Nancy Dudek

Nancy Dudek
  • M.S. Zoology
  • Virginia Tech

About

8
Publications
614
Reads
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101
Citations
Introduction
Skills and Expertise
Current institution
Virginia Tech
Additional affiliations
January 2000 - January 2006
Buck Institute for Research on Aging
Position
  • Research Associate

Publications

Publications (8)
Article
Full-text available
Our national data and infrastructure security issues affecting the “bioeconomy” are evolving rapidly. Simultaneously, the conversation about cyber security of the U.S. food and agricultural system (cyber biosecurity) is incomplete and disjointed. The food and agricultural production sectors influence over 20% of the nation's economy ($6.7T) and 15%...
Article
Full-text available
The nematode Caenorhabditis elegans has become one of the most widely used model systems for the study of aging, yet very little is known about how C. elegans age. The development of the worm, from egg to young adult has been completely mapped at the cellular level, but such detailed studies have not been extended throughout the adult lifespan. Num...
Data
DAPI staining of long-lived daf-2(e1368) and wild type N2 nematodes. Young (4-day, top left panel) and middle-aged (24-day, top right panel) daf-2 nematodes were stained with the DNA-reactive dye DAPI. Staining reveals an accumulation of some DAPI-reactive material, similar to that seen in wild-type N2 nematodes but the accumulation of DNA is much...
Data
Nuclear genome copy number quantitation using three different primer sets on three different chromosomes results in highly correlated results. The quantified nuclear genome copy number for each individual nematode used in the study is plotted. (a) Chromosomes II vs. IV, (b) Chromosomes II vs. III, (c) Chromosomes IV vs. III.
Data
Predicted nuclear genome copy number in young adult N2 hermaphrodites.
Data
Two additional quantitative PCR methods reveal the same trends in nuclear genome copy number for N2 and daf-2. Quantitation of nuclear genome copy number via qPCR in individual N2 (a) and daf-2 (b) nematodes. Circles = MJ 96-well plate format (and daf-2(e1368) in b). Triangles = LightCycler (and daf-2(e1370) in b). The mean copy number of genomes p...
Data
The germline deficient mutant glp-4 does not have a wild-type nuclear genome content, even at the permissive temperature. The number of copies of the nuclear genome, as assayed by qPCR, for individual N2 or glp-4 nematodes at either 25 °C or 17 °C are shown. Each dot represents a single worm, and 15 individuals were assayed per condition.

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