Natascha Turetzek

Natascha Turetzek
Ludwig-Maximilians-University of Munich | LMU · Department of Biology II - Evolutionary Ecology - AG Gompel

MSc, Dr.
Akademische Rätin @LMU München, Research Associate

About

96
Publications
7,355
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
525
Citations
Citations since 2016
72 Research Items
481 Citations
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
Introduction
Natascha currently is Research Associate at the Gompel Lab/ LMU and interested in Evolutionary Developmental Biology, Neurobiology and Bioinformatics. She did her PhD and a Post-Doc at the Georg-August-Universität Göttingen. Her PhD project in the Prpic Lab was 'Genetic causes of morphological diversification'. Using different spider models she investigated the conservation of gene regulatory networks important for appendage development, using molecular cloning, WMISH, RNA-seq and de novo transcriptome assembly. For her Post-Doc project in the Department of Cellular Neurobiology she performed transcriptional profiling of the the Fly's ear, the Johnson's Organ, from Drosophila melanogaster, to identify similarities and differences between the neuronal subpopulations.
Additional affiliations
August 2018 - present
Ludwig-Maximilians-University of Munich
Position
  • Research Associate
February 2017 - July 2018
Georg-August-Universität Göttingen
Position
  • PostDoc Position
April 2016 - December 2016
Georg-August-Universität Göttingen
Position
  • PostDoc Position
Education
November 2011 - March 2016
Georg-August-Universität Göttingen
Field of study
  • Evolutionary Developmental Biology
October 2009 - October 2011
Georg-August-Universität Göttingen
Field of study
  • Developmental, Neural and Behavioral Biology
October 2006 - September 2009
Georg-August-Universität Göttingen
Field of study
  • Molecular Biology

Publications

Publications (96)
Article
Full-text available
The model organism Drosophila melanogaster has become a focal system for investigations of rapidly evolving genital morphology as well as the development and functions of insect reproductive structures. To follow up on a previous paper outlining unifying terminology for the structures of the male terminalia in this species, we offer here a detailed...
Preprint
Spiders are a diverse order of chelicerates that diverged from other arthropods over 500 million years ago. Research on spider embryogenesis has made important contributions to understanding the evolution of animal development. In particular, studies of the common house spider Parasteatoda tepidariorum using developmental candidate gene approaches...
Preprint
Full-text available
Mating systems, with varying female mating rates occurring with the same partner (monogamy) or with multiple mates (polyandry), can have far reaching consequences for population viability and the rate of gene flow. Here, we investigate the mating system of the common house spider Parasteatoda tepidariorum (Theridiidae), an emerging model for geneti...
Preprint
Full-text available
The model organism Drosophila melanogaster has become a focal system for investigations of rapidly evolving genital morphology as well as the development and functions of insect reproductive structures. To follow up on a previous paper outlining unifying terminology for the structures of the male terminalia in this species, we offer here a detailed...
Article
Full-text available
Paired box genes are conserved across animals and encode transcription factors playing key roles in development, especially neurogenesis. Pax6 is a chief example for functional conservation required for eye development in most bilaterian lineages except chelicerates. Pax6 is ancestrally linked and was shown to have interchangeable functions with Pa...
Preprint
The model organism Drosophila melanogaster has become a focal system for investigations of rapidly evolving genital morphology as well as the development and functions of insect reproductive structures. To follow up on a previous paper outlining unifying terminology for the structures of the male terminalia in this species, we offer here a detailed...
Preprint
Full-text available
The model organism Drosophila melanogaster has become a focal system for investigations of rapidly evolving genital morphology as well as the development and functions of insect reproductive structures. To follow up on a previous paper outlining unifying terminology for the structures of the male terminalia in this species, we offer here a detailed...
Article
Full-text available
In the arthropod model species Drosophila melanogaster , a dipteran fly, segmentation of the anterior–posterior body axis is under control of a hierarchic gene cascade. Segmental boundaries that form morphological grooves are established posteriorly within the segmental expression domain of the segment-polarity gene (SPG) engrailed ( en ). More imp...
Article
Full-text available
The Wnt genes represent a large family of secreted glycoprotein ligands that date back to early animal evolution. Multiple duplication events generated a set of 13 Wnt families of which 12 are preserved in protostomes. Embryonic Wnt expression patterns (Wnt-patterning) are complex, representing the plentitude of functions these genes play during de...
Article
Full-text available
Spider-Man gets his special powers from a spider bite. Real spider males do not have special powers, but they do have a specialized organ that female spiders do not have. It is called the bulbus organ, and it is needed for mating and thus really important. It is fascinating that the bulbus organ is absent in young spiders and has to develop inside...
Article
Full-text available
The Hox gene labial (lab) governs the formation of the tritocerebral head segment in insects and spiders. However, the morphology that results from lab action is very different in the two groups. In insects, the tritocerebral segment (intercalary segment) is reduced and lacks appendages, whereas in spiders the corresponding segment (pedipalpal segm...
Article
Full-text available
Abstract Forkhead box (Fox) transcription factors evolved early in animal evolution and represent important components of conserved gene regulatory networks (GRNs) during animal development. Most of the researches concerning Fox genes, however, are on vertebrates and only a relatively low number of studies investigate Fox gene function in invertebr...
Article
Full-text available
The discovery of a gene that regulates two segmentation mechanisms in spider embryos is fueling the ongoing debate about the evolution of this crucial developmental process.
Article
Full-text available
Homeobox genes are key toolkit genes that regulate the development of metazoans and changes in their regulation and copy number have contributed to the evolution of phenotypic diversity. We recently identified a whole genome duplication (WGD) event that occurred in an ancestor of spiders and scorpions (Arachnopulmonata), and that many homeobox gene...
Article
Full-text available
Zinc finger transcription factors of the Sp6-9 group are evolutionarily conserved in all metazoans and have important functions in, e.g., limb formation and heart development. The function of Sp6-9-related genes has been studied in a number of vertebrates and invertebrates, but data from chelicerates (spiders and allies) was lacking so far. We have...
Article
Full-text available
Background: The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate lineages including two rounds of whole genome duplication (WGD) in horseshoe crabs. To investi...
Article
Full-text available
Background Gene duplications provide genetic material for the evolution of new morphological and physiological features. One copy can preserve the original gene functions while the second copy may evolve new functions (neofunctionalisation). Gene duplications may thus provide new genes involved in evolutionary novelties. Results We have studied th...
Data
Species abbreviations and sequence sources used in the phylogenetic analyses. (DOCX 129 kb)
Data
Alignment of metazoan hth-related protein sequences used in the phylogenetic sequence analysis in Nexus format. (NEX 25 kb)
Data
Phylogenetic analysis of hth and related nucleotide sequences from diverse Metazoa. Unrooted 50% majority rule consensus tree after Bayesian Markov chain Monte Carlo analysis. Branch lengths in the phylogram give the expected substitutions per site. Numbers at the tree edges are clade credibility values, which are a measure of the probability of ea...
Data
Alignment of Hth1 proteins from four spider species. Abbreviations: Pp, Pholcus phalangioides; Cs, Cupiennius salei; Ag, Acanthoscurria geniculata; Pt, Parasteatoda tepidariorum. Dashes in the alignment denote gaps introduced to improve the alignment. (DOCX 125 kb)
Data
Alignment of metazoan hth-related nucleotide sequences used in the phylogenetic sequence analysis in Nexus format. (NEX 63 kb)
Data
Location of the RNA probes indicated on the mRNA sequence of the individual hth genes to indicate the overlap with conserved domains. The protein coding sequence (CDS) is shown in bold type, red colour indicates the location of the Meis domain, and blue colour indicates the location of the homeodomain. The location of the probe is mapped onto the s...
Data
Alignment of Hth2 proteins from four spider species. Abbreviations: Pp, Pholcus phalangioides; Cs, Cupiennius salei; Ag, Acanthoscurria geniculata; Pt, Parasteatoda tepidariorum. Dashes in the alignment denote gaps introduced to improve the alignment. (DOCX 126 kb)
Preprint
Full-text available
The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate lineages including two rounds of whole genome duplication (WGD) in horseshoe crabs. To investigate this fu...
Article
Full-text available
Most recent studies of spider embryonic development have focused on representatives of the species-rich group of entelegyne spiders (over 80 % of all extant species). Embryogenesis in the smaller spider groups, however, is less well studied. Here, we describe the development of the germ band in the spider species Pholcus phalangioides, a representa...
Article
Full-text available
The acquisition of a novel function, or neofunctionalization, protects duplicated genes from redundancy and subsequent loss, and is a major force that drives adaptive evolution. Neofunctionalization has been inferred for many duplicated genes based on differences in regulation between the parental gene and its duplicate. However, only few studies a...
Article
Full-text available
The intercalary segment is a limbless version of the tritocerebral segment and is present in the head of all insects, whereas other extant arthropods have retained limbs on their tritocerebral segment (e.g. the pedipalp limbs in spiders). The evolutionary origin of limb loss on the intercalary segment has puzzled zoologists for over a century. Here...
Data
Full-text available
Supplementary Material - Detailed methods, supplementary figures and legends
Article
Full-text available
Wnt signaling regulates many important processes during metazoan development. It has been shown that Wnt ligands represent an ancient and diverse family of proteins that likely function in complex signaling landscapes to induce target cells via receptors including those of the Frizzled (Fz) family. The four subfamilies of Fz receptors also evolved...
Article
Full-text available
Background Two visual systems are present in most arthropod groups: median and lateral eyes. Most of our current knowledge about the developmental and molecular mechanisms involved in eye formation in arthropods comes from research in the model system Drosophila melanogaster. Here, a core set of retinal determination genes, namely, sine-oculis (so)...