How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
My research interests span in a wide range of fields under the label of 'light-matter interaction'. During my postgraduate studies so far I have mainly dealt with non linear optics, ultrafast spectroscopy, microscopy and nanoplasmonics. My PhD project served the investigation of cellular uptake of various sizes gold NPs via Four-wave mixing (FWM) imaging and correlation with fluorescence microscopy.
October 2014 - March 2017
February 2014 - May 2018
- PhD Student
- The aim of my PhD project is to track gold nanoparticles while undergoing endocytosis as well as to understand and control receptor-mediated transport pathways for therapeutic delivery. Main method: Four-Wave mixing
Gold nanoparticles have been researched for many biomedical applications in diagnostics, theranostics, and as drug delivery systems. When conjugated to fluorophores, their interaction with biological cells can be studied in situ and real time using fluorescence microscopy. However, an important question that has remained elusive to answer is whethe...
Single nanoparticle tracking using optical microscopy is a powerful technique with many applications in biology, chemistry and material sciences. Despite significant advances, localising objects with nanometric position accuracy in a scattering environment remains challenging. Applied methods to achieve contrast are dominantly fluorescence based, w...
Latest results on imaging the cellular uptake of various ligand coated gold nanoparticles (40nm and 15nm diameter) via resonant dual-polarisation four-wave mixing technique and confocal microscopy.
We demonstrate Time-Correlated Single Photon Counting (TCSPC) in microfluidic droplets in high throughput conditions. We discuss the fundamental limitations in the photon acquisition rate imposed by the single photon detection technique and show that it does not preclude accurate fluorescence lifetime (FLT) measurements at a droplet throughput exce...
The nonlinear optical properties of a series of novel boron dipyrromethene derivatives (BODIPY) are investigated by means of the Z-scan technique under 4 ns and 35 ps, visible and infrared laser pulses. All studied BODIPYs were found to exhibit strong saturable absorption and insignificant nonlinear refraction under visible excitation, while no res...