Nagib Ali Elmarzugi

University of Tripoli | UOT · Department of Industrial Pharmacy

A case study of patient presented with developed wound infection with Pseudomonas aeruginosa (leukocytosis). The strains of P. aeruginosa isolated from Sheffield General Northern Hospital (UK) and studied for phenotypic and genotypic identifications. This present study were conducted in Sheffield Hallam University (UK) and was aimed to evaluate the...

Background and objectives. This study was cross sectional study conducted in maternity ward of Benghazi Medical Center (BMC) with the aim of investigating the cause of infection after cesarean section. Methods. Data was collected by using open-closed questionnaires. About 50 swabs were collected from wound patient and operation therapy environment....

Results: The virgin coconut oil nanoparticles are solid lipid nanoparticles form and were stable for a reasonable length of time at room temperature, using probe sonicator and lab homogenizer to form two-phase emulsion. The average particle size inside the emulsion was obtained at a fixed period of time repeatedly. Overall, average particle sizes...

The AB3 molecule recorded Log P using HyperChem software at 4.18, EHOMO/LUMO gap at 8.195 eV, total energy at -76645.750 Kcal/mol, binding energy at -3979.363 Kcal/mol and dipole moment at 4.87 D. The AI3 recorded Log P at 4.60, EHOMO/LUMO gap at 7.512 eV total energy at -72557.745 Kcal/mol binding energy at -3827.571 Kcal/mol and dipole moment at...

From the successful completion of the series of Libyan conference on medical and pharmaceutical sciences, we are delighted to welcome you to the fourth Libyan Conference of Medical and pharmaceutical sciences (4th LCMPS 2020). The congress is scheduled to take place in the city of Janzur, Libya, on November 14, 2020. This conference will deliver yo...

Background and objectives: Even with the widespread repetition of organizing events and conferences by hosting organizations, little is known about the influence of such meeting on attendee’s satisfaction. However, up to our knowledge, there is no exploratory survey measured the satisfaction of conference attendees in Libya. Hence, this study sough...

Background and objectives: Even with the widespread repetition of organizing events and conferences by hosting organizations, little is known about the influence of such meeting on attendee’s satisfaction. However, up to our knowledge, there is no exploratory survey measured the satisfaction of conference attendees in Libya. Hence, this study sough...

We are pleased to announce the reappearance of the AlQalam journal of medical and applied sciences (AJMAS) having been interrupted for one year and half, except for conference proceeding. The current issue will be the first online issue under the sponsorship of the University of Tripoli Alahlia (UTA), Janzur, Libya. Despite the uprising difficultie...

Massive limestones were used in construction of ancient Egyptian tombs, temples, obelisks and other sculptures. These stones are always exposed to physico-mechanical deterioration and destructive forces, leading to partial or total collapse. The task of reassembling this type of artifacts represents a big challenge for the conservators. Recently, t...

Editorial Contribution

In order to develop a self-nanoemulsifying system, three components, olive oil, Tween 80, and Capmul, were used to construct a ternary phase diagram that helped to find the optimum formulation, which was loaded with nifedipine. The effect of sonication on drug loading was also evaluated. After that, measurement of the droplet size, size distributio...

The conservation of ancient Egyptian outdoor carved limestone sculpture is an important issue. This type of artifact is generally exposed to complex weathering processes, and the resulting physico-chemical decay causes unwanted changes in the stone structure and surface. The conservation of carved limestone is a difficult task, requiring the use of...

The marble columns at many historic sites represent one of the most important and fundamental architectural elements in a building. They are almost always subject to serious damage, whether in the base, middle, or crowns of columns by fungal infection. In most cases, the microbial deterioration affects the physical and mechanical properties of hist...

Nowadays, nanotechnology is widely applied for the development of highly efficient products in the pharmaceutical and cosmetic industries. Converting bioactive materials to nanoscale not only increases their biocompatibility but also increases their effectiveness, even when lower doses are used. Metal nanoparticles can be synthesized by fungal cell...

Abstract: Background: Nigella sativa L. (N. Sativa) has been reported to have biological activities such as anti-bacterial, anti-inflammatory, anti-oxidant and anti-fungal activities. Objective: This study aims to develop N. Sativa colloidal-emulgel with the evaluation of its antibacterial, anti-oxidant and in-vivo irritation and sensation testing....

Environmental deterioration factors are constantly increasing, causing unwanted aesthetic changes to stone artworks due to exposure to various physical and chemical deterioration factors. Inorganic nanoparticle-filled polymer composites have extended their multiple functionalities to various applications, including cultural heritage conservation. T...

Cordyceps is one of the most well-known mushroom with numerous bioactive compounds possess wide range of biotherapeutic activities. This mushroom has been used for many years as medicinal food particularly in China and in different regions of south East Asia. Cordycepin is a nucleoside compound extracted from different species of Cordyceps and cons...

It is estimated by the World Health Organization (WHO) that most of the world’s population depends on herbal medicine for their health care. Nigella sativa (N. sativa), also known as black-caraway and as “Kalonji,” is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical cons...

Stone surfaces and façades of historic buildings, due to their predominately outdoor location, suffer from many deterioration factors, including air pollution, soluble salts, relative humidity (RH)/temperature, and biodeterioration, which are the main causes of decay. In particular, the façades of the buildings deteriorate with direct exposure to t...

The unwanted changes in valuable historic calcareous stone monuments due to exposure to many physical and chemical effects may lead to its deterioration. The growing interest in the field of conservation of stone monuments encourages the development of consolidation and water-repellent materials. The aim of this study is to evaluate the effectivene...

Transboundary Animal Diseases (TADs) pose serious worldwide risks to livestock and food security, as well as to humans. The world has been facing severe economic losses from epidemics of, for example, foot and mouth disease (FMD) and blue tongue disease(BT). After the turmoil of the Arab Spring in 2011, the patterns of livestock movement between No...

Innovative Minds: Holistic Healthcare Through Pharmaceutical Sciences

Innovative Minds: Holistic Healthcare Through Pharmaceutical Sciences

‘Innovative Minds: Holistic Healthcare Through Pharmaceutical Sciences’

Innovative Minds: Holistic Healthcare Through Pharmaceutical Sciences

The deterioration of calcareous stones materials used in artistic/architectural field is one of the most serious problems facing conservation today. The aim of this study was to evaluate the effectiveness of nanosized particles of calcium hydroxide (slaked lime) as a consolidation and protection material dispersed in acrylic copolymer, poly ethylme...

Ancient Egypt stone monuments represent an important part of worldwide cultural heritage, but due to their prevalently outdoor location, they are generally subject to a complex series of weathering and decay processes. In addition to physical and chemical factors, biological agents play an important role in the deterioration of cultural heritage ca...

M HCl (shown at right) 2 in 2 M FeCl 2-A M HCl (shown at left) 2 in 3 M FeCl 1-B 1.0 M NH3 in water. (B) (A) Aim The purpose of this project was to show a method of preparation of magnetite nanoparticles. The most recent surface-modifications related to the use of iron oxide nanoparticles for magnetically controlled drug delivery. After repeating t...

Solid Lipid Nanoparticles in Cosmetics Nesrein M. Bendala1, Nagib A. Elmarzugi1, 2, Halla H. Shwekh1, , Ashraf A. Alnaas1 1National Nanotechnology Project (NNP), Biotechnology Center (BTC), Libyan Authority for Research, Science and Technology (LARST), Tripoli – Libya. 2Dept. of Industrial Pharmacy, Faculty of Pharmacy, Tripoli University, Tripoli...

Hylocereusundatus is typically the most cultivated vine cactus belonging to the family of Cactaceae, originating natively from Mexico and America. Commonly, it is well known under the name of " dragon fruit " or " pitaya ". In Malaysia, it is also called 'buahnaga' which gives the meaning of dragon fruit. Besides its attractive coloration, the frui...

Conference Poster

The application of Nanoemulsion is one of the growing technologies used in food, cosmetic and pharmaceutical industries as a novel delivery system for drugs and lipophilic materials such as essential oils, flavours, colours and fatty acids. These technological application of nanoemulsions have increasing used in the cosmetic applications due to the...

In this century, the development of nanotechnology is projected to be the establishment of a technological evolutionary of this modern era. Recently, nanotechnology is one of the most active subjects of substantial research in modern material sciences and hence metal nanoparticles have a great scientific interest because of their unique optoelectro...

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VCO Emulsions were prepared using high-speed stirrer with various surfactant concentrations and mixing ratio. The resultant mixture was added with distilled water. Among the formulation, best optimum formulation was selected for secondary homogenization using High Pressure Homogenizer (HPH) to produce of VCO Nanoemulsion in the range 20-200nm. The...

Conference Poster: 11th Nanoscience and Nanotechnology conference Middle East Technical University, Ankara - Turkey; June 2015

Objectives: Due to the high dynamics of pharmaceutical products markets, developments of new products using latest innovative technology are becoming a norm of many pharmaceutical companies. Nanoscale materials such as nanoemulsion (NE) offer advantages such as the controllable droplet size, long-term stability, and power solubilization ability. It...

Saccharomyces boulardii is non-pathogenic probiotic yeast with many health benefits. In the present work, studies were carried out to improve cell growth kinetics to produce cell mass of this biotherapeutic yeast in semi-industrial scale. At first, five different media were screened to select the most appropriate formula for biomass production. The...

Bacillus thuringiensis subsp. Israelensis (Bti), has proven to be a safe and effective larvicide for controlling mosquito and black fly larvae. The effect of cultivation and bioprocess development on Bti growth and sporulation was investigated in shake flask level and batch cultivation in the semi-industrial scale 16-L stirred tank bioreactor. For...

Cordyceps militaris is one of the well described mushrooms and has been extensively used in Traditional Chinese Complementary Medicine (TCCM) since many centuries. It has been cultivated naturally or in submerged culture using different types of media. Fungal mycelia contain adenosine, cordycepin, and polysaccharides, which are responsible for its...

The objective of the current paper was to prepare and evaluate various polymeric films for fungal infection treatment and its impact on volunteer patients. Different Eudragit polymeric films containing Ketoconazole as antifungal drug were prepared by solvent casting technique. The prepared films were tested for their physico-mechanical properties a...

This study presents the effects of two techniques in preparing solid lipid nanoparticles (SLN) incorporated with virgin coconut oil (VCO). VCO-SLNs were prepared using two different techniques which were high pressure homogenizer (HPH) and probe sonicator. HPH was done at 400 bars for six cycle and for probe sonicator, three different amplitudes we...

There is an increasing trend among pharmaceutical industries to use natural bioactive materials as medicinal agents and to use new technologies such as self-nanoemulsifying systems. The solubility and bioavailability of poorly soluble drugs can be enhanced by self-nanoemulsifying systems. Swietenia oil is frequently used because of its antimicrobia...

Understanding the mode involved in the binding of certain molecules to DNA is of prime importance, and PEG offers wide-ranging applications in biological, medical and pharmaceutical contexts. FTIR spectroscopy has been used to characterize how the formed biocomplexes bind or dissociate to/from each other between PEG400-ctDNA under different conditi...

The advances in knowledge about production and stability of dispersed systems enable the development of differentiated vehicles such as nanoemulsions and nanoemulgels, which have been effectively used to increase the bioavailability and improve the stability of the active ingredients. Nowadays there is an intensely usage of natural bioactive materi...

The aim of this study was to characterize nanoemulgel prepared using olive oil and sucrose ester as surfactant. Nanoemulsion is submicron sized emulsion typically in the range of 20-200 nm. Nanoemulgel has emerged as a promising drug delivery of hydrophobic drugs. When hydrogels and emulsions are used in a combination, thus the dosages will be refe...