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Narayanam Srikanth

Narayanam Srikanth
Central Council for Research in Ayurvedic Sciences · MInistry of AYUSH

Research Collaboration on Coronavirus disease (COVID-19) and Network pharmacology

About

754
Publications
600,172
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Introduction
NARYANAM SRIKANTH, DEPUTY DIRECTOR GENERAL, CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES , Ministry of AYUSH, ,Govt. of India. ACADEMICIAN AND RESEARCHER in Ayurveda and related Sciences. FOCUS:Planing,coordination and conduct of in-house and collaborative Research MEMBER. Several National Committees LIFE MEMBER : Several Scientific Societies EDITORIAL BOARD .Scientific Journals EXPERT FACULTY . International and National scientific events AUTHOR. Research papers,Reports,Books
Additional affiliations
August 2016 - present
Central Council for Research in Ayurvedic Sciences
Position
  • Managing Director
January 2006 - August 2016
Central Council for Research in Ayurvedic Sciences
Position
  • Managing Director
Description
  • Research Management- Intramural/extramural and collaborative research (Planning, evaluation, execution coordination, development and monitoring) ,Drug Development ,Clinical Research
March 1999 - January 2006
Central Council for Research in Ayurvedic Sciences
Position
  • Research Officer
Description
  • Research Management-Intramural/extramural and collaborative research (Planning, evaluation, execution coordination, development and monitoring)
Education
April 2004 - June 2004
June 1993 - August 1996
Bangalore University
Field of study
July 1988 - May 1992

Publications

Publications (754)
Article
Abstract BACKGROUND: Although Ayurveda medicine is used to manage bronchial asthma, available evidence relating to its efficacy needs to be generated. To scientifically evaluate the efficacy and safety of Ayurveda interventions, Kantakaryavaleha and Eladi Gutika, a multicenter, prospective, single-arm, open-label clinical study on mild stable bronc...
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Background: During the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the empirical evidence generated on the efficacy of AYUSH-64 in COVID-19. Objective: To document disease characte...
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Background: During the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the empirical evidence generated on the efficacy of AYUSH-64 in COVID-19. Objective: To document disease characteris...
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Many tribal communities living in the forest area deal with emergency cases of snakebite and scorpion sting by using traditional knowledge of medicinal plants. They possess traditional and authentic information gained from their elders about the antidote for poisonous bites. The present study was conducted in the tribal pockets of Shahapur and Jawh...
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Kerala’s first medical oncologist, the erstwhile Dr. CP Mathew, has left a rich legacy in cancer patients' case diaries and medical records. These documents contain valuable information about his attempts to integrate Siddha and Ayurveda treatments to manage cancer. A preliminary examination of these documents compiled over more than four decades g...
Preprint
Background Bronchial asthma (BA) is a significant health problem and harms the quality of life, and better healthcare strategies are still needed for BA. Therefore, the scope of complementary and traditional medicine therapies on this concern must be explored. Thus the present study aimed to determine the efficacy and the safety of Kantakaryavaleha...
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Background: As per Ayurvedic classics, Rasāyana is a term used for unique therapeutic measures intended to improve cognition, memory, physical strength and delay the degenerative processes. Ayush Rasayana A & B are developed from extracts of herbs pertaining rasayana property. Aims & Objectives: To assess the safety and effectiveness of ‘Ayush Rasa...
Article
Cassia tora L. is one of the widely used plants in ethnic and traditional systems of medicine. A popular species in the genus Cassia, its therapeutic effects on ocular system, integumentary system, hepato pancreatic disorders, gastric system have been documented since centuries and demonstrated through pharmacological experiments. The efficacy of t...
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How to cite this article: Jagtap C, Charde V, Kushwaha V, Garewal J, Shakya SK, Kumar V, et al. Preparation of Vetas Ghana (a semisolid form of Salix alba L. stem bark aqueous extract) and its analysis by using high-performance thin-layer chromatography and liquid chromatography-mass spectrometry. J Drug Res Ayurvedic Sci 2021;6:239-47. This is an...
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Medicinal plants efficacy for various activities, depends on the nature of primary, secondary metabolites and presence of its degree of quantity. The concentrations of secondary metabolites play a vital role for medicinal properties. The amount of secondary metabolites directly related with the growth of the herbs or plants, certainly depends on th...
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INTRODUCTION: Ayurvedic treatments are in use to treat Diabetes Mellitus (DM), either as a standalone treatment or as an adjunct to conventional care. There is need for a comprehensive assessment of the efficacy and safety of Ayurvedic interventions in DM through a systematic review. Therefore present work is planned to create quality based evidenc...
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The present research article proposes a conservative approach for the Desmodium gangeticum by using small branches instead of roots because the plant has many important chemical constituents that show different medicinal activity, so the plant’s consumption is high. We studied here comparative preliminary phytochemical screening test and physicoche...
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Background Patients with gout frequently use complementary and alternative medicines including Ayurveda medications and treatment procedures and hence it is important to determine their safety and e cacy. Objectives A systematic review of the published clinical data in view of safety and effectiveness of Ayurvedic treatment protocols in gout viz-a-...
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BACKGROUND: Viral pandemics/epidemics are emerging as one of the biggest challenge for medical fraternity and health-care policy makers. This is high time to explore traditional medicine systems such as Ayurveda, wherein measures such as Dincharya (daily regimen), Ritucharya (seasonal regimen), Sadvritta (good conduct/behavior), and Rasayana (rejuv...
Article
An Ayurvedic polyherbal formulation (Ayush-64) was repurposed for use in mild to moderate COVID-19 cases based on the supportive evidence obtained from a pilot study on its effect on Influenza like illness (ILI) and molecular docking study which revealed that several compounds isolated from Ayush-64 demonstrated antiviral activity. The study aims a...
Article
A new, simple, selective, sensitive, precise, and robust high-performance thin-layer chromatography (HPTLC) method for the simultaneous quantification of 6-gingerol, guggulsterone E, and guggulsterone Z in coded formulation AYUSH SG-5 (for rheumatoid arthritis) was developed and validated. Analysis of 6-gingerol, guggulsterone E, and guggulsterone...
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Background Conjunctivitis is the inflammation of the conjunctiva. Although data on clinical efficacy and safety of various ayurvedic treatments in conjunctivitis is published, systematic review is not done. This systematic review and meta-analysis aims to evaluate the efficacy and safety of ayurvedic treatments in conjunctivitis. Methods A literat...
Article
In India, Ayurvedic medicine has its own significance and dominance in the Indian Medicine System. The traditional medicine system of India is not well renowned due to the lack of standardization of herbal drugs. To assess the quality, purity, efficacy, potency, and safety of herbal drugs, standardization is the major aspect. Recently, World Health...
Article
Cancer is one of the most fatal diseases causing deaths of millions of people worldwide. Since actual cancer treatments are rarely efficient and often toxic, there is a demand for innocuous and more effective anticancer drugs. For instance, metal/metal oxide nanoparticles allow controlled drug release and drug delivery to specific targets. In parti...
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Background: Currently, there is no approved treatment for the management of coronavirus disease (COVID-19). Drug repurposing of existing medications could be a possible way to find out a novel therapeutic entity to combat the COVID-19. Aim: To determine the clinical efficacy and safety of an Ayurveda intervention (Guduchighana Vati) in asymptoma...
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Background: Balchaturbharda Churna (BC), is four ingredients (Aconitum heterophyllum Wall. Ex Royle, Pistacia integerrima stew. Ex brandis, Piper Longum Linn. and Cyperus rotundus linn.) Ayurvedic powder dosage form, which is commonly prescribed for treating fever, cough, diarrhea in pediatric setting.Objective: This present study evaluates the pos...
Preprint
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IntroductionOcular allergy is one of the most common prevalent clinical conditions in the world with a rapid increase in the past few years. It has a multifactorial etiology and is a conjunctival inflammatory response due to IgE mediated mast cell activation. The disease is characterized by itching, redness, burning sensation and watering of eyes w...
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Objective To determine the therapeutic efficacy and safety of AYUSH-64 as an add-on to standard care in mild to moderate COVID-19.S Design setting, and interventions This open-label randomized controlled parallel-group trial was conducted at a designated COVID care centre in India in 80 patients diagnosed with mild to moderate COVID-19 and randomi...
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Introduction: Vaccines have emerged as the most effective tool in the fight against COVID-19. Governments all over the world have rolled out the COVID-19 vaccine program for their populations. Oxford-AstraZeneca COVID-19 vaccine (COVISHIELDTM) is widely used in India. A large number of Indian people have been consuming various traditional medicines...
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The current wave of the COVID-19 pandemic is due to the B.1.1.529 variant of the SARS-CoV-2 designated as Omicron. AYUSH-64 a poly herbal drug developed by Central Council for Research in Ayurvedic Sciences (CCRAS) has been recommended by Ministry of AYUSH in asymptomatic, mild to moderate COVID-19 patients. One of the earlier in-silico studies had...
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BACKGROUND: Abutilon indicum (L.) Sweet (family: Malvaceae) is a perennial herb with golden yellow flowers called as Atibala in Ayurveda. The roots of this plant were widely used in traditional system of medicine as aphrodisiac, uterine tonic, and leaves are used in bronchitis, gonorrhea, fever, and urethritis. AIM: In this study, histological, pow...
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AIM: Tripura is a state that covers wide valleys and plains that make up the vivid landscape. More than half of Tripura remains covered by green and moist deciduous forests. Many rural and tribal communities of the Kailashahar, Unakoti district of Tripura depend on traditional systems for the treatment of ailments. The present work has been conduct...
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Corona Virus disease (COVID-19) has become a global pandemic resulting in large scale morbidity and mortality worldwide. The management of COVID-19 has been a big challenge because of multifactorial pathophysiology and no specific treatment. AYUSH-64, a poly-herbal formulation developed by CCRAS, Ministry of AYUSH, Govt. of India through extensive...
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Tinospora cordifolia (TC) has been reported to prevent hepatotoxicity, whereas other species like Tinospora crispa may be associated with hepatotoxicity. Thus, consumers might develop hepatic injury without correctly identifying the plants that they are consuming. Having proper identification of the source plant becomes a mandate before its use. A...
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Laghu Sudarshan Churna, LSC is an Ayurvedic polyherbal formulation employed for different types of jvaras (fevers). The present study was undertaken to prepare its standardised formulation and to standardise the finished product using quality control procedures mentioned in Ayurvedic Pharmacopoeia of India (API). For this, four batches of the finis...
Article
Vishamusthi (Strychnos nux-vomica Linn.), a medicinal plant described as Upavisha (semi-poisonous) group of Ayurvedic Pharmacopoeia of India. Vishamusthi has widely been used and being practiced in several illness namely nervous debility, paralysis, weakness of limbs, sexual weakness, dyspepsia and etc. Ayurveda practices strictly recommend the use...
Article
Ayurveda is an ancient science of India and helps the human body to keep fit while providing cures from indigenous plants, animal and mineral origin products for various ailments. In Ayurveda literature, Berberis aristata has been described as a major plant possess antidiarrheal, antimicrobial, antiprotozoal and antitrachoma activity and used in fo...
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BACKGROUND: The COVID-19 virus is a new contagious pathogen which has made a huge impact on health, economic and societal perspectives of our country. Early detection, rapid isolation, and adoption of effective infection prevention and control (IPC) measures are key to preventing and controlling COVID-19 infection. Patients are now receiving sympto...
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AIM: The present survey work aims to explore and document the traditional healing practices of medicinal plants that have been used by the Rabha tribe of Ri-Bhoi district, Meghalaya, India. MATERIALS AND METHODS: The medico-ethno-botanical survey was carried out in densely populated areas of the Rabha tribe in Ri-Bhoi district of Meghalaya. The doc...
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AIM: The present survey work aims to explore and document the traditional healing practices of medicinal plants that have been used by the Rabha tribe of Ri-Bhoi district, Meghalaya, India. MATERIALS AND METHODS: The medico-ethno-botanical survey was carried out in densely populated areas of the Rabha tribe in Ri-Bhoi district of Meghalaya. The doc...
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Abstract: BACKGROUND: The scheduled caste (SC) population of India, especially women and children, lags behind others in the health scenario and the problem should be addressed with emergency concern. AIM: The aim of this article is to describe the health-related demography of women and children of SC population in selected areas of Thiruvananthap...
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BACKGROUND: Acid peptic disease (APD) has a negative impact on patients' quality of life and general health status of the individuals. There are a number of case studies and clinical trials on efficacy of Ayurvedic interventions in the management of APD. However, a systematic review of these researches is not available which is needed to evaluate t...
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BACKGROUND: Kajjali (black sulfide of mercury) is prepared with mercury and sulfur as per Ayurvedic classics and is an important ingredient in many Rasaushadhis (herbo-mineral/metallic drugs)/ Ayurvedic medicines. Here, an attempt has been made to understand its chemical composition and microstructure characterization of this drug using AAS/ICP-AES...
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BACKGROUND: Diospyros exsculpta Buch.-Ham. (DE) belongs to the genus Diospyros, is an underutilized plant and needs to explore its phytochemical and biological activities. OBJECTIVES: The Present study aimed to compare phytochemical and biological activities such as antioxidant, antimicrobial, and protein-binding assay of twig and stem bark of D...
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INTRODUCTION: Healthcare workers (HCWs) are high-risk individuals in the management of epidemics caused by highly contagious disorders such as coronavirus disease 2019 (COVID-19). Standard of care (SOC) for the prevention of exposure can be greatly supported with SOC measures to improve the immune response. The purpose of this study was to evaluate...
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BACKGROUND: Kajjali (black sulfide of mercury) is prepared with mercury and sulfur as per Ayurvedic classics and is an important ingredient in many Rasaushadhis (herbo-mineral/metallic drugs)/ Ayurvedic medicines. Here, an attempt has been made to understand its chemical composition and microstructure characterization of this drug using AAS/ICP-AES...
Article
Background Vitex negundo plants beautiful gift of Nature to humankind, and we must conserve for the future. This plant has many uses in Ayurveda, Homeopathy, and Allopathy to treat several diseases like venereal diseases, Urinary problems, cough and fever, asthmatic pain, female reproductive problems. Purpose This study aimed to perform the compar...
Article
Background : Aegle marmelos is a traditional plant belonging to India. Very few and sporadic works are there in the literature regarding the physicochemical evaluation of the plant. Method : The major parameters of this study includes the quantification marmelosine, WHO-recommended physicochemical investigation, preliminary phytochemical examinati...
Book
Full-text available
https://ayushportal.nic.in/pdf/Document_Ayurveda.pdf
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Background: The evidence on the efficacy and safety of Ayurveda interventions as an add-on to the standard conventional care for coronavirus disease-2019 (COVID-19) is limited. Aim and objective: This study was planned to explore the potential of AYUSH-64 as an add-on to conventional care in improving the clinical recovery and negative reverse t...
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Background Trigonella foenum-graecum (Methi) is a leguminous plant and botanically known as Trigonella foenum-graecum Linn, belong to the family Fabaceae. Trigonella foenum-graecum is used for a variety of health conditions, including digestive problems, bronchitis, tuberculosis, fevers, sore throats, wounds, arthritis, abscesses, swollen glands, s...
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Objective: To assess the efficacy and safety of Chyawanprash in preventing SARS-CoV-2 infection among health care personnel working at COVID-19 isolation ward. Setting: A hospital designated as COVID-19 care centre in Delhi, India Participants: Apparently healthy health care workers (HCWs) of age 20 to 60 years who were RT PCR negative and asymptom...
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Objectives: To provide a broad evaluation of the efficacy and safety of Ayurveda interventions for the management of sinusitis. Methods: Five electronic databases for published research articles, three databases for the dissertation/doctoral thesis works, clinical trial registries, and hand searches were done till May 2021. All comparative clini...