Muna Sameer Saeed Al-rawi

University of Baghdad · Department of Chemistry

2-hydrazinylbenzo[d]thiazole compound [1] is produced from reaction of 2-mercapto-benzothiazole with hydrazine hydride in ethanol. Compound [1] reacted with maleic anhydride in DMF to produce (Z)-4-(2-(benzo[d] thiazol-2yl) hydrazinyl)-4-oxobut-2-enoic acid [compound (2)]. While the treatment of compound [2] with the ammonium persulfate (NH4)2S2O8...

The new compounds of 3-substituted phenyl-5-(3,4,5-trihydroxyphenyl)-4H-pyrazole-4-carbaldehyde [III]a-e were synthesized by reacting various hydrazones derived from galloyl hydrazide with different substituted aromatic ketones using phosphoryl trichloride in dimethylformamide as a solvent. The newly synthesized derivatives were elucidated using FT...

The new 1,3-Oxazepine derivatives (IVa-d) were manufactured from the response of N-Arylhydrazone (III) based on Mefenamic acid with various cyclic carboxylic acid anhydrides such as (succinic, maleic, phthalic, and 3- nitrophthalic) anhydride by using dry benzene under reflex via (2+5) cycloaddition reaction. These compounds 1,3-Oxazepine (IV) were...

The new 1,3-Oxazepine derivatives (IVa-d) were manufactured from the response of N-Arylhydrazone (III) based on Mefenamic acid with various cyclic carboxylic acid anhydrides such as (succinic, maleic, phthalic, and 3- nitrophthalic) anhydride by using dry benzene under reflex via (2+5) cycloaddition reaction. These compounds 1,3-Oxazepine (IV) were...

Thiazolidine-4-one derivatives (IV)a,b containing 1,2,4-triazole rings linked to 3,4,5-trihydroxyphenyl moiety were designed, synthesized, and biologically evaluated for the antibacterial/antifungal activities. These derivatives (IV)a,b were achieved from many sequence reactions. A multistep reaction protocol was used that began with the first step...

A new series of amic acids [III]a-e and N-substituted-imides [IV]a-e containing a 1,2,4-triazole moiety were designed, synthesized, and evaluated for its antimicrobial activities and cytotoxic effects. The structural modifications at position 3 of the 4-amino-5-mercapto-4H-1,2,4-triazole ring (linked to a bioactive 3,4,5-trihydroxyphenyl moiety) we...

To further study novel N-aceyl, N-thiourea and imidazole derivatives were synthesized. We used a multi-step reaction protocol that began with symmetrical 4-amino- 1,2,4-Triazole [I]. The synthesized compounds were characterized on the spectroscopic data and their physical properties. Also, we studied the anti-bacterial activity of the prepared comp...

https://doi.org/10.31838/ijpr/2020.SP2.331

American Chemical Society / Iraq chapter , The online scientific lecture on FCC Platfrorm

Researcher Academy On Campus Certificate of Attendance This certifies that Muna Al-rawi has attended the following When do I need to pay an APC to get published? [60 Minutes] at Egyptian Knowledge Bank, on Tuesday 08 June, 2021 Presented by Khalid Shalan Core Research Solutions Consultant-Elsiver

By condensation of benzaldehyde with thiourea in absolute ethanol in the presence of glacial acetic acid as a catalyst, the Schiff base(1- benzylidenethiourea)[I] was synthesized by synthesis of 4-(3- benzylidenethioureido)-4-thioxobut-2-enoic acid compound[II] by reaction of maleic anhydride with schiff base [I] in DMF. When treating compound [II]...

Certificate of Proudly Presented from University of Basrah- College of Scinence, Department of Chemistry Teaching, held on 4-11- 2021. Topic: Plastic and Enviromental Protection from Chemical Waste Workshop.

Certificate of Excellence in Reviewing No: SDI/HQ/PR/Cert/65146/MUN , Journal of Advances in Medical and Pharmaceutical Sciences

Certificate of Excellence in Reviewing in (European Journal of Medicinal Plants)

Certificate of Excellence in Reviewing on (International Research Journal of Pure and Applied Chemistry)

The current study included the separation of three alkaloid compounds from Anastatica Hierochuntica and studied the effect of the these compounds on cancerous cells , specifically liver cancer it was found that compound number one is the most influential or inhibiting at 50 percent followed by compound number three when using concentration of 400 μ...

The current study included the separation of three alkaloid compounds from Anastatica Hierochuntica and studied the effect of the these compounds on cancerous cells , specifically liver cancer it was found that compound number one is the most influential or inhibiting at 50 percent followed by compound number three when using concentration of 400 μ...

Synthesis 1,3,4-oxadiazole derivatives and study their liquid crystals.

ound was precipitated in aceton , filtered and washed with acetone to remove the unreacted acid and then dried at 60°C in oven for24hrs. Synthesis of O,N chitosan derivatives [26-31](16) : (0.01mol) of chitosan was marinated in 50 mL CHCl3 and pyridine (1:1) for 20h. , (0.01mol) of compounds[14-19] was added to them under water –ice bath, the mixtu...

In the present research, synthesis and characterization of novel heterocyclic compounds substituted chitosan moieties was achieved. Bis Schiff base [1] was utilized as a commencing material for the synthesis method. Schiff base[1] was achieved from the reaction of two mole of 2-amino-5-mercapto-1,3thiadiazole with one mole of terephthalaldehyde in...

A series of amic acid derivatives of mefenamic acid were synthesized with the aim of inhibitting topical gastrointestinal toxicity of mefenamic acid. The key intermediate amic acid (III) was prepared from the reaction of acid hydrazid of mefenamic acid(II) with phthalic anhydrides in dry actone. The new type of imide compound (IV) was dehydrated th...

2-(1-(naphthalen-2-yl) ethylidene) hydrazine-1-carbothioamide [I] with ethyl α-chloroacetate in the presence of fused CH3COONa. The new 2-thioxo-imidazlidin-4-one derivatives containing heterocyclic unit, five, and seven-member ring\ were successfully formed, such as imidazoline-4-one, tetrazole, thiazolidin-4-one, and 1,3-oxazepinerings. The synth...

A new ligands(modifier polymers) L1, L2, L3 , L4 and L5 were prepared according to method [8] by reaction of polyvinyl alcohol(PVA) withi(acid chloride)[1]a or [2,3]a,b in dimethyl formamide. The Ligands were characterized by (FT-IR), (UV- Vis) and (1H-NMR) spectra some of them. Synthesis some transition metals complexes of these ligands and descri...

A new ligands(modifier polymers) L1, L2, L3 , L4 and L5 were prepared according to method [8] by reaction of polyvinyl alcohol(PVA) withi(acid chloride)[1]a or [2,3]a,b in dimethyl formamide. The Ligands were characterized by (FT-IR), (UV-Vis) and (1 H-NMR) spectra some of them. Synthesis some transition metals complexes of these ligands and descri...

A new ligands(modifier polymers) L1, L2, L3 , L4 and L5 were prepared according to method [8] by reaction of polyvinyl alcohol(PVA) withi(acid chloride)[1]a or [2,3]a,b in dimethyl formamide. The Ligands were characterized by (FT-IR), (UV- Vis) and (1H-NMR) spectra some of them. Synthesis some transition metals complexes of these ligands and descri...

A new ligands(modifier polymers) L1, L2, L3 , L4 and L5 were prepared according to method [8] by reaction of polyvinyl alcohol(PVA) withi(acid chloride)[1]a or [2,3]a,b in dimethyl formamide. The Ligands were characterized by (FT-IR), (UV-Vis) and (1 H-NMR) spectra some of them. Synthesis some transition metals complexes of these ligands and descri...

he aldol condensation of 2-acetylnaphthalene with 9-anthracene carboxaldehyde afforded α , β -unsaturated keton (1) . New heterocyclic compounds containing: cyclohexenone[2], indazole[3], pyrimidinethion [4], thiazolo fused pyrimidine[5], isoxazoline[6], substituted pyrazoline[7] a-d and pyrimidinone[8] rings system were synthesized from α ,...

A new Schiff base [I] was prepared by refluxing Amoxicillin trihydrate and 4-Hydroxy- 3,5-dimethoxybenzaldehyde in aqueous methanol solution using glacial acetic acid as a catalyst. The new 1,3-oxazepine derivative [II] was obtained by Diels- Alder reaction of Schiff base [I] with phthalic anhydride in dry benzene. The reaction of Schiff base [I] w...

The new Schiff bases derived fro m D-erythroascorbic acid containing heterocyclic unit were synthesized by condensation of D-erythroascorbic acid with aro matic amine (containing 1,3,4-o xad iazole or 1,3,4-thiad iazole unit) in dry benzene using glacial acetic acid as a catalyst. D-erythroascorbic acid[IV] was synthesized by four steps (Scheme 1),...

The present study envisaged utilizing 4-aminoantipyrine as key intermediate for the synthesis of some new derivatives bearing anti-bacterial and anti-cancer activities moieties viz., antipyrine diazenyl benzaldehydes 2 (a-d) which were obtained by coupling of diazotized 4-aminoantipyrine (1) with substituted benzaldehydes at 0 • C (iced) temperatur...

Synthesis and study the liquid crystalline properties of new polymers containing substituted 1,3,4-oxadiazole ring

In this present study ten heterocyclic compounds were prepared from Azetidine (Two compounds) and Oxazepine (Eight compounds) and tested their ability to inhibit bacteria growth. The prepared compounds were tested for their antibacterial activity against Bacillussubtilis, Staphylococcusaureus (Grampositive) Pseudomonasaeruginosa,Escherichiacoli, an...

Solvent-free thermal heating, one-pot condensation of acetophenone, ethyl cyanoacetate or malononitrle and substituted Aromatic aldehyde, ammonium acetate give, 2-oxo-3-cyano-4-substituted Aryl-6-phenyl pyridine [I]a-h , or 2-amino-3-cyano-4-substituted Aryl-6-phenyl pyridine derivatives[II]a-f , respectively. Treatment of compounds 2-oxo-3-cyano-4...

The chalcones 1(a,b) were prepared by the reaction of 2-acetyl benzofuran with two aromatic aldehydes in the presence of alkaline media. These chalcones are used as starting material to obtain the desired heterocyclic: pyrazolin, isoxazoline, pyrimidinthion, pyrimidinone, cyclohexanone and indazole derivatives. The structure of newly synthesized he...

New Schiff bases derivatives [IV] a-e is prepared via condensation of D-erythroascorbic acid with p-substituted aldehydes in dry benzene. To obtain these derivatives, the 5,6-O-isopropylidene-L-ascorbic acid[I] was chosen as starting material, compound prepared from the reaction of L-ascorbic acid as starting material. Compound[I] was prepared from...

This work involves synthesis of novel Schiff bases derivatives contining isoxazoline or pyrazoline units starting with chalcons . 4-Aminoacetophenone was reacted with 3-nitrobenzaldehyde in basic medium giving chalcone [I] by claisen-schemidt reaction. The chalcone [I] was reacted with hydroxylamine hydrochloride giving isoxazoline [II] in basic me...

New twin compounds having four-, five-, and seven- membered heterocyclic rings were synthesized via Schiff bases (1a,b) which were obtained by the condensation of o-tolidine with two moles of 4-N,N-dimethyl benzaldehyde or 4- chloro benzaldehyde. The reaction of these Schiff bases with two moles of phenyl isothiocyanate, phenyl isocyanate or naphth...

A new series of heterocyclic compounds including four and five member rings have been synthesized. The new schiff bases derived from D-erythroascorbic acid were synthesized by condensation of D-erythroascorbic acid with aromatic amine (containing 1,3,4-oxadiazole or 1,3,4-thiadiazole unit) in dry benzene using glacial acetic acid as a catalyst. The...

The new schiff bases derived from D-erythroascorbic acid contaning heterocyclic unit were synthesized by condensation of D-erythroascorbic acid with aromatic amine (containing 1,3,4-oxadiazole or 1,3,4-thiadiazole unit) in dry benzene using glacial acetic acid as a catalyst. D-erythroascorbic acid [IV] was synthesized by four steps (Scheme 1), whil...

The new C-5 schiff bases derived from D-erythroascorbic acid contaning pyrimidine unit were sy nthesized by condensation of D-erythroascorbic acid with aromatic amine (containing pyrimidine unit)in dry benzene using glacial acetic acid as a catalyst. D-erythroascorbic acid was sy nthesized by four steps(Schem 1), while the aromatic amine which is c...

condensation of, glucosamine with substituted benzaldehydes in methanol under reflex afforded the new Schiff-bases; 2- (substituted benzylidene) amino-2-deoxy-D- glucose in good yields. some Schiff-base derivatives of glucose containing acetylenic bond were also prepared. hydroxy benzaldehydes were first converted to O-prop-2-ynyl- benzaldehydes fo...