Nayan K Patel

• Bachelor of Medicine and Bachelor of Surgery (MBBS)
• Managing Director at NovoBliss Research Pvt Ltd, AHmedabad, India

Androgenetic alopecia (AGA) is a prevalent and progressive hair disorder affecting both men and women. It is characterized by the miniaturization of hair follicles, reduced hair density, and alterations in scalp conditions. Accurate assessment of hair growth parameters is crucial for understanding the progression of AGA and evaluating the efficacy...

Introduction Alopecia and graying hair, common conditions influenced by aging, genetics, and environmental factors, often see limited success with traditional treatments. Rosemary extract, valued for its antioxidant and anti-inflammatory benefits, has gained attention for promoting hair growth and reducing graying. Redensyl™, a plant-based ingredie...

Dandruff, a common scalp disorder often linked to Malassezia overgrowth, is characterized by flaking, itching, and irritation due to inflammation and compromised scalp barrier function. Conventional treatments focus on antifungal, anti-inflammatory, and keratolytic approaches. ThriveCo Anti-Dandruff Pre-Shampoo Treatment, powered with Zenscalpin™️...

Introduction: Hyperpigmentation, commonly known as dark spots, occurs when certain areas of the skin appear darker than the surrounding skin due to an excess of melanin production. Melanin is the pigment responsible for skin color, and its overproduction can lead to aesthetically concerning dark patches, despite them being generally harmless. Dark...

Scalp dandruff, a prevalent dermatological condition marked by flaking and itching, affects a large segment of the population. Sun exposure, genetics, and dryness, along with winter conditions, indoor heating, and hard water, all contribute to moisture loss and scalp imbalance. This study aimed to evaluate the safety, efficacy, and tolerability of...

Acne is a common inflammatory condition characterized by comedones, papules, and pustules, often resulting from increased sebum production influenced by hormones such as insulin-like growth factor-1 and androgens. Factors like Cutibacterium acnes, medications, sun exposure, cosmetics, and genetics exacerbate acne. This study aims to assess the safe...

Background: Understanding the differential impacts of natural versus artificial UV exposure and validating a method to evaluate tanning prevention products are crucial for advancements in dermatological research and skincare. This study aimed to develop and validate a process for inducing skin tanning using natural sunlight and artificial UV-lamps,...

Background Collagen, a key protein in the body maintains hair, skin and bone health and its production tends to decrease in synthesis as humans age. The demand for vegan collagen‐builder has increased worldwide due to increased adaptability to vegan diet. Objective This clinical study was designed aim to evaluate the safety and efficacy of vegan c...

Background: Hair quality assessment is crucial for evaluating the efficacy of hair care products. This study aimed to develop and validate In-Vitro methods for assessing efficacy of the various hair parameters using specialized techniques. Nine hair tresses were used per evaluation parameter, each hair tress standardized in weight, Methods: length,...

Introduction Scalp dandruff is a common dermatological condition characterized by flaking and itching of the scalp, affecting a significant portion of the population. Effective assessment methods are crucial for evaluating treatment outcomes. This study aimed to establish the reliability and correlation of three assessment techniques: Adherent Scal...

Background: Gummies offer a novel supplement delivery method appealing to children. This study investigates the safety, efficacy, and organoleptic properties of three distinct gummies-Curcumin Gummies, Vitamin-B-complex Gummies, and Vitamin-C Gummies in paediatric health. Methods: A 30-day open-label, three-arm, parallel design study with 48 childr...

Hair loss, a common multifactorial condition affecting both genders, results from causes like extrinsic factors (pollution, sun, humidity, and temperature), nutritional variation, or intrinsic factors such as ageing, heredity, hormonal and medical conditions. Some of the damages caused by these factors can be effectively managed with multivitamins,...

Background: Numerous methods are available for assessing effectiveness of oral/dental care products in clinical studies. However, a persistent debate surrounds the preference for specific methodologies over others. Intra-and inter-examiner variability are major concerns in both instrumental and visual examinations, as they can significantly influen...

Background: Skin, our body's crucial barrier, faces threats and requires maintenance. Controlled skin damage induced by Sodium Lauryl Sulphate (SLS) and tape-stripping provide insights into wound creation processes. Parameters like skin hydration, topography and inflammation are vital indicators. This study validates methods for wound creation / da...

Hair loss, commonly associated with genetics, hormones, or health conditions, is prevalent. Dandruff, resulting in flaky scalp skin, is also widespread. Ayurvedic herbal remedies show potential for addressing these hair issues. This clinical trial assesses the efficacy and safety of an ayurvedic hair oil in healthy adults with hair loss (alopecia)....

Background: Sleep disorders afflict millions globally, affecting overall health. Insomnia, characterized by difficulty falling or staying asleep, is particularly prevalent. Conventional treatments often pose side effects, prompting exploration of alternative approaches.This study investigates the safety and effectiveness of a natural sleep suppleme...

Cosmetic products are topical preparations widely used for cleansing, beautifying, promoting attractiveness or altering the appearance of body without affecting its structure or functions. Researches have shown that the frequent use of several cosmetics is linked to formation of comedones and acne because these products typically contain ingredien...

Research Update on NovoBliss Research for Month of Nov 2023 - Medical Director’s Visit to Beauty World 2023, Middle East - NovoBliss Family's Festive Spirit - Published Article in PARIPEX - Indian Journal of Research - Integration of Vita Easyshade Advance 5: A State-of-the-Art Advancement in Technology for Dental Color Measurement - Commencing Re...

Background Hair serum is recommended therapy for the management of hair fall problems. People of all ages suffer from hair fall. Aim To evaluate safety and efficacy of hair growth promoting product in healthy adult subjects with hair fall complaints (Alopecia). Methods In this safety and efficacy clinical study, 32 healthy individuals (aged 18–45...

Bovine collagen is a protein found in the connective tissue, bones, cartilage, and hides of cows. Remarkably, the collagen derived from cows closely resembles the collagen found in our own bodies. Collagen is advantageous for managing osteoarthritis symptoms.The aim of the study was to evaluate the safety, tolerability, and effectiveness of continu...

Citation: Mishra M, Patel N, Pandya I,et al. Evaluating the dermal safety and skin compatibility of personal care cosmetic products formulated with natural ingredients: An in-vivo primary irritation patch test study. Dermatol Res Skin Care. 2023;7(6):176 Background: Cosmetic products have been widely used by the public for an extended period, empha...

Hair graying is a common sign of aging resulting from complex regulation of melanogenesis. It occurs due to many factors, including age, oxidative stress, psychological stress, and malnutrition. Assessment of safety and effectiveness of an anti-gray hair product when applied to healthy adult human subjects having partially gray hair. Total 32 subje...

Collagen is abundant, forming 70-80% of skin's dry weight in mammals. Studies highlight improved skin, hair, and nail conditions post collagen treatment. We aimed to assess the safety, tolerability and effectiveness of AQUACOL™️ , a marine collagen derived from fish skin by proprietary process (enzyme hydrolysis), across various dosages (2.5g, 5g a...

Background: Multi-centered, multi-visit outpatient dermatology studies provide participant-friendly convenience, drawing diverse volunteers while avoiding extended facility stays. However, maintaining a consistent dermatologist for such studies poses challenges, possibly leading to incomplete clinical readings and delaying accurate data collection...

The use of cosmeceutical ingredients has experienced substantial growth over time, and there is a continuous pursuit of new active agents within the cosmetics industry. Although many of these ingredients demonstrate promising outcomes in laboratory experiments (in-vitro data), there is often a lack of clinical data to substantiate their claims. Add...

Background: The effectiveness of medicines and cosmetics on hair growth can be evaluated with the aid of many clinical hair procedures. However, there are very less qualitative approaches that are seldom available to evaluate standardization and validation and validated in any significant way. The purpose of this validation test was to Aims: assess...

Claims on overall performance, liking, preference, and efficacy can be challenged through the Advertising Standard Council of India (ASCI), a self-regulatory system for the industry. Stated claims are supported by data that are statistically evaluated to judge if the experimental results are due to a real effect or to random variation. Therefore, b...

Atopic dermatitis is a common condition characterized by pruritus, inflammation, and dryness of the skin. Inflammation disrupts the barrier function of the stratum corneum, predisposing the skin to be dry, and increasing susceptibility to irritants and secondary bacterial infection. The objective of this study was to evaluate the Synergy, Safety, a...

The objective of this study was to evaluate the effectiveness of test product in children from 3 months to 5 years with acute cold symptoms for relief from respiratory nasal congestion, keeping child calm, sooth and relax, easing discomfort and aids easy breathing, peaceful and restful night sleep, moisturizing, mildness and gentleness. This was an...

The objective of the study was to determine the efficacy of test treatment in symptomatic pain relief of acute musculoskeletal pain conditions or acute sports injuries and to evaluate the safety of the test treatment in 2 groups namely Group 1: Acute musculoskeletal pain (Backache, joints pain, neck pain, shoulder pain, etc.), sprain, strains and G...

January 2023 Updates - Annual Training on Image-Pro Software - Dr Nayan Patel's attended Ahmedabad Family Physicians Association [AFPA-NATCON 2023] conference which aimed to improve the quality of life of the people of India through by fostering & maintaining high standards of care in family medicines by promoting personal, comprehensive & continu...

It was a randomized, placebo-controlled, double-blind, two–arm, single-centre, proof-of-concept safety, and clinical efficacy study The objective of this study was to evaluate the effectiveness of the SesZen-Bio™️ in Healthy Human Subjects with adequate representation of change in hair density, thickness and scalp condition and reduction of facial...

Background: There is an explosion of cosmeceuticals and hair products in the modern world. Despite the high prevalence and impact on quality of life, there are no gold standards for qualitative and quantitative methods are established available for standardization and validation purposes Aims: This study aimed to standardize the hair tests and met...

It was an open-label, single-arm, single-centre, proof-of-concept, and efficacy, clinical study. The objective of this study was to evaluate the determine efficacy of test products for Long Lasting Effect in Healthy Human Females Subjects. A total of 32 female subjects ages 18 to 47 years were enrolled, and 32 subjects have completed the study. Thi...

“Clinically Proven” Claim - Scientific Indication The claim ‘clinically proven’ has become very in demand with marketers of both therapeutic and cosmetic products. This is likely due to the fact that this claim may provide consumers with greater confidence in their choice of products. In reality, despite the fact that ‘what’ has been clinically pro...

The skin is unique in many ways. It is the largest body organ, after the inclusion of the subcutaneous adipose tissue, protecting against environmental stressors, thus maintaining the entire body's integrity and homeostasis. The skin quality may reflect the condition of other organs that are connected via the vast network of blood vessels and nerve...

To evaluate and compare the eye irritation/sting potential of the test products and one control product following direct instillation into the eyes of human volunteers, and to provide evidence of "Tear-Free" claim support. This clinical trial has been registered at CTRI. This was a randomized, double-blind study. Twenty (20) Test subjects/test pro...

The skin is unique in many ways. It is the largest body organ, after the inclusion of the subcutaneous adipose tissue, protecting against environmental stressors, thus maintaining the entire body's integrity and homeostasis. The skin quality may reflect the condition of other organs that are connected via the vast network of blood vessels and nerve...

The objective of this study was to evaluate the safety and efficacy of Test Product in Healthy Human Subjects with Hair Fall complaints. This was an open-label, single-arm, single-center, proof of concept, safety, and efficacy clinical study. A total of 32 subjects ages 19 to 44 years were enrolled, and 30 subjects completed the study. There were n...

The rationale of the study was to evaluate the health claims of this hair fall control oil shots which is mixture of multiple herbal oils which are well known traditionally to improve hair fall by strengthening and nourishing the hair roots and improving hair and scalp health. This clinical study was to investigate the proof-of-science, safety, and...

The rationale of the study is to evaluate health claims of this hair oil shots which is mixture of multiple herbal oils which are well known traditionally to reduce scalp dandruff by strengthening and nourishing the hair roots and improving hair and scalp health. This clinical study was to investigate the proof-of-science, safety, and efficacy of a...

The rationale of the study was to evaluate health claims of test hair oil which is a formulation of herbal and essential oil which are well known traditionally to improve hair growth by strengthening and nourishing the hair roots and improving hair and scalp health. Each herb and essential oil is useful to treat hair and scalp related diseases. Thi...

The objective of this study was to determine the tooth whitening effect and full coverage for deeper, powerful and gentle teeth cleaning using combination products ‘Teeth Whitening Pen and Ultrasonic Toothbrush’ in Healthy Human Subjects with Tooth color value of A2 or Darker. This was an open-label, single-arm, proof-of-concept, safety and efficac...

The objective of this study was to evaluate skin safety and efficacy of different formulations test product in same healthy human subjects with adequate representation of varied skin types [Normal, Oily, Dry, Combined, and Sensitive Skin]. A total of 26 subjects (13 female and 13 male subjects) ages 21 to 53 years were enrolled, and 26 subjects (13...

The objective of the study was to assess the in-vitro reduction of a microbial population of test organisms after exposure to the Test Product. The primary purpose of the Germ Kill Test Study was to provide a set of standardized conditions and test organisms to facilitate comparative assessments of antimicrobial materials miscible in aqueous system...

The objective of this study was to evaluate the safety and efficacy of Test Product in Healthy Human Subjects with adequate representation of varied skin types [Normal, Oily, Dry, Combined, and Sensitive skin]. This was an open-label, single-arm, single-center, proof of concept, safety, and efficacy clinical study. A total of 38 subjects (06 males...

The objective of this study was to evaluate skin safety and efficacy of different formulations test products in same healthy human subjects with adequate representation of varied skin types [Normal, Oily, Dry, Combined, and Sensitive Skin]. A total of 26 subjects (13 female and 13 male subjects) ages 21 to 53 years were enrolled, and 26 subjects (1...

This was a randomized, double-blind study. Twenty (20) Test subjects/test product were enrolled from a population of healthy male and female (non-pregnant) subjects, 18 to 65 years of age. Pregnant and/or breastfeeding women were not admitted into the study. Prior to the selection of a subject, a Medical History Form was obtained, reviewed and main...

The objective of this study was to evaluate the safety, efficacy, and skin compatibility of the Test treatment Daily Lotion on mild to moderate Atopic Dermatitis symptoms in children and Adults in an 8-week home use test. This was an open-label, single-arm, single-centre, safety and efficacy, skin compatibility clinical study. A total of 33 subject...

We are witnessing a growing demand for standardization and objective assessment of different physiologic & pathologic conditions as well as for monitoring the efficacy of different therapeutic modalities. In the era of evidence-based medicine, we see the same trend followed by cosmetic studies too. There are devices which were invented in the past...

The objective of this study was to evaluate the synergy, safety, and efficacy of Test Treatment on healthy human subjects affected by functional constipation in children and adults. This was a double-blind, three-arm, single-centre clinical study to evaluate the synergy, safety, and efficacy of Test Treatment and between other treatments. A total o...

Research This was an open-label, single-arm, proof-of-concept, safety, and efficacy clinical study of test treatment in improving overall health and well-being in healthy adult human subjects with ANIDRA (difficulty falling asleep). The clinical trial has been registered at CTRI [Clinical Trial Registry of India]. The objective of this study was to...

The objective of this study was to determine the potential of the test products to cause cutaneous irritation in adult human subjects after single 24-hours occluded patch application. This was a single-centre, evaluator-blinded, dermal safety and skin compatibility testing study in adult healthy human subjects. One 24-hour application of 20 test pr...

The objective of this study was to determine the safety and effectiveness of the test baby diaper on the skin of 0 to 36 months old healthy babies and babies with atopic dermatitis after usage of a consecutive 2-weeks. This was an open-label, single-arm, safety, and efficacy clinical study. The paediatrician's assessment evaluated the test diapers...

Andrographis paniculata is an important medicinal plant of Andrographis genus. It is known as Kalmegh or kariyat. A. paniculata is an annual, branched, erect, and herbaceous plant. This plant grows abundantly in Southern and Southeastern Asia including India, Java, Sri Lanka, Pakistan, and Indonesia. Andrographis leaf and stem helps in stimulating...

The study was to determine the safety and effectiveness of the synergetic usage of the test treatment on healthy adult human subjects having hair fall complaints. This was an open-label, single-arm, proof of concept safety, and efficacy clinical study. A total of 12 subjects with age groups 18 years to 65 years healthy males and non-pregnant/non-la...

PCOD or PCOS is a condition that affects women's ovaries, the reproductive organs that produce progesterone and estrogen hormones that help in regulating the menstrual cycle and also produce small amount of hormones inhibin, relaxin, and male hormones called androgens. Almost 10% of women in the world is suffering from PCOD. In compare to PCOD wome...

Standardization is the best approach to maximize compatibility, inter-observer variability, inter-staff variability, repeatability and verify the quality of the processes. This research study article describes the standardization process for patch testing studies. The objective of the study was to standardize and validate the patch test methods and...

Herbal immunomodulator is substance which stimulates or suppresses the components of immune system including both innate and adaptive immune responses. The modulation of immune system by various medicinal plant products has become subject for scientific investigations currently worldwide. A number of Indian medicinal plants and various ‘Rasayana’ h...

An increasing number of noninvasive methods have been developed to determine skin properties in an objective way. The subjective, visual or tactile evaluation of skin conditions can now be quantified and numerical values can be obtained. These techniques are particularly useful in cosmetic/topical drug product testing methods such as efficacy test...

There is no specific antiviral medicines are available which prevents complications in #dengue. Only symptomatic treatment of dengue is available in the market such as Acetaminophen (Paracetamol) is used to treat a high-grade fever. Fluids are given if there are signs of dehydration. Some cases require platelet infusions and fluid management. Dengu...

The Presentation explain about Atopic Dermatitis and its evaluation test methods. This presentation was used to train research staff for scoring on SCORAD Index and EASI scales. 10 live patients were scored by trainee staff and the Dermatologist separately. Inter-Observer variability has been established between trainee staff and Dermatologist to c...

The Presentation explains the Anatomy and physiology of Skin, Scalp and Hair. This presentation was used to train research staff for anatomy, physiology and morphology of skin, hair and hair growth phase. Theoretical training was given to the study staff before doing any practical scoring, test evaluations.

The Presentation explains test methods for hair growth products. This presentation was used to train research staff for various hair testing methods used for the evaluation of hair growth products. Various test methods were done on 10 volunteers by study staff and the Dermatologist separately. Inter-Observer variability has been established between...

Brahmi (Bacopa monnieri)-Ayurveda's Favorite Child-Herb of Grace Brahmi-the name of the plant is derived from lord Brahma, the god of creativity. It is a unique herb which is known for its adaptogenic properties and brain booster medicine. This magical herb is called Ayurveda's favourite child. Bacopa is always approached in the religious, social,...

Dandelion is a plant with yellow flowers. Taraxacum officinale is the most common variety of this plant, and it grows in many parts of the world. Taraxacum is a large genus of flowering plants in the family Asteraceae, which consists of species commonly known as dandelions. The scientific and hobby study of the genus is known as taraxacology. Leave...

In the last years, consumers are paying much more attention to natural medicines and principles, mainly due to the general sense that natural compounds are safe. On the other hand, there is a growing demand by industry for plants used in traditional medicine that could be incorporated in foods, nutraceuticals, cosmetics, or even pharmaceuticals. Gl...

Fenugreek is a clover-like herb native to the Mediterranean region, southern Europe, and western Asia. Its seeds, which smell and taste like maple syrup, have been used in cooking and as medicine. Fenugreek is used as an ingredient in spice blends and a flavouring agent in foods, beverages, and tobacco.

Before an individual can manifest an allergic reaction to a locally applied agent, he normally develops hypersensitivity to the agent. In biological terms, this means that some lymphocytes in the blood acquire the capability of recognizing and reacting with the same chemical whenever and wherever that chemical is applied on the skin. An individual...

Bacopa (Bacopa monnieri) is a plant that has been used for centuries in traditional Ayurvedic medicine. It is sometimes called Brahmi. Bacopa might increase certain brain chemicals that are involved in thinking, learning, and memory. It might also protect brain cells from chemicals involved in Alzheimer disease. Bacopa is commonly used for Alzheim...

Safety-In-Use studies assess the potential for a product to elicit adverse reactions under normal use conditions. These tests are highly effective in helping determine the safety and assessing consumer perception. All safety-in-use (SIU) studies follow a common design theme.Bureau of Indian Standards, PCD19, IS 4011:2018

Of all the herbs used within Ayurveda, Tulsi (Ocimum sanctum Linn) is preeminent, and scientific research is now confirming its beneficial effects. Tulsi is an aromatic shrub in the basil family Lamiaceae (tribe ocimeae) that is thought to have originated in north-central India and now grows native throughout the eastern world tropics. Tulsi has b...

Ashwagandha is an evergreen shrub that grows in Asia and Africa. It is commonly used for stress. Its botanical source is Withania Somnifera, (family – Solanaceae) and it is a very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic).). It is used for various kinds of disease processes and especially as a nervine tonic. It i...

NovoBliss Research - Contract Research Organization (CRO) carrying out high-performance clinical research and clinical trial activities for Nutraceuticals | Natural Health Products | Dietary Supplements | OTC | Dermatology | Pharmaceutical | Cosmetics | Personal Healthcare industries. NovoBliss specializes in addressing all matters related to safet...

Hypoallergenic Cosmetics, baby care products, Fabrics - are products that manufacturers claim produce fewer allergic reactions than other products. Consumers with hypersensitive skin, and even those with "normal" skin, may be led to believe that these products will be gentler to their skin than non-hypoallergenic cosmetics.

Winter brings changes in humidity and temperature that create perfect conditions for causing dry skin, also known as Xerosis. The outermost layer of the skin is called the epidermis. The thin outer surface of the epidermis is the stratum corneum, also known as the skin barrier. Various treatments can replenish the moisture of the skin and relieve t...

Dry skin is common in the general population. Dry skin can be a simple status of the skin and does not necessarily reflect any cutaneous disease. Very dry skin, common at certain ages or environmental conditions, can, however, stimulate skin disease. Certain cutaneous diseases show scaly and dry skin as a primary clinical manifestation. Finally, I...

Background: Acne is a chronic inflammatory skin condition that causes spots and pimples on the face due to excessive skin sebum. Objectives: To evaluate efficacy and safety of Rosa T Mild Cleanser and Rosa T Serum in volunteers with mild to moderate facial acne lesions with oily skin/excessive skin sebum. Methods: 37 subjects were randomized in a d...

The objective of this validation study is to standardize the methods, procedural steps and validate the positive and negative controls and evaluations techniques that are used during the conduct of Primary Irritation Patch Test (PIPT) studies at by NovoBliss Research by 24 Hours Patch Test Under Complete Occlusion on healthy adult human subjects an...

The glycemic index is a measure of how quickly a food causes our blood sugar levels to rise. The measure ranks food on a scale of zero to 100. Foods with a high glycemic index, or GI, are quickly digested and absorbed, causing a rapid rise in blood sugar. #Invivo #GlycemicIndex (GI) testing, where we test foods for their #glycemicindex, #insulinind...

Background Acne vulgaris is a chronic, inflammatory skin condition of pilosebaceous units. The standard treatment involves topical and oral antibiotics, retinoids, benzoyl peroxide, and other synthetic compounds, mostly associated with adverse effects. Hence, herbal skincare products are considered nowadays. Aim To evaluate the safety and efficacy...

Background: Dry skin is an uncomfortable condition marked by scaling, itching, and cracking. Objectives: To evaluate the safety and efficacy of Primrose E Radiant Skin Serum in subjects with moderate to severely dry skin and sensitive skin. Methods: The study was conducted on 24 healthy female subjects, aged≥30 to≤55 years. Each subject applied a t...