Neily Zakiyah

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Verified

Neily verified their affiliation via an institutional email.

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• PhD
• Assistant Professor at Padjadjaran University

Pre-eclampsia is a pregnancy complication affecting both mother and fetus. Although there is no proven effective method to prevent pre-eclampsia, early identification of women at risk of pre-eclampsia could enhance appropriate application of antenatal care, management and treatment. Very little is known about the cost effectiveness of these and oth...

Background A significant number of women in low and middle income countries (L-MICs) who need any family planning, experience a lack in access to modern effective methods. This study was conducted to review potential cost effectiveness of scaling up family planning interventions in these regions from the published literatures and assess their impli...

Background: Prior studies reported that exposure to antidepressants during pregnancy may be associated with gestational hypertension. The aim of this study is to assess the association between the use of antidepressants during pregnancy and the risk of developing gestational hypertension. Methods: A retrospective cohort study using the prescript...

Objectives The aim was to estimate the long-term cost-effectiveness of improved family planning interventions to reduce the unmet need in low- and middle-income countries, with Indonesia and Uganda as reference cases. Methods The analysis was performed using a Markov decision analytic model, where current situation and several scenarios to reduce t...

Objective: Ulipristal acetate has been found to be non-inferior to other pre-operative treatments of uterine fibroids, particularly leuprolide. The objective of this study was to assess the pharmacoeconomic profile of ulipristal acetate compared to leuprolide for the pre-operative treatment of moderate to severe uterine fibroids in women of reprod...

Medication adherence among heart failure (HF) patients in the Middle East remains a critical, under-explored issue. This systematic review examines medication adherence rates and their influencing factors in this region. A search of PubMed, Scopus, and Google Scholar identified 12 studies published between 2013 and 2023, revealing an average non-ad...

Background Nonadherence to medication is common during pregnancy, as pregnant women often have concerns about the safety of the medications they are taking. This study aimed to assess medication adherence levels among pregnant women for various medications and to identify factors associated with nonadherence. Methods We conducted an observational...

Background Although the underlying mechanism of the effect of oral contraceptives (OCs) on blood pressure (BP) remains unclear, previous research showed that OCs are associated with an increased risk of elevated BP. This study aims to analyze the association between OCs and the risk of prehypertension and hypertension in women of reproductive age i...

Introduction Multiple micronutrient deficiencies might increase the adverse outcome during pregnancy and after birth. Considering the WHO recommendations since 2016 and scientific evidence from previous studies that multiple-micronutrient supplementation (MMS) is more effective than iron folic acid (IFA) in improving pregnant women’s health, it is...

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely administered in all age groups due to their effectiveness in reducing fever, relieving pain, and reducing inflammation. However, they have also been identified as the second most common cause of drug-induced hypersensitivity reactions, after beta-lactam antibiotics. Adverse reactions to NSAI...

Hypertension and chronic kidney disease (CKD) are interconnected conditions that can significantly affect a person’s health-related quality of life (HRQoL). In low- and middle-income countries (LMICs), this disease burden is heightened due to limited health resources and socio-economic challenges. Based on the available literature, this narrative r...

Background Effective hypertension management requires medication adherence to prevent complications. However, adverse drug reactions (ADRs) can undermine adherence and negatively affect patients’ quality of life. Limited research has explored the association between ADRs, medication adherence, and health-related quality of life (HRQoL) in individua...

Background: Although the underlying mechanism of the effect of oral contraceptives (OCs) on blood pressure (BP) remains unclear, previous research showed that OCs are associated with an increased risk of elevated BP. This study aims to analyze the association between OCs and the risk of prehypertension and hypertension in women of reproductive age...

Background Medication-related harm, including adverse drug events (ADEs) and medication errors, represents a significant iatrogenic burden in clinical care. Digital health technology (DHT) interventions can significantly enhance medication safety outcomes. Although the clinical effectiveness of DHT for medication safety has been relatively well stu...

Kesehatan jiwa merupakan hak asasi manusia, yang tidak terpisahkan dari kesehatan dan kesejahteraan secara umum. Literasi mengenai kesehatan jiwa pada masyarakat khususnya depresi pada kaum ibu, memegang peranan penting dalam pencegahan dampak merugikan baik pada skala lokal maupun global. Kegiatan pengabdian kepada masyarakat (PPM) ini dilakukan u...

Background In Indonesia, the adoption of telepharmacy was propelled by the COVID-19 pandemic, prompting the need for a user-friendly application to support both the general population and pharmacists in accessing healthcare services. Therefore, this study aimed to evaluate usability and user feedback of a pioneering telepharmacy application known a...

Background: Digital health interventions (DHIs) have shown promising results in enhancing the management of heart failure (HF). Although health care interventions are increasingly being delivered digitally, with growing evidence on the potential cost-effectiveness of adopting them, there has been little effort to collate and synthesize the findings...

Various internal and external factors negatively affect the homeostatic balance of the individual at the whole-body level and cause a state of stress. Stress affects the state of comfort and causes changes in energy consumption mechanisms to combat its effects. Individuals may be immunocompromised, susceptible to pathogens. Stress biomarkers play a...

The World Health Organization (WHO) recommends dolutegravir (DTG), a human immunodeficiency virus (HIV) medicine, as the first- and second-line treatment for all populations because, when compared to an efavirenz (EFV) regimen, plus two nucleoside reverse transcriptase inhibitors (NRTIs) has demonstrated significant effectiveness in HIV suppression...

Purpose The outbreak of COVID-19 has led to a global pandemic with millions of cases and deaths. Many randomized controlled trials (RCTs) were conducted to establish effective therapies. However, the methodological quality of these trials is paramount, as it directly impacts the reliability of results. This systematic review and bibliometric analys...

Health interventions contribute to the production of greenhouse gas emissions. Thus, reducing carbon footprint is essential in supporting the UK National Health Service (NHS) pathway to net zero. This study explores the approach in which carbon footprint can be included when applying Health Technology Assessment (HTA) modelling using obesity interv...

BACKGROUND Background: Digital health interventions (DHIs) have shown promising results in enhancing the management of heart failure (HF). Although healthcare interventions are increasingly being delivered digitally with growing evidence on the potential cost-effectiveness of adopting them, there has been little effort to collate and to synthesise...

Background Digital health interventions (DHIs) have shown promising results in enhancing the management of heart failure (HF). Although health care interventions are increasingly being delivered digitally, with growing evidence on the potential cost-effectiveness of adopting them, there has been little effort to collate and synthesize the findings....

Purpose This study aims to systematically review the hepatic safety of febuxostat and allopurinol in adult gout patients. Methods We searched for information using the following databases: PubMed, Cochrane Library, and Scopus. The inclusion criteria were to review all randomized controlled trials (RCT) that compared allopurinol and febuxostat for...

Introduction The need to enhance the utilization of the private sector for immunization programs in Indonesia while maintaining the high quality of services provided is evident. This study aimed to rapidly assess immunization services at private healthcare facilities in Indonesia by using Bandung, the most densely populated city, as the reference c...

ABSTRAK Ashitaba (Angelica keiskei Koidzumi) atau yang sering disebut juga sebagai seledri Jepang adalah tanaman yang berasal dari pantai Pasifik Jepang dan akhir-akhir ini menjadi populer sebagai obat herbal di negara-negara Asia. Di Indonesia, tanaman ini bisa ditemukan antara lain di Trawas, Tawangmangu, Manoko, dan Lombok. Berbagai macam golong...

Abstrak Hipertensi merupakan salah satu penyakit penyerta yang sering terjadi pada pasien penyakit ginjal tahap akhir (PGTA) yang sedang melakukan hemodialisis (HD) dan continuous ambulatory peritoneal dialysis (CAPD). Penggunaan obat antihipertensi yang tepat pada pasien PGTA dengan komorbid hipertensi dapat meningkatkan pengelolaan hipertensi, me...

Human genetic analyses and epidemiological studies showed a potential association between several types of gene polymorphism and the development of coronary heart disease (CHD). Many studies on this pertinent topic need to be investigated further to reach an evidence-based conclusion. Therefore, in this current review, we describe several types of...

Background: Safe and effective vaccination is considered to be the most critical strategy to fight coronavirus disease 2019 (COVID-19), leading to individual and herd immunity protection. We aimed to systematically review the economic evaluation of COVID-19 vaccination globally. Methods: We performed a systematic search to identify relevant stud...

Introduction Cardiovascular disease (CVD) is the leading cause of death worldwide and is the number one mortality cause in Indonesia. The highest percentage of its prevalence occurs in the elderly population. This research aims to assess the determinants of CVDs in the elderly population in Indonesia based on the Indonesian Family Life Survey 5 (IF...

Changing learning patterns from senior high school student to college student status is difficult, and each individual's response varies, some of which cause stress. Factors that cause stress are internal and external, and external factors consist of physical, conflict, emotional, and behavioral conditions. In comparison, the external factors consi...

Background Preeclampsia causes substantial maternal and perinatal morbidity and mortality and significant societal economic impact. Effective screening would facilitate timely and appropriate prevention and management of preeclampsia. Objectives To develop an early cost-effectiveness analysis to assess both costs and health outcomes of a new scree...

Background: Hypertension in pregnancy causes significant maternal and fetal mortality and morbidity. A comprehensive assessment of the effectiveness of antihypertensive drugs for severe hypertension during pregnancy is needed to make informed decisions in clinical practice. This systematic review aimed to assess the efficacy and safety of antihype...

Resiko komplikasi dan perburukan luaran maternal dan fetal yang terjadi akibat hipertensi selama kehamilan dapat dicegah dengan pengendalian tekanan darah melalui terapi antihipertensi. Tujuan dari studi ini adalah untuk memberikan gambaran penggunaan obat antihipertensi berdasarkan efikasi dan keamanannya pada kasus hipertensi selama kehamilan. De...

Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel strain that causes acute respiratory illnesses known as coronavirus disease 2019 (COVID-19). Currently, there is limited information regarding the therapeutic management for this disease. Several studies have stated that antivirals drugs such as remdesivir, favip...

Objective Sacubitril/valsartan is a relatively new medication that is more effective than the usual enalapril for heart failure patients with reduced ejection fraction. Therefore, this study aims to determine the cost-effectiveness of sacubitril/valsartan compared to enalapril in Indonesia’s healthcare system. Methods In this study, a Markov decis...

Background Alternative tobacco and nicotine products such as electronic cigarettes (EC), smokeless tobacco, and nicotine replacement therapy (NRT) are currently being assessed as options in tobacco harm reduction due to their potential role in smoking reduction and smoking cessation. Objective To provide the current evidence on the effectiveness a...

Background Multidrug Resistant Tuberculosis (MDR-TB) remains a burden on the healthcare system and public health. Evidence on cost and cost-effectiveness of MDR-TB treatment option is necessary in order to provide evidence-based recommendation for policymakers. The main therapy for MDR-TB consists of a combination of at least five types of anti-tub...

Since 2014, Indonesia has initiated to implement a national health insurance system, which included both of short- (SARC) and long-acting reversible contraceptive (LARC) into the benefit package. The aim of this study was to analyze the cost-effectiveness of contraceptive use in Indonesia after the implementation of the national health insurance in...

As a country with the high number of deaths due to pneumococcal disease, Indonesia has not yet included pneumococcal vaccination into the routine program. This study aimed to analyse the cost-effectiveness and the budget impact of pneumococcal vaccination in Indonesia by developing an age-structured cohort model. In a comparison with no vaccination...

Background Decision making processes regarding new vaccine prioritizations are complex. The objective of this study was to prioritize the introduction of new vaccines in Indonesia. Methods A multi-criteria decision analysis (MCDA) was applied in this study. A preliminary data collection form was developed to collect country-specific data in relati...

As a part of mitigation strategies during a COVID-19 pandemic, the WHO currently recommends social distancing measures through school closures (SC) and work closures (WC) to control the infection spread and reduce the illness attack rate. Focusing on the use of administrative and secondary data, this study aimed to estimate the costs and effects of...

Background The annual gross domestic expenditure on research and development (GERD) per capita of Indonesia ($24) remains relatively lower than the annual GERD per capita of neighboring countries, such as Vietnam ($36), Singapore ($1804), Malaysia ($361), and Thailand ($111). Objective The aim of this study was to conduct a cost-effectiveness anal...

Background: Evidence on costs and health benefits of pneumococcal conjugate vaccine (PCV) for children in Asian countries is limited but growing. As a region with a considerably high burden of pneumococcal disease, it is prominent to have a comprehensive overview on the cost-effectiveness of implementing and adopting a PCV vaccination program. Meth...

Despite the fact that morbidity and mortality rates due to dengue infection in Indonesia are relatively high, a dengue vaccination has not yet been introduced. Next to vaccination, Wolbachia-infected mosquitoes and health education have been considered to be potential interventions to prevent dengue infection in Indonesia. This study was aimed to a...

As one of Gavi, the Vaccine Alliance (previously the Global Alliance for Vaccines and Immunization), graduating countries, Indonesia is still eligible to access Gavi price for PCV13, PCV10 A and B. This study aims to estimate the economic impact of switch from the existing product/presentation of PCV (single-dose of PCV13) to the new product/presen...

Family planning is one of the healthcare programs in Indonesia that is included in the National Health Insurance (NHI) system. The purpose of this study was to determine the cost-effectiveness analysis of hormonal and non-hormonal contraceptive use in Indonesia during 2014–2017. A quantitative study was applied in this study and data collection was...

Psychotropic drugs were one of the the most widely used drugs in adolescent patients with intellectual disability in Mental Hospital of West Java. Pharmacoeconomic study on this topic is important because budget for psychotropic drugs need is increased while the available budget is still limited. The objective of this study was to analyze the utili...

CHEERS checklist. (DOCX)

PRISMA checklist. (DOC)

Full search strategy. (DOCX)

Objectives: Family planning is one of the initial strategies to improve maternal health in low and middle-income countries (L-MICs), where unmet need can still be high. The aim of this study was to estimate the cost-effectiveness of improved access to family planning in L-MICs, with Indonesia and Uganda as reference cases. Methods: Our analysis was...

The online version of this article (doi:) contains supplementary material, which is available to authorized users.

Provide a comprehensive overview of the existing evidence on the health economics of screening, diagnosis, and treatment options in preeclampsia. A systematic literature search was undertaken using three electronic databases (MEDLINE, Embase, Cochrane) to identify all English language full papers published between 1994 and 2014 containing economic...

Objectives: Breast milk is considered to give protection against rotavirus infection since it contains anti-rotavirus maternal antibodies and other nonspecific inhibitors. Multilevel promotion of breastfeeding is a complex intervention that modifies behavioral determinants through multiple levels of health promotion. This intervention can prolong t...

The introduction of the rotavirus vaccine in Indonesia is currently in its infancy. Delay in its development might be caused by factors related to the perceived value of the vaccine, health system characteristics and policy considerations. Other factors, which may also interfere with optimizing the introduction, are financial barriers because Indon...