Mutangana Dieudonne- Doctor of Philosophy
- Head of Department at University of Rwanda
Mutangana Dieudonne
- Doctor of Philosophy
- Head of Department at University of Rwanda
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34
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Publications
Publications (34)
Although the central role of biology in nation’s scientific and technological advancement is unquestionable, the academic achievement of students in the subject has been subpar. To cope with this situation, researchers in science education have continued to look for a successful way to teach and learn biology concepts. The present study, therefore,...
Atherosclerosis poses significant health risks, driving cardiovascular issues like heart attacks and strokes. Shortage of appropriate pathophysiological models and a suitable algorithm for the discovery of drugs and para-pharmaceuticals with direct anti-atherosclerotic action are major barriers to the effective pathogenetic medication for atheroscl...
p style="text-align: justify;">The study investigated the attitudes of Biology teachers towards the Biology Competence-Based Curriculum (BCBC) and their instructional practices at the lower secondary school level in Nyamagabe district, Rwanda. A descriptive survey design was adopted. Also, a purposive sampling technique was used to select 26 (16 ma...
The effects of Concept Mapping (CM) and Cooperative Mastery Learning (CML) strategies on students' attitudes towards biology were investigated in this study to instill a positive attitude in students toward biology. The study adopted a quasi-experimental, non-equivalent control group design with pre-and post-tests. A total of 449 senior secondary s...
span lang="EN-US">Students’ performance in biology in Rwanda National Examinations has been reported to be unsatisfactory. This demands teachers to shift to methods that enable students to acquire meaningful learning. In an attempt to cope with this situation, the effects of concept mapping (CM) and cooperative mastery learning (CML) on the cogniti...
The emergence of the SARS-CoV-2 Delta variant of concern (lineage B.1.617.2) in late 2020 resulted in a new wave of infections in many countries across the world, where it often became the dominant lineage in a relatively short amount of time. We here report on a novel genomic surveillance effort in Rwanda in the time period from June to September...
Literature confirms that students’ engagement in biology is necessary predictor of their learning outcomes. However, how to do so is less certain. Therefore, this study investigated whether students taught biology using Cooperative Mastery Learning (CML) had different perceptions of learning environment and engagement when compared to those taught...
Campylobacter jejuni is one of the major aetiologies of diarrhoea. Understanding the processes and virulence factors contributing to C. jejuni fitness is a cornerstone for developing mitigation strategies. Two-component signal transduction systems, known as two-component systems (TCSs), along with single regulators with no obvious cognate histidine...
Students' low performance in biology perturbs many teachers and other stakeholders. This has sparked research into learning strategies that might be utilized to improve students’ performance in the subject. This study investigated the effects of Concept Mapping (CM) and Cooperative Mastery Learning (CML) on students' achievement in photosynthesis....
p style="text-align: justify;">The performance in biology at the secondary level has not been as good as expected. This has been a matter of concern. Thus, there has been a continuous focus on exploring newer innovative learner-centered and friendly instructional strategies to enhance understanding and retention in biology. This study, therefore, d...
A growing number of Campylobacter species other than C. jejuni and C. coli have been considered as emerging human and animal pathogens but their contribution to human gastroenteritis is poorly documented. This study aimed at detecting Campylobacter species from human and cattle faecal samples in Kilosa District, Tanzania using molecular techniques...
Inland fisheries are important socioeconomic resources for rural communities in Africa. In Rwanda, about two million people directly depend on capture fisheries from Lake Kivu. Sustainable fisheries management requires monitoring of population dynamics that help devise effective intervention strategies. However, the relevant data such as length-len...
Thermophilic Campylobacter species of poultry origin have been associated with up to 80% of human campylobacteriosis cases. Layer chickens have received less attention as possible reservoirs of Campylobacter species. Initially, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of two archived Campylobacter isol...
Mouse Zinc finger domain-containing protein19 (ZMYND19) is a zinc-finger protein questioned after recently published data reported its C-terminal domain of 49 residues to be associated with cancer, obesity and cardiovascular diseases. The potent drugs are suggested to come from its interactions with ligands understanding. However, the diseases are...
Thermophilic Campylobacter species cause human gastroenteritis globally. This study assessed the antimicrobial resistance (AMR) profiles, virulence genes, and genetic diversity of thermophilic Campylobacter species isolated from a layer poultry farm in Korea. In total, 153 chicken faeces were collected from two layer farms. Campylobacter isolation...
Heavy metals are among the pollutants that threaten living organisms including human beings. Heavy metals in water are of great concern due to their toxicity and ability to bio-accumulate in aquatic organisms. There is a need to regularly monitor their concentration in an aquatic medium. The present study was conducted to evaluate the level of heav...
Thermophilic Campylobacter species are among the major etiologies of bacterial enteritis globally. This study aimed at assessing the antimicrobial resistance (AMR) profiles, virulence genes, and genetic diversity of thermophilic Campylobacter species isolated from a layer poultry farm in South Korea. One hundred fifty-three chicken feces were colle...
Campylobacter species have developed resistance to existing antibiotics. The development of alternative therapies is, therefore, a necessity. This study evaluates the susceptibility of Campylobacter strains to selected natural products (NPs) and frontline antibiotics. Two C. jejuni strains (ATCC® 33560TM and MT947450) and two C. coli strains (ATCC®...
The impact of students' self-efficacy beliefs about their academic performance and motivation in all stages of their academic endeavour has been a major concern to many researchers. It contributes greatly to the overall total development and success of the student even at their progression to the next level in their educational development. The pur...
Background: A growing number of Campylobacter species other than C. jejuni and C. coli have been considered as emerging human and animal pathogens. However, the contribution of these species to human gastroenteritis is poorly documented. This study aimed at detecting Campylobacter species from human and cattle faecal samples in Kilosa district, Tan...
Melanin concentrating hormone receptor 1 is a G-protein coupled protein receptor expressed in the lateral hypothalamus and zona incerta, part of the nervous system that regulates feeding behavior and energy homeostasis. It is involved in the stimulation of appetite, this was seen when synthetic MCHR1 or MCH was administered to mice and it resulted...
Thermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. A review of publ...
Lyme disease is caused by the spirochete Borrelia burgdorferi which enters into the skin by feeding ticks, mainly Ixodes species. Spread of the pathogen into the blood results in various symptoms. Because some individuals do not show any symptom following the infection, it is very difficult to diagnose the infection caused by this spirochete. When...
Melanocortin system is composed of four peptide hormones known as α, β, γ and adrenocorticotropic hormone (ACTH), derived from post-translational cleavage of a polypeptide precursor ‘proopiomelanocortin (POMC)’. Among these hormones; β-melanotropin stimulating hormone (β-MSH), an 18 amino acid residue peptide fragment is an important hormone as it...
Heat-shock proteins (Hsps) are molecular chaperones regulating protein folding so as to ensure correct conformation, translocation and to avoid protein aggregation. Despite Hsps playing a cytoprotective role and protect the cells from adverse stressful stimuli, some of them such as Hsp90 are involved in the maturation and stabilization of a variety...
Abstract Melanocortin system is composed of four peptide hormones namely α-, β-, -γ and adrenocorticotropic hormone (ACTH), derived from post-translational cleavage of a polypeptide precursor 'proopiomelanocortin (POMC)'. Among these hormones, ACTH, a 38 amino acid residue peptide fragment is an important hormone as it is involved in steroid secret...
![Fig. 4-(i) Optimized structure of hydrogen phosphate [HPO 4 ] computed...](profile/Mutangana-Dieudonne/publication/260612411/figure/fig3/AS:669568708136975@1536649028451/i-Optimized-structure-of-hydrogen-phosphate-HPO-4-computed-by-B3LYP-6-31G-level-of_Q320.jpg)
![Fig. 4—(i) Optimized structure of hydrogen phosphate [HPO 4 ] computed...](profile/Mutangana-Dieudonne/publication/261136888/figure/fig3/AS:392516307308544@1470594588365/i-Optimized-structure-of-hydrogen-phosphate-HPO-4-computed-by-B3LYP-6-31G-level-of_Q320.jpg)
Rice cultivation under aerobic condition not only saves water but also opens up a splendid scope for effective application of beneficial root symbionts in rice crop unlike conventional puddled rice cultivation where water logged condition acts as constraint for easy proliferation of various beneficial soil microorganisms like arbuscular mycorrhizal...
Due to resistance developed by various agricultural pests towards Bacillus thuringiensis (BT) toxins, there is a necessity of
developing alternative biopesticide. The TcaA toxin produced by Photorhabdus luminescens is a high molecular weight
insecticidal toxin having toxicity against wide range of agricultural pests. Phylogenetic tree constructed...
Genetic engineering of Cry proteins from Bacillus thuringiensis (BT) has resulted in the synthesis of various novel toxin
proteins which exhibits increased insecticidal activity and highly specificity towards different insect pests. The present study
focused on computational studies on PirB sequence from Photorhabdus luminescens. The consensus tre...
Sequential dark-photo fermentations (SDPF) was used for hydrogen production from bagasse, an acetaldehyde dehydrogenase (adhE) gene inactivated Klebsiella oxytoca HP1 (DeltaadhE HP1) mutant was used to reduce the alcohol content in dark fermentation (DF) broths and to further enhance the hydrogen yield during the photo fermentation (PF) stage. Comp...
Questions
Questions (2)
The attached table shows various free energies of one protein complexed with various ligands, I have subjected all 4 complex structures to MD simulation, output presented in this table are computed using MM-PB/GBSA aproach. I have to select one complex having better interaction based on binding free energy (PBTOT or GBTOT). Would you please mind helping me out?
Is there any correlation between the value of Delta G and the stability of the protein complex?
