Mvuwo Phophi TshavhungweUniversity of Cape Town | UCT · Division of Neurosurgery
Mvuwo Phophi Tshavhungwe
About
3
Publications
207
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
6
Citations
Citations since 2017
Introduction
My research experience has crossed sub-disciplines within the Medical Sciences with a common thread of TB research. I am currently a PhD candidate, working on a research project titled, Drug Recovery in Paediatric Tuberculous Meningitis. My research interests include but not limited to paediatric tuberculous meningitis and neuropharmacology.
Education
June 2013 - March 2016
January 2007 - December 2011
Publications
Publications (3)
Limited knowledge is available on the pharmacokinetics of rifampicin in children with tuberculous meningitis (TBM) and its penetration into brain tissue, which is the site of infection. In this analysis, we characterize the distribution of rifampicin in cerebrospinal fluid (CSF), lumbar (LCSF) and ventricular (VCSF), and brain extracellular fluid (...
Purpose
A better understanding of the complex pathophysiology of traumatic brain injury (TBI) is needed to improve our current therapies. Cerebral microdialysis (CMD) is an advanced method to monitor the brain, but little is known about its parameters in children. Brain glycerol, one of the CMD variables, is an essential component of the phospholip...
Tuberculous meningitis (TBM) is the most fatal form of tuberculosis and frequently occurs in children. The inflammatory process initiates secondary brain injury processes that lead to death and disability. Much remains unknown about this cerebral inflammatory process, largely because of the difficulty in studying the brain. To date, studies have ty...
