, Porto Alegre, and São Paulo), taki...
To estimate the lethality rate of acute and chronic ischemic heart disease (IHD) procedures, coronary artery bypass graft (CABG) procedures and percutaneous transluminal coronary angioplasty (PTCA) procedures in the hospitals that are registered as service providers for the Hospital Information System/Single Healthcare System (SIH/SUS) plan in the...
Objetivo. Avaliar e comparar a mortalidade de adultos por doenças do aparelho circulatório (DAC), especialmente doenças isquêmicas do coração (DIC) e doenças cerebrovasculares (DCBV), no período de 1980 a 2002 nos Estados do Rio de Janeiro, Rio Grande do Sul e São Paulo e em suas capitais, levando em consideração o impacto dos óbitos por causas mal...
OBJETIVO: Estimar a letalidade nos procedimentos de doenças isquêmicas do coração (DIC) aguda e crônica e por revascularização miocárdica (RVM) e angioplastia coronariana (AC) nos hospitais cadastrados no SIH/SUS (Sistema de Informações Hospitalares/Sistema Único de Saúde) no Estado do Rio de Janeiro (ERJ), de 1999 a 2003. MÉTODOS: Os procedimentos...
To compare trends in mortality rates from cardiovascular diseases (CVD), ischemic heart diseases (IHD) and cerebrovascular diseases (CBVD) in the States of Rio de Janeiro (RJ), São Paulo (SP) and Rio Grande do Sul (RS) and respective capitals from 1980 to 1999.
Data regarding CVD deaths were obtained from Datasus, and those regarding populations we...
Medicine traditionally unites the art of clinical judgment to scientific knowledge. However, from the mid-20th century on, the innumerable new technological advances added to the clinical practice have contributed to the improvement of patient care on one hand, but on the other hand, they may at times inflict damage to people and transform physicia...
In this editorial article the author discusses the clinical and epidemiological data that appoints to socio-economic factors as major determinants of the atherothrombotic cardiovascular diseases. The abusive use of high cost and low results´ technology to diagnose and treat these diseases is criticized based on available published data.
Emphasis of...
OBJETIVO: Determinar a prevalência de fatores de risco para doença cardiovascular em funcionários do Centro de Pesquisas da Petrobras. MÉTODOS: Em estudo descritivo transversal, foram avaliados clínica e laboratorialmente, de março de 2000 e fevereiro de 2001, empregados do Centro de Pesquisas da Petrobras, tendo sido excluídos os que não comparece...
To determine the prevalence of risk factors for cardiovascular diseases in employees of the research center at Petrobras.
In a cross-sectional study, employees of the research center at Petrobras were assessed clinically and by laboratory testing from March 2000 and February 2001. Those who did not attend the periodical annual medical examination o...
A Epistemologia (do grego episteme: conhecimento;
logos: teoria), teoria do conhecimento, é o ramo da
Filosofia ou a Disciplina que estuda a investigação
científica e seu produto, o conhecimento científico.
Pretendemos abordar neste artigo, a evolução do
conhecimento científico na Medicina, argumentando
em favor da indissociabilidade entre ciência,...