Muzaffer Seyhan Cikman

Muzaffer Seyhan Cikman
Zeynep Kamil Women's and Children's Disease Training and Research Hospital · Gynocologic Oncology

About

32
Publications
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166
Citations
Introduction
Skills and Expertise

Publications

Publications (32)
Article
Full-text available
Objective: In this study, we evaluated the effect of depression, anxiety, and stress on pain perception during colposcopy. Material and methods: This study was performed at the gynecologic oncology department of Lutfi Kirdar Kartal Education and Research Hospital in Istanbul, Turkey between September 2017 and January 2018. After taking informed con...
Article
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To evaluate whether mirtazapine and mesna have protective effects on cisplatin-induced ovarian injury. A total of 32 female Wistar Albino rats were divided into 4 groups (8 rats per group) and included in the study. No medication was administered to the first group; only intervention was that their ovaries were removed and anti-mullerian hormone (A...
Article
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Objective: This study aimed to evaluate any potential associations between uterine leiomyomas and endometrial cancer. Materials and Methods: This is a retrospective study of 153 female patients who have been operated because of endometrial carcinoma in our hospital between 2012 and 2017. Data were collected from hospital records. Study participant...
Article
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Introduction:In our study we aimed to observe the protective effects of imatinib and ginkgo biloba (GB) on cisplatin (CP)- induced ovarian damage in rats.Methods:Thirty-two female rats were included and assigned to four groups. Group 1 had no medication. Their ovaries were removed for examination and the serum Anti-Mullerian hormone (AMH) levels we...
Article
To determine the possible detrimental effects of multiple methotrexate doses has on the ovarian reserve and to determine the beneficial effects of dehydroepiandrosterone supplementation. The rats (n:24) divided into three groups; Group 1: control group, Group 2: dehydroepiandrosterone and methotrexate group (6mg/kg dehydroepiandrosterone dissolved...
Article
Full-text available
OBJECTIVE: There are many predisposing factors associated with vaginismus, but there is lack of data in the literature regarding which and how of these factors influence the success rate of treatment. Our aim is to investigate the effects of factors that are considered as predisposing factors for vaginismus on treatment prognosis and success rate,...
Article
Full-text available
To determine the possible detrimental effects of multiple methotrexate doses has on the ovarian reserve and to determine the beneficial effects of dehydroepiandrosterone supplementation. The rats (n:24) divided into three groups; Group 1: control group, Group 2: dehydroepiandrosterone and methotrexate group (6mg/kg dehydroepiandrosterone dissolved...
Article
Full-text available
Objective: In this study, the effectiveness of caffeic acid phenethyl ester (CAPE) and Dehydroepiandrosterone (DHEA) in preventing ischemia reperfusion injury associated with ovarian torsion have been investigated. Materials and Methods: Twenty four adult female Wistar Albino rats were randomly divided into four groups. Ovaries were not twisted, an...
Article
Full-text available
To investigate whether Dehydroepiandrosterone (DHEA) and Caffeic acid phenethyl ester (CAPE) had any preventive effect against the ovarian damage caused by cisplatin (CP) (cis-diamminedichloroplatinum) in rats. On the first day ovaries were removed, Anti-Müllerian hormone (AMH) was measured (Group1, n:6), in the other groups 7.5 mg/kg cisplatin was...
Preprint
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Our aim was to investigate the effect of platelet-rich plasma (PRP) derivatives, which can be produced from the patient’s own blood and have minimal side effects, on endometriosis. To the best of our knowledge, this is the first study in the literature that studies the relationship between PRP and endometriosis. Endometriosis foci were created in t...
Article
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Objectives: The aim of this study was to compare the effects of sildenafil, vardenafil and tadalafil in treatment for ischemia/reperfusion injury which is created experimentally in rat ovaries. Material and methods: For this study, 30 female Wistar albino rats were used, and the rats were separated randomly intofive groups consisting of six rats...
Article
Amaç: Benign nedenlerle yapılan total laparoskopik histerektomiden (TLH) sonra dren kullanımı rutin bir uygulama olmayıp tartışılan bir konudur. Amacımız dren kullanımının hasta kan değerlerine, postoperatif takip parametrelerine ve taburcu olma sürelerine etkisini araştırmaktır.Gereç ve Yöntemler: Kartal Dr. Lütfi Kırdar Eğitim ve Araştırma Hastan...
Article
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GİRİŞ ve AMAÇ: Bu çalışma, medikal tedavi verilen ektopik gebeliklerde başlangıç B-hCG değeri ve 4.gün B-hCG değerindeki değişikliğe göre başarı durumunu öngörmeyi amaçlamıştır.YÖNTEM ve GEREÇLER: Çalışmada 2009-2017 yılları arasında Kartal Dr. Lütfi Kırdar Eğitim ve Araştırma Hastanesinde tek doz methotrexate ile tedavi edilen ektopik gebeler retr...
Conference Paper
Full-text available
Introduction: The aim of our study is to invastlgate sexuaI functions in pregnancy and how these functions change according to trlmesters. Methods: Pregnant women (n:324) between the ages of 18-45 who were admitted to the outpatient clinic of the Obstetrics and Gynecology Clinic of Research Hospital were included in to the study. Pregnant participa...
Article
AMAÇ: Endometrial poliplerin patogenezi halen tam olarak bilinmemektedir. Bu araştırmada amacımız endometrial poliplerdeki steroid reseptörlerini incelemektir.YÖNTEM: Bu araştırmada Şubat 2008 ile Aralık 2011 tarihleri arasında hastanemizde histeroskopik polipektomi yapılan 28 hastanın poliplerine ve sağlam endometrium dokularına ait östrojen ve pr...
Article
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Amaç: Bu çalışmanın amacı, vajinal doğum sonrası plasentanın kendiliğinden ayrılma zamanını ve bu süreyi etkileyen faktörleri belirlemektir.Yöntem: Çalışmamıza İstanbul Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum kliniğine 01.03.2016-01.01.2017 tarihleri arasında vajinal doğum için başvuran 198 hasta dahil edil...
Article
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Letter to the Editor Dear Editor, We have read the article entitled ‘’Immature Teratoma with Extra-Ovarian Deposits of Mature Teratoma –Case Report and Review of the Literature’’ by Haran G. et al. that appeared in the first issue of the volume 3 of the ‘’Austin J Med Oncol’’ in 2016, with great interest. We appreciate the writers and those who con...
Article
Full-text available
INTRODUCTION[|]The aim of this study was to evaluate depression, anxiety, loneliness, and the effects of social support in infertile women in Turkey.[¤]METHODS[|]A total of 140 patients who presented at the infertility clinic between June 2012 and December 2012 were included in the study. All of the participants completed the Hamilton Anxiety Ratin...
Article
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Objectives: To compare the effects of topical silicone gel and corticosteroid cream for preventing hypertrophic scar and keloid formation following Pfannenstiel incisions. Material and methods: Fifty patients operated for benign gynecological diseases through primary Pfannenstiel incision were included. The wounds were randomly allocated to the...
Article
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Objective The aim of the present study was to compare female sexual function between women who underwent conventional abdominal or laparoscopic hysterectomy. Materials and Methods Seventy-seven women who were scheduled to undergo hysterectomy without oophorectomy for benign gynecologic conditions were included in the study. The women were assigned...
Poster
Objective: Gestational diabetes mellitus (GDM) is a multifactorial disorder with environmental factors and genetic modifiers. IGF2BP2 gene polymorphisms are shown to be involved in T2DM and diabetic nephropathy. Here, we aimed to document the association between IGF2BP2 gene polymorphism and GDM to understand the pathogenesis of GDM. Design: Matche...
Article
Objective: The impact of simple and radical hysterectomy on all aspects of pelvic floor dysfunctions was evaluated in current study. Study design: This retrospective cohort study included 142 patients; 58 women (40.8%) who have undergone simple, 41 (28.8%) radical hysterectomy, and 43 (30.2%) women without any surgical intervention to serve as t...
Article
Full-text available
The aim of this study was to assess the predictive value of neutrophil/lymphocyte and platelet/lymphocyte ratios for borderline, malignant ovarian tumors, and borderline cases with microinvasion. Totally 275 women with sonographically detected ovarian tumor were enrolled for this study. All subjects underwent gynecological surgery via endoscopic or...
Article
Study objective: To compare adhesion formation and histological features of peritoneal closure and nonclosure over an intra-abdominally placed barbed suture. Design: Single-blind randomized controlled trial (Canadian Task Force Classification I). Setting: Certified animal research facility. Subjects: Eight nonpregnant rats. Interventions:...
Article
Full-text available
Purpose: To determine whether inherited thrombophilia affects components of second trimester combined aneuploidy screening test. Methods: A case-control study was performed between 1 December 2010 and 1 February 2012, at a tertiary referral hospital. Singleton pregnancies with inherited thrombophilia that underwent second trimester (16-19(+6) we...
Poster
Objective: Gestational diabetes mellitus (GDM) is the consequence of increased insulin resistance during pregnancy in predisposed individuals who already have impaired insulin secretion due to beta-cell dysfunction as in maturity onset diabetes of young (MODY) cases. Here we aimed to document the association between MODY subtypes and GDM to underst...

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