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Naga Prashant Koppuravuri

Naga Prashant Koppuravuri
Adichunchanagiri University · Pharmaceutical Chemistry

Doctor of Philosophy

About

34
Publications
19,413
Reads
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94
Citations
Additional affiliations
September 2020 - present
Adichunchanagiri Institute of Medical Sciences
Position
  • Professor (Assistant)
July 2019 - August 2020
Teerthanker Mahaveer University
Position
  • Professor (Assistant)
November 2012 - May 2019
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, A.P, India
Position
  • Professor (Assistant)
Education
October 2009 - July 2011
Jawaharlal Nehru Technological University Anantapur
Field of study
  • Pharmaceutical Chemistry
October 2004 - October 2008
Arulmigu Kalasalingam College of Pharmacy
Field of study
  • Pharmaceutical Sciences

Publications

Publications (34)
Article
Full-text available
Green chemistry is the new and rapidly emerging field of chemistry. It involvesnthe utilization of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. In recent decades, a large number of reports related to synthesis of Nitrogen, Oxygen and Sul...
Article
Full-text available
Objective: The main objective of the present study is to synthesize some derivatives of Benzoin that shows promising antimicrobial and anthelmintic activity. Methods: In the current research work, some derivatives of benzoin were synthesized by targeting its ketone group by reacting with various hydrazines, semi carboxamide, and hydroxylamine. The...
Conference Paper
Full-text available
Coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus is a global pandemic that has resulted in over 18.3 million confirmed cases and close to 7,00,000 deaths. In the majority of symptomatic cases COVID-19 results in a mild disease predominantly characterised by upper respiratory tract symptoms. Reverse transcript...
Article
Full-text available
Background: Tragacanth, a natural gum, is frequently used as stabilizerfor colloidal systems and as a binder in tablets. Materials from naturalsources are in increasing demand to solve the current global environmentalproblems arising from synthesis involving petroleum‑based substances.Objectives: In this context, we improved functionality of tragac...
Article
Full-text available
Green Analytical Chemistry advocates for the utilization of environmentally friendly chemicals and reagents, energy conservation in laboratory equipment, and the reduction of waste to a minimum. Recent developments in analysis involve the reduction in size of analytical instruments, the use of solventless or solvent-minimized extraction techniques,...
Article
Full-text available
Ecological issues are raised by analytical research methods that harm the environment, such as liberating dangerous solvents into the atmosphere. Sustainable analytical techniques should consider method performance, eco-friendliness, productivity, and practicality to reduce these difficulties. These consequences can be reduced by evaluating sustain...
Article
Full-text available
Background This study proposes a simple digital image colorimetric method using a smartphone for the quantitative analysis of isoniazid in pharmaceutical medications. The analytical methodology employed in this study involved the utilization of the reaction between isoniazid and FC reagent under alkaline conditions. The chemical reaction led to the...
Article
HPLC is one of the most widely used analytical method for determination of pharmaceuticals in pharmaceutical industry. Because of wide range availability of columns, it is difficult to choose the column while optimization and it consume lot of time. To reduce the time and solvent consumption for optimizing the column in HPLC method the best alterna...
Article
Full-text available
The objective of this study was to examine the impact of biologically produced CuO-NPs (Copper oxide nanoparticles) on the growth of bacterial strains. The physico-chemical properties of CuO-NPs were analyzed using a UV-Vis spectrophotometer, X-ray diffraction (XRD), field emission scanning electron microscope (FE-SEM), and energy-dispersive X-ray...
Article
Full-text available
CART cell therapy is becoming gamechanger in treating of various types of cancer. However, this treatment has produced extraordinary clinical responses in cancer patients, but the treatment expected and unexpected toxicities are generated. Avoiding the toxicity has become a crucial step in the thriving application of this happening technology. In t...
Article
Keloid or Che.loid, [kee-loid] Keloid are abnormal scars that, if not treated appropriately, can cause substantial emotional and physical distress in patients. Scars are prone to recurrence and rarely regress. They are unpleasant, can cause pain, itching, discomfort, and can have a negative impact on one's quality of life. Keloid development is inf...
Article
Full-text available
Cancer is now considered the number one leading cause of premature death in industrialized countries. Chemotherapy drugs are quite expensive and cause multiple side effects. Natural products have been studied in depth for their potential as anticancer agents because of their remarkable chemical variability. Among the various natural metabolites, fl...
Article
Full-text available
Substituted pyrazoles are one of the important classes of heterocyclic compounds because they can serve as unique and versatile pharmacophores in drug design and discovery. They are very well known for diversified biological activities like antibacterial, antifungal, anti-tuberculosis anti-inflammatory, antioxidant anticancer, analgesic, etc. As a...
Article
Full-text available
Narcolepsy is a rare chronic, debilitating sleep disease that is currently categorized as different types of CNS hypersomnia in narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). Narcolepsy type 1 (NT1) is narcolepsy with cataplexy caused by a selective loss of hypothalamic neurons that produce hypocretin, while NT2 is narcolepsy without cataplex...
Article
Full-text available
Lung, prostate, and stomach cancer are the most prevalent cancers among males. Breast, colon, and cervical cancer are the most prevalent cancers among women. The literature also shows that patients suffering from cancer are increasing constantly, and hence the number of different chemotherapy treatments administered is increasing. The main objectiv...
Article
Full-text available
Currently, gastro-retentive dosage forms achieved a remarkable position among the oral drug delivery systems. This is a broadly used technique to hold the drug delivery systems for a long duration in the gastro intestine (GI) region, slow drug delivery, and overcome other challenges related to typical oral delivery such as low bioavailability. The...
Article
Full-text available
Pyrazoles are biologically important derivatives for various pharmacological activities. The study aims to evaluate the potency of designed pyrazole derivatives for their anti-bacterial activity against the active site of bacterial DNA gyrase using autodock4.2.6. The three-dimensional crystal structure of the DNA gyrase (PDB Id: 4URM) was retrieved...
Article
Full-text available
A simple and precise liquid chromatography coupled with mass spectrometry LC-MS method was developed for determination and quantification of Drotaverine in human plasma and validated. The drug was separated by using liquid-liquid extraction (LLE) Method. A C18 column was employed for the separation of the drug on a gradient mode by using high-perfo...
Article
Full-text available
Background: A sensitive high-performance liquid chromatography coupled with mass spectrometry method was developed and validated for the quantification of amifampridine in human plasma. Methods: Following liquid-liquid extraction, the analyte and internal standard were separated using an isocratic mobile phase on a reverse phase C 18 column and ana...
Article
Full-text available
Background: A sensitive high-performance liquid chromatography (LC) coupled mass spectrometry (MS) method was developed and validated for the quantification of omadacycline in human plasma. Materials and Methods: Following liquid-liquid extraction, the analyte and internal standard were separated using an isocratic mobile phase on a reverse phase C...
Article
Full-text available
The chromatographic conditions were successfully developed for the separation of Levocetirizine and Candesartan cilexetil by using Inertsil-ODS C18 (250 x 4.6 mm, 5 μ), flow rate was 1 ml/min, mobile phase ratio was Methanol: Acetonitrile (90:10 v/v), detection wavelength was 230 nm. The Spectroscopic method was done in solvent using mobile phase a...
Article
Full-text available
The main objective of present research work is to formulate the floating tablets of atenolol using 3 2 factorial design. Atenolol, β-blocker belongs to Biopharmaceutical Classification System Class-III. The floating tablets of atenolol were prepared employing different concentrations of hydroxypropyl methylcellulose (HPMC) K15M and sodium bicarbona...
Article
Full-text available
The main objective of present investigation is to formulate the floating tablets of Ranitidine.HCl using 32 factorial design. Ranitidine.HCl, H2-receptor antagonist belongs to BCS Class-III. The Floating tablets of Ranitidine.HCl were prepared employing different concentrations of HPMCK4M and Guar Gum in different combinations as a release rate mod...
Article
Full-text available
A B S T R A C T The present study was undertaken to investigate the protective effect and possible mechanism of methananolic extract of Barleria Montana Nees (BM) on paracetamol indued rat. This respective activity was assessed through monitoring liver function tests through the measurement of triglycerides, cholesterol, total protein, total biliru...
Article
Full-text available
The need of anthelmintic drugs in the market is increasing day to day. The present study was designed to synthesize various veratraldehyde derivatives. The synthesized compounds were evaluated for anthelmintic activity. Streptomycin was used as standard drug for evaluation. The several veratraldehyde derivatives were synthesized on basis of two cla...
Conference Paper
Now a day treating infectious diseases had become a task because of the resistance developed by pathogenic microorganisms towards the synthetic antimicrobial agents. The only alternative for this is to use the natural compounds. But the natural compounds are having lesser potency and they can’t be used for treating complex infections. Vanillin is o...

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