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Publications (10)
The conventional approach in the tablet formulation of acetaminophen (ACM) suggests the use of five or more different excipients in a wet granulation tableting process. The use of many excipients in tablet formulation may negatively create excipient-excipient interactions, excipient-drug interactions, exaggerated product side effects, and high drug...
In this study, the effect of anhydrous calcium phosphate, an efflorescent pharmaceutical powder of reduced moisture content, ideal for moisture-sensitive materials; and the comparative binding effects of maize starch, polyvinylpyrrolidone and gelatin were investigated in the tablet formulation of the deliquescent crude extract of the leaves of Vern...
Context: Leaves of Vernonia galamensis (Asteraceae) have been used for the treatment of diabetes mellitus in folk medicine in northern Nigeria for ages. The crude extract of the leaves is deliquescent and usually stored in airtight desiccators. Attempts to use common diluents such as lactose, starch, and magnesium carbonate for tablet formulation o...
The powdered leaf of Vernonia galamensis (Asteraceae) is a herbal drug used in the treatment of diabetes mellitus in folk medicine in northern Nigeria. The crude aqueous extract of the leaves is deliquescent and usually stored in airtight desiccators. Efforts to use common diluents such as lactose, starch, and magnesium carbonate for tablet formula...
Tablet formulation of the crude aqueous extract of the leaves of Vernonia galamensis (Asteraceae), used for the treatment of diabetes in folk medicine was carried out using the wet granulation method. The dried extract is deliquescent in nature; therefore, efflorescent diluents were carefully selected for the formulation. The purpose of this study...
Introduction: The dry powdered leaf of Vernonia galamensis (Asteraceae) has been used by traditional herbalists in northern Nigeria to treat diabetes mellitus. However, medicinal plants used in folk medicine have no standard dose or acceptable method of formulation. In this study therefore, the leaves of Vernonia galamensis (Asteraceae) were extrac...
Leaves of Vernonia galamensis (Asteraceae) have been used for the treatment of diabetes mellitus in folk medicine in northern Nigeria for ages. The crude extract of the leaves is deliquescent and usually stored in airtight desiccators. Efforts to use common diluents such as lactose, starch, and magnesium carbonate for tablet formulation of the extr...
A decoction of the leaves of Vernonia galamensis (Asteraceae) has been used in folk medicine for the treatment of diabetes mellitus. But because folkloric medicines have no standard dose or acceptable method of formulation, attempts have been made by some scientists to formulate crude plant extracts into tablets. The crude leaves ex-tract of Vernon...
