Necip Kutlu

• Manisa Celal Bayar University

A BSTRACT Objective Anesthetic agents, which are used in appropriate doses for the application of the experimental procedure in animals, relieve pain when applied in sufficient amounts as well as muscle relaxation. However, many anesthetics can alter the dynamics of neuromuscular systems. We aimed to compare the effects of two frequently used anes...

In this study, it is aimed to reveal differences between the cognitive skills of the brain such as reaction time, speed distance estimation, nonverbal intelligence between different grade billiards players with numerical data. Research population consisted of professional and amateur male billiards players between the ages of 18-35. Cognitive abili...

Background: The gut microbiota modulates nervous system function. In the literature, it has been shown that this modula-tion is used in many nervous system injuries through oxidative stress (OS) and apoptosis mechanisms. In this study, it was aimed to investigate the neuroprotective effects of probiotic (PB) treatment in a rat traumatic brain inju...

The aim of the present study was to investigate the relationship between hand preference and electrophysiological parameters in women menstrual cycle phases and men. Our study was conducted on 25 healthy, naturally cycling females and 30 healthy males between the ages of 18 and 25 who participated voluntarily. The female participants completed thre...

Objective: There is a two way relationship between the gut microbiota and the brain. Oxidative stress and inflammation have important role in this damage of traumatic brain (TB). Pathologic alterations of intestine enviroment cause more problem for treatment of brain damage. Probiotics (PB) may potential to reduce oxidative stress and gliosis. In t...

Background/aim: Pneumocardiography (PNCG) is the recording method of cardiac-induced tracheal air flow and pressure pulsations in the respiratory airways. PNCG signals reflect both the lung and heart actions and could be accurately recorded in spontaneously breathing anesthetized rats. Nonlinear analysis methods, including the Lyapunov exponent, c...

ABSTRACT: The aims of this study were to determine various morphometric measurements of auricle, to investigate asymmetry and its relation with handedness in both sexes. Main morphometric measurements of both auricles and hand preferences were determined on 200 male and 200 female healthy university students. All measurements of the auricles were l...

4 Intruduction Several studies have suggested that long-term exercise may have facilitating effects on general cognitive functions. Physical training has been proposed to attenuate age-related decline in cognitive performance [1-5]. Numerous studies investigating age-related changes in performance on some cognitive tasks showed that subjects who en...

We explored the relations among paw preference, cerebral asymmetry and asymmetrical disruption of blood-brain barrier (BBB) permeability in normal and ovariectomized female rats with known paw preference. A high dose of pentylenetetrazol was used to disrupt the BBB and induce acute hypertension. To determine the areas of macroscopic infarct, sample...

We re-studied the distribution of paw preference in male and female rats using a new food-reaching test. Paw preference was assessed using a modified new version of food reaching task in quadrupedal position. Of the total sample (N=165). Of 165 rats, 86 (52.12%) were right-handed, 72 (43.64%) were left-handed, and 7 (4.24%) were mixed-handed. Of th...

ABSTRACT: The auricles are the defining features of human face. The aim of this study was to determine various morphometric measurements of auricle, to investigate asymmetry and its relation with handedness in both sexes. The study group consisted of200 male and 200 female university students with no history of trauma or congenital anomalies.The de...

Objective: Relationships amongst Big Five personality traits and DRD4, DAT1 and 5-HT2A gene polymorphisms were investigated in 193 college students participating in risky and non-risky sports. Material and Methods: Personality traits were assessed by Five Factor Personality Inventory (FFPI) and gene polymorphisms were analyzed by polymerase chain r...

The effects of acute exercise on immune system and serum magnesium and iron have been investigated in recent years. However, data related to the comparisons of long-term physical training with different intensity and duration are limited. The association between long-term physical training and cellular (lymphocyte phenotyping) and humoral immune pa...

The aim of the study was to investigate the effect of regular exercise on maximum oxygen uptake capacity (VO2max), reaction time (RT), testosterone (T), growth hormone (GH), insulin-like growth factor-I (IGF-I) in athletes compared to sedentary controls. VO2max, RT, T, GH, and IGF-I levels were 31.2 +/- 6.2 ml/min/kg, 106.7 +/- 23.2 s, 8.3 +/- 1.3...

This study was planned and applied in 2 stages. Stage I was applied to determine the knowledge of nurses working in the internal medicine, surgery, obstetrics and gynecology, pediatrics, and other services in Celal Bayar University Hospital about using intravenous catheter and intravenous fluid treatment, and the symptoms and treatment procedure fo...

The asymmetrical breakdown of the blood-brain barrier (BBB) was studied in female rats. Paw preference was assessed by a food reaching test. Adrenaline-induced hypertension was used to destroy the BBB, which was evaluated using triphenyltetrazolium (TTC) staining of the brain slices just after giving adrenaline for 30 s. In normal rats, the whole b...

The aim of this study was to determine the effect of chronic exercise on immune functions. Eighteen postmenopausal women were included in the study: nine were undertaking chronic exercise (exercise group) and the other nine were sedentary (control group). The exercise group had been training for 7.2 h per week for 19.9 years. The subjects were chos...

The relationship between serum total testosterone (T) concentration and fluid intelligence (nonverbal, spatial) was studied in consistently right-handed men with successful (S) or unsuccessful educational levels (NS). Hand preference was assessed by the Edinburgh Handedness Inventory. Nonverbal intelligence was measured by Cattell's Culture Fair In...

The erythrocyte glutathione reductase (GSSG-R) activity with and without FAD supplementation (Act. A and Act. B, respectively) was studied in 24 undialyzed uremic patients and 25 healthy subjects. Mean erythrocyte GSSG-R activity from normal subjects was 5.39 ± 1.43 U/g Hb (the active form). After the addition of FAD to the hemolysates, this increa...

The sexual dimorphism in the linear measures of the corpus callosum was studied in adult cats. In absolute measures, males had significantly larger genu, isthmus, and splenium than females; the mean absolute lengths were not significantly different in males and females. There were significant positive linear correlations between callosal measures a...

Sexual dimorphism in body and brain weight was studied in cats. Paw preference was assessed by food reaching test. Sexual dimorphism in body weight related to paw preference. Males weighted more than females in total sample and non-right-handed (NRH) cats (no significant difference in right-handed group). NRH males weighted more than right-handed (...

Grasp reflex and its asymmetry was studied in relation to pH of the umbilical blood in human newborns, to examine whether the degree of acidity in fetal blood (birth stress) is associated with cerebral laterality. Low pH values were considered as an index for birth stress. Grasp-reflex strength was found to be directly related to pH in total sample...

Paw preference (food reaching) with regard to relative right-and left-brain weights was studied in adult cats. In the right-pawed (RH) male and female cats, the right-paw use increased and the left-paw use decreased with increasing asymmetry coefficient (AC) for the right- and left brain-weight. The right-paw use increased with increasing the right...

Interrelationships among the right- (R), left- (L) brain weights, R-L brain weight, and R + L brain weight were studied in adult cats. The raw brain weights and the brain weights relative to body weight (brain weight: body weight) were studied separately. The raw R-L brain weight showed no significant correlation with the raw R+L brain weight. The...

The effect of right- and left-brain lesions on pentobarbitone-chlorpromazine induced tremor-bursts was studied in guinea pigs. The left-brain transections did not affect these tremor bursts except post-thalamic sections, which caused a complete disappearance of extensor jerks with coinciding tremors at four legs. These tremor bursts simultaneously...

The contributions of right- and left-brain weights to the ratio of the left- to the right-brain weight (L/R) were studied in cats. Brain weight was expressed as the ratio of brain weight to body weight. The relative right- and left-brains in the right-pawed male cats were found to be heavier and more asymmetric (L/R < 0) than those in the left-pawe...

The height of the end point of the sylvian fissure (SF) was analyzed in the right and left brains of male and female adult cats. A corrected SF asymmetry coefficient (AC) was computed for each brain. An AC larger than zero (AC+) showed a rightward asymmetry, and an AC smaller than zero (AC-) a leftward asymmetry. In the total sample, ACs fit a norm...

Asymmetry in the height of the right (R) and left (L) Sylvian end points was studied in right- (RH) and left-pawed (LH) male and female cats. Sylvian height was described relatively to brain weight. An asymmetry coefficient (AC) was estimated (R - L/.5*R + L). There was no significant relationship between R + L Sylvian height and AC, in the total s...

The association between serum zinc (Zn) level and the degree of hand preference was studied in right-handed young adults. Hand preference was scored by the Waterloo Handedness Questionnaire. Serum Zn level was determined by the flow injection analysis-atomic absorption technique. Zinc was found to be positively linearly and significantly correlated...

The associations between right and left hand skills to cerebral motor lateralization were studied in right-handed subjects with (FS+) and without (FS-) familial sinistrality. Hand preference was assessed by Oldfield questionnaire and hand skill by the peg moving task. The mean peg moving times (PMTs) and their standard deviations (SDs) were calcula...

A Parkinsonian-like tremor can be induced by a combined application of chlorpromazine and pentobarbitone in cats. Interestingly enough, only cats with left-paw preference were found to have a predisposition to this drug-induced tremor. The cats with ambidexterity and right-preference in paw use did not show any visible tremorogenic action of these...

The lateralization of the grasp reflex was studied in male and female newborns. The mean grasp-reflex strength of the right hand was found to be higher than that of the left hand in males, but the difference was not significant. The mean grasp-reflex strength of the right hand was found to be significantly higher than that of the left hand in femal...

The relation of the degree of grasp-reflex asymmetry to the strength of right- and left-hand grasp-reflex strength and body weight was studied in human newborn. In the total sample (N = 103), the right minus left (R-L) reflex strength was found to be positively linearly related to the grasp-reflex strengths from the right and left hands in FS-subje...

The grasp reflex was studied in human newborn without familial sinistrality. Of 60 females, 26 (43.3%) were right-handed and 34 (56.7%) ambidextrous. Of 62 males, 20 (32.3%) were right-handed, 39 (62.9%) ambidextrous, and 3 (4.8%) left-handed. There was a nonsignificant preponderance of right-dominance in females and a significant preponderance of...

The strength of the grasp reflex from the right and left hands was estimated in male and female newborns within the second day after birth. In the total sample (N = 121), the mean strength of the grasp reflex from the right hand was found to be significantly higher than that from the left hand. There was a significant positive linear correlation be...

Grasp-reflex asymmetry was studied in human newborns with regard to familial sinistrality (FS). In the total sample, the following results were obtained. The mean grasp-reflex strength from the right hand was found to be significantly greater than that from the left hand in FS- subjects. There was no significant difference between these parameters...

It was discovered by serendipity that a combined application of chlorpromazine (3.5 mg/kg) and pentobarbitone (20.0 mg/kg) induced intermittent tremor-bursts in four extremities of guinea pigs. This tremor with a prominent extensor activity disappeared after spinalization, indicating a supraspinal process. Biperiden reduced the frequency and amplit...

We have recently reported that a combined application of chlorpromazine and pentobarbitone induced intermittently occurring tremor bursts in guinea pigs (Tan et al., in press). This was a chance discovery. It will be shown in the present work that chlorpromazine is not essential for this postural tremor; only pentobarbitone in low dosages produced...

The distribution of paw preference was studied in male and female cats. Paw preference was assessed by the food reaching test. Of the total sample (N = 109), 54 (49.5%) cats were found to be right-preferent, 44 (40.4%) left-preferent, and 11 (10.1%) ambidextrous. In females (N = 63), 34 cats (54.0%) were right-preferent, 23 (36.5%) left-preferent,...

The effects of testosterone on paw preference assessed by a food reaching test was studied in adult cats. It was found that tetosterone propionate injected intramuscularly reduced the degree of the right-paw preference in right-preferent female cats. The paw preference of the male cats and left-preferent female cats was not affected by this male se...

Paw preference assessed by a food-reaching test was studied in male and female cats. Of the total sample (N = 66), 34 (51.5%) were right-preferent, 24 (36.4%) left-preferent, and 8 (12.1%) ambilateral. In the total sample, there was evidence for an overall paw preference, general paw preference, right-, and left-paw preference. The distribution of...