Nadja Stöffler

Nadja Stöffler
German Cancer Research Center | DKFZ · Division of Epigenetics

About

3
Publications
606
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36
Citations
Citations since 2017
3 Research Items
36 Citations
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201720182019202020212022202305101520

Publications

Publications (3)
Article
Full-text available
X-linked Dystonia-Parkinsonism is a monogenic neurodegenerative disorder of the basal ganglia, which presents as a combination of hyperkinetic movements and parkinsonian features. The underlying genetic mechanism involves the insertion of a SINE-VNTR-Alu retrotransposon within the TAF1 gene. Interestingly, alterations of TAF1 have been involved in...
Article
Full-text available
Neuronal microexons represent the most highly conserved class of alternative splicing events and their timed expression shapes neuronal biology, including neuronal commitment and differentiation. The six-nt microexon 34ʹ is included in the neuronal form of TAF1 mRNA, which encodes the largest subunit of the basal transcription factor TFIID. In this...
Article
Full-text available
Metacaspase, as hypersensitive response (HR) executors, has been identified in many plant species. Previously, the entire gene family of metacaspase has been uncovered, but there are still questions that remain unclear regarding HR-regulating gene members. In this study, based on metacaspase expression during different grapevine genotypes interacti...

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Projects

Project (1)
Project
1.identify the metacaspase gene famlily in vitis 2.sceen positive candidate responsive to denfense related cell death (Hypersensitive Response) 3.dig out the function of MC,via gene expression, subcellular location, overexpressing,,etc