
Mustafa SevindikOsmaniye Korkut Ata University · Department of Biology
Mustafa Sevindik
Assoc. Prof. Dr.
Osmaniye Korkut Ata University
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Introduction
Skills and Expertise
Publications
Publications (265)
Plants are vital natural resources that are used in a wide range of applications. Throughout history, these tools have proven to be valuable assets for individuals. We conducted a study to assess the biological activity of the aerial portions of Thalictrum minus L. In this particular situation, the plant's ethanol and methanol extracts were obtaine...
Plants are organic substances extensively utilized in conventional medicinal procedures. We conducted a comprehensive review of the literature to assemble information on the biological activities, areas of use, total phenolic and flavonoid concentrations, as well as the chemical and phenolic compositions of Lycium barbarum L. The literature investi...
In this work, artificial neural network coupled with multi-objective genetic algorithm (ANN-NSGA-II) has been used to develop a model and optimize the conditions for the extracting of the Mentha longifolia (L.) L. plant. Input parameters were extraction temperature (40–70 °C), extraction time (4–10 h), and extract concentration (0.25–2 mg/mL) while...
Phenolic molecules are secondary metabolites that facilitate several biological processes. Secondary metabolites are non-nutritive substances that hold significant medicinal value. Our study combined the biological activities, general features, daily usage conditions, and biosynthesis of luteolin as reported in the literature. The literature review...
Plants are one of the constant elements of the ecosystem. These features pave the way for its use formany purposes. In our study, the biological activities of Viola odorata reported in the literature werecompiled. V. odorata (Violaceae) is known by names such as ''wood violet, sweet violet, English violet,common violet''. It is known as a garden pl...
Plants have been used for many different purposes from past to present. In this study, the biological
activities of Apium graveolens reported in the literature were compiled. It is also known as wild celery.
It is distributed in many different regions geographically. It is a biennial or monocarpic perennial plant.
In literature studies, it was obse...
Plants display several biological activities as a result of the production of various chemicals inside their
metabolic processes. In recent times, the growing prevalence of alternative medicine uses has elevated the
significance of plants. The present work aimed to assess the biological activities, phenolic and chemical
compositions, applicabili...
Plants are used in many different areas such as cosmetics, textile dyes and pharmaceutical industry. In
this study, the biological activities of Salacca zalacca reported in the literature were compiled. Salacca
zalacca is in the Arecaceae family. It is known as snake fruit. Its geographical homeland is Indonesia.
Snake fruit is a palm tree speci...
Throughout history, people have been intertwined with plants. This association has paved the way for
people to use plants for different purposes. In this study, the biological activities of Litchi chinensis
reported in the literature were compiled. L. chinensis is in the (Sapindaceae) family and is known as
lychee. As a result of the literature...
In this study, the phenolic and chemical contents, physiological properties and biological activities of Origanum laevigatum Boiss (O. laevigatum) were determined. The chemical study revealed that the plant included vanillic, caffeic and hydroxybenzoic acids as well as resveratrol and phloridzin. The greatest concentration , 13.45%, was identified...
There is a serious increase in the number of viral diseases today. Monkeypox virus (M-Pox/MPXV) is defined as a viral infection caused by a virus called Orthopoxvirus in the Poxviridae family. It is frequently found in the tropical rainforests of West and Central Africa. However, it has spread to other countries over time. In this study, the Monkey...
Effect of the composition of a biologically active dietary supplement with macrofungi mycelia on its antioxidant activity. Regulatory Mechanisms in Biosystems, 15(4), 932-938. The global demand for macrofungi is driven by their rich content of biologically active substances and trends such as the need for natural medicines, the growing popularity o...
ZET Geleneksel tıp kapsamında birçok bitki türü doğrudan doğadan temin edilerek kullanılmaktadır. Bitkiler insanlar tarafından hastalıklarla mücadele gibi farklı amaçlarla kullanılmaktadır. Çalışmamızda Hypericum perforatum'un literatürde bildirilen biyolojik aktiviteleri derlenmiştir. H. perforatum sarı kantaron olarak bilinmektedir. Dünyanın birç...
Plants are used for different purposes such as aroma and flavor, cosmetics, clothing, weapons, fuel, and shelter. In our study, the biological activities of Sinapis alba reported in the literature were compiled. S. alba (Brassicaceae) is known as white mustard. Although its geographical homeland is the Mediterranean region, it is widespread in many...
The increasing world population and the negative effects of climate change are causing crises in the areas of food and health. Researchers and large companies are working to solve these problems and sometimes they are even competing. This competition can sometimes lead to some risks being ignored in the studies and sometimes to unfair actions such...
66 bands were obtained and the polymorphism rate was 96.96%. In the ISSR-PCR analysis, 119 bands were obtained and the polymorphism rate was 95.79%. In the UPGMA (Unweighted Pair Group Method with Arithmatic Mean) dendrogram based on RAPD-PCR, B. angustifolia and B. glabrescens were found to be a sister group, and B. kiyakii and B. cappadocica were...
Optimizing extraction conditions can help maximize the efficiency and yield of the extraction process while minimizing negative impacts on the environment and human health. For the purpose of the current study, an artificial neural network (ANN) combined with a genetic algorithm (GA) was utilized for that the extraction conditions of Hypericum spec...
Since ancient times, humans have been able to employ several natural materials in the treatment of illness and injury thanks to the practice of complementary medicine. Many plants, animals, and fungi have proven effective in the treatment of sickness in humans. Among these natural resources, plants play a significant role. In our study, studies in...
Plants are natural resources responsible for different biological activities. Determining the biological activities of plants is very important. In our study, some biological activities and total phenolic and flavonoid contents of Loranthus europaeus Jacq. were determined. In this context, ethanol and methanol extracts of the plant were obtained us...
Plants, with their natural and nutritional properties, are also important sources of medicine. The study aimed to determine total phenolic, total flavonoid, total oxidant, total antioxidant, antiproliferative and antimicrobial activities of parts of the celery (Apium graveolens L.) plant. Samples of celery were gathered in Turkey and Iraq. Celery p...
Today, many plant species come to the fore with their medicinal potential. Plants are medically important natural resources. In our study, the biological activities of Equisetum ramosissimum were determined. Additionally, total phenolic and flavonoid contents were measured. The aboveground parts of the plant were extracted with ethanol and methanol...
Cornelian cherry is an important plant called ‘Super plant’, which is consumed using different parts around the world. Especially the fruit parts of the plant are consumed as food. In addition, parts such as flowers, seeds and fruits are rich in essential oils. It is used in traditional medicine to treat diseases such as respiratory infections and...
Plants containing phenolic secondary metabolites such as tannins and flavonoids are of great interest due to their antioxidant and antimicrobial effects on health. Many species belonging to the Astragalus genus possess promising bioactive phyto-compounds and are used in folk medicine worldwide. In this study, extracts were obtained using two differ...
Plants are natural products used in the prevention and treatment of many diseases. In this study, antioxidant, antimicrobial, anticholinesterase activities and total phenolic and flavonoid contents of Tagetes patula L. samples collected from Iraq were determined. In this context, the aerial parts of the plant were extracted with ethanol in a soxhle...
Phenolic compounds are important compounds responsible for many therapeutic, pharmacological, and biological activities. They are compounds that do not have nutritional properties but are very important from a medical point of view. In this review, general properties, derivatives and biosynthesis, pharmacological and therapeutic effects, biological...
Plants contain many bioactive compounds. These bioactive compounds are responsible for many different biological activities. The use of plants in complementary medicine is becoming increasingly common. The bioactive compounds in it highlight the use of plants in complementary medicine as a natural product. Many studies have shown that plants have m...
Mushrooms are one of the indispensable elements of human diets. Edible mushrooms stand out with their aroma and nutritional properties. In this study, some biological activities of the wild edible mushroom Hericium erinaceus were determined. In this context, firstly, the most suitable extraction conditions of the fungus in terms of biological activ...
Aims: This study aims to determine the myxobiota of the Iskenderun Bay and its environment. Material and methods: This study was carried out on samples collected from 9 different stations in İskenderun Bay district in 2019-2022. Myxomycetes samples was collected from leaf, tree bark, decayed and non-rotting plant materials. Our aim is to detect bot...
Mushrooms are natural products with many biological activities. In this study, antioxidant, antimicrobial, anticholinesterase activities and element levels of Lycoperdon pratense Pers. were determined. In this context, the mushroom was extracted with ethanol in a soxhlet device. Antioxidant potential was determined using Rel assay kits. Antimicrobi...
Mushrooms are cosmopolitan living groups. They stand out with their nutritional and aromatic properties. Apart from these features, they are also medically important natural materials. In this study, the biological activities of Trametes versicolor reported in the literature were compiled. As a result of the research, it has been determined that th...
Plants have been widely used by humans since ancient times. They serve different purposes, especially shelter, heating, nutrition, war, equipment and medicine. Nowadays, they are widely used especially in the fight against diseases. In this context, in this study, the biological activities and health effects of Salvadora persica L. reported in the...
Mushrooms are invariable components of natural ecosystems. Today, they are used by humans for different
purposes. In this study, some biological activities of wild mushroom Suillus bellinii (Inzenga) Kuntze were
determined. In this regard, ethanol and methanol extracts of the mushroom were obtained using Soxhlet
apparatus. Anticholinesterase activi...
Pleurotus ostreatus strain IBK551 (HK-35, Sylvan, USA), a promising object for use in food and other industries, has been investigated for mycelium growth on varies solid and liquid media and its acquisition of various biological activities: antagonistic, antibacterial, antiradical scavenging, sorption capacity, and total phenolic content. Almost i...
Plants are unique resources utilised by various communities within natural products. The use of plants within the scope of traditional medicine has significant contributions in the treatment of diseases. The investigation of the potential therapeutic effects of plants within this scope is important in terms of their utilisation as natural resources...
Biological Activities of ethanol extracts of Hericium erinaceus obtained as a result of optimization analysis
In alternative and complementary medicine, plant-based remedies have prominent roles. Here, we analysed the wild mint, Mentha longifolia (L.) L. collected from Mangesh/Duhok (Iraq) for its phenolic and essential oil content, total antioxidant status (TAS) and total oxidant status (TOS), DPPH free radical scavenging activity, antibacterial, antiprol...
Background
The production of Pleurotus ostreatus mycelium as a promising object for use in food and other industries is hampered by a lack of information about the strain-specifcity of this fungus mycelium growth and its acquisition of various biological activities. Therefore, this research aimed to investigate mycelial growth of diferent P. ostre...
Mushrooms have served a variety of functions throughout human history. In addition to being useful as a food, it also has powerful therapeutic benefits. The nutritional value of the edible fungus Clitocybe odora (Bull.) P. Kumm was evaluated by measuring its total phenolic, total antioxidant, total oxidant, and total flavonoid contents. In this cas...
Plants of the Hypericum L. genus are widely distributed with several identified speciesall over the world. In addition to their nutritional properties, plants of the Hypericum L.genus are also noteworthy for their pharmacological properties. These plants have long beena part of traditional medicine in many nations. The present work presents a brief...
In this study, antioxidant (TAS), oxidant (TOS) and antimicrobial activities of samples collected from Osmaniye province, which is located in the Eastern Mediterranean Region of Turkey and where Arum dioscoridis Sm. consumption is common, were determined. Water extracts of leaf parts of plant samples were obtained in a soxhlet device. TAS and TOS s...
Plants have been used by many communities for different purposes such as food, shelter, medicine. The present study aimed to determine phenolic content and biological potential of Glaucium alakirensis Aykurt, K. Yıldız & A. Özçandır, which is endemic to Antalya (Turkey). Phenolic composition of the plant was analyzed with HPLC device, while antirad...
Fomitopsis betulina is a widespread macromycete with valuable medicinal potential. This study screened 22 different F. betulina strains for mycelial growth on various media and exopolysaccharide production. Strain-specific features of F. betulina growth and exopolysaccharide production on different media were observed. Variations in the growth rate...
In our study, the biological activities of the wild edible mushroom Cantharellus cibarius were determined. First of all, 64 different experiments were performed in the Soxhlet device at 40-70°C extraction temperatures, 4, 6, 8, and 10 h of extraction time and 0.25, 0.50, 1, and 2 mg/mL extract concentrations, and total antioxidant (TAS) and total o...
In this study, the biological activities of Lactarius deliciosus were determined. Experimental studies were carried out using a soxhlet device, in the range of 40-70°C extraction temperature, 3-9 h extraction time and 0.5-2 mg/ ml extraction conditions. A total of 64 different extracts were obtained using four different values of each variable and...
Mushrooms have been used for both culinary and medicinal reasons for a very long time. Mushrooms are useful as both a food and a medication due to their high nutritional, protein, vitamin, and phenolic content. The current research aims to determine the antioxidant activity and phenolic content of Hebeloma sinapizans. Multiple epidemiological resea...
Plants are responsible for many different biological activities. In our study, antioxidant, antimicrobial and anticholinesterase activities of Dittrichia graveolens (L.) Greuter were determined. In addition, the total phenolic and flavonoid contents of the plant were measured. The aerial parts of the plant were extracted with ethanol. Antioxidant a...
Macrolepiota procera is a common parasol mushroom of classified under the family “Agaricaceae”. Recent reports
indicate dynamic properties such as anti-inflammatory, antioxidant, immunomodulatory compounds,
antiangiogenic, topoisomerases, and apoptosis inducers. In view of encompassing such versatile combinations, the
innate properties of this mush...
Plants are natural products responsible for many biological activities. It is quite common to use plants that attract attention with their nutritive properties within the scope of complementary medicine. Matricaria species, which have naturally distributed, are among the plants used in traditional medicine. Revealing the biological activities of pl...
Pleurotus ostreatus mycelium is widely used as a base for a variety of food and other products. This study focuses on P. ostreatus strains, increasing the production of their mycelium, studying some valuable biological properties in order to select the best strain. Using of nutrient media based on combination of natural waste (amaranth flour cake a...
Mushrooms, regarded as a significant component of the ecosystem, are utilised by individuals for various purposes. The present study aimed to investigate the biological activities of Agrocybe praecox (Pers.) Fayod, commonly referred to as the Spring Fieldcap mushroom. The ethanol extract of the mushroom was obtained with the Soxhlet apparatus. Subs...
Plants, like many natural products, are used in the fight against diseases within the scope
of traditional medicine. In this study, the biological activities of Juglans regia L. reported in
the literature were compiled. J. regia plant is known as Persian walnut, English walnut,
Carpathian walnut, Madeira walnut, common walnut. It is in the Juglanda...
Plants always coexist with human beings due to the ecosystem in which they exist. This
finding method has always been preferred in many different situations. In this study, the
biological activities of Corylus avellana reported in the literature were compiled. C. avellana
is known as "Hazelnut". It is in the Betulaceae family. The hazelnut plant is...
Plants are important natural products responsible for many biological activities. In this
study, the biological activities of Brassica oleracea var. italica reported in the literature were
compiled. B. oleracea var. italica is known as "Broccoli". It is in the Brassicaceae family.
Broccoli is a plant with large flowered heads, stems and small leave...
Plants are very rich in active ingredients. This richness of active ingredients is an
indication that it is very important in terms of biological activity. In this study, the biological
activities of Ficus carica reported in the literature were compiled. Ficus carica is known as
"Fig". It is in the Moraceae family. The fig plant is a small deciduou...
Throughout history, people have constantly sought a cure for emerging diseases. Plants,
as well as many natural products, have been preferred for disease treatments. In this study, the
biological activities of Laurus nobilis L. reported in the literature were compiled. L. nobilis is
known as bay laurel, sweet bay, true laurel, Grecian laurel or sim...
Plants have been used for many different purposes such as cosmetics, medicine, food,
clothing and shelter. Recently, the use of plants has been mostly in the field of health. The
biological activities of Vaccinium myrtillus L. reported in the literature have been compiled. V.
myrtillus plant is known as European blueberry, bilberry, blaeberry, wimb...
In this study, the utilisation areas, general characteristics, biological activities, mineral and nutrient contents, and chemical compositions of Papaver species were compiled based on literature data. The research findings indicate that Papaver species are consumed either directly or in conjunction with other food products. Furthermore, it has bee...
Today, many different methods are applied for the correct use of foods and to prevent their deterioration. Ensuring healthy conditions for people in food consumption and consumption of healthy foods is very important for human welfare. In this study, food spoilage, the factors that cause food spoilage, its effects on a global basis, food transport...
Objective: Plants are preferred for biological effect. It is a natural resource used in the field of alternative medicine due to its biological effect. In our study, the total oxidant status (TOS) and oxidative stress index (OSI) and total antioxidant status (TAS) of Viola odorata L. species were detected. In addition, antimicrobial and antiprolife...
In this review, the general properties, derivatives and biosynthesis, pharmacological and therapeutic effects, and biological activities of quercetin were examined to shed light on future studies. The literature search has revealed that the effects of quercetin, which is formed from different substrates, also vary. It has been observed that quercet...
The use of Herbs in nutrition and in medicine has been recognized over the years. Herbal treatment is one of the traditional methods used in the treatment of diseases since early ages. Different plant species in different cultures have been used by trial and error and have been very effective. In this study, information is given about the phytochem...
Agaricus bisporus (J.E. Lange) Imbach; Agaricus campestris L.; Agaricus xanthodermus Genev. - AGARICACEAE
. Yusufjon Gafforov, Mustafa Yamaç, Milena Rašeta, Sylvie Rapior, Mustafa Sevindik, Rui-Lin Zhao , Samantha Chandranath Karunarathna, Manzura Yarasheva et Soumya Ghosh.
Agaricus bisporus (J.E. Lange) Imbach; Agaricus campestris L.; Agaricus xa...
In recent years, there has been an increasing prevalence of cases of autism. There is no general cure for autism; however, there are situational treatments available. In this context, plants may be beneficial in suppressing the conditions that may arise in the disease. This study compiles plant species that have been reported in the literature as p...
Complementary medicine history includes a lot of knowledge based on human history. In this context, different plant species are used in the treatment and prevention of diseases. Plants are important natural productsthat attract attention with their nutritive and non-nutritive compounds. They contain many bioactive compounds that are not particularl...
n many regions, plants are the sole source of natural medicines. The numerous bioactive substances they contain have significant advantages in the prevention and treatment of many ailments. Determining the therapeutic characteristics of plants requires knowledge about their biological activity and essential oil contents. The mineral, nutritional, e...
Plants are a rich natural resource that serve many uses for people. Humans have long relied on plants for a wide range of needs, including sustenance, housing, and health care. People have been looking to nature for medical solutions since ancient times. He accomplished this by experimenting with and repurposing various organic materials. Plants ar...
The nutritional and therapeutic benefits of plants are outstanding. Wild mustard ( Sinapis arvensis L.) collected from different regions was analysed for its phenolic, flavonoid, protein, and biological activity levels. In this case, the plant ethanol extract was obtained using a soxhlet apparatus. Rel assay kits and the DPPH test were used to asse...
Objective: Plants, which are natural materials of great importance to humans, are currently utilised for various purposes. The utilisation of plants with nourishing properties for the treatment of diseases has a long history. Material-Method: In this study, the general characteristics, usage areas, mineral and nutrient contents, biological activiti...
Samples of Sideritis libanotica subsp. kurdica (Bornm.) Hub.-Mor, often known as mountain tea, were gathered in Iraq and analyzed for their antioxidant and oxidant status, DPPH activity, total phenolic and total flavonoid contents. The plant's aerial parts were utilized for this purpose. The levels of antioxidants and free radicals were measured by...
It is known that plants exhibit significant biological activities. Numerous studies have demonstrated the existence of various plants utilised within the scope of complementary medicine. In our study, we compiled the biological activities, chemical contents, utilisation areas, as well as nutritional and mineral contents of Foeniculum vulgare Mill....