Muthuchamy Murugavel

Institute for Chemical Reaction Design and Discovery · Structural Chemistry (Prof. Yasuhide INOKUMA)

Visual observations are frequently used for the preliminary evaluation of the chemical contents of mixtures, but their accuracy largely depends on the observer's experience and intuition, which are difficult to share. Here, we report component ratio prediction using image-based machine learning (ML), which is applicable to the analysis of various s...

Visual observations are frequently used as a preliminary evaluation of the chemical contents of mixtures, but their accuracy largely depends on the observer’s experience and intuition, which are difficult to share. Here, we report component ratio pre-diction using image-based machine learning (ML), which is applicable to analysis of various solid m...

The anion bound and palladium complexes of 2,6-di-m-phenylpyridine embedded isosmaragdyrin [1.1.1.0.0] with N3C2 core are successfully synthesized. The anion bound complex is achieved by the addition of trifluoroacetic acid (TFA)...

Cyclic oligoketones composed of 3,3-dimethylpentane-2,4-diones showed crown ether-like alkali metal ion binding behavoir with association constants up to 1.7 x 10 ⁴ M –1 in chloroform/acetonitrile (v/v, 9/1). The binding properties have...

The N‐confused pyritriphyrin(3.3.1) was synthesized by switching the bonding mode of subpyriporphyrin with inclusion of two o ‐phenylene rings in the macrocyclic core and prevails nonaromatic character due to the local aromatic characteristic of the embedded 3,5‐diphenylpyridyl unit. The simplest contracted derivative of N‐confused pyricalixphyrin...

The three-dimensional (3-D) cryptand-like normal and doubly-N-confused calixbenzophyrins embedded with phenyl rings in the macrocyclic skeleton are successfully synthesized from single starting materials. These structural isomers are characterized by spectral studies and unambiguously confirmed by crystal analyses.

Metal ion adsorbents are indispensable materials for the recovery of noble metal ions in a sustainable society. Herein, we report that poly(isopyrazole‐3,5‐diyl‐ trans ‐vinylene) ( 1 ) effectively adsorbed group 10 metal ions from solution in acetonitrile. Owing to its fully π‐conjugated and rigid structure, polyimine 1 was virtually insoluble in c...

Isosmaragdyrin with N3C2 core is successfully achieved by introducing a 2,6-Di-m-phenylpyridine unit. The core is utilized to stabilize Rh(I) ion with N-Rh(I)-N bonding mode and Pt(II) ion with (N^C)N fashion...

A new rectangular-shaped carbadecaphyrin was successfully synthesized by introducing a terphenylene unit (m-m-m) in the macrocyclic core. The terphenylene moiety offers an open framework with multiple binding pockets to stabilize two Rh(I) ions in the core. The photophysical and structural studies reveal the non-aromatic character of the ligand and...

Homotrimetallic manganese(III) corrole-porphyrin-corrole triad has been synthesized and structurally characterized. Corrole and porphyrin rings in free base corrole-porphyrin-corrole triad are found to be roughly perpendicular to each other having a dihedral angle of 83° in the solid state. Dihedral angle of roughly 67° was found between Mn(III)-co...

meso-Tetraphenylbenzene (TPB) substituted porphyrin hybrids have been designed and synthesized. The meso-TPB-porphyrin hybrids exhibit two discrete atropisomers due to restricted rotation around \(\hbox {C}_{meso}\)–\(\hbox {C}_{\text {TPB}}\) bond. Both the atropisomers could be structurally characterized. The photophysical and electrochemical pro...

We report the synthesis and characterization of porphyrin-corrole-porphyrin (Por-Cor-Por) hybrids directly linked at the meso-meso positions for the first time. The stability and solubility of the trimer are carefully balanced by adding electron-withdrawing substituents to the corrole ring and sterically bulky groups on the porphyrins. The new hybr...

An electron deficient Cu(III)-corrole (B) has been identified as a highly selective colorimetric sensor for iodide. A one-electron redox couple between iodide and Cu(III)-corrole serves as the basis for selectivity. The proposed mechanism has been supported by UV-vis and 19F NMR studies and further by unambiguous identification of Cu(II) species th...

A first example of a directly-linked corrole–porphyrin–corrole (Cor– Por–Cor) triad has been targeted and synthesized. The new hybrid has been fully characterized by 1 H NMR, 19 F NMR and 2D NMR spectros-copy. The fluorescence quantum yield of the triad is three times higher than that of meso–meso directly linked porphyrin trimers. All the three ch...

A series of phenoxy linked bisquinoline derivatives were synthesised from the Friedlander annulation of 2-(4-acetylphenoxy)-1-aryl-1-ethanones with 2-aminobenzophenone in good yields using (±)-camphor- 10-sulfonic acid (CSA) as the catalyst. These compounds were screened for their in vitro activity against Mycobacterium tuberculosis H37Rv (MTB) and...