Nagihan Inan

Group Florence Nightingale Hastaneleri · Radiology

Background Whole-body positron emission tomography/magnetic resonance imaging (WB-PET/MRI) is increasingly used in the initial evaluation of oncology patients. The purpose of this study was to compare the diagnostic performance of WB MRI sequences, attenuation-corrected raw data positron-emission tomography (AC PET), and PET/MRI fused images to det...

Purpose: The aim of our study was to determine which imaging method was superior in detecting brain metastases by comparing contrast-enhanced MRI and 18F FDG PET / MRI which were obtained simultaneously. Methods: From August 2015 to December 2018, 480 consecutive patients with histopathologic proven primary malignancy (188 men and 292 women; mean a...

Introduction To evaluate diagnostic performance of apparent diffusion coefficient (ADC) heterogeneity index to differentiate brain metastasis (BM) from normal appearing brain parenchyma (NABP) and to find out the correlation between 2-[¹⁸F]-fluoro-2-deoxy-D-glucose (¹⁸F-FDG) standardized uptake value (SUV) and ADC heterogeneity index derived from h...

Background PET/MRI is a hybrid imaging modality and uses for evaluating oncology patients with its benefits of combination of soft tissue contrast and glucose metabolism. Aims To evaluate the role of simultaneous derived apparent diffusion coefficient (ADC) heterogeneity index and 2-[¹⁸F]-fluoro-2-deoxy-D-glucose (¹⁸F-FDG) standardized uptake value...

The aim of this study was to investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and pancreatic steatosis (PS) in patients with biopsy-proven NAFLD. 228 patients with biopsy-proven NAFLD patients who admitted to the Faculty of Medicine of Demiroglu Bilim University between 2004 and 2019 were included in the study. Demograp...

Background/Aim: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has deeply affected life all over the World. The World Health Organization named this disease as COVID-19. The most important factor in the transmission of the disease is asymptomatic carriers. We’ve tested all oncology patients, that receive anti-cancer therapy, for COVİD...

Purpose: To evaluate the Intravoxel Incoherent Motion (IVIM) parameter alterations of liver metastases of colorectal carcinoma (CRC) during antiangiogenic bevacizumab combination therapy. Methods: Twenty-five CRC liver metastases who were all treated with bevacizumab in combination with FOLFOX-or-FOLFIRI protocols were enrolled in the study. MRI...

Objective: To evaluate the diagnostic accuracy of Intravoxel Incoherent Motion (IVIM) parameters for assessment of tumor response after locoregional treatment (LRT) of hepatocellular carcinoma (HCC). Methods: Fifteen patients with HCC who had undergone LRTs (11 transarterial radioembolization, 4 transarterial chemoembolization) were included. In...

Background: The purpose of this study was to determine the utility of some imaging findings in predicting microvascular invasion (MVI) and hepatocellular carcinoma (HCC) recurrence risk after liver transplantation. Method: This retrospective study included 123 patients with histopathologically proven HCC at explant. All HCCs were classified as M...

Objectives: Although endoscopic management is considered as the first-line treatment for biliary strictures, it may be challenging in living donor liver transplant recipients due to the complex nature of duct-to-duct reconstruction. In this study we present the use of a pigtail drainage catheter as a biliary stent to treat biliary strictures after...

Background: Venous outflow reconstruction of modified right-lobe liver grafts has been shown to prevent the occurrence of graft congestion and subsequent complications, including graft loss. In the present study, we aimed to investigate the safety and efficacy of Dacron grafts for venous reconstruction in living donor liver transplantation (LDLT)....

Purpose: Estimation of graft volume is critical in living donor liver transplantation (LDLT). In this study, we aimed to evaluate the accuracy of software-aided automated computer tomography (CT) volumetry in the preoperative assessment of graft size for LDLT and to compare this method with manual volumetry. Materials and methods: Forty-one dono...

Background: To evaluate the diagnostic accuracy of intravoxel incoherent motion (IVIM) parameters in estimation of hepatocellular carcinoma (HCC) grading. Materials and methods: Twenty-nine patients with histopathologically diagnosed as 42 HCC at explant were included in this retrospective study. All patients were examined by 1.5T magnetic reson...

Purpose: To evaluate the diagnostic accuracy of intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI) parameters in the differential diagnosis of portal vein thrombus (PVT). Methodology: Thirty-five patients with PVT were enrolled in this retrospective study. Precontrast axial in-phase and out-of-phase T1-weighted (W) turbo fi...

Background The conventional radiologic features that differentiate benign from malignant bone lesions were originally described using radiography (X-ray [XR]). When evaluating sectional imaging studies such as magnetic resonance imaging (MRI) and computed tomography (CT), one may apply these principles to identify malignant bone lesions. The aim of...

Background: Diffusion-weighted imaging (DWI) has become an established diagnostic modality for the evaluation of liver parenchymal changes in diseases such as diffuse liver fibrosis. Aims: To evaluate the parenchymal apparent diffusion coefficient value (ADC) changes using diffusion-weighted imaging (DWI) during telaprevir-based triple therapy....

Background: Imaging plays a critical role not only in the detection, but also in the characterization of lung masses as benign or malignant. Objectives: To determine the diagnostic accuracy of dynamic magnetic resonance imaging (MRI) in the differential diagnosis of benign and malignant lung masses. Patients and methods: Ninety-four masses wer...

Purpose: Imaging plays a critical role not only in detection but also in characterization of pleural thickening as benign or malignant. The aim of the study was to investigate the value of diffusion-weighted (DW) imaging in the differential diagnosis of benign and metastatic malignant pleural thickening. Materials and methods: Thirty-four patien...

Objective: Depression frequently occurs in patients with heart failure as similar pathophysiological mechanisms present in both these diseases. Patients with dilated cardiomyopathy (DCM) have a high incidence of clinically asymptomatic silent cerebral infarction (SCI). This study aimed to evaluate the relation between SCI and major depressive diso...

Gunshot wound injury to the external genitalia is relatively uncommon. However, if a testis is affected in such a case, early surgical exploration should be carried out. A 16-year-old boy presented with right testicular rupture. Tunica albugineal defect could not be closed primarily. We used a Tutoplast® processed bovine pericardium to repair the d...

To detect the abnormalities of the anterior visual pathways in children with amblyopia with diffusion tensor imaging. Ten children with unilateral amblyopia, 5 children with bilateral amblyopia, and 10 control children were treated using diffusion tensor imaging scanning in this institutional practice. Fractional anisotropy and mean diffusivity val...

To evaluate the diagnostic efficiency of the diffusion parameters measured by conventional diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) for discrimination of malignant breast lesions from benign lesions and the normal breast. The study included 52 women with 55 breast lesions (30 malignant, 25 benign). DTI and DWI were perfor...

To determine the performance of diffusion-weighted magnetic resonance imaging in differentiating lymphoma from sarcoidosis in mediastinal-hilar lymphadenopathy. Forty-four mediastinal-hilar lymphadenopathy were examined in 27 patients with T1- and T2-weighted conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000...

We report an unusual case of an invasive thymoma with a thrombus in the right atrium and describe the radiological findings consistent with the malignant nature of the thrombus. The thrombus showed significant enhancement on computerized tomography images similar to the tumoral mass. On magnetic resonance imaging, both the tumor and the thrombus ha...

Objective: To evaluate the diagnostic accuracy of liver apparent diffusion coefficient (ADC) measured with conventional diffusion-weighted imaging (CDI) and diffusion tensor imaging (DTI) for the diagnosis of liver fibrosis and inflammation. Materials and methods: Thirty-seven patients with histologic diagnosis of chronic viral hepatitis and 34...

Purpose: To evaluate the diagnostic accuracy of 3T MRI in preoperative staging of myometrial invasion. Methods: Twenty-eight women with histological diagnosis of endometrial carcinoma were included in this prospective study. After T2-W SS-TSE and DWI, dynamic series of T1-W THRIVE images were obtained (0-180 s) followed by a T1-W THRIVE sequence...

The aim of the study was to evaluate the role of diffusion-weighted magnetic resonance imaging in the differential diagnosis of lung lesions. PATIENTS AND METHODS.: Sixty-seven patients with lung lesions (48 malignant, 19 benign) were included in this prospective study. Signal intensities (SIs) were measured in diffusion-weighted MR images that wer...

Background: In this trial, we aimed to investigate the clinical features and treatment methods of popliteal artery diseases using digital subtraction angiographic findings. Methods: A total of 1263 popliteal arteries of 690 patients (566 males, 124 females; mean age 64 years; range 8 to 85 years) for whom all clinical data were available and who un...

We aimed to evaluate the performance of diffusion-weighted magnetic resonance imaging in differentiating malignant from benign mediastinal lesions. Fifty-three mediastinal lesions were examined with T1- and T2-weighted (W) conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000 s/mm² values and apparent diffusion...

Gorham-Stout syndrome, also called "disappearing bone disease, diffuse cystic angiomatosis of bone, disseminated lymphangiomatosis, Gorham's vanishing bone disease, phantom bone disease or idiopathic massive osteolysis, is a rare disease of unknown etiology and pathogenesis. It is characterized by rapidly progressive localized massive osteolysis as...

Background The purpose of the study was to evaluate the value of diffusion-weighted imaging in the differential diagnosis of haemangiomas from metastases of the liver. Patients and methods. We analyzed 69 lesions in 38 patients (33 haemangiomas; 36 metastases) in the retrospective study. Diffusion-weighted imaging was performed using a breath-hold...

Patients who undergo a Fontan procedure experience some degree of liver disease. Hemodynamic changes such as central venous hypertension, depressed dynamic cardiac output, and late ventricular dysfunction combined with long-standing hypoxia preceding the Fontan procedure all are recognized risk factors for hepatic injury. The histopathologic change...

To evaluate the value of conventional and diffusion-weighted (DW) magnetic resonance imaging (MRI) in the diagnosis of extrahepatic hydatid cysts. Forty-one extrahepatic hydatid cysts (12 renal, 6 pulmonary, 5 peritoneal, 4 bone, 3 soft tissue, 3 pancreatic, 2 splenic, 2 retroperitoneal, 1 adrenal, 1 scrotal, 1 diaphragmatic, and 1 cardiac) were in...

Leiomyoma of the seminal vesicle is an extremely rare tumour. The diagnosis of this entity is important when it co-exists with prostatic carcinoma, since it can simulate tumour extension from prostate or bladder cancer on MR imaging and lead to overstaging. In this report, we describe a 74-year-old man with a leiomyoma of the seminal vesicle that m...

Jarcho-Levin syndrome (JLS) is a congenital disorder characterized by a variety of vertebral and costal anomalies that result in thoracic deformity. Hitherto, a plethora of associated anomalies have been described in several reports. In this report, the authors describe a case of JLS who has Wilms tumor and bilateral cystic renal disease. To the au...

Opsoclonus-myoclonus-ataxia (OMA) syndrome is a rare neurobehavioral paraneoplastic disorder in children with neuroblastic tumors. The neurologic symptoms are generally treated with a number of immunosupressive and immunomodulating agents. A 4-year-old previously healthy male patient was admitted to the authors' center with progressive ataxia, gait...

Epithelioid cell granulomas may be associated with several neoplasms. Lymphomas may mimic or are associated with epithelioid granulomas. In this article the authors report a child with granulomatous reaction in B cell non-Hodgkin lymphoma and intracardiac thrombosis. Although cancer alone is a risk factor for thromboembolism, thrombosis is a multif...

To evaluate the value of diffusion-weighted imaging (DWI) in the differential diagnosis of pleural effusions. 58 pleural effusions (21 transudative, 37 exudative) were included in this prospective study. Single-shot echo-planar spin echo DWI was performed with two b factors (500 and 1000 s/mm (2)), and apparent diffusion coefficients (ADCs) were ca...

Congenital tracheobiliary and bronchobiliary fistulae are rare malformations in which patent communications exist between the respiratory system and biliary tract, respectively. We present a newborn who was admitted with respiratory distress and bilious tracheal discharge. Investigation revealed a bronchobiliary fistula originating from the left ma...

Pleuropulmonary blastoma (PPB) is a very rare intrathoracic malignancy in childhood. It is an aggressive embryonal or blastemic neoplasm usually occurring in children younger than five years of age. PPB is treated with aggressive multimodal therapies consisting of surgery and chemotherapy. We present a case with PPB type II successfully treated wit...

The purpose of our study was to evaluate the value of diffusion-weighted imaging (DWI) in the differential diagnosis of pancreatic cysts. Forty-two cysts (16 simple cysts, seven pseudocysts, five abscesses, three hydatid cysts, two serous cystadenomas, three mucinous cystadenomas, two mucinous cystadenocarcinomas, four cystic degenerated adenocarci...

Epidermal nevus syndrome is a neurocutaneous disorder characterized by the association of epidermal nevi with central nervous system or skeletal abnormalities. Central nervous system abnormalities include hemimegalencephaly, hydrocephalus, various migration disorders, intraspinal lipomas, and enlarged spinal roots. Rarely, vascular anomalies cause...

The purpose of the study was to determine if color Doppler ultrasonographic (US) quantitative flow parameters are valuable to differentiate malignant peritoneal or omental involvement from benign causes. Twenty-six consecutive patients with peritoneal or omental thickening detected by gray scale US, computed tomography, and magnetic resonance under...

Cadaveric studies yielded promising results in sexing the temporal bones by measuring the lateral angle of the internal acoustic canal meatus. In this study, we evaluated the capability of computerized tomography of the temporal bone to reproduce these results. Lateral angle of the internal acoustic canal meatus was measured in 92 patients (47 fema...

Distal vaginal agenesis is one of the rarest congenital malformations of female genital tract. We describe successfully operated teenaged monozygotic twins by combined abdominal and perineal approach. The imaging studies and surgical experience were presented.

Unlike other islet-cell tumors, insulinomas are usually benign. Most insulinomas have a high signal intensity on T2-weighted images and a low signal intensity on T1-weighted images, and are hyperintense on immediate post-gadolinium images. However, in rare cases, insulinomas may be hypointense on T2-weighted images and on immediate post-gadolinium...

To evaluate the value of dynamic MR imaging in the differential diagnosis of adrenal adenomas and malignant tumors, especially in cases with atypical adenomas. Sixty-four masses (48 adenomas, 16 malignant tumors) were included in this prospective study. Signal loss of masses was evaluated using chemical shift MR imaging. Five dynamic series of T1-w...

The purpose of our study was to evaluate the value of diffusion-weighted imaging (DWI) in the differential diagnosis of simple and hydatid cysts of the liver, particularly in the completely liquid type of hydatid cyst. Eighty-two cysts (43 simple cysts, 39 hydatid cysts) were included in this prospective study. DWI was performed using a breath-hold...

Introduction: Proteus syndrome (PS) is a rarely seen, sporadic disorder with a wide range of abnormalities including asymmetrical overgrowth, skin lesions, dysregulated adipose tissue, and vascular malformations. Brain and spinal malformations are extremely rare; syringohydromyelia and arachnoid cyst have not been reported previously. Materials a...

Lhermitte-Duclos disease (LDD) is a rare hamartomatous focal or diffuse enlargement of the cerebellum with unclear etiology. The characteristic magnetic resonance imaging (MRI) appearance consists of a non-enhancing mass in the cerebellar hemisphere with a striated pattern. The slow growing behavior of this benign lesion is characteristic. In a few...

Colitis cystica profunda (CCP) is an uncommon benign condition characterized by mucin-filled cysts located in the submucosa, frequently associated with the solitary ulcer and rectal prolapse syndromes. The diagnosis of this entity is important as it can mimic rectal cancer and therefore may result in unnecessary surgical resection. Endoscopic exami...

Although primary breast carcinoma is one of the most common malignancies worldwide, metastases to the breast are relatively uncommon. The incidence of metastasis to the breast from malignant neoplasms other than primary breast carcinoma varies from %1-5. Both the clinicians and pathologists must be very careful in distinguishing metastasis from pri...

The aim of this study is to determine the role of magnetization transfer ratio (MTR) in the early period of Parkinson disease (PD). Clinically diagnosed 33 patients with PD in the first year of diagnosis, and 30 healthy volunteers were assessed. Magnetic resonance imaging (MRI) was performed without and with magnetization transfer (MT) imaging. Sig...

Objectives: To evaluate patient characteristics and treatment results of pediatric patients with Hodgkin lymphoma. Methods: Hodgkin lymphoma patients (9 males, 4 females; mean age 9.2±3.5; range 4 to 15 years) at pediatric age group (<18 years) treated in our oncology center between 2003 and 2006 were retrospectively analyzed. Results: The most com...

Purpose: To evaluate the efficacy of thin slice and small FOV MRI technique using body coil, performed after distending the rectum with saline solution in the preoperative staging of rectum cancer. Materials and Methods: MR imaging of 36 patients with rectum cancer was done by distending the rectum with saline solution, using body coil, with thin s...

OBJECTIVES: To evaluate patient characteristics and treatment results of pediatric patients with Hodgkin lymphoma. METHODS: Hodgkin lymphoma patients (9 males, 4 females; mean age 9.2±3.5; range 4 to 15 years) at pediatric age group (<18 years) treated in our oncology center between 2003 and 2006 were retrospectively analyzed. RESULTS: The most com...

Popliteus muscle sesamoid bone, also known as cyamella, is an accessory ossicle that is located in the vicinity of the proximal musculo tendinous junction. While commonly seen in small mammals such as cats and dogs, its presence in humans is very rare. In this report, we present the radiological findings of the popliteus muscle sesamoid bone, incid...

The purpose of our study was to compare gadopentate dimeglumine (Gd-DTPA) and gadobenate dimeglumine (Gd-BOPTA) for the evaluation of myocardial infarction (MI) and in the grading transmural extent on late-contrast enhanced cardiac magnetic resonance imaging. Twenty-three patients with clinically proven MI were examined with the use of 0.2 mmol/kg...

PURPOSE Gadobenate dimeglumine (Gd-BOPTA) has a two-fold higher T1 relaxivity compared with gadopentetate dimeglumine (Gd-DTPA). The purpose of this study is to compare 0.2 mmol/kg gadopentate dimeglumin (Gd-DTPA) with the 0.1 mmol/kg gadobenate dimeglumine (Gd-BOPTA) for the detection and the transmural extent of myocardial infarction on late enha...

We retrospectively reviewed MR studies on 10 patients with renal-related perinephric fluid collections who underwent MRI in three institutions between January 2001 and August 2004. All patients underwent MRI of the abdomen and T1-weighted, T2-weighted and serial contrast-enhanced images, including delayed-phase contrast-enhanced images 10-12 min af...

Laparoscopic surgery is a good alternative to the open technique for treating hernias in female paediatric patients. The laparoscopically inverted and sutured hernia sac forms a nodule, the long-term fate of which has not been previously studied radiologically. To describe the early and delayed US changes after laparoscopic inversion and suturing o...

In this study, the occurrence of Sirelina orduensis Meric and Inan (1996) in Upper Maastrichtian levels in the different outcrops of Ilgaz (Cankiri) region was discovered. Sirelina orduensis was described first time by Meric and Inan(1996) in Golkoy formation (Ordu).Sirelina orduensis Meric and Inan different from other formanifera by their microgr...