
Nadia VilahurEuropean Agency for Safety and Health at Work (EU-OSHA) · Prevention and Research Unit
Nadia Vilahur
PhD epidemiology
About
52
Publications
9,059
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1,533
Citations
Introduction
Additional affiliations
January 2015 - December 2016
WHO European Center for Environment and Health
Position
- Technical officer Air Quality
Description
- Expert in environmental epidemiology, supporting the development of the update of the Global WHO Air Quality Guidelines
July 2010 - July 2014
Publications
Publications (52)
Aim:
The placenta is an informative and easily available tissue for many epidemiological studies. We analyzed the extent to which storage delay affects DNA methylation.
Material & methods:
Biopsies from two placentas were sequentially stored at -80°C after standing at room temperature for 30 min, 1 h, 2 h, 6 h and 24 h. Global DNA methylation wa...
BACKGROUND: Fetal exposure to endocrine disrupting chemicals may increase the risk for adverse health effects at birth or later in life. OBJECTIVES: The objective of this study is to analyze the combined effect of xenoestrogens on reproductive and perinatal growth outcomes (child birthweight, early rapid growth and body mass index (BMI) at 14months...
Epigenetic changes may play a role in the occurrence of asthma-related phenotypes.
To identify epigenetic marks in terms of DNA methylation of asthma-related phenotypes in childhood, and to assess the effect of prenatal exposures and genetic variation on these epigenetic marks.
Data came from two cohorts embedded in the Infancia y Medio Ambiente (I...
Introduction: The European Agency for Safety and Health at Work(EU-OSHA) has coordinated a large survey – the Workers’ ExposureSurvey on cancer risk factors in Europe (WES).
Materials and Methods: WES provides exposure assessment toa selection of 24 cancer risk factors, including ionising radiationand ultraviolet (UV) radiation, both solar and art...
Introduction
The health and social care sector is one of the largest in Europe. The European Agency for Safety and Health at Work (EU-OSHA) is currently conducting a multiannual research overview on the sector, aiming at increasing knowledge on the specific risks faced by workers in the sector and on best prevention strategies.
Materials and Metho...
Introduction
The European Agency for Safety and Health at Work (EU-OSHA) has coordinated a large survey – the Workers’ Exposure Survey on cancer risk factors in Europe (WES).
Materials and Methods
WES provides exposure assessment to a selection of 24 cancer risk factors, including ionising radiation and ultraviolet (UV) radiation, both solar and a...
Introduction
The European Agency for Safety and Health at Work (EU-OSHA) has coordinated the development and implementation of a large survey – the Workers’ Exposure Survey on cancer risk factors in Europe (WES).
Materials and Methods
WES looks at how workers are exposed to a selection of 24 cancer risk factors relevant in the European context, in...
Introduction
The European Agency for Safety and Health at Work (EU-OSHA) has coordinated the development and implementation of a large survey, the Workers’ Exposure Survey on cancer risk factors in Europe (WES), in six European Union (EU) countries: Finland, France, Germany, Hungary, Ireland and Spain.
Materials and Methods
WES uses the Occupation...
Introduction
EU-OSHA has implemented the largest European survey to date to estimate worker’s exposure to known cancer risk factors.
Methods
WES is based on the Australian workplace exposures study (AWES) and has been thoroughly adapted to the European work context. It uses the occupational exposure assessment tool for epidemiological studies (Occ...
Introduction
The European Agency for Safety and Health at Work (EU-OSHA) started in 2020 the preparation of a new European exposure survey to cancer risks factors across occupations, based on the adaptation of the Australian Workplace Exposures Study (AWES). The survey will provide semi-quantitative information on current exposure and co-exposures...
Objectives:
Analytical frameworks are graphical representation of the key questions answered by a systematic review and can support the development of guideline recommendations. Our objectives were to a) conduct a systematic review to identify, describe and compare all analytical frameworks published as part of a systematic and guideline developme...
Introduction
With cancer accounting for an estimated 53% of all work-related deaths in the European Union, data on exposure to known cancer risk factors at work are essential to improve the safety and health of workers, support the evaluation of existing policies and foster a productive and sustainable economy.
Objective
Recognising the lack of ha...
Systematic reviews are powerful tools for drawing causal inference for evidence-based decision-making. Published systematic reviews and meta-analyses of environmental and occupational epidemiology studies have increased dramatically in recent years; however, the quality and utility of published reviews are variable. Most methodologies were adapted...
This report is an initiative of the Joint Research Centre (JRC), the science and knowledge service of the European Commission (EC), supported by the Commission’s Directorate-General for Regional and Urban Policy (DG REGIO). It highlights drivers shaping the urban future, identifying both the key challenges cities will have to address and the streng...
Background
An estimated 110 million workers are exposed to welding fumes worldwide. Welding fumes are classified by the International Agency for Research on Cancer as carcinogenic to humans (group 1), based on sufficient evidence of lung cancer from epidemiological studies.
Objective
To conduct a meta-analysis of case-control and cohort studies on...
The IARC Handbook of Cancer Prevention conduct evidence-based expert evaluations on the cancer preventive effects of interventions and strategies for primary and secondary prevention. In November 2017, 23 experts from 15 countries met at the International Agency for Research on Cancer in Lyon, France to evaluate different methods of screening for C...
Social inequalities in cancer are a global problem, as has been well documented inthe World Health Organization (WHO)/International Agency for Research onCancer (IARC) publication Social Inequalities and Cancer.1Inequalities in income,wealth, education, and power disproportionally impact the most disadvantagedindividuals, communities, and countries...
The International Agency for Research on Cancer concluded that screening for colorectal cancer with stool-based tests and with lower endoscopy (either colonoscopy or sigmoidoscopy) saves lives. Comparative effectiveness data were inconclusive.
Purpose: An estimated ~110 million workers are exposed to welding fumes worldwide.
Previously, classified by IARC as possibly carcinogenic to humans (Group 2B) in 1990, was
re-evaluated in 2017 and classified as carcinogenic to humans (Group 1), based on sufficient
evidence of lung cancer. To quantify the magnitude of effect, the WG conducted a met...
This document summarizes key WHO publications in the field of air quality and health since the 1950s, which led to the development of the series of WHO air quality guidelines. It outlines the evolution of the scientific evidence on the health effects of air pollution and of its interpretation, supporting policy-and other decision-makers in setting...
Background: We conducted an epigenome-wide association study (EWAS) of DNA methylation in placenta in relation to maternal tobacco smoking during pregnancy and examined whether smoking-induced changes lead to low birthweight.
Methods: DNA methylation in placenta was measured using the Illumina HumanMethylation450 BeadChip in 179 participants from...
Introduction: The placental methylome changes in response to in utero conditions. We conducted an epigenome-wide association study of DNA methylation in placenta in relation to maternal tobacco smoking in pregnancy, and examined whether smoking-induced changes lead to low birth weight in the offspring.
Methods: First, DNA methylation in placenta w...
Background:
In utero exposure to xenostrogens may modify the epigenome. We explored the association of prenatal exposure to mixtures of xenoestrogens and genome-wide placental DNA methylation.
Materials & methods:
Sex-specific associations between methylation changes in placental DNA by doubling the concentration of TEXB-alpha exposure were eval...
Smoking increases the risk of many diseases and could act through changes in DNA methylation patterns. The aims of this study were to determine the association between smoking and DNA methylation throughout the genome at cytosine-phosphate-guanine (CpG) site level and genomic regions. A discovery cross-sectional epigenome-wide association study nes...
Mitochondria are sensitive to environmental toxicants due to their lack of repair capacity. Changes in mitochondrial DNA (mtDNA) content may represent a biologically relevant intermediate outcome in mechanisms linking air pollution and fetal growth restriction.
We investigated whether placental mtDNA content is a possible mediator of the associatio...
Prenatal exposure to the highly toxic and common pollutant cadmium has been associated with adverse effects on child health and development. However, the underlying biological mechanisms of cadmium toxicity remain partially unsolved. Epigenetic disruption due to early cadmium exposure has gained attention as a plausible mode of action, since epi-ge...
Individuals born very preterm (before 33 weeks' gestation; VPT) are at risk of life-long, neurological impairments, behavioural and other health problems. It is not clear whether these neurodevelomental abnormalities originate prenatally, postnatally or a combination of both. Dermatoglyphics are stable ectodermal markers of neurodevelopmental disru...
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One of the main lines of our group focuses On the research Of genetic and biological risk factors involved in functional psychosis (schizophrenia and bipolar disorder). Our studies are based on case-control, family and twin designs and are conducted in close collaboration with clinical and basic research groups from other Spanish and European Insti...