Nailoke Pauline Kadhila

Nailoke Pauline Kadhila
University of Namibia | UNAM · Multidisciprinary Research

PhD

About

20
Publications
128,883
Reads
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99
Citations
Introduction
Mycology (Basidiomycetes) Medicinal plants Drug discovery
Skills and Expertise
Education
February 2014 - February 2019
University of Namibia
Field of study
  • Applied Biology
February 2008 - February 2010
University of Namibia
Field of study
  • Applied Biology
August 1995 - August 1998
Zhejiang University
Field of study
  • Agriculture

Publications

Publications (20)
Article
Full-text available
Mushroom substrates are organic materials which mushroom mycelia can digest and which support growth, development and fruiting of mushrooms. Without good substrates, satisfactory yields of mushrooms will not be obtained. Consequently, finding good substrates on which to grow Ganoderma lucidum is of great importance to the medicinal world, and for m...
Article
Full-text available
Pechuel-loeschea leubnitziae is an aromatic and unpalatable shrub traditionally used to treat malaria and related symptoms in some regions of Namibia. Despite the importance of P. leubnitziae in the management of malaria, no studies have evaluated the antiplasmodial activities of this putative antimalarial plant. In this study, antiplasmodial activ...
Article
Full-text available
Medicinal mushrooms have provided a natural source of bioactive compounds since ancient times. Ganoderma is such a mushroom, which has worldwide recognition as a medicinally important mushroom. In this review, the authors provide a detailed summary of indigenous Ganoderma research in Namibia, looking at the ethnomycology, biological activity, physi...
Article
Full-text available
Ganoderma is a genus of mushrooms that is prized in developed nations, especially those in Asia, due to its health-promoting properties, which are attributed to bioactive compounds such as phenolics. However, in developing countries, particularly in Africa, Ganoderma mushrooms are untapped and are barely identified. In this study, we identified Gan...
Article
Full-text available
Ganoderma is a genus of mushrooms that is prized in developed nations, especially those in Asia, due to its health-promoting properties, which are attributed to bioactive compounds such as phenolics. However, in developing countries, particularly in Africa, Ganoderma mushrooms are untapped and are barely identified. In this study, we identified Gan...
Chapter
Mushrooms are a vital component of biologically diverse and healthy ecosystems that contains vitamins, minerals, and protein. With increasing evidence that mushrooms have medicinal effects, such as anticancer and antiviral activities, they offer great hope for various interventions in functional foods and drug development. In some cultures, mushroo...
Article
Full-text available
In this study, face-to-face interviews were conducted to collect data on the indigenous uses and traditional knowledge of Termitomyces mushrooms in Judea-Lyabboroma and Katima rural, Zambezi Region, Namibia. The results showed that Termitomyces were used in the form of powder or paste to heal diseases such as cancer and kidney problems, sexually tr...
Chapter
Traditional medicines are an important commodity in the lives of the Namibian communities, especially those in resource-poor settings or those that do not accept allopathic medicines. However, the knowledge and practice of traditional medicines (TM) is decreasing in these communities in Namibia, due to cultural and lifestyle influences from western...
Article
Background: Kalahari truffle (Kalaharituber pfeilii) is found in the Kalahari desert and nearby regions (Africa). This study assessed the microbiological quality and safety, mycotoxins, and heavy metals contents of raw Kalahari truffle sold in Namibia. Methods: Batches of Kalahari truffles were purchased from informal markets and different vendors...
Article
Full-text available
The application of green chemistry for the synthesis of nanoparticles is said to be environmentally friendly and cost efficient. The paper reports on the cell anti-proliferative activity of Pechuel-loeschea leubnitziae, synthesis of silver nanoparticles using P. leubnitziae and characterization. The UV-vis spectroscopy confirmed presence of a peak...
Article
Trametes Fr. is widely characterized as a polyporoid cosmopolitan genus which is presented in almost any type of forest environments. It is characterized by a combination of pileate basidiocarp, porous hymenophore, trimitic hyphal system and thin-walled basidiospores which do not react in Melzer's reagent. Dry polypores were collected from Northern...
Article
Full-text available
This paper looked at basidiomycetes and their antiplasmodial activities from different studies. The purpose of this short review is to encourage more research on fungi in order to address major and complicated infectious diseases like malaria, especially in Africa. Mushrooms represent a major and largely untapped source of potent pharmaceutical pro...
Article
Full-text available
Ganoderma lucidum is a mushroom which shows antitumor, anti-inflammatory and cy-toxic activity and grows prolifically in warm climates on decaying hardwood logs and stumps. An experiment was done at the University of Namibia to cultivate the indigenous G. lucidum; however, compared to results from other countries the mushroom took much longer to gr...
Article
Full-text available
Malaria remains one of the most prevalent infections in the tropical regions of the world. The increased resistance of the parasite to many available antimalarial backs the need to develop novel antimalarial drugs with effective mode of action. Several fungi with antiplasmodial properties have been proved as sources for novel antiplasmodial compoun...
Article
Full-text available
In this article Mushrooms grown on substrates treated with different concentrations of manganese , copper, lead and zinc were studied. Mushrooms grown on substrates treated with different concentrations of manganese, copper and zinc fruited at about the same time (4 weeks after spawning). The mushrooms treated with lead took about 2 more weeks to f...

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