Naser Safaie

Naser Safaie
Tarbiat Modares University | TMU · Department of Plant Pathology

Prof.(Associate)

About

270
Publications
80,872
Reads
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3,235
Citations
Introduction
I currently work on plant epidemics, plant disease management, and biological control of plant diseases by fungal and bacterial antagonists as well as endophytic fungi. My team and I are working on plant microbiomes to alleviate biotic and abiotic stresses in plants as well as to boost their secondary metabolites.
Additional affiliations
April 2018 - present
Tarbiat Modares University
Position
  • Research Deputy of Faculty of Agriculture
November 2011 - October 2018
Tarbiat Modares University
Position
  • Head of Department
September 1989 - June 1993
Isfahan University of Technology
Position
  • Student
Education
September 1996 - October 2002
Tarbiat Modares University
Field of study
  • Plant Pathology: Mycology and Plant fungal Diseases
September 1993 - June 1996
Shahid Chamran University of Ahvaz
Field of study
  • Plant Pathology
September 1989 - June 1993
Isfahan University of Technology
Field of study
  • Plant Protection

Publications

Publications (270)
Article
Full-text available
Auricularia is one of the most widely distributed macrofungi, regarded as an edible medical mushroom, and is the third largest cultivated mushroom in the world due to its high nutrition and bioactivity properties. This research specifies the taxonomic status of this genus in Iran for the first time. After sample collection during 2017-2018, 19 samp...
Article
Full-text available
Leaf rust is one of the most important diseases and influences the sustainable cultivation of wheat. Therefore, for the first time in Iran, the spatial pattern and temporal progress of this disease were assessed in five wheat cultivars, including Chamran 2, Star, Ofogh, Kavir, and Boolani, with different resistance levels in 2015-16 and 2016-17 cro...
Article
Full-text available
Sterol Biosynthesis Inhibitors (SBIs) are a major class of fungicides used globally. Their widespread application in agriculture raises concerns about potential harm and toxicity to non-target organisms, including humans. To address these concerns, a quantitative structure-toxicity relationship (QSTR) modeling approach has been developed to assess...
Article
Urban forest trees are vital components of urban ecosystems, offering a range of benefits that are essential for improving the livability and sustainability of cities, providing numerous advantages for both the environment and public health. They enhance air quality by filtering pollutants, assist in regulating urban temperatures, and alleviate the...
Article
Full-text available
Rhizobacteria play a crucial role in plant health by providing natural antagonism against soil-borne fungi. The use of rhizobacteria has been viewed as an alternative to the use of chemicals that could be useful for the integrated management of plant diseases and also increase yield in an environmentally friendly manner. However, there is limited u...
Conference Paper
DMIs (Demethylation inhibitors) are a widespread group of antifungal agents targeting sterol biosynthesis in pathogenic fungi [1]. However, the global use of these chemicals in agriculture and medicine may cause potential toxic effects on non-target organisms [2]. Herein, we developed quantitative structure-toxicity relationship (QSTR) models for t...
Article
Full-text available
A total of 1,348 endophytic fungal strains were isolated from Ferula ovina, F. galbaniflua, and F. persica. They included Eurotiales (16 species), Pleosporales (11 species), Botryosphaeriales (1 species), Cladosporiales (2 species), Helotiales (6 species), Hypocreales (31 species), Sordariales (7 species), Glomerellales (2 species), and Polyporales...
Article
Full-text available
Shiitake (Lentinula edodes) is one of the most widely grown and consumed mushroom species worldwide. They are a potential source of food and medicine because they are rich in nutrients and contain various minerals, vitamins, essential macro- and micronutrients, and bioactive compounds. The reuse of agricultural and industrial residues is crucial fr...
Article
Full-text available
Ginger (Zingiber officinale Roscoe.) is a perennial and monocotyledonous medicinal and spice plant, whose rhizome, essential oil and extract are of interest, and this plant has wide uses in various industries. The origin of ginger is Southeast Asia and possibly India. This plant is mainly cultivated as an annual and the rhizome or the underground s...
Article
Full-text available
Populations of urban forest trees have declined in recent decades owing to various threats. The present study focused on the role of biotic agents, as there is a lack of detailed long-term records on diseases affecting urban forest trees. Pathogenic fungi from Acer negundo, A. velutinum, Ailanthus altissima, Albizia julibrissin, Carpinus betulus, C...
Article
Full-text available
Fungal pathogen “Neoscytalidium novaehollandiae” is the causal agent of trunk canker in mulberry trees. Mulberry is considered as most valuable tree for landscaping in Tehran. Here in, for the first time, chitosan nanoparticles (CSNPs) were used to inhibit canker disease causal agent of mulberry. For this purpose, CSNPs were synthesized with a yiel...
Article
Beet curly top disease is one of the most important viral diseases that causes economic damage to the yield of beet crops. The present study aimed to evaluate the effect of treating the Paya cultivar of sugar beet with Bacillus subtilis, Trichoderma harzianum, and Beta-aminobutyric acid (BABA), alone and in combination, on the growth and reaction o...
Article
Full-text available
Apple (Malus domestica Borkh) is one of the most consumed and nutritious fruits. Iran is one of the main producers of the apple in the world. Diplodia bulgarica is the major causal agent of apple tree decline in Iran. Biological control is a nature-friendly approach to plant disease management. Trichoderma zelobreve was isolated from apple trees in...
Book
Full-text available
https://www.frontiersin.org/research-topics/34917/endophytic-fungi-secondary-metabolites-and-plant-biotic-and-abiotic-stress-management/magazine?utm_source=copy_link&utm_medium=social&utm_campaign=rt_magazine_share&utm_content=rt34917
Article
Fungal stem cankers are common and destructive diseases in apple orchards. Cytospora cincta and Neoscytalidium dimidiatum are the apple canker causal agents in Iran. Formulated biocontrol agents of plant diseases are considered alternatives to synthetic pesticides in sustainable agriculture. The results showed that Trichoderma zelobreve T20 strongl...
Article
Full-text available
Endophytes can live inside plant tissues without causing visible symptoms in their hosts (Hardoim et al., 2015). Endophytic fungi have gained remarkable attention as they not only provide novel sources of bioactive secondary metabolites (SMs) that are the backbone of many drugs but can also protect the host plant from biotic and abiotic stresses th...
Article
Full-text available
A collection of Bacillus and Trichoderma isolates from Iran was investigated for the biological control of pear white root rot caused by Rosellinia necatrix . Among the isolates, B. amyloliquefaciens AP4, B. siamensis AP8 and T. harzianum T20a were selected based on their growth inhibition of R. necatrix in dual cultures, as well as by volatiles, d...
Article
Full-text available
Mycoremediation, a subset of bioremediation, is considered an advanced method to eliminate environmental contaminations. To identify tolerant fungi to copper contamination and study the related gene expression, sampling was carried out from the soil of “Sarcheshmeh Copper Mine,” which is one of the biggest open-cast copper mines in the world. A tot...
Article
Zagros forests are the important ecosystem for water and soil protection. Recently, these forests have been affected by extensive die-back associated with drought and pathogens. In this study, an epidemiological approach was adopted to investigate oak die-back in four sites of unexplored Zagros forests of western Iran, Lorestan. The pathogenic agen...
Article
Full-text available
In this study, the antifungal effects of four species of plant essential oils, including Thymus vulgaris, Eucalyptus camaldulensis, Lavandula angustifolia and Cuminum cyminum, were studied on mycelial growth inhibition of F. oxysporum and F. culmorum isolates. The effect of essential oils was carried out in a factorial experiment in a completely ra...
Article
Full-text available
Various Fusarium species are pathogenic groups that cause economic loss (quantitatively and qualitatively) in Allium cepa L., Fusarium species including F. culmorum and F. subglutinans are of great importance in all onion growing areas. Fusarium infection usually starts from the farm and continue throughout the storage and marketing. Fusarium and b...
Article
Fusarium seedling blight is a disease of cereal crops caused by a group of trichothecene producing Fusarium species such as Fusarium graminearum. Control of seedling blight has received less attention than control of Fusarium head blight. Application of chemicals which activate plant defense mechanisms before pathogen attack without environmental s...
Article
Despite the economic losses due to the walnut anthracnose, Ophiognomonia leptostyla is an orphan fungus with respect to genomic resources. In the present study, the transcriptome of Ophiognomonia leptostyla was assembled for the first time. RNA sequencing was conducted for the fungal mycelia grown in a liquid media, and the inoculated leaf samples...
Article
Full-text available
Aims Despite acceptance of beneficial microorganisms as disease management tools, they seldom offered admirable results due to their instability. Here we aimed to develop cost-effective formulations that would enhance the reliability of beneficial microorganism. Methods Experiments were conducted to determine biocontrol effect of two endophyte fun...
Conference Paper
V3 is a geminiviral protein that codes by Curtovirus, Becurtovirus, Capulavirus, Begomovirus , and some unassigned Geminiviruses however, little information about the function of the protein is available, and besides its responsibility in becurtoviruses have not yet been determined. Using silencing suppression assay, we have shown that V3 can suppr...
Presentation
V3 is a geminiviral protein that codes by Curtovirus, Becurtovirus, Capulavirus, Begomovirus , and some unassigned Geminiviruses however, little information about the function of the protein is available, and besides its responsibility in becurtoviruses have not yet been determined. Using silencing suppression assay, we have shown that V3 can suppr...
Article
Full-text available
Auricularia cornea Ehrenb (syn. A. polytricha) is a wood-decaying fungi known as black ear mushroom. Earlike gelatinous fruiting body distinguishes them from other fungi. Industrial wastes have the potential to be used as the basic substrate to produce mushrooms. Therefore, 16 substrate formulations were prepared from different ratios of beech (BS)...
Article
Full-text available
Geminivirus beet curly top Iran virus (BCTIV) is one of the main causal agents of the beet curly top disease in Iran and the newly established Becurtovirus genus type species. Although the biological features of known becurtoviruses are similar to those of curtoviruses, they only share a limited sequence identity, and no information is available on...
Preprint
Full-text available
The geminivirus beet curly top Iran virus (BCTIV) is one of the main causal agents of the beet curly top disease in Iran and the newly established Becurtovirus genus type species. Although the biological features of known becurtoviruses are similar to those of curtoviruses, they only share a limited sequence identity, and no information is availabl...
Conference Paper
Beet Curly top Iran Virus (BCTIV) is a type virus of a newly described genus, Becurtovirus in the family Geminividae and codes for five ORFs that their function of none of them has not experimentally analyzed. Considering that BCTIV is a recombinant virus with Mastrevirus and Curtovirus ancestors and has a unique genome organization, so bioinforma...
Conference Paper
DMIs (Demethylation inhibitors) are a widespread group of antifungal agents targeting sterol biosynthesis in pathogenic fungi [1]. However, the global use of these chemicals in agriculture and medicine may cause potential toxic effects on non-target organisms [2]. Herein, we developed quantitative structure-toxicity relationship (QSTR) models for t...
Conference Paper
DMIs (Demethylation inhibitors) are a widespread group of antifungal agents targeting sterol biosynthesis in pathogenic fungi [1]. However, the global use of these chemicals in agriculture and medicine may cause potential toxic effects on non-target organisms [2]. Herein, we developed quantitative structure toxicity relationship (QSTR) models for t...
Article
Full-text available
Neoscytalidium novaehollandiae is one of the most important pathogens on woody plants which has increasingly been reported as a pathogen in different hosts in recent years. The pine trees are widely cultured in many cities of Iran. In recent years, dieback symptoms were observed on Pinus eldarica trees in Tehran and Qazvin provinces. The aim of thi...
Article
Full-text available
A characteristic trait of plants living in harsh environments is their association with fungal endophytes, which enable them to survive under extreme stress. Abiotic stress resistance in agro-ecosystems, particularly in arid and semi-arid regions, can be increased by inoculating these fungal endophytes on plants other than their original hosts. The...
Article
Full-text available
Due to their protective functions and medicinal effects, phenylethanoid glycosides (PhGs) have received much attention in recent decades. However, the information on their behavior in response to biotic stress is very limited. Also, the diversity of detected PhGs is low in different plants. Thus, the effect of Piriformospora indica culture filtrate...
Article
Full-text available
Stem rot caused by Athelia rolfsii (syn. Sclerotium rolfsii ), is an important disease of peanut in Iran. Soil samples were collected from 15 peanut fields before the 2014 growing season in Guilan province, Iran and the viable sclerotia were counted using the soil-tray technique. The 15 selected fields were also evaluated for disease incidence at t...
Article
Full-text available
The potential of Trichoderma spp. for biocontrol of phytopathogenic fungi has been well documented. In this study, the wild-type isolate of Trichoderma aureoviride (Tv59) was treated with the target dose of 250 Gy as the optimum dose. Twenty-six mutants were preliminarily screened based on better growth rates. In vitro, antagonistic evaluation of t...
Article
Plants synthesize a variety of metabolites in response to biotic elicitors. To comprehend how the digested cell wall of Piriformospora indica affects the response of ROS burst, antioxidant enzymes, amino acids profiling, and phenylpropanoid compounds such as lignans, phenolic acids, and flavonoids in Linum album hairy roots; we accomplished a time-...
Article
Full-text available
To identify apple canker casual agents and evaluate their pathogenicity and virulence in apple production hubs including West Azarbaijan, Isfahan and Tehran provinces; samples were collected from symptomatic apple trees. Pathogenic isolates on the detached branches were identified as Cytospora cincta , Diplodia bulgarica , Neoscytalidium dimidiatum...
Article
Full-text available
Background Developing new pesticides with multi-function may be a suitable strategy to save time and cost and reduce the emergence of resistant strains of pests and pathogens. The organophosphorus derivatives have not been widely used in agriculture as fungicides. In this work, a series of six α-amino phosphonate derivatives were prepared and teste...
Article
Priming of seeds is a simple and low-cost method in agriculture that improves plant growth, crop yield, and manages pathogens. The current study was carried out to determine SA seed priming effect on susceptibility and resistance of two wheat cultivars (Falat and Sumai3) to Fusarium graminearum at the seedling stage. Both the 1 and 2 mM SA-primed s...
Article
Full-text available
Root rot diseases of sugar beet resulted by Rhizoctonia solani, Pythium aphanidermatum can arouse significant losses in sugar beet crops. Simple and accurate statistical techniques are essential to predict sugar beet yield loss as an industrial crop for agricultural management specialists. The objectives of the present study were to compare: (1) th...
Article
Full-text available
Harnessing plant-microbe interactions to advance crop resistance to pathogens could be a keystone in sustainable agriculture. The breeding of crops to maximize yield in intensive agriculture might have led to the loss of traits that are necessary for beneficial plant-soil feedback. In this study, we tested whether the soil microbiome can induce a s...
Article
Full-text available
This study was carried out to assess in vitro biocontrol efficacy of the Trichoderma aureoviride gamma-induced mutants against three soilborne phytopathogens (Fusarium graminearum, Sclerotinia sclerotiorum and Rhizoctonia solani), and apply rep-PCR analysis for resolving the genetic variations of the wild-type and its mutants. Results showed that d...
Article
Full-text available
Progress in next-generation sequencing has played a significant role in ecological studies of microbial populations. These advances have led to a rapid evaluation in metagenomics studies (analysis of DNA of microbial communities without the need to culture). Many statistical and computational tools and metagenomics databases have led to the discove...
Article
Full-text available
Three Trichoderma harzianum isolates, were evaluated for their antagonistic effect on Rosellinia necatrix causal agent of white root rot (WRT). According to in vitro evaluations, T. harzianum T20A isolate showed the most pathogen growth inhibition. The inoculum of T20A isolate was applied to control WRT disease on four commercial apple rootstocks:...
Article
Full-text available
The responses of rhizosphere bacterial communities of Streptomyces (SS14 and IT20 stains) treated-pepper plants following inoculation by Phytophthora capsici (PC) was investigated using Illumina MiSeq sequencing. Distinct modulation of the bacteriome composition was found for PC samples with the highest relative abundance (RA) of Chitinophaga (22 ±...
Article
Full-text available
Fluorescence-activated cell sorting (FACS) as a novel and sensitive technology was used to evaluate the biocontrol efficiency of Bacillus subtilis against Agrobacterium tumefaciens, a very destructive plant pathogen. The combination of two methods of culturing and cell sorting by FACS technology was used to distinguish a rapid and accurate method i...
Article
Full-text available
Fluorescence-activated cell sorting (FACS) as a novel and sensitive technology was used to evaluate the biocontrol efficiency of Bacillus subtilis against Agrobacterium tumefaciens, a very destructive plant pathogen. The combination of two methods of culturing and cell sorting by FACS technology was used to distinguish a rapid and accurate method i...
Article
Full-text available
Plant infections to several pathogens at a same time are expected in nature. In most cases, plant mixed infections with viruses and fungi could result in increased susceptibility in plant host. In the present study, the interaction between turnip mosaic virus or cauliflower mosaic virus with Phoma lingam in canola (Brassica napus L.) was investigat...
Article
Full-text available
Background Paclitaxel is a well-known chemotherapeutic agent widely applied as a therapy for various types of cancers. In vitro culture of Corylus avellana has been named as a promising and low-cost strategy for paclitaxel production. Fungal elicitors have been reported as an impressive strategy for improving paclitaxel biosynthesis in cell suspens...
Article
Abiotic stresses are among the most damaging and ever-increasing threats to crop production worldwide. Utilizing extreme-habitat-adapted symbiotic microorganisms is a well-known strategy to mitigate the destructive effects of abiotic stresses on agricultural products. Here, we show the effects of the inoculation of halotolerant endophytic fungi rec...
Article
Full-text available
Crown gall is one of the most damaging bacterial diseases that caused economic damages. Nowadays special attention has been focused on biological control of plant diseases as an alternative to chemical control in terms of the dangers of pesticides. There was no special research focused on the interaction between Bacillus and Agrobacterium until now...
Article
A series of phosphonic acid and bisphosphoramidate derivatives were synthesized and characterized. The bioactivities against the fungal pathogen Macrophomina phaseolina and human acetylcholinesterase AChE enzyme were studied using QSAR based on multiple linear regression. L17, with (p-Cl–C6H4–NH) (p-Cl–C6H4)C(H)P(O)(OC2H5)2 skeleton, demonstrated a...
Article
Full-text available
ABASTRACT Differential induction of genes in wheat (cv. Chamran) in response to Mycosphaerella graminicola was studied using cDNA-AFLP analysis. The three weeks old wheat seedlings were inoculated by the fungal pathogen, then the samples were collected at six time points (0, 12, 24, 48, 72, 96 hours) after inoculation with pathogen. By comparing th...
Article
Abiotic stresses are among the most damaging and ever-increasing threats to crop production worldwide. Utilizing extreme-habitat-adapted symbiotic microorganisms is a well-known strategy to mitigate the destructive effects of abiotic stresses on agricultural products. Here, we show the effects of the inoculation of halotolerant endophytic fungi rec...
Article
Full-text available
Background: High antagonistic ability of different Trichoderma species against a diverse range of plant pathogenic fungi has led them to be used as a biological fungicide in agriculture. They can also promote plant growth, fertility, resistance to stress, and absorption of nutrients. They are also opportunistic and symbiotic pathogens, which can l...
Article
Fungal endophyte communities are poorly investigated in extreme habitats such as deserts. We used cultivation and Sanger sequencing to investigate the effects of environmental variables on the endo-phytic fungal communities of eight Iranian desert plants. Host species was the main factor shaping the endophyte composition, while soil type additional...
Article
Full-text available
Fungal endophyte communities are poorly investigated in extreme habitats such as deserts. We used cultivation and Sanger sequencing to investigate the effects of environmental variables on the endo-phytic fungal communities of eight Iranian desert plants. Host species was the main factor shaping the endophyte composition, while soil type additional...
Article
Full-text available
Background Sugar beet ( Beta vulgaris subsp. vulgaris ) is an economically important crop that provides nearly one third of the global sugar production. The beet cyst nematode (BCN), Heterodera schachtii , causes major yield losses in sugar beet and other crops worldwide. The most effective and economic approach to control this nematode is growing...
Article
Full-text available
Genus Lentinula comprises some of the most important edible and medicinal fungal species of the world. To compare growth rate of the strains of this genus, samples were collected from different regions of the world including Iran during 2017-2018. Investigation of the growth of 40 strains on two substrates containing malt and wheat straw extracts s...