Myosotis Massidda

Myosotis Massidda
Università degli studi di Cagliari | UNICA · Department of Medical Science "Mario Aresu"

PhD

About

66
Publications
19,690
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
844
Citations
Citations since 2017
29 Research Items
710 Citations
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
Additional affiliations
January 2009 - present
Università degli studi di Cagliari
Position
  • Research Associate

Publications

Publications (66)
Article
Full-text available
Genetic components may play an important role in the regulation of nutrient and energy metabolism. In the presence of specific genetic variants, metabolic dysregulation may occur, especially in relation to the processes of digestion, assimilation, and the physiological utilization of nutrients supplied to the body, as well as the regulation of vari...
Article
The aim of this study was to translate, culturally adapt and validate an Italian version of the Athlete Fear Avoidance Questionnaire (AFAQ-I). We conducted a cross-sectional evaluation of the psychometric properties of the AFAQ-I in university athletes with musculoskeletal injuries, culturally adapting it in accordance with international standards....
Article
Full-text available
Background: To date, nearly 300 genetic markers were linked to endurance and power/strength traits. The current study aimed to compare genotype distributions and allele frequencies of the common polymorphisms: MCT1 rs1049434, NRF2 rs12594956, MYBPC3 rs1052373 and HFE rs1799945 in Polish elite athletes versus nonathletes. Methods: The study invol...
Article
Full-text available
The purpose of this study was to compare the frequency of COL1A1 rs1107946 polymorphism between sport climbers and controls from three ethnic groups (Japanese, Polish, and Russian) and investigate the effect of the COL1A1 rs1107946 polymorphism on the age-related decrease in flexibility in the general population. Study I consisted of 1929 healthy p...
Article
Full-text available
Background: To date, nearly 300 single-nucleotide polymorphisms (SNPs) associated with BMI, waist-to-hip ratio, and other adiposity traits have been identified by GWAS. With regards to IL10, at least 49 IL10-associated polymorphisms have been reported. However, little is known regarding the relationship between SNPs of the IL10 gene and the risk o...
Article
Full-text available
PurposeThe aim of this study is to investigate the influence of the MCT1 T1470A polymorphism (rs1049434) on repeated sprint ability (RSA) and lactate accumulation after RSA testing.Methods Twenty-six elite Italian male football players (age: 17.7 ± 0.78 years; height: 179.2 ± 7.40 cm; weight: 72.1 ± 5.38 kg) performed RSA testing (6 × 30-m sprints...
Article
Full-text available
This study aimed to investigate the ACTN3 R577X, ACE I/D, CKM rs8111989, and TRHR rs7832552 genotypes in climbers and controls in three ethnicities. The study consisted of 258 climbers (Japanese, n = 100; Polish, n = 128; Russian, n = 30) and 1151 controls (Japanese: n = 332, Polish: n = 635, Russian: n = 184). Genotyping results were analyzed usin...
Preprint
Full-text available
Background. The aim of this study was to translate, culturally adapt and validate an Italian version of the Athlete Fear Avoidance Questionnaire (AFAQ-I). Methods. We conducted a cross-sectional evaluation of the psychometric properties of the AFAQ-I in athletes with musculoskeletal injuries, culturally adapting it in accordance with international...
Article
Full-text available
The presented study showed the relationship between dopamine receptor gene polymorphism and personality traits in athletes training in martial arts. Behavioral modulation resulting from a balance of the neurotransmitters dopamine and norepinephrine to inactivation of the dorsolateral prefrontal cortex and dysregulation of various pathways involved...
Article
Full-text available
Athletic ability is influenced by several exogenous and endogenous factors including genetic component. Hundreds of gene variants have been proposed as potential genetic markers associated with fitness-related phenotypes as well as elite-level athletic performance. Among others, variants within the PPARA gene that code for the peroxisome proliferat...
Article
Full-text available
The functional FABP2 Ala54Thr polymorphism (rs1799883) is strongly associated with lipid and carbohydrate metabolism, although the function of its potential modifying effect on training-induced changes in obesity-related parameters is still unknown. The aim of the present study was to investigate the influence of the Ala54Thr polymorphism on post-t...
Article
Full-text available
Sport climbing will become an official event at the 2020 Tokyo Olympics; it is a popular wilderness sport among athletes and amateurs. Our previous study suggested that the T1470A polymorphism (rs1049434) of the monocarboxylate transporter 1 (MCT1) gene is associated with athletic performance and physiological phenotypes. The purpose of this study...
Article
Full-text available
Background: The aim of this study is to analyze the worldwide distribution of SNP rs4870723 in COL14A1 gene to check if there are significant genetic differences among different populations and to test if the gene is a trait under selection. Methods: Genomic DNA was extracted from 69 unrelated individuals from Sardinia and genotyped for SNP rs48...
Article
The aim of this meta-analysis was to aggregate data from studies investigating the risk factors associated with low back pain (LBP) in competitive gymnasts. Four databases were searched and studies reporting demographics, anthropometrics, functional, psychosocial and gymnastics-practice variables in competitive gymnasts with and without LBP were i...
Article
ACE I/D polymorphism has been recently associated with the susceptibility to inflammation and muscle damage after exercise. The aim of this study was to understand the association between the ACE I/D polymorphism and muscle injuries in a large cohort of elite football players from two different countries. Seven hundred and ten male elite football p...
Chapter
Compared to sprint/power and endurance sports, the genetic contribution to success in sports that require a mixture of anaerobic and aerobic qualities has received relatively limited attention. This chapter evaluates research findings on the potential genetic variants influencing the team sports athletic status and the key factors for team sports p...
Article
The aim of this study was to investigate the association between the MCT1 (monocarboxylate transporter 1) A1470T polymorphism and positional roles in a large cohort of professional football players from five different countries. We compared genotype distributions of the MCT1 A1470T polymorphism between football players (n=694) and non-athlete contr...
Article
A common missense mutation (1470T > A) in gene SLC16A1 responsible for an amino acid substitution in protein MCT1 has been associated with differential lactate transport and hence, differences in physical performance and muscle injuries in relation to physical exercise. This study describes, for the first time, the worldwide variation of MCT1 varia...
Article
Full-text available
Background Studies investigating associations between ACTN3 R577X and ACE I/D genotypes and endurance athletic status have been limited by small sample sizes from mixed sport disciplines and lack quantitative measures of performance. Aim: To examine the association between ACTN3 R577X and ACE I/D genotypes and best personal running times in a large...
Article
Objective: The ACTN3 R577X gene variant results in the absence of the α-actinin-3 protein in ∼18% of humans worldwide and has been associated with athletic performance and increased susceptibility to eccentric muscle damage. The aim of this study was to investigate the association between ACTN3 R577X variant and indirect muscle disorders/injuries...
Article
Full-text available
Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. To investigate the genetic determinants of variation in grip strength, we perform a large-scale genetic discovery analysis in a combined sample of 195,180 individuals and identify 16 loci associated wi...
Article
Full-text available
This research has been conducted using the UK Biobank Resource. The Fenland Study is supported by the UK Medical Research Council (MRC) (MC_UU_12015/1; MC_UU_12015/2; MC_UU_12015/3). EPIC-Norfolk is supported by the MRC (G401527, G1000143) and Cancer Research UK (A8257). The HCS is gratefully supported by the University of Newcastle (Australia) and...
Article
Full-text available
The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) A1298C polymorphic variant is a candidate to explain the individual differences in trainability and response to exercise training. Therefore, the aim of the study was to verify whether the A1298C polymorphism influenced the aerobic and anaerobic performance as well as body and mass compositi...
Article
Full-text available
Skeletal muscle strength and mass, major contributors to sprint/power athletic performance, are influenced by genetics. However, to date, only a handful of genetic variants have been associated with sprint/power performance. The ACVR1B A allele (rs rs2854464) has previously been associated with increased muscle-strength in non-athletic cohort. Howe...
Data
Genotype distributions at rs2854464 in Italian, Polish and Russian samples. C = controls; E = endurance athletes; S/P = sprint/power athletes; All = all athletes. (TIF)
Data
The full dataset used in this study. (XLSX)
Article
Full-text available
Background To date, studies investigating the association between ACTN3 R577X and ACE I/D gene variants and elite sprint/power performance have been limited by small cohorts from mixed sport disciplines, without quantitative measures of performance. Aim: To examine the association between these variants and sprint time in elite athletes. Methods We...
Article
Full-text available
Abstract Background: The aim of this study was to investigate the association between MCT1 rs1049434 polymorphism and indirect muscle injuries in elite football players. One hundred and seventy-three male elite Italian football players (age = 19.2 ± 5.3 years) were recruited from a first-league football club participating at the Official National I...
Article
Full-text available
The aim of our study was to determine if the Sardinian folk dance ballu sardu (BS) can be identified as an effective workout regimen in terms of its exercise intensity (EI) and energy expenditure (EE) and if people who perform BS fulfill the recommendations of the American College of Sports Medicine on the prescription of exercise in healthy subjec...
Article
of the study. The aim of this study was to investigate the association between the MCT1 A1470T polymorphism and fat-free mass in young Italian elite soccer players. Participants were 128 Italian male soccer players. Fat-free mass was estimated for each of the soccer player using age- and gender-specific formulas with plicometry. Genotyping for the...
Article
Full-text available
Aim: Significant levels of physical activity (PA) have benefit in reducing chronic diseases in the general adults, but little is known on the association between health-related quality of life (HRQoL) and PA levels among young population. This study aims to investigate the association between different levels of PA and HRQoL in a random sample of...
Article
Full-text available
The aim of the present study was to investigate the association between vitamin D receptor (VDR) gene polymorphisms and musculoskeletal injury (MI) in elite football players. In total, 54 male professional football players were recruited from an official Italian professional championship team between 2009 and 2013. The cohort was genotyped for the...
Article
Full-text available
The aim of the present study was to investigate the association between vitamin D receptor (VDR) gene polymorphisms and musculoskeletal injury (MI) in elite football players. In total, 54 male professional football players were recruited from an official Italian professional championship team between 2009 and 2013. The cohort was genotyped for the...
Article
Full-text available
Background: The ACTN3 gene may influence performance in team sports, in which sprint action and high-speed movements, regulated by the anaerobic energy system, are crucial to the ultimate success of a match. The aim of this study was to determine the association between the ACTN3 R577X (rs1815739) polymorphism and elite team sport athletic status i...
Article
Full-text available
Background: The ACTN3 gene may influence performance in team sports, in which sprint action and high-speed movements, regulated by the anaerobic energy system, are crucial to the ultimate success of a match. The aim of this study was to determine the association between the ACTN3 R577X (rs1815739) polymorphism and elite team sport athletic status i...
Article
Full-text available
Purpose: Much evidence has been provided to support the relationship between single nucleotide polymorphisms and athletic performance and the susceptibility to develop injuries participating in sports. We report an up-to-date review of the genetic factors involved in artistic gymnastics. Methods: We conducted a search in PubMed using specific keywo...
Article
AIM: The aim of this study was to investigate whether COL5A1 rs12722 polymorphism is associated with musculoskeletal injuries in elite soccer players. METHODS: Fifty--four male professional soccer players of European origin (25.9±4.3 years) were recruited from a team participating at the Official Italian Professional Championship during four consec...
Article
Full-text available
Introduction: Skeletal muscle injuries sustained during sport and their subsequent functional recoveries seem to be influenced by interactions between environmental stimuli (training, overload/overtraining, wrong techniques) and specific genotypes. Variations in DNA sequences in specific genes have been associated with specific phenotypes involved...
Article
Full-text available
The somatotyping method is especially helpful in sports in which the body could directly influence the biomechanics of movements and the performance's results. The purpose of this study was to determine the somatotype of elite Italian gymnasts and to compare it in terms of competition levels. The sample comprised 64 elite gymnasts (42 females (F),...
Article
Purpose: The aim of the current study was to construct a genetic model with a new algorithm for predicting athletic-performance variability based on genetic variations. Methods: The influence of 6 polymorphisms (ACE, ACTN-3, BDKRB2, VDR-ApaI, VDR-BsmI, and VDR-FokI) on vertical jump was studied in top-level male Italian soccer players (n = 90)....
Article
Full-text available
The ACE I/D and the ACTN-3 R577X polymorphisms are the most studied genes associated with elite athlete status, even if this association has been often conflicting. The aim of the present study was to investigate the association between the ACE and the ACTN3 genotypes and elite performance in Italian male athletes. The ACTN-3 R577X and the ACE I/D...
Article
Full-text available
Introduction. Several studies have shown that high-intensity artistic gymnastics training combined with low-calorie intake, could alter the normal growth patterns and maturation of gymnasts. However, it has not been yet demonstrated a cause-effect relationship between the high artistic gymnastics training workout and the alteration of growth. Objec...
Article
Abstract Scores in artistic gymnastics are subject to changes in the rules that occur each Olympic cycle as outlined in the Code of Points, because rules influence the composition of routines and therefore performance. The aim of this study was to identify the most important routine apparatus for success in a World competition. The data were the of...
Article
The aim of the present paper was to investigate the relationships between polymorphisms in ACTN3, ACE and BDKRB2 genes, soccer performance, and explosive leg-muscle strength in Italian soccer players. We examined 42 top-level Italian soccer players (S) and 106 sedentary healthy Italians, as a control group (C). χ2 test was used to look for the diff...
Article
Full-text available
The aims of this study were to estimate the energy expenditure (EE) and the intensity of physical activity (PA) during a competitive simulation of Latin American dancing and to evaluate the differences in PA and EE values between the sexes, between different dance types, and between the various phases of the competition. Ten Italian dancers (five c...
Article
The angiotensin converting enzyme (ACE) polymorphism is the most studied genetic marker in the field of human performance. There is a continuing debate in the literature regarding the possible association of ACE genotypes and elite athletic status. In fact, despite recent studies having identified no significant associations in athletes from mixed...
Article
Full-text available
Aim. The purpose of this study was to verify the association between the ACE l/D polymorphism and elite athletes status in Italian soccer players. Methods. DNA was extracted from each participant using buccal swab. We determined the genotype and allele frequencies of ACE l/D polymorphism in a group of 26 top-level male soccer players. Their results...
Article
Full-text available
This methodological and descriptive work highlights how the contri-bution of the Specialists in Adapted Physical Activity (APA) is important in an in-tervention composed of different skills and disciplinary approaches, and how their professional specificity can play a determining role to achieve the best results for the complete recovery of athlete...
Article
The ACTN3 (R577X) gene encodes for a structural protein that is exclusively expressed in the Z-disc of type II muscle fibers. Homozygosis (577XX) for the stop codon in the ACTN3 polymorphism results in alpha-actinin-3 complete deficiency. Previous studies have shown low frequencies of the ACTN3 XX genotype in elite sprinters compared to the general...
Conference Paper
Full-text available
Sino alla metà del secolo scorso la maggior parte degli studi sul successo raggiunto nello sport erano basati unicamente sulla morfo-logia corporea. Nell'ultima decade le ricerche si sono focalizzate sul-lo studio delle varianti geniche sarebbero predisponenti per una buo-na performance sportiva. In realtà l'esercizio fisico è il risultato di una c...
Conference Paper
Full-text available
Lo scopo del presente studio è stato quello di individuare le variabili morfometriche correlate con la performance al volteggio delle ginnaste italiane d’elite e delineare al contempo un modello di regressione che includesse le variabili antropometriche potenzialmente in grado di predire il successo della performance ginnica per questa specialità....
Conference Paper
Full-text available
Questa breve rassegna dei lavori più recenti che si occupano della struttura fisica delle atlete della ginnastica artistica ha cercato, a partire da alcune caratteristiche di ginnaste italiane di alto livello, di estrapola-re indicazioni circa i caratteri somatometrici che possono essere utili ai fini della predizione del talento nell'ambito della...
Article
Full-text available
Una vasta letteratura è stata prodotta nel tentativo di individuare e di descrivere quali fossero nelle varie discipline sportive le caratteristiche morfologiche, antropometriche, fisiologiche e funzionali degli atleti che hanno raggiunto alti livelli nelle gare agonistiche. Negli ultimi anni la ricerca si è avviata verso l'analisi dei legami esist...

Network

Cited By