Naga Lakshmi

SRI SIDDHARTHA INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE T BEGUR BANGALORE RURAL KARNATAKA INDIA · BIOCHEMISTRY

Parkinson’s disease (PD), a neurodegenerative disorder, is characterized by appearance of Lewy-body-like inclusions in Nigro-striatal terminals, which finally ends up with reactive gliosis and cell death. In its familial forms, a loss of normal function of α-synuclein, as well as toxic effects of its mutated form, finally leading on to oxidative st...

Parkinson's disease (PD) is an age-related neurodegenerative disorder that affects approximately 1 million persons in the United States. It is characterized by resting tremor, rigidity, bradykinesia, gait disturbance and postural instability. Its pathological features include degeneration of dopaminergic neurons in the substantia nigra pars compact...

Background and Aim: Non-communicable diseases (NCDs) such as coronary artery disease (CAD) and diabetes mellitus (DM) are assuming importance due to an accelerating rate of morbidity and mortality. The overall mortality from acute myocardial infarction in the diabetic population is reported to be 4-7 times higher. Modern laboratory diagnosis of car...

Parkinson's disease (PD) is an age-related neurodegenerative disorder that affects approximately 1 million persons in the United States. It is characterized by resting tremor, rigidity, bradykinesia, gait disturbance and postural instability. Its pathological features include degeneration of dopaminergic neurons in the substantia nigra pars compact...

Background and aim: Metabolic syndrome (MS) is a constellation of atherosclerotic risk factors and identifies patients who are at high risk for diabetes mellitus and cardiovascular disease (CVD). The interrelationship between gamma glutamyl transferase (GGT), obesity, and other metabolic disturbances raises the possibility that elevated GGT levels...

Gliomas are the most common subgroup of primary malignant brain tumors in adults, constituting >40% of all primary CNS neoplasms.

Introduction: β-thalassemia major is one of the most common hereditary hematologic disorders characterized by severely impaired β-globulin synthesis. Renal proximal tubular dysfunction may occur in children with β-thalassemia major without clinical manifestations of renal dysfunction or decrease in GFR. However, there is paucity of information abou...