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Publications (32)
Pyometra is an acute or chronic suppurative infection with accumulation of pus in the uterine lumen in predominantly middle‐aged to aged bitches. Pyometra has initially been described as a condition of older, ovary‐intact bitches that still undergo estrous cycles. Pyometra is believed to be facilitated by the unique canine estrous cycle, during whi...
Increased ambient temperatures has been identified to contribute to reproductive outcomes for several domesticated species, but its impact on equine reproduction has not been previously investigated. Therefore, this study aimed to examine the relationship between ambient climatic conditions, as measured by temperature-humidity index (THI) between d...
Clinical case presentations detail unique and clinically relevant anatomical features about the canine and feline distal colon and rectum, female and male reproductive systems, mammary glands, and the urinary system.
Clinical case presentations detail unique and clinically relevant anatomical features about the canine and feline distal colon and rectum, female and male reproductive systems, mammary glands, and the urinary system.
Clinical case presentations detail unique and clinically relevant anatomical features about the canine and feline distal colon and rectum, female and male reproductive systems, mammary glands, and the urinary system.
Clinical case presentations detail unique and clinically relevant anatomical features about the canine and feline distal colon and rectum, female and male reproductive systems, mammary glands, and the urinary system.
Retained fetal membranes (RFM) is a common post-partum problem in mares for which the treatment is highly variable. The aim of this study was (i) to investigate the different treatments used by equine practitioners for RFM and (ii) to determine if there is a difference between treatments used by reproductive specialists and general equine practitio...
Persistent mating-induced endometritis (PMIE) severely decreases fertility in horses. The aim of the present study was to evaluate differences between horses susceptible to PMIE and a control group in terms of the expression of selected immune response and effector genes, and the effects of oestrous cycle stage on this expression. Endometrial biops...
Infectious endometritis is a major cause of reduced pregnancy rates in horses. The objectives of this study were to establish a timeline of the innate immune response in the uterus of healthy horses and to investigate the oestrous cycle effect on this. Endometrial biopsies were collected from five horses before and at 3, 12, 24, 48 and 72 h after i...
Aims:
To describe selected periparturient variables in a sample of Thoroughbred mares and their foals on a commercial stud farm in New Zealand.
Methods:
Data were collected for 969 foaling records, from 592 mares, by foaling attendants from one Thoroughbred stud farm in the Waikato region of New Zealand for the breeding seasons 2008-2013, inclus...
Practical relevance
Pyometra is a commonly occurring uterine disease in cats that often leads to loss of breeding potential and, in some cases, can be life threatening. An increased incidence of cystic endometrial hyperplasia (CEH) and pyometra is seen with age. Most queens present with uterine lesions after 5–7 years of age (average 7.6 years, ran...
Background:
The steroid hormone environment in healthy horses seems to have a significant impact on the efficiency of their uterine immune response. The objective of this study was to characterize the changes in gene expression in the equine endometrium in response to the introduction of bacterial pathogens and the influence of steroid hormone con...
Infectious endometritis is a major cause of infertility in the mare and inflicts major losses on the equine breeding industry. The ability of the mare to eliminate uterine infections has been studied intensively for decades; however, despite identification of several factors contributing to the multifactorial pathogenesis and improved treatment, in...
The physiological changes associated with the varying hormonal environment throughout the oestrous cycle are linked to the different functions the uterus needs to fulfil. The aim of the present study was to generate global gene expression profiles for the equine uterus during oestrus and Day 5 of dioestrus. To achieve this, samples were collected f...
Escherichia coli (E. coli) is the most commonly isolated infectious agent causing pyometra in bitches. Many E. coli strains isolated from the uteri of infected dogs carry several adhesin genes (fimH, papGIII and sfa). The objective of this study was to investigate the role of each adhesin gene product, acting alone or expressed in combination, in t...
Objective:
To assess pregnancy and live foaling rates after reduction of twin pregnancy via transvaginal ultrasound-guided aspiration (TUA) in mares and evaluate effects of gestational period, localization of conceptuses, fluid aspiration volume, and combination of TUA with embryonic or fetal puncture on these outcomes.
Design:
Clinical trial....
Pyometra is an acute or chronic suppurative infection with accumulation of pus in the uterine lumen in predominantly middle-aged to aged bitches. Cystic endometrial hyperplasia (CEH) and the pyometra were defined as one disease entity. It is currently believed that pyometra results from the interaction of Escherichia coli with the progesterone- inf...
Contents
Pyometra, a prevalent infectious uterine disease that affects intact middle‐aged bitches, is typically associated with E scherichia coli . Our hypotheses were (i) that bacterial adhesion to canine endometrium differs between different stages of the oestrous cycle and (ii) that the adhesin FimH facilitates this adhesion. Twelve post‐puberta...
Pyometra is a potentially life-threatening condition in bitches and is often caused by Escherichia coli infection. Both pathogenic and non-pathogenic E. coli strains commonly carry the genes for type 1 fimbriae that mediate bacterial adhesion onto host epithelium. To investigate whether the type 1 fimbrial adhesin, FimH, facilitates the binding of...
Despite the high prevalence of primary uterine inertia in whelping bitches, the underlying pathogenesis remains unclear. The objectives were to i) determine serum concentrations of total calcium, ionized calcium (iCa), parathyroid hormone (PTH), and blood pH in normally whelping bitches throughout the peri-parturient period; and ii) investigate rel...
The knobbed acrosome defect (KAD) has only once been reported in dog sperm. This report describes the breeding history, clinical presentation and semen evaluation of four closely related miniature Schnauzer dogs that had between 8 and 44% sperm with KAD. Two of the dogs had no substantial reproductive or sperm defects other than the KAD and were of...
A novel approach to estrous induction in diestrous bitches is described. Twelve spontaneously cycling anestrous bitches served as controls. Thirteen anestrous and 15 diestrous bitches were induced to come into synchronous estrous using prostaglandin (diestrous bitches only) and deslorelin implants (Ovuplant). Implants contained either 2.1 or 1.05 m...
Induction of estrus with deslorelin implants was followed by abortions in bitches that conceived during the induced estrus. Lowering the deslorelin dose and choosing a better implantation site prevented the abortions. This study investigated the hypothesis that induction of estrus with deslorelin is followed by reduced serum progesterone concentrat...
