Mustafa Mahmut Barış

• Doctor of Medicine
• Dokuz Eylül University

The aim of the study; to investigate whether there is a relationship between body mass index (BMI), waist circumference, and abdominal subcutaneous adipose tissue and the skin-epidural space distance measured by ultrasonography.

Purpose: Atherosclerosis (AS) related diseases are the most common causes of mortality worldwide. N-Nitro-L-Arginine Methyl Ester Hydrochloride (L-NAME)-induced endothelial dysfunction (ED) and AS models require invasive methods for diagnosis. We aimed to establish noninvasive ultrasonography (USG) model for evaluating ED and AS in rats. Matherial...

Background Signal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts and alveolar type II cells (AT-II) and is thought to contribute to fibrosis in lung tissue. Significant JAK/STAT activation was demonstrated in fibroblasts, skin biopsies and scleroderma animal models of patients with Systemic Sclerosis (S...

Objective: To review the presentation characteristics, clinical and hormonal evaluations, and histopathological results of patients with adrenal lesions over a period of 21 years and to evaluate the changes across the two decades. Methods: This single-center, retrospective study included 1003 patients with adrenal lesions who presented to our de...

Magnetic Resonance Imaging (MRI) is an exceptional diagnostic tool known for its ability to provide superior soft tissue contrast. Despite its proven efficacy, traditional MRI methods have some inherent limitations, including relatively longer scan times and the requirement for specialized expertise in data analysis. These factors can, at times, cr...

Autonomous cortisol secretion (ACS) of an adrenal incidentaloma (AI) is associated with mild cortisol excess that could result in poor metabolic and cardiovascular outcomes. The biological activity of glucocorticoids depends on the unbound, free fraction. We aimed to evaluate plasma free cortisol (FC) concentrations in patients with ACS in this cro...

OBJECTIVE: Infective endocarditis (IE) is defined as infection of the endocardial surface of the heart. Updates are needed in the diagnosis and treatment of IE, as well as in animal models of IE. Based on this need, a new model of infective endocarditis induced by S. aureus was described in our study. METHODS: This study was performed on 7 Wistar a...

Background Infective endocarditis (IE) is an infection of the heart’s endocardial surface. In recent years, nuclear imaging methods have gained importance in the diagnosis of IE. The present study aims to investigate the imaging potential of 99mTc-labeled vancomycin ( 99mTc-Vancomycin) as a new agent that would enable the diagnosis of IE in its ear...

Segmentation of abdominal organs has been a comprehensive, yet unresolved, research field for many years. In the last decade, intensive developments in deep learning (DL) introduced new state-of-the-art segmentation systems. Despite outperforming the overall accuracy of existing systems, the effects of DL model properties and parameters on the perf...

Background The aim of this study was to investigate the effects of bivalirudin on endothelial cell proliferation and neointimal hyperplasia in a rabbit carotid artery model.Methods“New Zealand rabbits (n = 12)” weighing 2–3 kg were randomly divided into two groups. Arteriotomy was performed to the rabbit carotid artery and closed with continuous su...

Purpose: Because of the widespread use of CT in the diagnosis of COVID 19, indeterminate presentations such as single, few or unilateral lesions amount to a considerable number. We aimed to develop a new classification and structured reporting system on CT imaging (COVID-19 S) that would facilitate the diagnosis of COVID-19 in the most accurate wa...

Background DICOM standard does not have modules that provide the possibilities of two‐dimensional Presentation States to three‐dimensional (3D). Once the final 3D rendering is obtained, only video/image exporting or snapshots can be used. To increase the utility of 3D Presentation States in clinical practice and teleradiology, the storing and trans...

[https://arxiv.org/abs/2001.06535] Segmentation of abdominal organs has been a comprehensive, yet unresolved, research field for many years. In the last decade, intensive developments in deep learning (DL) have introduced new state-of-the-art segmentation systems. Despite outperforming the overall accuracy of existing systems, the effects of DL mod...

Purpose: To investigate the reproducibility of LIRADS v2014 and contribute to its widespread use in clinical practice. Material and methods: This retrospective, single-centre study was conducted between January 2010 and October 2015. A total of 132 patients who had dynamic magnetic resonance imaging (MRI)/computed tomography (CT) images in the P...

Purpose: To compare the accuracy and repeatability of emerging machine learning based (i.e. deep) automatic segmentation algorithms with those of well-established semi-automatic (interactive) methods for determining liver volume in living liver transplant donors at computerized tomography (CT) imaging. Methods: A total of 12 (6 semi-, 6 full-aut...

Background To evaluate ocular pulse amplitude (OPA) in patients with carotid artery stenosis (CAS) using the Pascal dynamic contour tonometer (DCT). Methods Consecutive patients who underwent ultrasound Doppler examination of the carotid artery for the suspicion of CAS were prospectively enrolled in the study. Each patient underwent a complete ocu...

Purpose We developed a heart atlas for breast radiation therapy and evaluated the influence of education on intra and inter-observer similarity, and cardiac dose reporting. Materials and methods The data of 16 left breast cancer patients were analyzed. Eight observers delineated heart and cardiac subunits [left (LCA) and right (RCA) coronary arter...

Although the endothelial dysfunction is related with tumor development, there is no consensus on the suppressive or supportive effect on tumor growth. The goal of the present study was to evaluate endothelial dysfunction related factors in animal breast cancer model that was developed by administrating endothelial nitric oxide synthase blocking age...

Increased intraabdominal visceral fat plays an important and etiologic role in metabolic disorders, cardiac diseases and increased all-cause mortality (1,2,3,4). Abdominal fat measurement with quantitative computed tomography (QCT) is a useful tool for evaluation of metabolic disorders (5,1,6,7,8). Several studies revealed that visceral fat area me...

Objective: Autonomous cortisol secretion of adrenal incidentalomas (AIs) is associated with poor cardiovascular outcome. Because centripetal obesity is a cardiovascular risk factor, we aimed to investigate whether autonomous cortisol secretion is associated with increased visceral fat accumulation. Design: Retrospective cohort study. Patients:...

Purpose: Low plasma corticotropin is considered a useful parameter for the diagnosis of subclinical hypercortisolism in patients with an adrenal incidentaloma. However, immunoassays are vulnerable to interference from endogenous antibodies. In this study, subjects who underwent Hypothalamus-pituitary-adrenal axis evaluation for the assessment of s...

Background: Chest radiography is the initial choice for thoracic imaging. However, the wide availability of computed tomography (CT) has led to a substantial increase in its use in the emergency department (ED). We evaluated the utility of chest CT after a chest X-ray in patients presenting to the ED with non-traumatic thoracic emergencies, and de...

Backgrounds Pulmonary arterial hypertension (PAH) was previously considered an illness that affects mostly the young, but now it is also increasingly recognized in the elderly. The aim of this study was to compare the features of elderly versus younger patients diagnosed with PAH, and to define the prognostic factors which affect their long-term su...

Objective: Acute coronary syndrome and pulmonary thromboembolism (PTE) are the pathologies to be considered in the differential diagnosis of acute aortic syndromes (AAS). However, it is not uncommon many thoracoabdominal emergencies imitating AAS. In this study, we aimed to evaluate the results of computed tomography angiography (CTA) images obtain...

Perforation of the gastrointestinal tract by accidently ingested foreign bodies is rare, occurring in less than 1% of the patients. Fish bones are the most common foreign bodies leading gastrointestinal tract perforation due to their elongated shape end sharp ends. Preoperative diagnosis of the gastrointestinal tract perforation by foreign body is...

Introduction: The differentiation of metastatic and primary brain tumors with certainty is important since clinical management and treatment of these two types of tumors are radically different. The purpose of the present study was to evaluate the effect of peritumoral edema volume, tumor volume and mass effect of tumor on differential diagnosis o...

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs. Dokuz Eylul Unive...

A 38-year-old woman presented with a 12-month history of subjective weakness and pain in her legs. Thoracolumbar MRI revealed two spinal intradural cystic lesions at T5-6 and T11 levels, respectively. The lesion located at the T5-6 level was heterogeneously hyperintense on T2-weighted images and heterogeneously hypointense on T1-weighted images. Th...

Situs inversus is a rare congenital abnormality involving partial or complete transposition of the thoracic or abdominal viscera. In situs inversus totalis, both the thoracic and abdominal viscera are transposed. The incidence of this condition is 0.01% to 0.02%. Bronchopulmonary sequestration (BPS) is a rare congenital abnormality of the respirato...

Introduction: Natural history of adrenal incidentalomas has not been totally understood. Current data from subjects with adrenal incidentalomas demonstrated an increased rate of metabolic disturbances and cardiovascular risk. It has been shown that subjects with subclinical cortisol excess were more susceptible to diabetes, hypertension, and obesit...

Subtle changes in hypothalamic- pituitary-adrenal (HPA) axis of subjects with nonfunctioning adrenal adenoma may be associated with endothelial alterations. We sought to investigate endothelial function, visceral adiposity and osteoprotegerin (OPG) and interleukin- 18 (IL-18) levels in subjects with non-functioning adrenal adenomas. The adenoma gro...

Circulating levels of osteoprotegerin (OPG) have been shown to be increased in patients with cardiovascular disorders and diabetes. The aim of this study was to determine serum OPG levels in women with previous gestational diabetes (GDM), and to investigate the relationship between OPG and carotid intima media thickness (IMT) and circulating cardio...