Mustafa Doğan

Afyonkarahisar Sağlık Bilimleri Üniversitesi · Ophthalmology

In this cross-sectional study, optical coherence tomography angiography (OCT-A) findings were compared in patients with gout (n = 30) and healthy participants (n = 32). The superficial and deep vessel density variables measured using OCT-A were compared between the groups. The superficial foveal and perifoveal vessel densities of the patient group...

Background: To determine the effects of protein supplement (whey protein powder (PP)) on retinal, choroidal and optic nerve head (ONH) microstructure and microvascular morphology in healthy bodybuilders. Methods: This cross-sectional study included 23 male adults (consumers, 23 right eyes) who had been routinely consuming whey PP for bodybuildin...

Objectives: To evaluate sarcoidosis-induced tear film changes using subjective and objective diagnostic tests, particularly conjunctival impression cytology (IC), and to compare the results with healthy individuals. Materials and methods: This study evaluated clinical data collected between January 2019 and January 2021 from 57 right eyes of 57...

Background: To assess retinochoroidal and optic nerve head microcirculation alterations in cryptogenic organizing pneumonia. Methods: Thirty cryptogenic organizing pneumonia patients in the resolution phase (group 1, 30 right eyes) and 33 healthy subjects (group 2, 33 right eyes) were compared. Patients had 40 mg/day corticosteroids for 8-10 day...

b>Aim: To investigate how frequently over-65-year-old senile macular degeneration (SMD) patients use smartphones and the Internet for disease information, as well as to evaluate website readability and information quality. Material and methods: There were 400 SMD patients who were followed up on at a retina clinic. SMD was defined as the presence o...

Background: To investigate retinal and optic disc (OD) microvascular morphological changes in erythemato-telangiectatic rosacea (ETR) patients using optical coherence tomography angiography (OCTA), and compare the findings to age- and gender-matched healthy individuals METHODS: This study included newly diagnosed 31 ETR patients (31 right eyes, gr...

Background: To examine firefighters (FFs) exposed to high levels of fire smoke and, as a result, to uncover risk factors for dry eye disorder (DED) compared to age-and gender-matched healthy individuals. Methods: In this cross-sectional study, 51 FFs from the Afyonkarahisar Municipality Fire Department were chosen at random (group 1). A control...

Objectives: To assess hearing function in chronic glaucoma patients in comparison to healthy individuals. Materials and methods: This cross-sectional study included 24 primary open-angle glaucoma (POAG) patients (24 ears) and 22 pseudoexfoliative glaucoma (PEG) patients (22 ears) who were followed for at least 5 years in the Afyonkarahisar Healt...

Background: To investigate retinal and optic disc microcirculation using optical coherence tomography angiography (OCTA) in order to predict related outcomes based on the SYNergy Between PCI With TAXUS and Cardiac Surgery (SYNTAX) score (SS) system in coronary artery disease patients. Methods: 104 patients were grouped based on coronary angiogra...

Aim: To compare the impact of competency in intravitreal injection therapy (IVIT)-related simpler versus standard consent forms (CFs). Material and methods: Four hundred patients scheduled for IVIT in a tertiary hospital were enrolled between April 1, 2022 and June 30, 2022. These patients were eligible for the study if they had their first IVIT in...

Background: To evaluate the macular and optic disc vascular changes in vitamin B12 deficiency anemia. Methods: A total of 24 patients with vitamin B12 deficiency anemia and 24 healthy controls were involved in this study. All participants were evaluated for central macular thickness (CMT), peripapillary retina nerve fiber layer (RNFL) thickness,...

Purpose: The purpose of the study was to investigate detailed optic disc, choroid, and retinal microvascular morphological changes in active Thyroid ophthalmopathy (TO) patients due to thyroid disease using Optical Coherence Tomography An-giography (OCTA). Methods: Forty-six (34 females and 12 males) active TO patients and 41 (28 females and 13 mal...

A 43-year-old female patient presented with complaints of decreased vision in both eyes. Her medical history revealed the diagnosis of metastatic breast cancer. She was treated with chemotherapy, and whole-brain, manubrium sterni, and right chest wall radiation therapy. Best-corrected visual acuity (BCVA) was 20/200 and 20/160 in the right and left...

Background: To evaluate microvascular morphological characteristics of the retina and optic disc (OD) in retinal vein occlusion (RVO) patients using optical coherence tomography angiography (OCTA), compare the results to age- and gender-matched healthy subjects, and determine correlations between OCTA parameters and best-corrected visual acuity (B...

Amaç YouTube üzerinden yayınlanan videolarda kornea nakli hakkında verilen bilgilerin ne denli güvenilir olduğunu değerlendirmek. Yöntemler YouTube üzerinden video arama motoruna “kornea nakli” yazıldıktan sonra ekranda beliren ilk 100 video 04.03.2022 tarihinde listelenmiştir. Yükleme tarihi, yayın süresi, toplam izlenme sayısı, günlük izlenme ora...

Background To investigate changes in retinochoroidal microvascular morphology after caffeinated versus decaffeinated coffee consumption in age- and gender-matched healthy individuals using optical coherence tomography (OCT) and OCT angiography (OCTA) Methods In this prospective, randomized clinical study, a staff member in charge of record keeping...

Background: The aim of this study was to evaluate the most common underlying genetic and clinical etiologies of retinitis pigmentosa (RP) disease in our geographical area. Material and Method: In our archive, there are about 3000 patients who applied to our clinic between the years 2015-2021. The files of approximately 700 patients with a definitiv...

INTRODUCTION: The purpose of this single-centered internet-based study was to determine the readability of COVID-19-related ocular findings on Turkish websites. METHODS: TThe first 33 websites that appeared when searching Google for phrases like "Does coronavirus affect the eye," "Coronavirus eye findings," COVID-19-related ocular manifestations,"...

Objective: To assess polycythaemia vera (PV)-related retinal microvascular morphological changes using optical coherence tomography angiography (OCTA). Material and Methods: In this cross-sectional case-control study, 30 PV patients (Group 1) and 30 healthy individuals (Group 2) underwent a comprehensive ophthalmological examination, followed by...

Purpose To investigate changes in the retinal and optic disc (OD) morphology in prolactinoma patients without optical chiasmal compression and/or visual field defects using optical coherence tomography angiography (OCTA). Methods In this cross-sectional imaging study, 16 consecutive prolactinoma patients (group 1, 32 eyes) and 15 age- and gender-m...

Background To investigate retinal microvascular morphological changes in previously COVID-19 infected patients using optical coherence tomography angiography (OCTA), and compare the findings to age- and gender-matched healthy subjects. Methods In this cross-sectional study, OCTA findings (6.0 × 6.0 mm scan size and scan quality index ≥7/10) from p...

Objective: The aim of the study was to evaluate retinal and choroidal microvascular morphological changes in non-ocular sarcoidosis (NOS) patients using optical coherence tomography angiography (OCTA) and compare the results to age- and gender-matched healthy individuals. Patients and methods: This study included 37 NOS patients (group 1, 37 rig...

Aim: This study aimed to investigate the effects of music intervention applied in two different periods Before intravitreal injection (IVTI) on anxiety, pain perception, vital signs, andsatisfaction in patients receiving intravitreal injection..Methods: This randomized controlled study was conducted with a total of three groups including two music...

Purpose: To investigate effect of iron deficiency anemia (IDA) on macular and radial peripapillary capillary (RPC) vascular changes by optical coherence tomography angiography (OCTA). Methods: Thirty-three patients with IDA and 33 healthy controls were enrolled in the study. Foveal avascular zone (FAZ) area, macular superficial capillary plexus...

Aims: The aim of this study was to evaluate the cardiac autonomic functions of individuals with asymptomatic diabetic retinopathy (DR) and no obvious heart disease by heart rate turbulence (HRT) and heart rate variability (HRV) analysis. Methods: A total of 72 patients with Type II Diabetes Mellitus: 20 non-retinopathic (NRDM), 26 non-proliferat...

Purpose: To compare the thickness of macula, choroid, and peripapillary retina nerve fiber layer (RNFL) in patients with inflammatory bowel disease (IBD). Materials and Methods: 57 patients with IBD and 29 healthy individuals evaluated for this corss-sectional study. Macular thickness (MT), RNFL thickness, and choroidal thickness (CT) were measur...

Aims: To investigate consequences of seasonal allergic conjunctivitis (SAC) on the ocular anterior and posterior segment parameters. Materials and methods: Forty healthy participants (mean age: 25.90 ± 5.7 years, 20 females, 20 males) and 40 patients with SAC (mean age: 26.20 ± 5.7 years, 20 females, 20 males) were included in this prospective s...

Background/Aim This study aimed to evaluate the comprehensibility of the consent forms used for interventional procedures in the ophthalmology clinic of a university hospital and to determine which texts could be read according to patient age and education level. Materials and methods Forty separate consent forms used as the standard for various in...

Objective: Branch retinal vein occlusion (BRVO) is the most common retinal vascular disease following diabetic retinopathy. Pathogenesis of BRVO is multifactorial and could not be clarified enough yet. As BRVO is a disease that goes with thrombosis and inflammatory processes, inflammatory markers could help to predict the risk of BRVO. The aim of t...

Purpose To evaluate the effects of metformin alone and combined treatment with metformin and an SGLT2 inhibitor on retinal microvascular morphology using optical coherence tomography angiography (OCTA) in isolated type 2 diabetes mellitus (DM) patients with HbA1c above the expected target (> 7%). Methods Fifty patients with isolated DM, 7% < HbA1c...

Aim: To evaluate clinical results of primary repair with silicone tube intubation after traumatic injury of lacrimal canalicular system. Materials and Methods: Fifteen patients applied to ophthalmology clinic at Afyonkarahisar Health Sciences University between January 2010 and May 2020 with traumatic injury of lacrimal canaliculi were included in...

Purpose: To evaluate the effects of a single dose of oral 5-mg tadalafil on macular microcirculation as measured using optical coherence tomography (OCT) and angiography (OCTA) in healthy volunteers. Methods: Twenty-two healthy, middle-aged, sexually active, and male health care worker volunteers were included in this prospective study. All volunt...

Background: This report describes a case with paracentral acute middle maculopathy revealing a giant aortic aneurysm. Case Description: A 41-year-old man presented with unilaterally unexplained sudden vision loss in the left eye. Fundoscopy revealed a slightly pale r -26etinal reflex in the superior retinal hemifield. SDOCT revealed blurred boundar...

BACKGROUND Tea, second only to water, is one of the most regularly consumed drinks in the world. Its potentially beneficial effects on general health may be enormously important. Optical coherence tomography angiography (OCTA) now allows clinicians to examine the acute retinal morphological changes caused by black tea consumption. The purpose of th...

Background: Evaluation of anatomical and functional recovery of the retina after aflibercept therapy in neovascular age-related macular degeneration MATERIALS AND METHODS: This prospective study enrolled 33 eyes of 33 naive age-related macular degeneration patients with an average age of 69 (55-82) years. Following a thorough ophthalmological exam...

Background: This study intended to illustrate a rare case of pyogenic granuloma (PG) in retinal vein occlusion (RVO) patient after dexamethasone (DEX) implant therapy. Case Description: A 58-year-old female who underwent DEX implant therapy a month ago due to RVO presented with a mass in her right eye. Anterior segment analysis revealed a slowly en...

Abstrct Purpose To analyze the macular microvascular changes after panretinal photocoagulation (PRP) in patients with non-proliferative diabetic retinopathy (NPDR) and a large foveal avascular zone area, using optical coherence tomography angiography. Methods Twenty-four eyes of 24 patients with peripheral ischemia, superficial foveal avascular z...

Purpose To analyze the vascular morphology changes after consumption of Ginkgo biloba in healthy volunteers by optical coherence tomography angiography (OCTA). Methods Sixty healthy volunteers without systemic and ocular disease were included in this prospective pilot study. After receiving the informed consent of the volunteers, Ginkgo biloba ext...

PurposeTo evaluate anatomical and neuroretinal functional aspects in patients with diabetic macular edema (DME) after intravitreal anti-vascular endothelial growth factor (VEGF) therapy, in particular aflibercept. Materials and methodsThis prospective single-centered interventional study was performed at Afyonkarahisar Health Science University Fac...

Purpose Investigation of retinal morphological alterations in patients with polycythemia vera (PV) using optical coherence tomography angiography (OCTA). Materials and Methods Thirty PV patients (group 1) who were followed-up at Afyonkarahisar Health Sciences University Hospital, Department of Hematology, and 30 normal subjects (group 2) who applie...

Purpose: This study was conducted to evaluate visual function and changes in the central macular thickness of patients with unresponsive neovascular age-related macular degeneration who were switched from ranibizumab (Lucentis®) to aflibercept (Eylea®) treatment at 30 months. Methods: This retrospective study examined patients with neovascular age...

PurposeTo investigate changes in macular and panretinal neuroretinal functions by electroretinographic examinations in eyes with diabetic macular edema (DME) treated with intravitreal ranibizumab.Material and methodsSixty-four patients with DME were included in this prospective study. Patients were treated with ranibizumab injection according to th...

Aim: To investigate the effect of intravitreal dexamethasone implant on central foveal thickness and choroidal thickness in retinal vein occlusion. Materials and methods: Clinical records and optical coherence tomography (OCT) scans of 41 naïve patients with retinal vein occlusion (RVO), who were initially treated with intravitreal dexamethasone...

Age-related macular degeneration (AMD), which can result in central vision loss, is among the leading causes of blindness worldwide. The beginning of the anti-vascular endothelial growth factor (anti-VEGF) era has revolutionized the treatment of AMD. The effi cacy of anti-VEGFs (bevacizumab, ranibizumab and afl ibercept) has been proven in importan...

OBJECTIVE: It was aimed to find out the factors affecting the operation time in patients undergoing pterygium surgery and to determine the precautions that can be taken. MATERIAL AND METHODS: The study included 53 patients who were operated for pterygium in our clinic between January 2014 and February 2017. The reasons for delaying the surgery we...

Purpose: To determine the levels of serum oxidative, antioxidative markers and inflammatory cytokines in patients diagnosed with diabetic macular edema (DME) whose hyperreflective spots (HRS) were detected by optical coherence tomography (OCT). Methods: In this prospective cross-sectional clinical study included a total of 88 patients; 31 patients...

Lens-induced uveitis is a rare form of uveitis. It is an autoimmune phenomenon secondary to lens proteins that go out of the lens capsule due to exogenous or iatrogenic (surgical) trauma. The classic history and eye examination findings are typical for diagnosis. For the treatment, surgery is usually chosen in the forefront.Intraocular lens-induced...

Objectives: The aim of this study was to histopathologically compare patients with and without diabetes mellitus who underwent pterygium excision. Methods: In this retrospective case-control study, 60 patients with a history of pterygium excision were divided into 2 groups: those with DM and those without DM. Histopathological findings (squamous...

Clinical relevance: Panretinal photocoagulation, an important treatment method in diabetic retinopathy, can affect macular pigment optical density, which has protective and antioxidant properties. As a result of this effect, the retina may become more sensitive to high-energy visible light. Background: The current study assesses the effect of pa...

This report describes the therapeutic effects and outcomes of an accidental injection of an intralenticular sustained-release dexamethasone implant (Ozurdex®) in three patients with diabetic macular edema. All three patients underwent accidental injections of sustained-release intravitreal dexamethasone implants into the crystalline lens by the sam...

Amaç: Bu çalışmada oküler tutulumu olmayan sarkoidoz hastaları ile sağlıklı bireylerde maküler koroid kalınlığının karşılaştırılması amaçlanmıştır.Gereç ve Yöntemler: Bu retrospektif çalışmaya oküler tutulumu olmayan 25 sarkoidoz hastasının 25 gözü ile sağlıklı 25 bireyin 25 gözü dahil edildi. Hasta dosyalarından rutin oftalmolojik muayene bilgiler...

PURPOSE: Evaluation of retinal and choroidal changes after energy drink consumption by optical coherence tomography and optical coherence tomography angiography. METHODS AND MATERIAL: Forty-two healthy volunteers with neither systemic nor ocular diseases were enrolled in the study. The energy drink (250 ml Red Bull energy drink) was provided to all...

Background The purpose of this study was to report the effects of smoking on retinal vascular parameters. Methods In this cross‐sectional study design, 24 smokers were included as a study group and 26 age‐ and sex‐matched non‐smokers as a control group. A detailed ophthalmic examination including review of medical history, visual acuity testing, i...

Aim: In this study, we aimed to evaluate the effects of Ramadan fasting on retinal vascular and anterior chamber parameters. Materials and Methods: The study included 60 healthy eyes of 30 volunteers (15 males, 15 females) who visited our clinic between May and July 2017. We performed measurements of intraocular pressure (IOP), anterior chamber vo...

INTRODUCTION: The aim of this study was to assess the intraobserver repeatability of central corneal thickness, peripheral corneal thickness (PCT), keratometry values (steep K, flat K), white-to-white diameter, and anterior chamber depth using the Sirius topography device (Costruzione Strumenti Oftalmici, Florence, Italy) in healthy eyes. METHODS:...

Purpose: The aim was to assess the ganglion cell complex (GCC) thickness, retinal nerve fiber layer (RNFL) thickness and optic disk features in the affected eyes (AE) and unaffected fellow eyes (FE) of subjects with unilateral nonarteritic anterior ischemic optic neuropathy (NAION) and to compare with healthy control eyes (CE) using spectral domai...

We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects and differences on age-related macular degeneration (AMD) and diabetic retinopathy (DRP). A retrospective case-control study was conducted between January 2017 and January 2018 on a total of 114 patients (84 DRP, 30 AMD) and 24 age and sex-...

Purpose: To evaluate the effects of intravitreal aflibercept (IVA) treatment on retinal vein parameters and choroidal thickness used in the treatment of diabetic macular edema (DME). Methods: This retrospective study administered Afyonkarahisar Health Sciences University Department of Ophthalmology. Twenty-nine patients who were diagnosed with naiv...

Background To compare the repeatability and agreements of central corneal thickness measurements of healthy individuals obtained by Scheimpflug‐Placido topographer (Sirius), anterior segment spectral domain optical coherence tomography (Spectralis) (AS‐OCT), optical biometry (AL‐Scan) and ultrasonic pachymetry. Methods Sixty‐four eyes of 32 subjec...

Objectives: Aim of this study is to investigate the effect of intravitreal aflibercept therapy in an 18-month period in patients with recurrent neovascular age-related macular degeneration resistant to intravitreal ranibizumab. Methods: This is a prospective study of eyes with neovascular age-related macular degeneration switched to intravitreal af...

Aim: To evaluate the long-term sucess rate of laser-assisted dacryocystorhinostomy (L-DCR) in patients with nasolacrimal duct obstruction (NDO). Methods: Forty-one eyes of forty patients aged between 21-85y (mean 56.7y) who underwent L-DCR for the treatment of NDO were included in this retrospective, non-randomized study. The follow-up time was...

Purpose. To determine the effect of proparacaine 0.375%-sodium fluorescein 0.25% eye drop mixture and fluorescein strip on anterior segment parameters commonly used in routine ophthalmology practice. Methods. 115 healthy volunteers without any systemic or ocular disease were divided into two groups. 57 volunteers were in the proparacaine 0.375%-sod...

Anterior chamber dislocation of an Ozurdex (Allergan plc, Dublin, Ireland) implant from the vitreous cavity is unusual. The risk factors for dexamethasone implant migration into the anterior chamber include a defective posterior lens capsule, aphakia, and a prior history of pars plana vitrectomy. Presently described is a case of corneal toxicity oc...

Aims and objectives: The aim of the study was to analyze and quantify the pattern of corneal astigmatism in Caucasian cataract surgery patients using a new optical biometer (axial length [AL] Scan, NIDEK Co., Gamagori, Japan). Patients and methods: The datasets of cataract surgery patients acquired between March 1, 2014, and April 15, 2016, were...

Purpose: The purpose of this study is to evaluate anterior segment measurements obtained using CSO Sirius Topographer®(CSO, Firenze, Italy) and Nidek Axial Length (AL)-Scan®(Nidek CO., Gamagori, Japan). Methods: A total of 43 eyes of 43 patients were included in this prospective study. The central corneal thickness (CCT), anterior chamber depth...

Objective: We aimed to present the epidemiological evaluation of our patients who developed corneal perforating eye injuries with trauma reasons. Material and Method: The records of 80 patients treated for corneal perforation between January 2003 and May 2014 we reanalyzed retrospectively at Afyon Kocatepe University Medical Faculty Department of O...

Purpose: We aimed to demonstrate the reasons of demographic factors for the delay of operation time in mature cataract patients and to determine the measures to be taken to prevent delay. Materials and Method: The study involved 98 patients operated by phacoemulsification in Afyon Kocatepe University Hospital from January 2014 to December 2016. Th...

To carry out an ophthalmological investigation on a 61year-old women with isolated foveal hypoplasia. A full ophthalmological examination and optical coherence tomography (OCT) was performed. Her eye examination was normal except foveal hypoplasia. Fundus examination, showed classic signs of foveal hypoplasia. We report a case of isolated foveal hy...

Nöroretinit, yavaş yavaş başlayıp bir hafta kadar sonra ağırlaşan tek taraflı ağrısız görme kaybı ile presente olur. Genellikle tek taraflı görme kaybı, optik disk ödemi ve eksudatif makulapati ile karakterize bir patolojidir. Görme genelde 6-12 ay içinde normale döner. %25 idiopatik iken %60’ında neden kedi tırmığı hasalığıdır. 35 yaşında erkek ha...

Purpose: To compare the effects of alfuzosin hydrochloride and tamsulosin hydrochloride on choroidal thickness (CT) and pupil diameter (PD) sizes in patients with benign prostatic hyperplasia. Subjects and methods: Sixty-three men patients with newly diagnosis of benign prostatic hyperplasia were randomly assigned to either alfuzosin hydrochloride...

Objectives: To determine factors influencing compliance in patients with neovascular age-related macular degeneration (n-AMD) undergoing intravitreal anti-vascular endothelial growth factor (VEGF) therapy. Materials and Methods: The files of n-AMD patients recommended treatment with ranibizumab were reviewed retrospectively. The treatment regimen w...

Aim: Comparison of external dacryocystorhinostomy (DSR) and transcanalicular multidiod laser dacryocystorhinostomy (TK-DSR) results in acquired nasolacrimal duct obstruction cases. Method: Data of patients diagnosed with acquired nasolacrimal duct obstruction and operated were retrospectively screened. The results of external DSR surgeries in 49 ey...

Purpose: To evaluate the macular and peripapillary choroidal thickness and retinal volume in prediabetes. Material and Methods: This prospective comparative study included 53 patients with prediabetes and 53 age- and sex-matched healthy subjects. Only right eyes were selected. Choroidal thicknesses (CT) and retinal volume were measured by optical c...

Purpose To evaluate and investigate the effects of α1-adrenoceptor antagonist alfuzosin hydrochloride on anterior and posterior segment findings using Sirius Scheimpflug/Placido photography-based topography system and enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Methods This prospective study was performed with ne...