Naveena Kumar A.N.

Naveena Kumar A.N.
Manipal Academy of Higher Education | MAHE · Department of Surgical Oncology

MBBS, MS, MCh Surgical oncology, Fellowship in GI and Colorectal Oncology and Laparoscopic and Robotic Surgery

About

26
Publications
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101
Citations
Introduction
Naveena Kumar A.N. currently works at the Department of Surgical Oncology, Manipal Academy of Higher Education. Naveena does research in Gastroenterology, Surgery and Oncology. Their current project is 'Minimal invasive surgery (MIS) for pelvic exenteration in locally advanced Colorectal cancer'.

Publications

Publications (26)
Article
Abstract Background: This study was undertaken to evaluate the effect of change in policy of computed tomography (CT) scan of the thorax in staging and follow‐up of colorectal cancer (CRC). Another objective was to review the outcomes following pulmonary metastasectomies (Pmets) and to determine the prognostic factors affecting outcomes. Methods: T...
Article
Introduction: This study reports the clinicopathological characteristics and the perioperative and long-term treatment outcomes after aggressive surgical resection in solid pseudopapillary tumor (SPT) of the pancreas performed at a high volume center for pancreatic surgery in India. Materials and methods: We analyzed a prospectively maintained d...
Article
Background: Tata Memorial Centre (TMC) is a high-volume centre for pancreatic tumour resections. We found a continually increasing referral of pancreatic tumours for re-evaluation for surgery, after an initial unsuccessful attempt at resection. Aim: To evaluate reasons of initial in-operability, the feasibility of re-operative pancreatico-duoden...
Article
The stomach remains the most preferred esophageal substitute following esophagectomy for cancer [1]. However in circumstances where the stomach is not available due to involvement by the cancer, such as in our patient, or due to prior surgery, a few other options are still available. While the jejunum is suitable to reconstruct total gastrectomy an...
Article
Full-text available
Purpose There has been an increase in the incidence of signet ring cell cancer (SRCC) of the stomach and gastro-esophageal junction (GEJ). The multistage carcinogenesis involving genetic and epigenetic aberrations may have a major role in the increasing incidence of SRCC. Although there are numerous studies on the prognostic value of SRCC, they are...
Article
Laparoscopic total mesorectal excision (TME) is the standard of care for resectable rectal cancer [1,2]. The quality of oncological resection and short term benefits have improved with skilled laparoscopic surgery [1,2]. Performing laparoscopic TME and sphincter preservation in low rectal cancer is technically demanding. Adaptation to standard surg...
Article
Full-text available
The complete mesocolic excision (CME), first described by Hohenberger et al. involves dissection in the embryological plane between mesocolic and retroperitoneal fascia to remove an intact envelope of mesocolon, central vascular ligation (CVL), resection of sufficient length of proximal and distal bowel, and adequate clearance of draining lymph nod...
Article
Full-text available
Purpose This study compares the short- and long-term outcomes between the left thoraco-abdominal and trans-abdominal approaches for radical resection of adenocarcinoma of the gastro-esophageal junction (GEJ) (Siewert types II and III) following neo-adjuvant chemotherapy. Methods A retrospective analysis of a prospectively maintained database of pa...
Article
Full-text available
Purpose The aim was to evaluate the oncological outcomes and the prognostic factors following pelvic exenteration (PE) in cT4 and fixed cT3 stage primary rectal adenocarcinoma and to study the impact of consolidation chemotherapy following neoadjuvant concurrent chemoradiotherapy (NACRT). Methods A retrospective analysis of a prospectively maintai...
Article
Full-text available
Letrozole, an aromatase inhibitor (AI), is the first-line adjuvant drug for treating hormone receptor-positive (HR+) breast cancer in postmenopausal women. However, harmful adverse events (AEs) and significant differences in drug response among individuals remain a significant problem in clinical application. Current evidence suggests that the obse...
Article
I read with interest the Article by Renu Bahadoer and colleagues1 in The Lancet Oncology, which reported results of the phase 3 RAPIDO trial in locally advanced rectal cancer. I applaud the authors' work and agree with their conclusion, but I have concerns regarding the use of the RAPIDO protocol for patients with stage cT4 low rectal cancer with p...
Article
Full-text available
IntroductionTotal pelvic exenteration (TPE) for rectal cancers is associated with significant morbidity. We evaluated the complications related to urinary reconstruction following TPE and factors predicting urologic morbidity.Methods Retrospective analysis of TPE patients with incontinent urinary diversions between August 2013 and January 2020.Resu...
Article
Breast cancer patients need to be on regular follow-up after definitive treatment, for early detection and treatment of recurrence or distant metastasis. Gastrointestinal and peritoneal metastases from breast cancer are rare. Invasive lobular carcinoma has a tendency to spread to the gastrointestinal organs, and usually, is present a few years afte...
Article
Full-text available
Lysine-specific demethylase 5B (KDM5B/PLU1/JARID1B) is found to be overexpressed in numerous malignancies, including breast, lung, skin, liver, and prostate cancer. Identification of molecules targeting the KDM5B enzyme could be a potential lead in cancer research. Although many KDM5B inhibitors with promising outcomes have been developed so far, i...
Article
Many retrospective series have been reported on the outcomes of tracheal resection for adenoid cystic carcinoma. However, demonstration on techniques of surgery and ventilatory management during the procedure are rare. We, herewith demonstrate a surgical video, wherein a distal tracheal resection was performed through right posterolateral thoracoto...
Article
Full-text available
Background: Minimally invasive surgery (MIS) for pelvic exenteration is not a well-established technique. The aim was to assess the safety and feasibility of MIS for pelvic exenteration in locally advanced primary colorectal cancer and to compare the perioperative outcomes with open surgery. Methods: This is a retrospective analysis of patients,...
Article
Robotic surgery has helped surgeons with complex surgeries in anatomically restricted areas. As experience grows with the robotic platform, pushing the surgical boundaries for better patient outcomes is natural. We have previously published our standardized techniques of total pelvic exenteration(1) and pelvic node dissection in locally advanced re...
Article
Incidence of synchronous peritoneal metastases (PM) in colorectal cancer is approximately 5%, with another 5% of the patients develop metachronous PM. Colorectal PM has been hypothesized to be a loco-regional disease rather than a systemic spread, and cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has been consid...
Article
Full-text available
How to cite this article: Kumar NAN, Kammar P, Saklani A. Minimal invasive approach for beyond total mesorectal excision/ extended resections in rectal cancer. Mini-invasive Surg 2018;2:xx. http://dx. Abstract Minimal invasive surgery (MIS) is an accepted modality of treatment for rectal cancer. The indications for MIS have gradually been extended...
Article
Aim: Tata Memorial Hospital is one of the high-volume tertiary care referral centers for gastric cancer (GC) in India. We aimed to analyze the outcomes after surgery for GC. Patients and methods: Data were collected from the prospective database maintained by the Gastrointestinal and Hepato-Pancreato-Biliary Division of the Department of Surgica...
Conference Paper
Objective: Single nucleotide polymorphisms (SNPs) of CYP19A1 have been implicated in relation to breast cancer risk and therapeutic outcome. Hence, the objective of the study was to determine the allele and genotype frequencies, linkage disequilibrium (LD) patterns and haplotype structures of CYP19A1 gene located on chromosome 15q21 in South Indian...

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