Muhammad Saleem

Muhammad Saleem
University of Engineering and Technology, Taxila | UET Taxila · Department of Mechanical Engineering

About

49
Publications
27,404
Reads
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1,459
Citations
Citations since 2017
25 Research Items
1249 Citations
20172018201920202021202220230100200300
20172018201920202021202220230100200300
20172018201920202021202220230100200300
20172018201920202021202220230100200300

Publications

Publications (49)
Article
Objectives Polygnum hydropiper L (Polygonaceae) is commonly known as smart weed. This study was designed to assess the effect of aqueous methanolic extract of P. hydropiper on oxidative stress and metabolic changes in fructose-induced hypertensive rats. Methods Male Sprague-Dawely rats were divided into six groups of five animals each (n = 5) and...
Research
Full-text available
Natural Plants are broadly used in treating inflammatory disorders. The current study focused on evaluating the hepato-protective and anti-inflammatory potential of A. modesta in MnCL 2 induced hepatotoxicity and liver inflammation. The MnCl2 induce 6.0mg/kg was given for 30 days (p.o) to induced hepatotoxicity and liver inflammation. The ethanolic...
Article
Full-text available
Prazosin, a selective α1 adrenergic receptor antagonist, with documented anti-inflammatory potential, was evaluated for its antiarthritic efficacy by targeting specifically TNF-α. The antiarthritic attribute of prazosin validated through in vitro screening comprised thermally provoked denaturation of bovine serum albumin (BSA) and egg albumin along...
Article
Natural Plants are broadly used in treating inflammatory disorders. The current study focused on evaluating the hepato-protective and anti-inflammatory potential of A. modesta in MnCL2 induced hepatotoxicity and liver inflammation. The MnCl2 induce 6.0mg/kg was given for 30 days (p.o) to induced hepatotoxicity and liver inflammation. The ethanolic...
Article
Full-text available
Cancer has been a fatal disease since many decades. Over the time, it is presented in multiple ways and is a matter of consideration as accounts for the high rate of mortality. The aim of the current review was to focus on the genetics, epigenetics factors and role of medicinal plants for the cure of this inimical disease.. The genetic machinery is...
Article
Purpose: Matrix metalloproteinases, zinc dependent proteolytic enzymes, have significant implications in extracellular matrix degradation associated with tissue damage in inflammation and Rheumatoid arthritis. Numerous orchestrated pathways affects instigation and blockade of metalloproteinases as well as various factors that increase the expres...
Article
Purpose: Matrix metalloproteinases, zinc dependent proteolytic enzymes, have significant implications in extracellular matrix degradation associated with tissue damage in inflammation and Rheumatoid arthritis. Numerous orchestrated pathways affects instigation and blockade of metalloproteinases as well as various factors that increase the expressi...
Article
Full-text available
Cancer is a major health concern and one of the leading causes of death around the globe. Medicinal plants contain numerous phytochemicals and their usefulness for the treatment of cancer has been proven scientifically. The current review is aimed to provide a comprehensive knowledge about the herbal plants with established anti-cancer activity. Fo...
Article
Full-text available
Cancer is a major health concern and one of the leading causes of death around the globe. Medicinal plants contain numerous phytochemicals and their usefulness for the treatment of cancer has been proven scientifically. The current review is aimed to provide a comprehensive knowledge about the herbal plants with established anti-cancer activity. Fo...
Article
Full-text available
Cancer is a major health concern and one of the leading causes of death around the globe. Medicinal plants contain numerous phytochemicals and their usefulness for the treatment of cancer has been proven scientifically. The current review is aimed to provide a comprehensive knowledge about the herbal plants with established anti-cancer activity. Fo...
Article
Full-text available
Cancer is a major health concern and one of the leading causes of death around the globe. Medicinal plants contain numerous phytochemicals and their usefulness for the treatment of cancer has been proven scientifically. The current review is aimed to provide a comprehensive knowledge about the herbal plants with established anti-cancer activity. Fo...
Article
Ethnopharmacological relevance: Ribes alpestre Decne has been commonly used in the treatment of joint complaints. Aim of study: The present study was undertaken to evaluate the antiarthritic potential of ethanolic extract and fractions of Ribes alpestre and to explore its probable mechanism of action. Material and methods: Complete Freunds adjuvant...
Article
The building industry has a high energy consumption, which results in natural resource depletion, land use, ecosystem degradation, atmospheric pollution, and many other environmental impacts. Therefore, in modern construction, while maintaining a satisfactory and comfortable interior environment, less energy consumption and resource use is a major...
Article
The liver as a vital body organ is adversely affected by hazardous chemicals and drugs. Paracetamol widely used as analgesic and antipyretic drug produces severe hepatotoxicity at high doses. Present study was designed to investigate the hepatoprotective activity of Polygonum perfoliatum L. used on folklore basis. Aqueous methanolic extract of the...
Article
Full-text available
The liver as a vital body organ is adversely affected by hazardous chemicals and drugs. Paracetamol widely used as analgesic and antipyretic drug produces severe hepatotoxicity at high doses. Present study was designed to investigate the hepatoprotective activity of Polygonum perfoliatum L. used on folklore basis. Aqueous methanolic extract of the...
Article
Full-text available
Fundamental to this research was the evaluation of anticoagulant and thrombolytic potential of Berberis orthobotrys using clotting time, prothrombin time and activated partial thromboplastin time performed at 2.5, 5, 10% concentration. Aqueous-methanol extract significantly (p<0.05) increased the coagulation parameters both in human blood as well a...
Article
Full-text available
Finding a radical cure for diabetes has reached paramount importance in medicine due to the widespread prevalence of the disease. A substantial reduction in insulin-secreting beta cells is evident in diabetes. The failure of cyclin-dependent kinases (CDKs) and cyclins to access the nucleus is responsible for quiescence or senescence in human and ro...
Article
Full-text available
Context: Ficus carica L. (Moraceae) fruit is said to possess cardiovascular activity and has been used empirically in traditional phytotherapies for the treatment of hypertension and various other cardiovascular diseases. Objective: This study investigated the antihypertensive and cardioinhibitory activity of the aqueous-methanol extract of F. cari...
Article
Raman spectroscopy as a fast and nondestructive technique has been used to investigate heating effects on Desi ghee during frying/cooking of food for the first time. A temperature in the range of 140-180 C has been investigated within which Desi ghee can be used safely for cooking/frying without much alteration of its natural molecular composition....
Article
Full-text available
We performed a rapid global assessment of the availability and robustness of conservation strategies for ecoregions. In some cases this involved assessment of large regions composed of multiple ecoregions. We found ecoregion and regional conservation strategies through internet searches, guided by Google Search Engine, Google Scholar, literature ci...
Article
Full-text available
We assess progress toward the protection of 50% of the terrestrial biosphere to address the species-extinction crisis and conserve a global ecological heritage for future generations. Using a map of Earth's 846 terrestrial ecoregions, we show that 98 ecoregions (12%) exceed Half Protected; 313 ecoregions (37%) fall short of Half Protected but have...
Article
Full-text available
Viral hepatitis, an inflammatory liver disease, is caused by various genotypes of hepatitis C viruses (HCV). Hepatitis C slowly sprouts into fibrosis, which progresses to cirrhosis. Over a prolonged period of time compensated cirrhosis can advance to decompensated cirrhosis culminating in hepatic failure and death. Conventional treatment of HCV inv...
Article
Full-text available
This study is intended to develop a screening method for female breast cancer (BRC) from whole blood using Raman spectroscopy. A multivariate partial least squares (PLS) regression model is developed which is based upon Raman spectra of BRC-positive and healthy participants. It yields coefficients of regression at the corresponding Raman shifts. Th...
Article
Full-text available
In the globally changing scenario of water crises, efficient use of water is needed. Bed planting is one of the approaches to increase water use efficiency and crop productivity. The objective of this research study was to investigate impact of irrigation levels (I2 = 2 Irrigations, I3 = 3 Irrigations, I4 = 4 Irrigations, and I5 = 5 Irrigations) an...
Research
Full-text available
In the globally changing scenario of water crises, efficient use of water is needed. Bed planting is one of the approaches to increase water use efficiency and crop productivity. The objective of this research study was to investigate impact of irrigation levels (I2 = 2 Irrigations, I3 = 3 Irrigations, I4 = 4 Irrigations, and I5 = 5 Irrigations) an...
Article
The subject of Juvenile Justice System Ordinance is not a new thought but in Pakistan it was a vague law until the Parliament passed Juvenile Justice System Ordinance 2000. As per reports of UN committees on Juvenile, Amnesty International, NGOs and other institutions, violations of Juvenile Rights are widely reported in Pakistan. It is interesting...
Research
Law of tort has a comprehensive history and the development of tort law in relation to corporations cannot be comprehended fully without examining the body of corporate torts. In recent times, arguments focus over veil-piercing and liability of directors and shareholders instead of the issue of liability of corporation. Eventually, in order to exam...
Article
Specific performance is traditionally regarded in the English Law as an exceptional remedy. The principles upon which the English Judges exercise the discretion, to grant specific performance are reasonably well-settled and depend upon a number of considerations, mostly practical nature, which are of very general application. As Lord Hoffmann gave...
Article
The first decade of 21 st century have a special significance in the legislative history of Pakistan and India. It's a decade which is known for the dawn of freedom of information laws in both countries. In 2002 Pakistan became the first country in sub-continent which adopted freedom of information laws. Thanks to judicial activism which laid the f...
Article
All over the world Consumers, being unaware and uneducated to their rights, are considered the vulnerable part of business transitions. In Pakistan some efforts are made to protect them by enacting direct and some otherwise relevant legislation. "Islamabad Consumer Protection Act, 1995", "Khyber Pakhtunkhwa Consumers Protection Act, 1997", "Khyber...
Article
Full-text available
A complete diallel mating system involving eight divergent parents was used to work out the inheritance basis of degree of indetermination and its related parameters like plant height at flowering and maturity in mungbean. Eight parents, viz. 562-1, 56-2, NM-95, NM-92, L.No.1, L. No.21, 6601 and E32-1 were selected from 55 genotypes on the basis of...
Article
Full-text available
High density molecular linkage map is a prerequisite to identify the quantitative traits loci. Construction of linkage maps, using mapping populations derived from two major subspecies: indica and japonica in rice, have been reported. However, limited work was conducted in indica subspecies. Present studies focused to construct a molecular map base...
Article
Cotton is an important cash crop of Pakistan which is severely suffered from a leaf curl disease called cotton leaf curl disease. Studies had shown that a number of begomoviruses collectively called cotton leaf curl viruses (CLCVs) are responsible for leaf curl disease. Some of the important viruses in this group are Cotton leaf curl Multan virus,...
Article
Full-text available
Twenty advanced lines/genotypes of wheat including two check varieties were sown under two different sowing times through out the Punjab province at 18 different locations with diverse environments to study their stability and adaptability. Normal sowing was done in second week of November 2007 while the delayed sowing was completed during second w...
Article
Full-text available
In transverse orientation, maize (Zea mays) roots are composed of a central stele that is embedded in multiple layers of cortical parenchyma. The stele functions in the transport of water, nutrients, and photosynthates, while the cortical parenchyma fulfills metabolic functions that are not very well characterized. To better understand the molecula...
Article
The different root types of maize (Zea mays L.) originate from distinct tissues during development. The maize mutant rum1 (rootless with undetectable meristems 1) does not initiate seminal roots and lateral roots in the primary root. While seminal roots are laid down during embryogenesis, endodermis cells of the parenchyma, and pericycle cells of t...
Article
Full-text available
Each plant cell type expresses a unique transcriptome and proteome at different stages of differentiation dependent on its developmental fate. This study compared gene expression and protein accumulation in cell-cycle-competent primary root pericycle cells of maize (Zea mays) prior to their first division and lateral root initiation. These are the...
Article
Full-text available
Plant development is controlled by complex endogenous genetic programs and responses to environmental cues. Proteome analyses have recently been introduced to plant biology to identify proteins instrumental in these developmental processes. To date most plant proteome studies have been employed to generate reference maps of the most abundant solubl...
Article
Full-text available
Attempts to improve mungbean have been mainly confined either to examination of varietal differences or selections from the cultivator's improved stocks. Cognizant of this situation, the Asian Regional Center of the Asian Vegetable Research and Development Center (ARC-AVRDC), Thailand and Nuclear Institute for Agriculture & Biology (NIAB), Pakistan...
Article
Full-text available
A renal allograft recipient was treated for genitourinary tuberculosis with reinstitution of Rifampicin after a medication free interval of 8 months, earlier he was treated for tubercular pleural effusion. After eight days of treatment patient developed severe hemolytic anemia and acute renal failure necessitating dialysis. Biopsy taken from graft...

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