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Muthanna Al-Ezzi

Muthanna Al-Ezzi
Mustansiriyah University-College of Pharmacy · Department of Pharmacology and Toxicology

PhD

About

19
Publications
548
Reads
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16
Citations
Citations since 2017
10 Research Items
16 Citations
201720182019202020212022202301234
201720182019202020212022202301234
201720182019202020212022202301234
201720182019202020212022202301234
Introduction
Skills and Expertise

Publications

Publications (19)
Article
Background: Metabolomics is an international technique used in clinical practice to predict or evaluate diseases by studying the endogenous level of small molecule metabolites. The lipid-lowering effects of atorvastatin (ATO), fenofibrate (FEN), and ATO+FEN in hyperlipidemia induced by high cholesterol diet (HCD) were studied by metabolomics techno...
Article
Full-text available
Background: Acute myocardial infarction (AMI) is an atherosclerotic disorder of myocardial necrosis caused by constriction of blood supply to the heart, leading to myocardial dysfunction and death of the heart cells. Vitronectin (VN) is a regulatory plasma glycoprotein, which adjusts the adhesion processes of platelets, accumulation and coagulation...
Article
Herbs have been utilized for all time as the significant sours of medication. Medical plants are significant by optional metabolites, for example; Silybum marianum, is a remedial herb with a thousand years history of utilization. It is a blend of flavonoids, called silybin, which isn't just the major silymarin component but at the same time is the...
Article
Full-text available
Doxorubicin is a secondary metabolite of Streptomyces peucetius and is one of the anthracyclines families, greatly effective anticancer drugs that used to treat many pediatric and adult cancers, e.g. solid tumors, lymphomas, leukemia and breast cancer. Doxorubicin has severe toxicities, but the cardiotoxicity being the most important. Metformin has...
Article
Cyclooxygenases enzymes (COX) are related with ovulation, apoptosis and menstrual disorder. Several studies demonstrate that COX 1 is one of the major sources of prostaglandin but COX 2 is more important in the late reproductive age women. Prostaglandin is bioactive compound excreted from Arachidonic acid by Cox 1 and Cox 2, play role in the fertil...
Article
Back ground: Doxorubicin is a very effective anticancer therapy of the anthracycline's family used in many pediatric and adult cancers. However, due to severe cardiotoxicity adverse effect, the uses of doxorubicin are limited. Metformin reducing basal and postprandial glucose levels. Metformin has a good treatment efficacy and safety profile in tre...
Article
Doxorubicin is one of the highly effective anti-neoplastic drugs of the anthracyclines family used to treat many pediatric and adult cancers, However the clinical used of doxorubicin is limited due to severe cardiotoxicity side effect. Metformin reducing basal and postprandial glucose levels. The Metformin antihyperglycemic effect seems to reduce c...
Article
Metformin, a biguanide, first line antidiabetic agent, undergoes extensive debate to explain its possible cardioprotective effect. This study represents an attempt to help clarifying this cardioprotective effect. 24rats divided into three diabetic group (8 rats for each) (diabetes induced by Streptozocin 60 mg/kgi.p.). Diabetic groups treated with...
Article
Full-text available
Study was done in the period between (2015-2017) in biology department in college of Education for pure science/Ibn Al-Haitham at Baghdad University and in Pathology department/college of medicine at Al-Nahrain University.The study was retrospectively designed.The clinicopathological parameters were obtained from patients’ admission case sheets and...
Article
This study was conducted to determine the essential oil percentage of three natural gums of three medicinal plant, Commiphora molmol (myrrh), Boswellia serrata (Indian frankincense) and Aloe vera (true aloe) with evaluation of the antihyperledemic activity of the extracts of the three plants in rats. After converting all resins to powder the essent...
Article
Full-text available
Objective: The objective of the study was to investigate the effect of dietary flaxseed-derived lignan supplement as anti-hyperlipidemic (fatty liver changes) on rabbit liver. Methods: Rabbits were assigned randomly into three groups (five rabbits for each group): group-1, normal diet (negative control); group-2, 1.6 % cholesterol diet for 30 d (po...
Article
Diabetes mellitus (DM) is a metabolic disorder that can cause microvascular and macrovascular complications which increase the possibility of morbidity and mortality. Diabetic cardiomyopathy (DCM) characterized by functional and structural dysregulation of the heart in DM in which hyperglycemia is the main factor involved in DCM pathogenesis. Diabe...
Article
Patients with cardiovascular diseases or erectile dysfunction initially present to primary care physicians, who have an opportunity to intervene early andfavorably affect the clinical course of either condition. Recognition and aggressive treatment of cardiovascular disease risk factors has a major role in management of cardiovascular disease and e...
Article
The present study was conducted to prepare Rose Bengal antigen by using Rose Bengal stain 1% and brilliant green 0.5%. These antigens were prepared usingdifferent concentrations (4%, 5%, 6%, 7%, 8%, 9% and 10%) and different buffer diluents with different pH (3.0, 3.5, 3.65, 4, 4.5, 5.0) to study the effect of differentantigen concentrations and pH...
Article
The current study handled the preparation of a tube agglutination test antigen from a record culture Brucella Abortus S99 according to the European method and at different concentrations (1%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5% and 5%), by adding additional microbial cells, these concentrations were compensated by different temperatures (60, 70, 80, 95 an...

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