Natalie L Milic

• Charles Darwin University

This descriptive study examined the variation in ventral Crocodylus porosus (saltwater crocodile) belly skin. The study is the first to determine both intra and inter variation of C. porosus skin, epidermis and dermis thickness across the ventral belly region. Standardised ventral scales from across the belly region of a Hatchling (< 12months), Yea...

Background: Circulating microRNAs (miRNAs) are potential molecular biomarkers for cancer detection; however, little is known about their prognostic role in head and neck cancer. This current study is aimed at evaluating the role of novel miRNAs in the survival of head and neck cancer patients. Materials and methods: We performed a systematic lit...

Background The global crocodilian skin market is currently in oversupply. As a result, the tanneries can now be very selective about the quality of skins they purchase. The challenge to producers is to meet these quality standards. A part of this challenge is to understand the risk of pathogens to crocodile skin quality. Aims/objectives Collective...

Background: MicroRNAs (miRNAs) have been found to play an important role in the development and outcomes for multiple human cancers. Their role as a prognostic biomarker in non-small-cell lung cancer (NSCLC) remains unclear. This meta-analysis aims to clarify the role of various miRNAs in the survival of NSCLC patients. Materials and methods: Al...

Cystic Fibrosis is an autosomal recessive disorder with no cure. It is one of the most common life-shortening genetic diseases in the Caucasian population, affecting more than 75000 individuals worldwide. This inherited multi-organ disease is associated with chronic lung infection, malabsorption, salt loss syndrome, infertility and numerous other c...

Crocodilepox virus is a large dsDNA virus belonging to the genus Crocodylidpoxvirus, which infects a wide range of host species in the order Crocodylia worldwide. Here, we present genome sequences for a novel saltwater crocodilepox virus, with two subtypes (SwCRV-1 and -2), isolated from the Australian saltwater crocodile. Affected belly skins of j...

Crocodilepox virus is a large dsDNA virus belonging to the genus Crocodylidpoxvirus, which infects a wide range of host species in the order Crocodylia worldwide. Here, we present genome sequences for a novel saltwater crocodilepox virus, with two subtypes (SwCRV-1 and -2), isolated from the Australian saltwater crocodile. Affected belly skins of j...

In the Northern Territory (NT) and Queensland, Australia, estuarine crocodiles (Crocodylus porosus) are farmed mainly for their skin. There are several types of skin blemishes that reduce the value of hides and the search for a specific causal agent continues. Concomitantly, the acknowledged role of the microbiota in maintaining animal health has l...

Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. We have previously reported the cloning and characterisation of the koala CYP4A15, the first reported member of the CYP4 family from marsupials, and have demonstrated important species differences in CYP4A activi...

Online technology is increasingly used in higher education and training. Recent advances in information and communication technologies (ICTs) have enabled the implementation of an array of tools, such as online tutorials, videos, podcasts and vodcasts, which are utilised within the education and business sectors. In this chapter the authors describ...

The cytochrome P450 4B subfamily (CYP4B) exhibits bioactivation of aromatic amines and species- and tissue-specific regulation. For many years, CYP4B1 was the only gene represented within this family, often referred to as a lung-specific enzyme. A second member, CYP4B2, was subsequently isolated from goat lung1. Hypothesis: This study aimed to inve...