Nasser Simforoosh

Shahid Beheshti University of Medical Sciences · urology&kidney transplantation

Objective: In this study, we aimed to compare the frequency of lymphoceles that needed intervention in recipients who received kidneys from living versus deceased donors. Materials and methods: The records of all patients who underwent kidney transplantation at the Labbafinejad Hospital from 2012 to 2021 were retrospectively reviewed to determin...

Background To compare the disease course, histopathological features and survival rates of prostate cancer (PCa) between patients aged ⩽ 55 and > 55 year old. Materials and methods In this retrospective study, we enrolled 644 patients with organ-confide prostate cancer who had undergone radical prostatectomy from 2005 to 2018. Seventy-six (11.8%)...

Objectives: To evaluate oncological outcomes in patient with positive surgical margin (PSM) following partial nephrectomy (PN). Material and methods: In this retrospective study, we enrolled the data of patients who underwent PN between 2008 and 2017. The inclusion criteria were a definite diagnosis of kidney tumor who underwent PN with at least...

Background: To study the current trends in Obstetrics–Gynecology (Ob-Gyn) education and workforce in Iran since 1979 and to discuss the consequences and implications. Methods: This descriptive-analytical study was conducted to describe the Ob-Gyn residency and fellowship growth and workforce profile in Iran (1979-2017).The first-hand data gathered...

In this comprehensive book the authors discussed the challenges and solutions for population promotion (quantitative and qualitative promotion) in Iran.

In This book, the authors discussed the population promotion challenges in Iran , and recommended the Innovative

Objective: Renal mesenchymal tumors are described as neoplasms with vascular, fibrous and adipose tissues. The renal lipoma is extremely rare renal mesenchymal tumor, typically originating from renal capsule and it is usually presented as well circumscribed homogenous fat containing mass. Angiomyolipoma (AML) is the most common benign mesenchymal...

Purpose: Data registries are organized systems that facilitate collection, storage, and analysis of data related to a specific disease in a defined population. Here we introduce a data registry system which was designed to cover the four most common urologic cancers (prostate, bladder, renal and testis). Materials and methods: All contributing c...

Iranian culture and religious teachings lead to a unique value-laden model in health and medical education systems. This research aimed to determine these fundamental values. To identify the health system values in the religious context of Iran, a mixed critical analysis–synthesis method was conducted. Furthermore, a focus group discussion with exp...

Request for kidney transplantation (K.T.) is increasing rapidly because of the worldwide pandemic of end-stage renal disease, and the most critical issue is organ shortage. The available deceased donors will not resolve the continuing scarcity of organs. It is now professionally and ethically acknowledged and is vital to pay money to the donors for...

A Conceptual Framework to incorporate core values in health care and Medical Education system: Targeted review &Thematic Analysis Shima Tabatabai 1.Ph.D.Post-Doctoral Researcher in Medical Education , Shahid Beheshti University Of Medical Sciences, Tehran, Iran. Email:<shtabatabai@yahoo.com> ,shima.tabatabai@sbmu.ac.ir. Orchid ID:0000-0002-7565-6...

Background: Partial adrenalectomy (PA) is an emerging modality typically performed for the treatment of hereditary and sporadic bilateral tumors, to reduce the risk of adrenal failure. In this study, we evaluated the recurrence and functional outcomes after partial and total adrenalectomy (TA). Materials and methods: From March 2005 to July 2018...

We have studied up-to-date knowledge about the clinical feature of the Novel coronavirus pandemic worth consideration by the urologist. PubMed database, the United States centers for disease control and prevention (CDC), and the World Health Organization (WHO) websites were also accessed. A staging system introduced by Siddiqi et al. for the COVID-...

Background: The aim of this paper is to present a synthesis of solutions for post-graduate medical education (PGME) and the health-care system in addressing challenges in relation to women's health. Methods: A critical review was conducted within three themes: women's health status, women's preferences for female physicians, and women in surgery...

Background There is a growing concern about postsurgical outcomes of radical prostatectomy, especially in the younger population and patients with earlier tumor stages. Here, we present our 17 years’ experience of sutureless vesico-urethral alignment after radical prostatectomy with a focus on postoperative functional urinary outcomes. Methods Dat...

Objectives: A lack of donors continues to be a significant problem. Kidney donors with a body mass index ≥ 30 kg/m² are not suitable for laparoscopic donor nephrectomy; however, some studies have suggested that an obese donor could be an appropriate donor with similar surgical outcomes. Here, we report the results of our 10-year experience of lapa...

Abstract Background Kidney transplant improves patients’ survival and quality of life. Worldwide, concern about the equality of access to the renal transplant wait-list is increasing. In Iran, patients have the choice to be placed on either the living or deceased-donor transplant wait-list. Methods This was a prospective study performed on 416 kidn...

Purpose: To evaluate the evidence that could help health system policy makers to approach the preference for same-gender urologists. Methods: We performed this systematic narrative review according to the PRISMA guidelines. We searched MEDLINE, Web of science, EMBASE, CINAHL and Google Scholar for articles focused on the preference for patient-urol...

Purpose: To evaluate the evidence that could help health system policy makers to approach the preference for same-gender urologists. Methods: We performed this systematic narrative review according to the PRISMA guidelines. We searched MEDLINE, Web of science, EMBASE, CINAHL and Google Scholar for articles focused on the preference for patient-u...

Purpose: To evaluate the feasibility and potential efficacy of nanocurcumin supplementation in patients with localized muscle-invasive bladder cancer (MIBC) undergoing induction chemotherapy. Materials and methods: In this double-blind, placebo-controlled trial, 26 MIBC patients were randomized to receive either nanocurcumin (180 mg/day) or plac...

Purpose: The role of laparoscopic pyelolithotomy in the management of renal stones is evolving. One of the challenges in LPL for renal stones are patients with intrarenal pelvis. Here we present our experience with laparoscopic pyelolithotomy for the management of renal stones with intrarenal pelvis anatomy. Materials and methods: Patients candi...

Purpose: Laparoscopic adrenalectomy (LAD) is considered the gold standard surgical method for resecting adrenal tumors. To date, only few small studies have investigated the safety of clipless laparoscopic adrenalectomy in which the adrenal vessels were controlled by the LigaSure system or bipolar coagulation. The aim of the present study was to e...

Purpose: The ureteric stent can be attached to the Foley catheter in kidney transplantation to exclude the cystoscopy for its removal. It is rarely practiced in renal transplantation. There has been no randomized trial to evaluate the outcome of this procedure on the major urologic complications. Materials and methods: One hundred sixty-three ki...

Objective: To determine disease-related predictors for the occurrence of prostate specific antigen (PSA) failure in Iranian prostate cancer patients who underwent radical prostatectomy. Methods: In this cohort study, we enrolled eligible patients with prostate cancer who underwent radical prostatectomy at our center between 2001 and 2018. The pr...

Kidney transplant has been the standard-of-care treatment for patients with end-stage renal disease for many years. To expand the acceptance and care of complicated situations in patients with end-stage renal disease, transplant teams should be ready to find innovative solutions to prevent and manage pretransplant, intraoperative, and posttransplan...

Objectives To evaluate the safety and efficacy of transperitoneal laparoscopic pyelolithotomy in renal stone cases with previous renal surgeries. Patients and methods In this prospective study, 190 consecutive patients with renal stones, who were candidates for transperitoneal laparoscopic pyelolithotomy, were enrolled. The patients were divided i...

Quantitative Achievements in Clinical Postgraduate Medical Education Over Last 4 Decades in I.R.IRAN <http://ijhp.ir/article-1-220-en.html> Background: Following the Islamic revolution in 1979, great advances have been made in Clinical Postgraduate Medical Education. Despite the significant achievements, there has been no comprehensive documentatio...

Background and Aim: The commitment of community-based medical education system are moving towards the ideals of the health system upstream documents, providing ethical and community-based health services and implementing the community ethical values and celestial belief in medical science education. The basic Iranian-Islamic Model of progress devel...

Purpose: We retrospectively reviewed the perioperative outcomes of mini-laparoscopic procedure in the treatment of ureteropelvic junction obstruction (UPJO) in children and adults. Methods: From August 2009 to March 2017, 229 patients referred to our center to repair UPJO by mini-laparoscopic operation. In 203 cases, dismembered pyeloplasty was ac...

Multifocal synchronous renal cell carcinoma in the functioning allograft is a rare disease; there is no consensus regarding its treatment, and few cases have been reported. In isolated masses, some authorities advocate graft nephrectomy, and some recommend partial nephrectomy. To our knowledge, we describe the first experience of nephron-sparing su...

Objectives: It is usually assumed that an active livingdonor transplant program inhibits the growth of a deceased-donor kidney transplant program. In our 33-year experience, we found the contrary to be true. Materials and methods: From 1984 until 2017, we performed a total of 4966 kidney transplant procedures. All cases were registered through t...

Objectives: In this randomized controlled trial, our aim was to compare bipolar cautery of lymphatic vessels with standard silk-tie ligation in renal transplant procedures for prevention of lymphocele formation. Materials and methods: Sixty end-stage renal disease patients were enrolled in a prospective randomized controlled trial. The mean age...

Background: A systematic analysis of the evidence regarding oncological, perioperative and postoperative outcomes of open nephroureterectomy (ONU), laparoscopic nephroureterectomy (LNU), and hand-assisted laparoscopic nephroureterectomy (HALNU) was designed. Methods: The summarized data were abstracted from 52 original research articles represen...

For centuries, stone disease has been a common health problem – in fact, one of the first surgeries performed on humans was for stones – and traditional open surgery was utilized to manage the problems it caused.¹ Stone disease is still common today, but the pattern of practice in stone management has undergone a revolution in the last few decades....

Stone disease has been a great challenge for surgeons through history and in fact one of the first surgeries performed in human has been for stone. For centuries stone disease has been a common health problem and traditional open surgery has been practiced to manage problems caused for human by urinary stones [1]. Today, stone disease is still comm...

Background: This systematic review and meta-analysis was designed to evaluate the post-operative outcomes between tubeless and standard percutaneous nephrolithotomy (PCNL) among children. Methods: Literature searches were performed following the Cochrane guidelines. We conducted a systematic review and meta-analysis that included three trials in...

Celestial teachings are comprehensive guidances for reaching to the ideal integrity of human being. Of the most considerable and important axes in celestial teachings are family and population. Promoting family health, increasing fertility rate, balance, and youth of the population is the countries policy. Explaining the ideal pattern of family hea...

ACTH-independent Cushing's syndrome is an uncommon disorder in children. While laparoscopic adrenalectomy is well-established in adults, it is rarely used in infants and is associated with some concerns. A seven-month infant was referred to our hospital due to progressive signs and symptoms of Cushing's syndrome. Laboratory data confirmed ACTH-inde...

Management of complete staghorn kidney stones is a urological challenge. Due to the high recurrence rates, complete stone clearance is of crucial importance in staghorn stones. Anatrophic nehrolithotomy is an option in cases where, less invasive procedures such as percutaneous nephrolithotomy (PCNL) and extracorporeal shock wave lithotripsy (SWL) c...

AIM To compare the outcomes between related and unrelated kidney transplantations. METHODS Literature searches were performed following the Cochrane guidelines. We conducted a systematic review and a meta-analysis, which included 12 trials that investigated outcomes including the long-term (ten years), mid-term (one to five years), and short-term...

Abstract. Tumor protein 53 (TP53), a tumor suppressor gene, is a vital cellular cancer suppressor in multicellular organisms. Murine double minute‑2 (MDM2) is an oncoprotein that inhibits TP53 activity. A number of studies have examined the association of TP53 and MDM2 polymorphisms with the risk of common forms of cancer, but the findings remain i...

Background The shortage of cadaveric kidney donors has prompted transplant teams to expanding the donor selection criteria. The usage of pediatric cadaveric kidneys is one of those expanded criteria. But the main concern is the probability of hyperfiltration syndrome due to small renal mass of pediatric donors. Objective To compare the graft and p...

Purpose: The aim of this single center study was to determine if the outcomes after kidney transplant were influenced by side of kidney donation and/or side of implantation (left versus right).Materials and methods: All kidney transplantations in our department from June 1993 to November 2015 were included. Data was prospectively gathered and used...

Purpose: Partial nephrectomy is the gold standard treatment for small kidney masses. Data on the comparison oflaparoscopic (LPN) versus open partial nephrectomy (OPN) are based on retrospective studies. Thus, we plannedto compare these two techniques in a prospective trial. Materials and methods: The study population consisted of patients over 1...

Background: Extracorporeal shock wave lithotripsy (ESWL) is an important tool for the management of urolithiasis. The effects of shockwaves on tissues are established. The aim of this meta-analysis is to evaluate the microscopic semen characteristics of young men before and after ESWL treatment for lower ureteral calculi. Methods: Literature sea...

Objectives: Our objective was to evaluate the effect of kidney graft weight-to-recipient body weight ratio as a nonimmune factor that may affect long-term graft function. Materials and methods: We retrospectively collected data from 2531 living donor kidney transplant procedures performed between 1994 and 2010 at Shahid Labbafinejad Medical Cent...

PURPOSE:Treatment of pediatric urolithiasis is still on debate. This study was designed to evaluate the safety and efficacy of laparoscopic pyelolithotomy in five children less than two years old. MATERIALS AND METHODS: Five children (less than two years old) with large kidney stones underwent laparoscopic pyelolithotomy. All patients underwent lap...

Objectives: Inserting a double J stent during kidney transplant has reduced the rate of urologic complications. Traditionally, a double J stent is removed via endoscopic intervention. Here, we assessed the safety and efficacy of a nonoperative method for double J stent removal. Materials and methods: Our study group included 200 consecutive pati...

Lysosome associated protein transmembrane 4 beta (LAPTM4B) is an oncogene associated with many human Cancers. In the present study we aimed to examine the possible association between LAPTM4B polymorphism and risk of prostate cancer (PCa) in an Iranian population. This case control study was done on 168 PCa patients and 176 benign prostatic hyperpl...

Promoting Post Graduate Medical Education in Iran:Challenges & Solutions; a Qualitative study Background & Purpose: Promotion of Postgraduate Medical Education (PGME) is constantly one of the main concerns’ for medical education policy makers because of the key role of residents and graduated specialists/subspecialists in health care system. This...

Objectives: The objective of this study was to investigate the long-term outcomes of inverted kidney transplant, an alternative easy and safe technique to overcome difficulties associated with short right renal vein anastomosis after laparoscopic donor nephrectomy. Materials and methods: Seventy-nine laparoscopic donor nephrectomies and intentio...

ABSTARCT Background: The research focus is on the study of post graduate Medical education (Specialty/subspecialty training) achievements in I.R.Iran, emphasizing on the importance of these evidence in growth trends analysis and future studies for purposeful development of postgraduate medical education. Methods: The present study was a National pr...

This study was conducted to compare safety, efficacy and cosmetic outcome between standard laparoscopic live donor nephrectomy (sLDN) and mini-laparoscopic donor nephrectomy (mLDN) in a randomized clinical trial. From March 2012 to June 2013, 100 consecutive kidney donors were randomly assigned to two equal groups for laparoscopic donor nephrectomy...

Iran’s Postgraduate Medical Education Achievements over Last 35 Years

Aims: This article provides important information on Iran clinical postgraduate education progresses over the last 35 years. This historical study focus is on post graduate education quantitative achievements and growth of admitted residents and graduated specialist and subspecialists and fellowships by gender since 1979 after the revolution in Ira...

Over the past 35 years Iran had significant quantitative progress in postgraduate medical education; and growth in specialist's physician workforce supply. Health and medical education policy makers have struggled with many issues related to physician supply, such as determining the sufficient number of physicians workforce and the appropriate numb...

Objective To evaluate safety, efficacy, and cosmetic results after mini laparoscopic (mL) pyeloplasty and standard (sL) pyeloplasty in children younger than 1 year of age with ureteropelvic junction obstruction (UPJO). Materials and methods From August 2009 to March 2011, 20 sL pyeloplasties were performed in pediatric patients younger than 1 year...

Objectives: To evaluate outcomes and complications with pediatric living-donor kidney transplant, mostly performed with laparoscopic donor nephrectomy. Materials and methods: In the 25 years between February 1987 and December 2012, there were 493 children aged ≤ 17 years who received a kidney transplant. Demographic characteristics, graft and pa...

There is a global crisis constituting severe shortages of health professionals and mal-distribution of health human resources. There are some important mega trends that affect this challenge: ... Conclusion This national project is an ongoing process and will continue to develop health workforce future studies incorporating data and methodology imp...

Background and Objectives: Major vascular injury is the most devastating complication of laparoscopy, occurring most commonly during the laparoscopic entry phase. Our goal is to report our experience with major vascular injury during laparoscopic entry with closed- and open-access techniques in urologic procedures. Methods: All 5347 patients who u...

Purpose: The research focus is on the study of clinical post graduate education achievements since 1979, and considering the importance of future studies and regional foresight in purposeful development of postgraduate medical education. Method: The present study was a National practical Study for describing Iran significant post graduate medical e...

Purpose: Laparoscopy is the gold standard approach for management of some adrenal masses in adult cases. Still there have not been many findings in case of children. We present our experience with clipless laparoscopic adrenalectomy in pediatric cases for the first time. Materials and methods: From January 2007 to January 2011, thirteen laparosc...

Purpose: To present the safety and surgical outcomes of the initial series of mini-laparoscopic live donor nephrectomy and graft outcomes in related recipients. Materials and methods: From January 2012 through July 2012, fifty patients underwent minilaparoscopic live donor nephrectomy. Two 3.5 mm trocars were inserted above and lateral to the um...

Purpose: The study focus is on the quantitative achievements in urology education and growth trends in urologic surgical workforce and fellowships by gender since 1979. Materials and methods: This comprehensive national quantitative study was performed in Iranian Academy of medical science. The first hand data gathered from The Iran Specialty Tr...

Objective: This study evaluated the outcomes of laparoscopic donor nephrectomy (LDN) and proposed modifications for kidney donation surgery. From February 1997 to February 2011, 1510 LDNs were performed. Patients and methods: Surgical modifications included a modified open access technique for entry into the abdominal cavity, using vascular clip...

To evaluate efficacy of modified retroperitoneal lymph node dissection (RPLND) in the management of patients with pathological stage (PS) I non-seminomatous germ cell testicular tumor (NSGCT) in a retrospective study. Between April 2002 and April 2012, 55 patients with clinical stage (CS) I NSGCT had undergone modified RPLND according to Sloan-Kett...

While most renal and ureteral stones can be efficiently managed using endourologic techniques, the use of laparoscopy for the management of urolithiasis is increasing. The application of laparoscopy for stone removal will further reduce the need for open stone surgery. Laparoscopic ureterolithotomy, pyelolithotomy, and anatrophic nephrolithotomy ar...

Background: Management of staghorn renal stones is still challenging. We present our experience with laparoscopic anatrophic nephrolithotomy as an alternative option for management of staghorn renal calculi. Patients and methods: Twenty-four patients with staghorn renal calculi underwent 25 laparoscopic anatrophic nephrolithtomy procedures. Char...

Background: Defective DNA repair capacity caused by inherited polymorphisms could be associated with cancer susceptibility. One of the major repair pathways is Nucleotide Excision Repair (NER). We investigated Xeroderma Pigmentosum complementation group C (XPC) polymorphisms (Lys939Gln, PAT) with the risk of prostate cancer. Methods: 154 confirm...

To describe mini-laparoscopic donor nephrectomy (MLDN). In this novel approach, we used 3.5 mm trocars in usually visible parts of the abdomen. A 27-year-old man underwent MLDN. The first trocar was placed transumblically, which is used for videoscope. Two 3.5 mm trocars were placed above and lateral to the umbilicus and were used for grasping and...