Neela Gayathri Ganesan

Neela Gayathri Ganesan
  • Ph.D
  • Professor (Assistant) at Dongguk University

Research area *Encapsulating bioactive agent in Nanoemulsion(NE) *Stability studies *Compatibility b/w biosurfactants

About

15
Publications
3,973
Reads
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139
Citations
Current institution
Dongguk University
Current position
  • Professor (Assistant)
Additional affiliations
November 2020 - present
Birla Institute of Technology and Science, Pilani - Goa Campus
Position
  • Senior Researcher
November 2018 - November 2020
Birla Institute of Technology and Science, Pilani - Goa Campus
Position
  • Fellow
May 2015 - June 2016
Indfrag Biosciences Private Limited
Position
  • Project Manager
Education
August 2016 - May 2018
Anna University, Chennai
Field of study
  • Chemical Engineering
June 2015 - May 2017
Alagappa University
Field of study
  • Educational Management
June 2011 - May 2015
Anna University, Chennai
Field of study
  • Chemical Engineering

Publications

Publications (15)
Article
Aqueous solutions of surfactants exhibit remarkable differences in their adsorption properties on metal surfaces. This study evaluates the adsorption of surfactant mixtures on zinc metal surfaces. The adsorption of single surfactants cocamidopropyl betaine (CAPB) and sodium dodecyl benzenesulfonate (SDBS) and their mixtures from aqueous solution at...
Article
Aqueous solutions of surfactants exhibit remarkable differences in their adsorption properties on metal surfaces. This study evaluates the adsorption of surfactant mixtures on zinc metal surfaces. The adsorption of single surfactants cocamidopropyl betaine (CAPB) and sodium dodecyl benzenesulfonate (SDBS) and their mixtures from aqueous solution at...
Article
Full-text available
Nanoemulsions are colloidal systems characterized by tiny droplet sizes with increased kinetic stability. Due to their exceptional properties, nanoemulsions find applications in cosmetics, drug delivery, and food industry. Nanoemulsions can encapsulate bioactive compounds and distribute them efficiently for specific purposes. In the current work, w...
Article
This study examines the structural compatibility of various combinations of structurally diverse biosurfactants, saponin, a biosurfactant (derived from plants), and rhamnolipid and surfactin, biosurfactants derived from microorganisms) in the formulation of stable oil-in-water (O/W) nanoemulsion using the high-energy ultrasonication technique, and...
Chapter
Plant diseases need to be controlled as they hamper the ecosystem by affecting the quality and availability of food, feed, crops, and fiber produced by plants and farmers worldwide. Different methods and approaches are unraveled to prevent and control plant diseases. In agricultural practice, fungal diseases are the most common crop-devastating dis...
Conference Paper
Bacillus lipopeptides are promising biosurfactants that find applications in various sectors like biotechnological, cosmetics and biopharma due to their outstanding functionality like high specificity, low toxicity, and high surface activity. Among the different Bacillus species, Bacillus subtilis is well known for producing a biosurfactant surfact...
Article
The ample interesting properties of lipopeptide biosurfactants- to name a few- hemolytic, antiviral, antifungal, and antibacterial properties are of significant interest to the research community. Surfactin, one of the most potent microbial surfactants, is a biosurfactant of the lipopeptide type with interesting physicochemical characteristics and...
Article
The current work aims to formulate a stable cosmetic nanoemulsion using nature-derived ingredients such as surfactin (a lipopeptide-type biosurfactant produced by Bacillus sp) as an emulsifier, plant-based essential oil as a bioactive ingredient, and coconut oil as the base oil using high-energy ultrasonication method. To accomplish a stable nanoem...
Article
Nanoemulsions are being increasingly utilized in the pharmaceutical, cosmetics, and food industries. They have gained special attention in the cosmetic sector owing to their smaller size and higher kinetic stability and their ability to improve the cutaneous penetration of active ingredients. In addition, they reduce transepidermal water loss, whic...
Article
The present study is an attempt to throw insight into the significance of the type of nitrogen sources and their uptake pattern on the kinetics of surfactin production by Bacillus subtilis MTCC 2415. Batch kinetics studies revealed that surfactin production was strongly influenced by nitrate ions than ammonium ions. A maximum surfactin concentratio...
Article
Consumers of face-care cosmetics have been continuously evolving and are more receptive to skin-care products that integrate both health and wellness. This subsequently prompted cosmetic manufacturers to renew their formulation approaches by allowing gradual replacement of synthetic ingredients with promising natural alternatives. Among various ava...

Questions

Question (1)
Question
Greetings esteemed researchers!
I am relatively new to the field and would greatly appreciate some guidance on a challenge I'm encountering in my research.
We're currently engaged in a process akin to cloning, involving Hifi assembly to create linear DNA. The workflow entails N core extension, N core amplification, gene amplification and purification, C frag amplification and purification, Hifi assembly, and final expression and purification.
While following a protocol initially designed for cloning, we've observed that the expression of one particular gene isn't meeting our expectations. Upon consultation, it was suggested that we optimize the Hifi assembly step. (https://www.neb.com/en/protocols/2014/11/26/nebuilder-hifi-dna-assembly-reaction-protocol)
However, given the unique nature of our experiment, I'm unsure where to begin in terms of adjusting the ratios.
Our fragments have varying concentrations, and the molar ratio used for assembly (insert:vector = 2:1) might not be optimal for our setup. Could anyone provide insights or advice on how to approach optimizing these ratios effectively?
Your expertise and assistance in navigating this challenge would be immensely valuable to our research efforts. Thank you in advance for your support and guidance.
Ps. As I'm relatively new to this field, I find it challenging to discern the fragments clearly or to grasp the insights that come with experience. any help is appreciated!

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