About
140
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Introduction
Muhammad Riaz currently works at the Department of Pharmacy, Shaheed Benazir Bhutto University, Sheringal. Muhammad does research in Pharmacy. Their most recent publication is 'Ginseng: A dietary supplement as immune-modulator in various diseases'.
Additional affiliations
May 2014 - present
November 2012 - April 2014
Education
March 2016 - March 2017
May 2010 - December 2010
February 2008 - September 2012
Publications
Publications (140)
Objective: this study was conducted in order to evaluate the admissions due to comiogenesis that affect the patient quality of life. The identification of comiogenic admissions and their possible solutions to achieve the optimal therapeutic outcomes of the patients.
Material & Methods: In this study the 32 days concurrent prescriptions was evaluate...
The current study was designed to investigate the traditional recipes used to treat cough in Piran, Malakand, Pakistan. These recipes were explored and quantitatively analyzed for the first time. A total of 30 species of the plants, 6 animal products and one salt were reported to be used by the community to treat cough. Punica granatum L. and Olea...
Background
Solanum pseudocapsicum (PC) and Capsicum annum (CA) belongs to the family of Solanaceae. CA have been reported a rich source of phenolics whereas, the phenolics content of GA (gallic acid), SC (scopoletin), RA (rosmarinic acid), and RV (resveratrol) are yet to be reported for the PC-fruit. This study comparatively evaluates the phenolics...
The control of infections is one of the key strategies to treat cuts, wounds, lung, and skin infections. In this study the folkloric use of Rumex dentatus (R. dentatus) roots in the mentioned conditions was scientifically investigated. The methanolic (MeOH) crude extract of R. dentatus root was fractionated (n-hexane, ethyl acetate and water) via b...
Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimat...
Abstract The quality of olive fruit (OF) is widely affected due to geographical variation, affecting OF's chemical composition and biological properties. It is a novel and first-time study to evaluate the quality variation of 42 olive samples from different geographical origins based on phytochemical profile and their biological activities. The stu...
The Article Abstract is not available.
This study, for the first time, reports a simultaneous determination of flavonoids; rutin (RT), quercetin (QT), luteolin (LT), and kaempferol (KF) in different origins of fenugreek seeds samples (N = 45) using a green UHPLC-DAD analysis METHODOLOGY: Ultrasound-assisted extraction (UAE) was employed to extract fenugreek flavonoids using different po...
Mango fruit is well known for its nutritional and health benefits due to the presence of a plethora of phytochemical classes. The quality of mango fruit and its biological activities may change depending upon the variation in geographical factors. For the first time, this study comprehensively screened the biological activities of all four parts of...
Cancer is the leading cause of mortality and morbidity worldwide, and its cases are rapidly increasing every year. Several factors contribute to the development of tumorigenesis. including radiation, dietary lifestyle, smoking, environmental, and genetic factors. The cell cycle is regulated by a variety of molecular signaling proteins. However, whe...
This study conducted in order to evaluate the admissions due to comiogenesis that affect the patient quality of life. The identification of iatrogenic admissions and their possible solutions to achieve the optimal therapeutic effects of the patients.
Material & Methods: The total of 32 days study carried out in Endocrinology department, the total o...
Background
The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to bring...
Background:
Geographical variation may affect the phytochemistry as well as the biological activities of Glycyrrhiza glabra (licorice) root. Herein, a series of biological activities were performed to evaluate the impact of geographical origin on the biological potential of eight different licorice samples.
Methodology:
Cell culture studies were...
Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to brin...
The disastrous effects of COVID-19 on health, education, and economy prompt for the development of an effective vaccine candidate in order to this global issue. The vaccine candidature against COVID-19 depends on the virus spike (S) protein engrained with the property of pathogenicity. Previously, a number of vaccines have been developed utilizing...
This study through light on actual role of Clinical Pharmacists and their relationships with Physicians as well as challenges to Clinical Pharmacists in Pakistan. Pharmacy is a patient oriented profession and a Pharmacist should be clinically smart and strong, the relation between Physician and Pharmacist of many decades but unfortunately this area...
A curriculum is designed to meet the current challenges. To achieve the goal, this curriculum needs to be reviewed and evaluated regularly. The main aim of this study is to highlight concern with the PharmD program curriculum specifically the Clinical Pharmacy in Pakistan. The curriculum of PharmD, more specifically the subject Clinical Pharmacy wa...
Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to brin...
The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to bring together i...
Background:
Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades.
Methods:
Using the Global Burden of Disease, Injuries, and...
Diabetes mellitus is a metabolic disorder and is a global challenge to the current medicinal chemists and pharmacologists. This research has been designed to isolate and evaluate antidiabetic bioactives from Fragaria indica. The crude extracts, semi-purified and pure bioactives have been used in all in vitro assays. The in vitro α-glucosidase, α-am...
This study evaluates the quality variation for twenty-seven capsicum fruit (CF) samples, in terms of their volatile oil composition and biological activities. The GCMS analysis revealed the presence of seventy one chemical compounds from different chemical classes with an average (%) composition of: 26.13 (alcohols) > 18.82 (hydrocarbons) > 14.97 (...
Currently, the whole world is facing a life-threatening novel coronavirus 2019 (COVID-19) pandemic. Natural products are well-known for their potential role against viral disease, and some anti-viral agents have been developed to combat these diseases. Herein, the authors investigated the possible effects of this Holy plant Nigella sativaL. (NS), a...
Currently, the whole world is facing a life-threatening novel coronavirus 2019 (COVID-19) pandemic. Natural products are well-known for their potential role against viral disease, and some anti-viral agents have been developed to combat these diseases. Herein, the authors investigated the possible effects of this Holy plant Nigella sativa L. (NS),...
Medicinal plants are widely used in the Kingdom of Saudi Arabia to treat various ailments in the form of folk medicine. Forty four such medicinal plant samples were collected from local markets and evaluated for the presence of 14 elements (Mn, Cr, Co, Ni, Cu, Mo, Al, Pb, Ba, Zn, Ag, Hg, Bi, Cd). Microwave-assisted digestion with inductively couple...
The journal of APJCP (Asian Pacific Journal of Cancer Prevention) focuses to gather relevant and up-to-date
novel information’s related to cancer sciences. The research methodologies and approaches adopted by the researcher
are prone to variation which may be desirable in the context of novel scientific findings however, the reproducibility
for the...
Introduction: This study conducted in order to evaluate the admissions due to comiogenesis that affect the patient quality of life. The identification of iatrogenic admissions and their possible solutions to achieve the optimal therapeutic effects of the patients.
Material & Methods: The total of 32 days study carried out in Endocrinology departme...
Himalaiella heteromalla (D.Don) Raab-Straube is a commonly used remedy against various diseases. Crude extract and fractions of H. heteromalla were investigated for a gastrointestinal, bronchodilator, cardiovascular, and anti-inflammatory activities. H. heteromalla crude extract (Hh.Cr) relaxed spontaneous contractions and K+ (80 mM)-induced contra...
Introduction: The administration errors are the predominant subpart of medication errors that is the third leading cause of deaths in the United States. It has been documented by World Health Organization (WHO) that most health team members are untrained about safe injection administration practices and, therefore, liable to error. The current stud...
This review present Gingko biloba (GB) interactions, based on clinical and pre-clinical presentations. Literature was retrieved using databases; ScienceDirect, PubMed, Google scholar, Web of Science, Scopus etc. 14/45 interactions were found with clinical presentations. More interactions (80%) were reported with drugs followed by herbs (11.1%), and...
Background: Local people of the Kumrat Valley, district Upper Dir in Northwest Khyber Pakhtunkhwa, Pakistan rely on wild food plants (WFP) for nutrition, medicine, and monetary value. The present study aimed to accomplish a detailed investigation of local wild food plants and their therapeutic importance to identify innovative organic food products...
Reishi owes an exceptional value in nutritional, cosmeceutical, and medical treatments; however, none of the studies has provided its future‐driven critical assessment. This study documents an up‐to‐date review (2015–2020, wherever applicable) and provide valuable insights (preclinical and clinical evidence‐based) with comprehensive and critical as...
The current study was designed to investigate the traditional recipes used to treat cough in Tehsil Piran, Malakand, Pakistan. These recipes were explored and quantitively analyzed for the first time. A total of 30 species of the plants, 6 animal products and one salt were reported to be used by the community to treat cough. Punica granatum L. and...
The current study was designed to investigate the traditional recipes used to treat cough in Tehsil Piran, Malakand, Pakistan. These recipes were explored and quantitively analyzed for the first time. A total of 30 species of the plants, 6 animal products and one salt were reported to be used by the community to treat cough. Punica granatum L. and...
Trianthema triquetra Rottler & Willd (Tt.Cr) is used in traditional practices as a remedy for various ailments. Hence current research was commenced to authenticate the folkloric uses. To discover spasmolytic potential, Tt.Cr was applied to isolate jejunum, while isolated tracheal and aorta tissues were used to determine the tissue relaxing propert...
As per latest updates on the vaccines by the World Health Organization (WHO), the total number of vaccines currently under development is more than 192. About 151 are presently investigated in the preclinical phases, while 42 of these vaccine candidates are in the various phases of clinical trials. Ten of these are in the advanced stages of clinica...
Carotenoids are natural products having a broad spectrum of biological applications, such as, anti-cancer, anti-oxidants, anti-inflammatory and anti-ageing etc. Chemically, they contain long chains of carbon atoms having conjugation and these conjugated systems enable them to act as radical scavengers. Therefore, they have potential applications in...
The number of Carotenoids of most natural sources is not as much of, so frequent dosing and a large amount of the source need to be consumed. The fortified carotenoid source overcomes this problem. Several strategies are used to fortify carotenoid content. One is the agricultural conventional breeding method, while the second includes the genetic e...
Apocarotenoids are organic compounds which are derived from carotenoids by oxidative cleavage, catalyzed by carotenoid oxygenases i.e. abscisic acid, retinol, retinoids, retinal and retinoic acid. They have significant role in nutrition as a source of vitamin A, and lend protection against chronic diseases such as, arthritis, cardiovascular disorde...
Ingestion of calorie-rich foods, sedentary life-style counpled with energy disparity is leading towards obesity and related complications in humans. Many preclinical and clinical studies confirm anti-obesity properties of functional foods lie carotenoids. This chapter highlights recent information on the importance of carotenoids and its various me...
Carotenoids are symmetrical tetraprenoid units consisting of highly unsaturated liner C40 hydrocarbon chains as key structural element. Epidemiological studies suggest a direct relationship with higher ingestion of carotenoids containing foods and reduced chances of osteoporosis. Bone remodeling is continuous process controlled by osteoclasts and o...
Parkinson’s disease (PD) is a neurodegenerative disease associated with the loss of dopaminergic neurons in the portions of the brain via multiple pathological mechanisms. Despite the fact that enormous progress occurred in the cure of Parkinson’s disorder, but the incidence and risk of this disease is increasing alarmingly over the past few decade...
Carotenoids are the second most abundant natural compounds after chlorophyll. Chemically they are made of 8 isoprene units (typically tetra-terpenoids) joined in head to tail arrangement. They have several trivial names and still known by these names; however, their proper IUPAC naming initiated in the ’70s. Carotenoids are classified into various...
Carotenoids are non-nitrogenous molecules, which possess a basic linear, symmetrical skeleton of 40-carbon tetraterpene assembled from eight 5-carbon isoprenoid units joined such that the order is reversed at the center. They are present in an extensive array of natural milieus, such as in the plant kingdom, oceans, glaciers, hot springs, and salt...
Carotenoids are prenol lipids and make up the cluster of C40 isoprenoids. Being ubiquitous plant metabolites, they are integral part of human diet. Carotenoids have extended polyene chromophores and can have hexyl-rings on ends. The range of chemical structures are due to modifications in their core skeleton, shifting of c.d.b. and attachment of va...
Carotenoid had been known for a longer period of time but in 1960’s its synthesis and metabolic products were elucidated. Carotenoids are lipophilic in nature so require the same pathway as lipids for digestion, absorption and circulation in the blood. Carotenoids may be provitamin A or others as lycopene and xanthophyll, which have no function as...
A curriculum is designed to meet the current
challenges. To achieve the goal, this curriculum
needs to be reviewed and evaluated regularly.
The main aim of this stydy is to highlight concern
with the PharmD program curriculum,specifically
the Clinical Pharmacy in Pakistan.
The curriculum of PharmD, more specifically
the subject Clinical Pharmacy wa...
A range of conventional i.e. maceration (ME), percolation (PE), ultrasonic assisted (USE), soxhlet (SLE) and soxtec extraction (STE) to an advanced extraction technique of accelerated solvent extraction (ASE) was utilized for the first time in order to optimize extract yield and recovery of phenolics; gallic acid (GA), rutin (RT) and quercetin (QT)...
Pistacia chinensis subsp. integerrima (J. L. Stewart ex Brandis) Rech. F. is a valuable medicinal plant used in south Asian communities for the treatment of asthma, diarrhea, diabetes, liver diseases, fever, pain and inflammation. This review critically evaluates the available information on P. integerrima’s ethnobotany, ethnopharmacology, phytoche...
Background:
It is essential to follow World Health Organization drug prescribing indicators to ensure rational prescribing in every health care setting.
Objective:
To evaluate the prescriptions in the endocrinology department, according to the World Health Organization (WHO), recommended Ghana guidelines for diabetes management and rational ther...
Background. It is essential to follow World Health Organization drug prescribing indicators to ensure rational prescribing in every health care setting. Objective. To evaluate the prescriptions in the endocrinology department, according to the World Health Organization (WHO), recommended Ghana guidelines for diabetes management and rational therapy...
Current study was designed to investigate the in vivo analgesic and anti-inflammatory potential of extracts of aerial and underground parts of Acacia modesta in mice and rat animal models. Formalin-induced inflammation and carrageenan-induced inflammation models were used for the assessment of anti-inflammatory activity.
In this piece of study one case evaluated relevant to the dose calculation in which six formulas utilized for calculation of optimal doses and comparison between these formulas as well as beauty of all formulas. The different formulas used like on the basis of age includes Young rules, Dilling rules, Bastedo rules, Crowling, on the basis of weight...
Background: Rational drugs are safe, effective and medico-socio-economical for the patients. The rational use of drugs
Tagetespatula L. is a widely cultivated herbal medicinal plant in China and other countries. In this study, two new 2, 3-dihydrobenzofuran glucosides (1, 2) and fourteen known metabolites (3-16) were isolated from the stems and leaves of T. patula (SLT). The chemical structures of the isolated compounds were characterized comprehensively based on o...
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the level of DHT, reducing the secretion of PSA and TNF-α. Besides,...
Evaluation of smooth muscle relaxant potential of Bismarckia nobilis (Hildebr. & Wendl.) in diarrhea, hypertension and asthma by ex-vivo and in-vivo method [Evaluación del potencial relajante en músculo liso de Bismarckia nobilis (Hildebr. & Wendl.) en diarrea, hipertensión y asma por métodos ex vivo e in vivo] Abstract: To explore the mechanistic...
Background: Mechanistic studies suggest that ginseng, as dietary supplement, plays a key role in disease prevention by modulating the immune function of human body. The root of Panax ginseng and Panax quinquefolius (Family: Araliaceae) are commonly known as ‘ginseng’. Ginseng roots are well known for their high content of saponins, ginsenosides, ph...
Multidrug resistance (MDR) is regarded as one of the bottlenecks of successful clinical treatment for numerous chemotherapeutic agents. Multiple key regulators are alleged to be responsible for MDR and making the treatment regimens ineffective. In this review, we discuss MDR in relation to P-glycoprotein (P-gp) and its down-regulation by natural bi...
The current study has been designed to appraise the antioxidant, antimicrobial and hae-molytic potential of Smilax macrophylla leaves. The n-hexane fraction was analysed by Gas Chro-matography/Mass Spectrometer which revealed the presence of 38 compounds. All examined extracts and fractions of plant leaves showed significant antimicrobial activity....
The popularity in utilization of the plant-based remedies has increased worldwide over the last 30 years. One of the main reasons for this increased popularity is probably the belief that natural product-based diet and herbal-based preparations have been used for centuries and that natural products are safe. In parallel with the revival of interest...
Anthocyanins are secondary plant metabolites and are chemically di- or tri-hydroxy B-ring-substituted flavonoids containing a flavylium cation. These are focus of much attention these days due to their vibrant colors and immunity-boosting and health-promoting effects mainly in ameloriating various cholesterol-related and oxidation-induced diseases....
Anthocyanins are the largest group of water-soluble pigments of plant kingdom, are odorless and flavorless and occur in various parts of plants, nuts, vegetables, fruits, legumes and cereals where they perform various specific functions. All anthocyanins are made up of a common single aromatic structure, i.e. cyanidin with different modifications a...