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Introduction
Nadezhda Angelova currently works at the Department of Inorganic Chemistry, Sofia University "St. Kliment Ohridski". Nadezhda does research in Nanotechnology, Polymer Chemistry and Pharmacology. Their most recent publication is 'Iron(III) and aluminium(III) based mixed nanostructured hydroxyphosphates as potential vaccine adjuvants: Preparation and physicochemical characterization'.
Current institution
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September 2012 - February 2013
Publications
Publications (10)
Here we present data on the preparation and adsorption properties of mixed zinc-calcium phosphates in aqueous dispersions. The phosphates were prepared by co-precipitation from aqueous solutions followed by autoclaving. The effects of various Ca/Zn initial molar ratios and the type of Ca-and Zn-precursor salts (chlorides and acetates) on the struct...
Removal of heavy metals ions from water sources still represents a challenge and different materials are being developed in order to overcome it. Iron oxide nanomaterials receive a lot of attention because of their small size, high surface area, biocompatibility and low cost. However, most of the reported synthesis methods are multi-step and time-c...
This article presents the preparation and characterization of various calcium-magnesium phosphate suspensions with particular focus on nanostructured magnesium whitlockite as potential protein adsorbent. The phosphates were synthesized by precipitation from mixed Ca(II)/Mg(II) solutions with disodium hydrogen phosphate followed by thermal treatment...
Ferric phosphate has been proposed for vaccine adjuvant use and therefore studies on its preparation and physicochemical properties are highly required in order to achieve reproducibility of production and optimal adsorption capacity for protein antigens. Here, we report on the protein adsorption properties of nanostructured ferric phosphate adjuva...
This article describes part of the results obtained during the development of a new generation of vaccine adjuvants based on nanostructured hydroxyphosphates of tunable composition and physicochemical characteristics. Colloidal gels of ferric hydroxyphosphates of various iron/phosphate ratios were prepared by precipitation techniques, sterilized by...
Adjuvants are substances that, when combined with an antigen in a vaccine formulation, potentiate the immune response against that antigen. Aluminium hydroxyphosphate is among the currently used adjuvants in vaccines, while studies on its iron analogue, ferric hydroxyphosphate, are quite limited. In this article we report on the preparation and phy...
Copolymers of styrene and maleic acid of relatively low molecular weight possess a great potential for application as components of drug delivery systems, especially in cancer chemotherapy. The pioneering research in this area has been performed in the 1980s during the development of macromolecular complexes for selective drug delivery to solid tum...
