Natali Jokanovic

Natali Jokanovic
  • BPharm(Hons), GradCertPharmPrac, MScMed(ClinEpid), PhD
  • Alfred Hospital

About

27
Publications
5,399
Reads
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1,248
Citations
Introduction
Current institution
Alfred Hospital
Additional affiliations
July 2018 - December 2018
The University of Sydney
Position
  • PostDoc
Education
August 2019 - July 2021
The University of Sydney
Field of study
  • Clinical Epidemiology
October 2014 - March 2019
Monash University (Australia)
Field of study
  • Pharmacy
January 2013 - July 2014
Monash University (Australia)
Field of study
  • Pharmacy

Publications

Publications (27)
Article
Full-text available
INTRODUCTION People with dementia and carers face challenges in understanding and managing medications at discharge. This study aimed to develop user‐centered, co‐designed medication management guidance tools to enhance medication management literacy post‐hospitalization for these populations. METHODS A four‐phase, multi‐methods study integrating...
Article
Full-text available
Background People with dementia and their care givers are provided limited guidance in medication management, potentially contributing to medication‐related harm. Importantly, there are no resources that provide comprehensive medication management guidance across care settings. To ensure that resources are co‐designed, genuine involvement of people...
Article
Background People living with dementia and their carers often experience difficulties in effectively managing medications and have indicated they lack necessary support, information and guidance. Recognising the medication management information needs of this population is an important first step in addressing these issues. Objectives To identify...
Article
Full-text available
Objectives To evaluate the need and feasibility of a nurse-led antimicrobial stewardship (AMS) programme in two Australian residential aged care homes (RACHs) to inform a stepped-wedged, cluster randomized controlled trial (SW-cRCT). Methods A mixed-methods pilot study of a nurse-led AMS programme was performed in two RACHs in Victoria, Australia...
Article
Background People with dementia are more likely to experience medication‐related harm than people without dementia at transitions of care. However, medication management guidance is often not provided to people with dementia and carers during hospitalisation. We aimed to co‐design novel medication management resources for people with dementia and c...
Preprint
Full-text available
Objective: To evaluate the feasibility of a nurse-led antimicrobial stewardship (AMS) program in two Australian residential aged care homes (RACHs) to inform a stepped-wedged, cluster randomised controlled trial (SW-cRCT). Methods: A mixed-methods pilot study of a nurse-led AMS program was performed in two RACHs in Victoria, Australia between July...
Article
Full-text available
Introduction: Globally, the rate of opioid prescription is high for chronic musculoskeletal conditions despite guidelines recommending against their use as their adverse effects outweigh their modest benefit. Deprescribing opioids is a complex process that can be hindered by multiple prescriber- and patient-related barriers. These include fear of...
Article
Full-text available
Introduction: Antimicrobial resistance is a growing global health threat, driven by increasing inappropriate use of antimicrobials. High prevalence of unnecessary use of antimicrobials in residential aged care facilities (RACFs) has driven demand for the development and implementation of antimicrobial stewardship (AMS) programmes. The Stepped-wedg...
Article
Background/Objectives Medication review is an important component of the management of older hospital patients. Deprescribing (supervised withdrawal of inappropriate medicines) is one outcome of review. This study aimed to iteratively develop and test the usability of deprescribing guides, which support multidisciplinary clinicians to reduce inappr...
Article
Full-text available
Aims The objective of this study is to investigate the association between multiple antihypertensive use and mortality in residents with diagnosed hypertension, and whether dementia and frailty modify this association. Methods This is a two-year prospective cohort study of 239 residents with diagnosed hypertension receiving antihypertensive therap...
Article
Full-text available
Objective: To develop information leaflets for older inpatients and/or their carers to support deprescribing of antipsychotics, benzodiazepines/Z-drugs and proton pump inhibitors (PPIs). Design: An iterative mixed-methods approach involving face-to-face user testing and semi-structured interviews was performed over three rounds with consumers an...
Article
Background One quarter of residents in long-term care facilities (LTCFs) have a diagnosis of CHD or stroke and over half use at least one preventative cardiovascular medication. There have been no studies that have investigated the longitudinal change in secondary preventative cardiovascular medication use in residents in LTCFs over time. Objectiv...
Article
Background: Evidence is accumulating globally on harms from extramedical prescription opioid analgesic (POA) use. Objective: The aim of this scoping review was to explore harms and documented risk factors associated with extramedical POA use in Australia. Methods: MEDLINE, EMBASE, PsycINFO and CINAHL were searched for original studies publishe...
Article
Background: Residential aged care is a complex and challenging clinical setting where medication errors continue to occur despite efforts to improve medication safety. No studies have sought to review and synthesize coronial investigations into medication-related deaths in Australian residential aged care facilities (RACFs). Objective: To review...
Article
Full-text available
Background: Research into which medications contribute to polypharmacy and the variability in these medications across long-term care facilities (LTCFs) has been minimal. Objective: Our objective was to investigate which medications were more prevalent among residents with polypharmacy and to determine the variability in prescribing of these med...
Article
Objectives: To systematically review clinical outcomes associated with medication regimen complexity in older people. Design: Systematic review of EMBASE, MEDLINE, International Pharmaceutical Abstracts, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane library. Setting: Hospitals, home, and long-term care. Participan...
Article
Background: Pharmacist-led medication review is a collaborative service which aims to identify and resolve medication-related problems. Objective: To critically evaluate published systematic reviews relevant to pharmacist-led medication reviews in community settings. Methods: MEDLINE, EMBASE, International Pharmaceutical Abstracts (IPA), Cumul...
Article
Polypharmacy is highly prevalent in residential aged care facilities (RACFs). Although polypharmacy is sometimes unavoidable, polypharmacy has been associated with increased morbidity and mortality. To identify and prioritize a range of potential interventions to manage polypharmacy in RACFs from the perspectives of healthcare professionals, healt...
Article
Rationale, aims and objectives: The prevalence of polypharmacy in residential aged care facilities (RACFs) is high and increasing. Although not necessarily inappropriate, polypharmacy has been associated with drug interactions, adverse drug events, geriatric syndromes and hospital admissions. The aim of this study was to identify and prioritize fa...
Article
There is uncertainty in relation to the effect of alcohol consumption on the incidence of dementia and cognitive decline. This review critically evaluated published systematic reviews on the epidemiology of alcohol consumption and the risk of dementia or cognitive decline. MEDLINE, EMBASE and PsycINFO were searched from inception to February 2014....
Article
Full-text available
Pain is a frequent cause of discomfort and distress in residents in residential aged care facilities (RACFs). Despite the benefits of adequate pain management, there is inconsistency in the literature regarding analgesic use and pain in residents with dementia. The aim of this systematic review was to determine the prevalence of analgesic drug use...
Article
Full-text available
Clinical medication review (CMR) is a structured and collaborative service aimed at identifying and resolving medication-related problems (MRPs). This is the first systematic review of CMR research in Australia. To systematically review the processes and outcomes of CMR in community-settings in Australia. MEDLINE, EMBASE, International Pharmaceutic...
Article
Full-text available
Introduction: It is not known to what extent medication use has been comprehensively assessed in prospective cohort studies of older Australians. Understanding the varying methods to assess medication use is necessary to establish comparability and to understand the opportunities for pharmacoepidemiological analysis. The objective of this review w...
Article
Objective: The objective of the study was to investigate the prevalence of, and factors associated with, polypharmacy in long-term care facilities (LTCFs). Methods: MEDLINE, EMBASE, International Pharmaceutical Abstracts, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library were searched from January 2000 to Septemb...
Article
Background: There is increasing awareness that medications can contribute to cognitive decline. Prospective cohort studies are rich sources of clinical data. However, investigating the contribution of medications to cognitive decline is challenging because both medication exposure and cognitive impairment can be associated with attrition of study...

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