Mutlu Özcan

Mutlu Özcan
University of Zurich | UZH

DDS, DMD, PhD

About

741
Publications
292,214
Reads
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18,399
Citations
Additional affiliations
January 2009 - December 2011
Universität Zürich
January 2009 - December 2011
University of Groningen
Position
  • Universitair Medisch Centrum Groningen
January 2007 - December 2012
São Paulo State University
Position
  • Universidade Estadual Paulista

Publications

Publications (741)
Article
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Statement of problem Even though polyetheretherketone (PEEK) has become popular for various prosthetic indications, a standard adhesive protocol to bond the PEEK to titanium bases has not been yet established. How the heat-pressing technique performs in this respect is also not clear. Purpose The purpose of this in vitro study was to investigate t...
Article
Statement of problem Additive manufacturing procedures for fabricating interim restorations include rinsing postprocessing procedures. However, the impact of different rinsing solutions and times on flexural strength is unknown. Purpose The purpose of this in vitro study was to assess the influence of the rinsing solutions and duration, as well as...
Article
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Objectives This study evaluated the surface integrity of two types of diamond burs and their effect on the roughness of different CAD/CAM materials. Materials and methods CAD/CAM materials, Vita Mark II (VM), IPS e.max CAD (EM), Celtra Duo (CD), G-Ceram (GC), and Lava Ultimate (LU) blocks were milled with CEREC MCXL. Five pairs of pointed cylinder...
Article
Purpose: To identify the most effective cleaning method for saliva-contaminated zirconia surface before adhesive cementation through a systematic review and meta-analysis. Materials and methods: PubMed, Scopus, and Web of Science databases were searched to select in vitro studies published through October 2021. Studies that did not perform aging...
Article
This clinical study evaluated the survival of monolithic lithium disilicate (ML) (IPS Emax, Ivoclar Vivadent) restorations bonded to complete-arch CAD/CAM made titanium or zirconia frameworks. Between August 2007 and December 2009, 15 patients (7 female, 8 male; mean age: 56.8 years old) received 30 implant-supported screw-retained rehabilitations...
Article
This study evaluated the clinical performance of implant supported, extra-orally cemented, monolithic zirconia crowns after a follow-up to 18 months. Thirty-one patients with 50 posterior dental implants were consecutively selected for this study. A total of 50 crowns were cemented onto titanium abutments extra-orally and then screwed to the implan...
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Purpose of Review Graphene is introduced in dentistry as a material to be used in the fabrication or coating of dental implants due to its biocompatibility, ability to physically interact with biomolecules and very high surface area. This review highlights the current knowledge on the general properties of graphene, potential benefits especially wh...
Article
Although the effects of different intraoral scanners, model scanners, and CAM units on the marginal and internal fitting of restorations have been investigated, the effects of CAD software in particular has not been evaluated. The marginal and internal fit of indirect restorations may vary according to the CAD software used, even when using the sam...
Article
Purpose/aim: To evaluate the effect of different veneering liquids used for modeling on microhardness, fracture toughness and biaxial flexural strength of a glass-veneering ceramic. Material and methods: The manufacturer recommended modeling liquid (ML), distilled water (DW), isopropyl alcohol (IA), 0.5% (P05), 1% (P1), and 2% (P2) polyethylene...
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Objective : The study aimed to quantitatively evaluate the elution of methylmethacrylate from CAD-CAM manufactured removable complete dentures (RCDs) using high performance liquid chromatography (HPLC). Methods: Thirty-two RCDs were manufactured following either the CNC-milling (Milled: n=8) or the 3D-printing (n=24) protocols. The 3D-printed dent...
Article
Purpose: This double-blind randomized clinical trial (RCT) aimed to evaluate the 2-year survival rates of endocrowns and partial coverage ceramic restorations (PCCR) with fiber posts. Material and methods: Forty (40) participants fulfilled the elegibility criteria, and they were randomly allocated in 2 groups: Endocrown or PCCR+post. The surviva...
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There is limited information on the effect of melatonin on the cytotoxicity of dental materials. The study evaluated the cytotoxic effects of heat- and auto-polymerized acrylic resin, particulate filler composite resin and a thermoplastic material on L-929 fibroblast cell viability at different incubation periods in artificial saliva without and wi...
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Additive manufacturing enables the realization of the macro- and microarchitecture of bone substitutes. The macroarchitecture is determined by the bone defect and its shape makes the implant patient specific. The preset distribution of the 3D-printed material in the macroarchitecture defines the microarchitecture. At the lower scale, the nanoarchit...
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This double-blinded and split-mouth design, randomized feasibility study aimed to assess the efficacy of prophylactic and therapeutic use of a new age NitrAdineTM-based brushing solution (PerioTabs®) on the clinical parameters before and after periodontal therapy. Four subjects were randomly assigned to two treatment groups according to periodontal...
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The aim of this work was to perform an integrative literature review on the influence of laser irradiation on zirconia implants to enhance surface topographic aspects and the biological response for osseointegration. An electronic search was carried out on the PubMed database using the following search terms: “zirconia” AND “laser” AND “surface mod...
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Purpose. To evaluate the chemical composition, flexural strength, and Weibull characteristics of milled and lithography-based additively manufactured (AM) zirconia. Materials and Methods. A virtual design of a bar (25x4x2 mm) was completed using a software program. The standard tessellation language file was used to manufacture all the specimens:...
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Background: Burning mouth syndrome (BMS) is a non-neuropathic chronic orofacial pain condition, characterized by the presence of burning/warm sensation without specific mucosal lesions. Objective: The aim of the present clinical case report is to describe the positive outcome of dental treatment of a patient with BMS and followed up for 25 years. D...
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This paper assesses the effect of cement type and cement preheating on the marginal and internal fit of lithium disilicate single crown. Methods: 40 maxillary premolars were selected, restored with lithium disilicate single crowns. Teeth were randomly assigned into four groups (n = 10) based on cement type (Panavia SA or LinkForce) and preheating t...
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Background Endodontically treated teeth usually can reveal an extensive loss of dental structure and require the use of intraradicular posts to provide adequate support and retention. Retention of the post depends on the surface treatment of the endodontic post itself and on the root canal dentin as well as on the type of resin-matrix cement.Purpos...
Article
Aim: To evaluate the fracture resistance of three-unit fixed dental prosthesis (FDP) made of composite, high-density polymers (HDP), fiber-reinforced composite (FRC), and metal-ceramic (MC) using different fabrication methods. Materials and methods: A typodont model was prepared to receive a three-unit FDP replacing a missing second maxillary pr...
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In the current study, we evaluated the effects of heat treatment (by Er:YAG or furnace) and various surface treatments on the microtensile bond strength (μTBS) of silanized lithium disilicate ceramic. Seventy lithium disilicate (IPS e. max Press; Ivoclar Vivadent) and composite resin (Tetric N-Ceram; Ivoclar Vivadent) blocks were made and distribut...
Article
Objective Rehabilitation of endodontically treated premolars with extensive coronal destruction through endocrown approach remains a controversial topic in reconstructive dentistry. There is no clear consensus in the literature which endocrown design with which material is the most effective restoration option for severely-destructed endodontically...
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Statement of problem High-level evidence concerning the restoration of endodontically treated posterior teeth by means of direct composite resin or indirect restorations is lacking. Purpose The purpose of this systematic review and meta-analysis was to analyze the current literature on the direct and indirect restoration of endodontically treated...
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This study evaluated the effect of clinical and patient-related factors on marginal bone loss. The sample was composed of individuals who were treated at two dental schools in southern Brazil. The variables evaluated were divided into individual (age, sex, diabetes, hypertension and antihypertensive use), and implant levels (arch, position, brand,...
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This study aimed to assess bioglass sintering to a zirconia core on surface properties and bonding strength to resin cement. Zirconia specimens were divided into four groups: G I: sintered; G II: bioglass modified zirconia (a bioglass slurry was sintered with zirconia at 1550 °C); G III: sandblasted using 50 μm Al2O3 particles; and G IV: Z-prime pl...
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The main aim of this study was to perform an integrative review on the release of bisphenol A (BPA) from resin‐matrix composites and potential toxic effects. A bibliographic search was performed on the PubMed platform using the following keywords: “Bisphenol A" OR “BPA” AND “resin composite” OR “composite resin” AND “toxicity” OR “cytotoxicity” OR...
Article
Chipping remains a big challenge during the clinical application of glass ceramics in dentistry. The fabrication procedure used affects the mechanical properties of dental feldspathic porcelain and is associated with technical failures. This study aimed to compare the effect of the use of manufacturers’ liquids versus H2O on the flexural strength o...
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Objectives: This cross-sectional study aimed to evaluate the frequency and risk factors associated with cusp fractures in posterior permanent teeth. Methods: Patients presented cusp fractures on posterior permanent teeth, clinically assessed in up to 7 days after the event, and requesting dental treatment at two public services were included in thi...
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Objective The aim of this study was to perform an integrative review on the layer thickness and microstructure of resin-matrix cements around custom-made or standard teeth root intracanal posts. Materials and methods An electronic search was conducted on the PubMed using a combination of the following scientific terms: intraradicular post, root in...
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This paper assesses the impact of preheating of adhesive cement on the fracture resistance of lithium disilicate and zirconia restorations. Methods: A total of 80 human maxillary premolar teeth were assigned into 8 groups (n = 10) according to material type (either lithium disilicate or zirconia) and type of resin cement (either LinkForce or Panavi...
Article
The aim of this study was to evaluate the effect of the type of preheated resin composite on the microtensile bond strength (µTBS) between dentin and feldspathic ceramic inlays. Thirty healthy human premolars received inlay preparations for feldspathic ceramic restorations and were then divided into three treatment groups according to the luting ag...
Article
Evaluate the influence of cleaning protocols on vitrification patterns, contact angles, and bond strength between zirconia and resin cement. 48 zirconia discs were sectioned, polished, and sintered (15 × 2 mm). The discs were randomized into four groups according to the zirconia cleaning protocol (n = 12), following: CJ (positive control)-sandblast...
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The aim of this work was to perform a short scoping review on the degradation of tooth occlusal fissure and pit sealants by wear and corrosion processes occurring in the oral cavity or in simulated saliva solutions. A Medline search was conducted for related scientific articles published within the last twenty years reporting the wear rate and corr...
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The aim of this study was to perform an integrative systematic review on the damage of dental resin-matrix composite and amalgam surfaces after exposure to bleaching agents composed of hydrogen or urea (carbamide) peroxide. An electronic search on PubMed was carried out using the following selected terms: amalgam” OR “resin composite” AND “bleachin...
Article
Objective To date, there is no clear consensus in the literature which endocrown design with which material is the most effective treatment option to restore endodontically treated maxillary premolars with extensive loss of tooth structure. The aim of this study was to evaluate the stress distribution pattern and failure probability of maxillary fi...
Article
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Objective To evaluate the effect of low-level laser therapy (LLLT) on pain intensity (PI) and chewing performance (CP) in systemic lupus erythematosus (SLE) patients with myogenic temporomandibular disorder (TMD). Methods Ninety-one patients were randomly allocated to three groups: Group L (intervention), Group P (placebo), and Group C (control)....
Article
Aim: 3D face impression techniques have been defined to eliminate the disadvantages of conventional impression methods. The aim of the present study was to evaluate and compare the accuracy of a digital technique using a novel 3D camera in relation to a conventional impression technique. Materials and methods: Ten prefabricated polystyrene head...
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Objectives: This study evaluated the biocompatibility, mechanical properties, and surface roughness of CAD-CAM milled and rapidly-prototyped/3D-printed resins. Methods: Six groups of resin specimens were prepared, milled-base (MB), milled-tooth shade (MT), printed-tooth shade (PT), printed-base with manufacturer-recommended 3D-printer (PB1), printe...
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Objectives: This review compared the differences between Computer-aided design- computer-aided manufacturing (CAD-CAM) and conventionally manufactured removable complete dentures (CDs). Data: Seventy-three studies reporting on CAD-CAM (milled/3D-printed) CDs were included in this review. Last search was performed on 15/03/2021. Sources: Two investi...
Article
Purpose : To investigate the trueness and marginal fit of computer-aided design–computer-aided manufactured (CAD-CAM) complete-arch implant-supported screw-retained fixed prosthesis (CAISFP) made of polyetheretherketone (PEEK), polyetherketoneketone (PEKK) and titanium (Ti) Material and methods : A typodont model with four implants, their multiuni...
Article
Statement of problem Artificial intelligence applications are increasing in prosthodontics. Still, the current development and performance of artificial intelligence in prosthodontic applications has not yet been systematically documented and analyzed. Purpose The purpose of this systematic review was to assess the performance of the artificial in...
Article
This study evaluated the tensile strength of three aesthetic abutment materials at two different angulations (0 and 15°) to Ti-base and monolithic zirconia crowns. Prefabricated polyvinylidene difluoride (Medentika Implant) abutments were obtained and zirconia (Kingch) and polyetheretherketone (Ceramill) copings were manufactured using a computer-a...
Article
Statement of problem. Selective laser melting (SLM) additive manufacturing (AM) technologies provide an alternative to conventional casting and milling procedures in fabricating metal- ceramic dental prostheses. However, the quality of porcelain bond strength to the SLM AM cobalt-chromium (Co-Cr) metal framework of a dental restoration is unclear....
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The aim of this study was to evaluate four test methods on the adhesion of resin composite to resin composite, and resin composite to glass ceramic. Resin composite specimens (N = 180, Quadrant Universal LC) were obtained and distributed randomly to test the adhesion of resin composite material and to ceramic materials (IPS e.max CAD) using one of...
Article
Objectives: Candida adherence to the denture base is an important cause of denture stomatitis in elderly and handicapped patients where effective patient- and physician-based disinfection methods are required. The purpose of this study was to investigate the in vivo effectiveness of chemical and physicochemical methods and their combinations again...
Article
Purpose: To measure the durability of the color, change in surface roughness and gloss of stained monolithic ceramic materials subjected to artificial tooth brush abrasion. Materials and methods: Standardized specimens were manufactured from pressable lithium-disilicate glass ceramic (PC; IPS e.max Press), machinable lithium-disilicate glass cerami...
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Objectives This study evaluated the effect of restoration occlusal design on the maximum fracture load and stress distribution of a feldspathic ceramic crown. Materials and Methods Twenty dentin analogues were used to simulate a full-crown preparation. Next, 20 feldspathic crowns were milled according to the occlusal design parameter available in...
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Background Wear and quality assessment of translucent monolithic zirconia and CAD-on® restorations were performed. Methods Forty 3-unit posterior FDP in 18 patients (age:18-50yrs) were made from translucent monolithic zirconia (tm) (Zenostar T) and zirconia-frameworked, lithium disilicate layered (c) (CAD-on), materials in a split-mouth design. Re...
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Statement of problem Photogrammetry technology has been used for the digitalization of multiple dental implants, but its trueness and precision remain uncertain. Purpose The purpose of this in vitro investigation was to compare the accuracy (trueness and precision) of multisite implant recordings between the conventional method and a photogrammetr...
Article
Aim: To compare the microleakage of Cention N, a subgroup of composite resins with a resin-modified glass ionomer (RMGI) and a composite resin. Methods: Class V cavities were prepared on the buccal and lingual surfaces of 46 extracted human molars. The teeth were randomly assigned to four groups. Group A: Tetric N-Bond etch-and-rinse adhesive and T...
Article
This study analyzed the fit accuracy of the removable partial denture (RPD) metal frameworks produced using digital and conventional manufacturing technologies. Mandibular RPD metal frameworks (N=15, n=3 per group) were fabricated on a representative clinical case. RPDs were fabricated using one of the following manufacturing procedures: a) convent...
Article
This systematic review and meta-analysis aimed to evaluate the effect of Er:YAG laser etching on shear bond strength (SBS) of brackets bonded to the enamel and compare to the phosphoric acid (control). Electronic databases (PubMed, Scopus, and Web of Science) and a manual search were conducted up to January 2021. In vitro studies comparing Er:YAG l...
Article
Objective To determine whether bond strength to eroded dentin is similar to values found for sound dentin, before and after additional treatments. Materials and methods MeSH terms and keywords relative to the topics ‘adhesion to dentin’ and ‘eroded dentin’ were searched in the Pubmed and the Scopus databases. In vitro studies that compared the bon...
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This study aimed to evaluate two hydrogen peroxide (HP)-based at-home bleaching systems in order to analyze whether nano-hydroxyapatite (nHA) addition may represent a reliable and safe solution for tooth whitening without altering dental microstructure and hardness. Human third molars (N = 15) were treated with two bleaching agents, one containing...
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Objective The main aim of this study was to conduct an integrative review on the influence of the zirconia veneer thickness on the degree of conversion of resin-matrix cements. Materials and method An electronic search was performed on PubMed using a combination of the following search items: zirconia, thickness, veneer, degree of conversion, resin...
Article
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Currently, minimally invasive restorations could be made in dentistry applying adhesive materials and adhesion principles to the dental structures. Following this philosophy, endodontic interventions have been avoided largely, preserving hard tissues, and maintaining dental vitality. Advances in biologically favorable bioactive materials enabled cl...
Article
In the RLT (Rapid Layer Technology), veneering ceramic and framework are fabricated by computer-aided design/computer-aided manufacturing (CAD/CAM) and then cemented to obtain the restoration. This study aimed to evaluate the effect of the thickness of veneering ceramic manufactured by the RLT technique on the fracture resistance (FR) of bilayer cr...
Article
Sealing the occlusal pits and fissures of molars and premolars is considered an effective therapy for the prevention of dental caries. Such sealants have limited wear resistance, resulting in surface damage and sealant volume loss. The purpose of this study is to perform an integrative review of the literature on wear pathways of current tooth occl...
Article
Statement of problem: Monolithic zirconia restorations have been evaluated with in vitro studies, but limited clinical evidence of their longevity and reliability is available. Purpose: The purpose of this clinical study was to evaluate the clinical performance of posterior multiunit glazed monolithic zirconia fixed dental prostheses. Material...
Article
Aim: This clinical technique report aimed to describe a composite resin repair technique performed in an implant-supported prosthesis. Background: Veneering ceramic fracture or chipping is one of the most frequent clinical failures in dentistry. Therefore, the use of less time- and cost-consuming ceramic repair techniques is helpful in clinical...
Article
Objective: Despite the increased popularity of endocrowns, there is no clear consensus considering their effectiveness to restore severely-destructed endodontically treated premolars. This study aimed to assess the biomechanical behavior of endodontically treated maxillary first premolars restored with a novel endocrown system compared to the conv...