
Nasser AliAl Baha University · Department of Pharmacognosy, Faculty of clinical Pharmacy
Nasser Ali
Dr. rer. nat.
About
84
Publications
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Introduction
Name: Nasser Abdullah Awadh Ali
Present Profession: Head of Department of Pharmacognosy, Faculty of Clinical Pharmacy, Albaha University, Albaha, KSA
e-mail; alinasser9678@yahoo.com,
Academic Status:: Professor of Pharmacognosy and Phytochemistry
Additional affiliations
September 2002 - July 2006
July 2010 - September 2010
January 2001 - December 2012
Education
September 1992 - July 1996
EMA-University, Greifswald Germany
Field of study
September 1982 - July 1983
EMA-University
Field of study
October 1978 - July 1982
EMA-University
Field of study
Publications
Publications (84)
Crotalaria burhia (Family: Fabaceae) is an important medicinal plant widely distributed in arid parts of the world, including Pakistan, India, and Afghanistan. This plant has enormous ethnobotanical values and is used to treat various common ailments such as swelling, infections, cancer, hydrophobia, pain and skin diseases. Moreover, it is also uti...
In the present research, oleuropein (OLE) contents from two Saudi Arabian wild olive trees (Olea europaea L.) leaves (O1 and O2), were collected from two nearby geographical sites differing in altitudes, and were determined via UHPLC-MS analysis. Moreover, total bioactive contents, antioxidant, and cytotoxicity (against MCF-7 and MDA-MB-231 cells)...
Consuming modern medicines with traditional herbs to treat and prevent diseases or even maintain health and well-being is common in different countries. Despite the high prevalence of this activity in Yemen, there is neither proper regulation that controls the production, standardization, quality control and use nor an appropriate system for herbal...
The chemical composition of the hydrodistilled leaf essential oil from Plectranthus tenuiflorus growing wild in Yemen was determined by GC-MS-analysis and bioautographic assay was used to evaluate the anti-phytofungal activity of the oil against Cladosporium cucumerinum. Thirty-eight components were identified in the essential oil representing 76.2...
Background: There is an urgent need to find new xanthine oxidase (XO) inhibitors with few adverse effects and potent activity, not only for treating gout but also to fight diseases associated with XO activity such as cardiovascular diseases, cancer, diabetes, and obesity. Objective: Screening of Saudi medicinal plants for XO inhibitory activity, to...
Bioassay-guided isolation protocol was performed on petroleum
ether extract of Peperomia blanda (Jacq.) Kunth using column chromatographic
techniques. Five compounds were isolated and their structures were elucidated
via one-dimensional (1D) and two-dimensional (2D) NMR, gas chromatography
mass sectroscopy (GCMS), liquid chromatography mass spectro...
Limonium socotranum and Peperomia blanda are used in ethnomedicine to treat several diseases, such as infection, cancer, and inflammation. P. blanda (family: Piperaceae) is from the genus Peperomia, and mostly found in Madagascar, Yemen, USA to South America, while L. socotranum (family: Plumbaginaceae) from the genus Limonium and this species is f...
Background
Peperomia belongs to the family of Piperaceae. It has different uses in folk medicine and contains rare compounds that have led to increased interest in this genus. Peperomia blanda (Jacq.) Kunth is used as an injury disinfectant by Yemeni people. In addition, the majority of Yemen’s population still depend on the traditional remedy for...
Dataset 1
Crystal deposotion files.
Background
Local natural medicinal resource knowledge is important to define and elaborate usage of herbs, in systematic and organized manner. Until recently, there has been little scientifically written document regarding the traditional uses of medicinal plants in Al Bahah region.
Objective
This pilot study aims to collect the ethnobotanical inf...
Onopordum acanthium (Scotch thistle) belong to Asteraceae (Compositae). O. acanthium is a flowering biennial plant native to Europe and Western Asia with coarse spiny leaves 20-50 cm in width with conspicuous and spiny-winged stems. We have previously reported pro-apoptotic and cytotoxic effect of Onopordum acanthium crude extract against glioblast...
The leaf essential oil of Otostegia fruticosa subsp. schimperi (Lamiaceae) was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry (GC-MS). The major components in the leaf oil were τ-cadinol (9.3%), β-caryophyllene (8.8%), and bornyl formate (5.2%) as well as two unidentified diterpenoids (12.7% and 9.4%, respectiv...
The chemical composition of the hydrodistilled aerial parts of essential oil from Lavandula pubescens Decne. collected from Imran in Yemen was determined by GC-MS analysis, and its cytotoxic, xan-thine oxidase inhibitory, antiradical and antimicrobial activities were evaluated. The main compounds were carvacrol (72.7 %), carvacrol methyl ether (7.0...
Background: Ocimum forskolei and Teucrium yemense (Lamiaceae) are used in traditional medicine in Yemen. Methods: The chemical composition, antimicrobial, antioxidant and cytotoxic activities of the essential oils isolated from the leaves of Ocimum forskolei Benth. (EOOF) and two different populations of Teucrium yemense Deflers., one collected fro...
Abstract: Rosemary (Rosmarinus officinalis L.) is a popular herb in cooking, traditional healing, and
aromatherapy. The essential oils of R. officinalis were obtained from plants growing in Victoria
(Australia), Alabama (USA), Western Cape (South Africa), Kenya, Nepal, and Yemen. Chemical
compositions of the rosemary oils were analyzed by gas chrom...
The Saudi medicinal plant, Juniperus procera Hochst. ex Endl. has been used traditionally for wound healing, rheumatism, and gout. Different organic extracts of J. procera leaves collected from Albaha were investigated for in vitro antimicrobial, antiradical and xanthine oxidase (XO) inhibitory activity. At a concentration of 4 mg /well, chloroform...
The hydrodistilled essential oil obtained from the dried leaves of Myrtus communis, collected in Yemen, was analysed by GC–MS. Forty-one compounds were identified, representing 96.3% of the total oil. The major constituents of essential oil were oxygenated monoterpenoids (87.1%), linalool (29.1%), 1,8-cineole (18.4%), α-terpineol (10.8%), geraniol...
Defatted methanol extract obtained from Prosopis juliflora collected
from Yemen was investigated for antimicrobial activity against
different strains of bacteria and Candida albicans which were known
to cause different types of skin infections. The minimum inhibitory
concentration (MICs) was determined by microdilution assay. Defatted
methanol extr...
Lavandula pubescens Decne. is one of five Lavandula species growing wild in Yemen. The plant is used in Yemeni traditional medicine, and the essential oil tends to be rich in carvacrol. In this work, L. pubescens was collected from eight different locations in Yemen, the essential oils obtained by hydrodistillation, and the oils analyzed by gas chr...
Defatted methanol extract obtained from Prosopis juliflora collected from Yemen was investigated for antimicrobial activity against different strains of bacteria and Candida albicans which were known to cause different types of skin infections. The minimum inhibitory concentration (MICs) was determined by microdilution assay. Defatted methanol extr...
Numerous plants are known to exhibit considerable biological activities in the fields of medicine and agriculture, yet access to their active ingredients is often complicated, cumbersome and expensive. As a consequence, many plants harbouring potential drugs or green phyto-protectants go largely unnoticed, especially in poorer countries which, at t...
Hydnora abyssinica A.Br. (Hydnoraceae), a holoparasitic herb, is for the first time recorded for Abyan governorate of South Yemen. Flowers of this species were studied for their ethnobotanical, biological and chemical properties for the first time. In South Yemen, they are traditionally used as wild food and to cure stomach diseases, gastric ulcer...
Hydnora abyssinica A.Br. (Hydnoraceae), a holoparasitic herb, is for the first time recorded for Abyan governorate of South Yemen. Flowers of this species were studied for their ethnobotanical, biological and chemical properties for the first time. In South Yemen, they are traditionally used as wild food and to cure stomach diseases, gastric ulcer...
Five methanol extracts obtained from five plant species selected according ethnobotanical data were screened for their antiprotozoal activity against Plasmodium falciparum, Leishmania infantum, Trypanosoma cruzi and Trypanosoma brucei. Cytotoxicity was evaluated on MRC-5 cells. Withania somnifera methanol extract showed low activity against P. falc...
The aerial parts of Ocimum basilicum L. were collected from four different geographical locations, Sindhuli and Biratnagar (Nepal), Chormaghzak village (Tajikistan), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 179 essential oil compositions rev...
The aerial parts of Lantana camara L. were collected from three different geographical locations: Artemisa (Cuba), Biratnagar (Nepal), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography - mass spectrometry. A cluster analysis of 39 L. camara essential oil compositions revealed eight major ch...
Aim/Background: The development of resistance to synthetic drugs by target organisms is a major challenge
facing medicine, yet locked within plants are phytochemicals used in herbal medicine (especially in the
Arabian Peninsula) that may find application in this regard. In pursuit of unlocking these “hidden treasures,”
the methanol extracts of leav...
The chemical composition of the hydrodistilled leaf essential oil from Chenopodium ambrosioides L. growing wild in Yemen was determined by GC-MS analysis, and its cytotoxic, and general antioxidant potential were evaluated. Major compounds of C. ambrosioides oil were ascaridole (54.2%), isoascaridole (27.7%) and p-cymene (8.1%). At concentrations o...
The chemical composition of the essential oil obtained from the flowers of Pulicaria jaubertii Gamal-Eldin (syn. Pulicaria orientalis Jaub.) was analyzed by GC-MS. The oil of P. jaubertii oil was strongly dominated by p-Menth-6-en-2-one (carvotanacetone) (93.5%) followed by chrysanthenone (0.9 %) and borneol (0.7 %). The antimicrobial activity of t...
Sixteen methanolic extracts obtained from thirteen plant species, selected either from ethnobotanical or chemotaxonomical data, were screened for their antileishmanial activity against Leishmania amazonensis. The cytotoxic activity against normal peritoneal macrophages from normal BALB/c mice was also determined. Eight extracts had IC50 values rang...
Yemen is a small country located in the southwestern part of the Arabian Peninsula. Yemen’s coastal lowlands, eastern plateau, and deserts give it a diverse topography, which along with climatic factors make it opulent in flora. Despite the introduction of Western medicinal system during the middle of the twentieth century, herbal medicine still pl...
The essential oils from the aerial parts of Artemisia abyssinica, collected from three different locations
in Yemen, were obtained by hydrodistillation and analyzed by gas chromatography – mass
spectrometry. The essential oil from Taiz was dominated by davanone (49.4%) and camphor (29.6%),
while samples from Sana’a and Alhodiadah had camphor as the...
A total of fifty different extracts from eighteen endemic Soqotran
medicinal plants belonging to twelve plant families were screened for
their antioxidant activity, using the DPPH free radical scavenger assay
and their antiphytofungal activity against the phytopathogenic fungus
Cladosporium cucumerinum, using a microbioassay on TLC plates. Of
the e...
Hydrodistilled essential oils from aerial parts of Artemisia abyssinica
Sch.Bip. ex A. Rich, and Artemisia arborescens L. growing in Yemen
were screened for their cytotoxic and antiphytofungal properties as
well as their chemical compositions. Twenty-seven components were
identified in the essential oils and the main components of these
species wer...
The present work aims to evaluate the antimicrobial activity of essential oils of two different places of similar Lavandulla pubescens (Taiz and Ibb). The antimicrobial properties of essential oils obtained from L. pubescens (Taiz) and L. pubescens (Ibb) were examined. To evaluate the in vitro antimicrobial activities of these tow aromatic extracts...
Hydro distilled essential oil obtained from Thymus laevigatus collected
from Yemen was investigated for antimicrobial activity against
different strains of bacteria and Candida albicans which were known
to cause different types of skin infections. The minimum inhibitory
concentration(MICs) were determined by micro dilution assay.
Essential oil of T...
The essential oil from the leaves of Tagetes minuta L., growing wild in Yemen, was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. A total of 28 compounds were identified representing 74.2% of total oil composition. Major components of the essential oil were (Z)-ocimenone (15.9%), (E)-ocimenone (34.8%), (Z)-beta-...
The aim of this study was to investigate and compare Mirabilis jalab L. extracts obtained in Ultrasonic condition with different water/methanol and water/ethanol extraction mixture acidified with 0.1% HCl. The extracts were analyzed for monomeric anthocyanins contents and antioxidant activities. The highest anthocyanins content (3197.8 mg/L) and th...
Basil is a well-known aromatic plant used in the traditional medicine in many Asian, African, and South American countries for treatment of diseases. The therapeutic activity of basil is partly due to the presence of
essential oils which possess a wide spectrum of pharmacological effects. In the present review, efforts have been made to sum up diff...
The leaf essential oil of Tarchonanthuscamphoratus(Asteraceae) was obtained by hydrodistillation and analyzed by GC–MS. Fifty-six components were characterized, representing 94.2% of the total oil with oxygenated monoterpenes (48.3%) and oxygenated sesquiterpenes (32.7%) as the major groups. The
principal constituents were identified as endo-fencho...
The leaf essential oil of Tarchonanthuscamphoratus(Asteraceae) was obtained by hydrodistillation and analyzed by GC–MS. Fifty-six components were characterized, representing 94.2% of the total oil with oxygenated monoterpenes (48.3%) and oxygenated sesquiterpenes (32.7%) as the major groups. The
principal constituents were identified as endo-fencho...
The chemical composition, antimicrobial, antioxidant and cytotoxic activities of the essential oils isolated from the leaves of Plectranthus cylindraceus
Hoechst. ex. Benth. (EOPC) and Meriandra benghalensis (Roxb.) Benth. (EOMB) were investigated. Sixteen compounds were identified in P. cylindraceus oil
representing 94.5% of the oil content with t...
The chemical composition of the essential oil obtained from the leaves of Pulicaria undulata Gamal Ed Din (syn P. orientalis sensu
Schwartz and P. jaubertii Gamal Ed Din) was analyzed by GC-MS. Major compounds of P. undulata oil were the oxygenated
monoterpenenes, carvotanacetone (91.4%) and 2,5-dimethoxy-p-cymene (2.6.%). The antimicrobial activit...
A series of prevailing prenylated furanocoumarins from leaves of Dorstenia gigas and Dorstenia foetida (Moraceae) were investigated by liquid chromatography/electrospray tandem mass spectrometry. The mass spectral behavior of the furanocoumarins under positive ion electrospray conditions is discussed using both an ion trap and a triple quadrupole s...
The chemical composition of the hydrodistilled leaf essential oil from Pulicaria stephanocarpa Balf. Fil was determined by GC-MS analysis, and its antimicrobial, antioxidant and anticholinesterase (AChE) activities were evaluated. Eighty-three compounds were identified representing 97.2% of the total oil. (E)-Caryophyllene 13.4%, (E)-nerolidol 8.5%...
A series of prevailing prenylated furanocoumarins from leaves of Dorstenia gigas and Dorstenia foetida (Moraceae) were investigated by liquidchromatography/electrospray tandem mass spectrometry. The mass spectral behavior of the furanocoumarins under positive ion electrospray conditions is discussed using both an ion trap and a triple quadrupole sy...
In this study, we report the preliminary data on the chemical composition of Yemeni Schinus molle L. volatile oil obtained by supercritical extraction with carbon dioxide (40°C and 90 bar), SFE, and by hydrodistillation (HD). The composition of the volatile oil has been analysed by GC and GC-MS. The content of the major constituents in the oils fro...
A total of 30 chloroform and methanol extracts from the following endemic Soqotran plants Acridocarpus socotranus Olive, Boswellia socotranao Balf.fil, Boswellia elongata Balf. fil., Caralluma socotrana N. Br, Cephalocroton socotranus Balf.f, Croton socotranus Balf. fil.., Dendrosicycos socotrana Balf.f., Dorstenia gigas Schweinf. ex Balf. fil., Eu...
Fractionation of the stem extract from Catha edulis resulted in the isolation of two known aglycones dihydroquercetin, taxifolin and dihydromyrecitin, ampelopzin.. Fractionation of leaf extract resulted in isolation of 4 flavonoid glycosides dihydroquecetin –rhamnoside astilbin; dihydromyricetin 3-O-rhamnoside; myricetin-3-O-L-rhamnoside, myricitri...
Chemical composition of the essential oil of Lavandula pubescens Decine, (Lamiaceae) collected from Arrojom locality- Mahweet province, Yemen was studied by gas-chromatography mass spectrometry. Thirteen constituents were identified in the oil distilled from leaves, of which carvacrol (70.0%), caryophyllene oxide (5.5%), -copaene (3.7%), -bisabol...
Loranthus regularis Steud. ex Sprague (Loranthaceae) aerial part is widely used for medicinal purposes. Toevaluate its anti-inflammatory, antinociceptive and antipyretic activities, two concentrations of theextract and its fractions were tested in carrageenan-induced rat paw oedema, hot-plate test model in mice and brewer’s yeast-induced pyrexia in...
This article reports the composition of the essential oil from the leaves of Stachys yemenensis. The essential oil was extracted by supercritical CO₂ (90 bar; 40 °C) and its chemical composition was determined by gas chromatography and gas chromatography-mass spectrometry. The major components of the sample were α-phellandrene (13.9%), β-phellandre...
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The essential oil extracted from the oleogum resin of the Yemeni Commiphora habessinica (Berg.) Engl. was analyzed by gas chromatography-mass spectrometry (GC-MS) and 13 constituents were identified. The major constituents were β-elemene (32.1 %), α-selinene (18.9 %), cadina-1,4-diene (7.5 %), germacrene B (3.6 %), α-copaene (3.5 %), t-muurolol (3....
One of author’s name in this article has been printed wrongly. The name of Ludger Wessjohan should bewritten as Ludger Wessjohann. The authors apologize for this error.
One of author’s name in this article has been printed wrongly. The name of Ludger Wessjohan should be written as Ludger Wessjohann. The authors apologize for this error.
Chemical composition of the essential oil obtained from the leaves of the
endemic Soqotraen Pulicaria stephanocarpa Balf. Fil. was analyzed by GC-MS.
Sesquiterpenes are the predominant portion of both essential oils. Major
compounds of Pulicaria stephanocarpa oil were -cadinol (42.5%), spathulenol
(22.%), caryophyllene (10.8%), -cadinene (5.4%), ci...
The major constituents of the essential oil obtained by hydrodistillation from the oleogum resin of Commiphora kua Vollesen were identified by GC-MS. Sixteen constituents were detected from the essential oil, which constituted about (90.5%) of the total amount. Major constituents of the oil were �alpha- cadinol (33.0%),gamma, cadinene (22.5%), d-ca...
The chemical composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Teucrium yemense Deflers was determined by GC-MS. Twelve compounds accounting to 77.7% of the total oil were identified. Sesquiterpene hydrocarbons (73.9%) were the predominant portion of the oil with δ-cadinene (34.9%), β-caryophyllene (22.7%), a -h...
A new pyran derivative, 6-hydroxy-2H-pyran-3-carbaldehyde, has been isolated from the methanolic extract of Crinum yemense along with the known alkaloid haemanthamine, benzoic acid and 1,1'-bis(1,1'-carboxyethyl) ether which is isolated from a natural source for the first time. Structure elucidation of these compounds based on spectroscopicevidence...
The chemical composition, antioxidant and anticholinesterase activity of three essential oils (EOs) obtained from the oleogum resin of three endemic Sqotraen Boswellia species, Boswellia socotrana Balf. f, Boswellia ameero Balf. f, and Boswellia elongata Balf. f were determined. GC-MS technique was used for the
analysis of the oils. Oils of B. soco...
The chemical composition, antioxidant and anticholinesterase activity of three essential oils (EOs) obtained from the oleogum resin of three endemic Sqotraen Boswellia species, Boswellia socotrana Balf. f, Boswellia ameero Balf. f, and Boswellia elongata Balf. f were determined. GC-MS technique was used for the analysis of the oils. Oils of B. soco...
Thirty extracts obtained from 10 endemic plant species belonging to 8 plant families used in the traditional medicine in Socotra have been tested for cytotoxic activity against FL-cells. Extracts of Eureiandra balfourii and Commiphora ornifolia showed the strongest activity against FL-cells with IC(50) < 10 microg/ml and 39.3 microg/ml respectively...
Thirty extracts obtained from 10 endemic plant species belonging to 8 plant families used in the traditional medicine in Socotra have been tested for cytotoxic activity against FL-cells. Extracts of Eureiandra balfourii and Commiphora ornifolia showed the strongest activity against FL-cells with IC50 < 10 μg/ml and 39.3 μg/ml respectively.
The purpose of this investigation is to develop a simple method for the assessment of pesticides in Khat leaves, Catha edulis Forsk. (Celastraceae) shrub, chewed by about 60 % of the Yemeni people, producing amphetamine-like psychostimulation. The first procedures involve solid-phase extraction using Adsorbex® RP-C18 and Bakerbond® RP-C18 disposabl...