Muhammad-Redha Abdullah-Zawawi

Muhammad-Redha Abdullah-Zawawi
Universiti Kebangsaan Malaysia | ukm · UKM Medical Molecular Biology Institute (UMBI)

Doctor of Philosophy (Systems Biology)

About

17
Publications
3,975
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
110
Citations
Citations since 2017
15 Research Items
109 Citations
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060

Publications

Publications (17)
Article
Aliphatic glucosinolate is an important secondary metabolite responsible in plant defense mechanism and carcinogenic activity. It plays a crucial role in plant adaptation towards changes in the environment such as salinity and drought. However, in many plant genomes, there are thousands of genes encoding proteins still with putative functions and i...
Article
Full-text available
Plants produce a wide range of secondary metabolites that play important roles in plant defense and immunity, their interaction with the environment and symbiotic associations. Sulfur-containing compounds (SCCs) are a group of important secondary metabolites produced in members of the Brassicales order. SCCs constitute various groups of phytochemic...
Article
Glucosinolates (GSLs) are plant secondary metabolites comprising sulfur and nitrogen. These compounds are mainly found in plants from the order of Brassicales, such as broccoli, cabbage, and Arabidopsis thaliana. The activated forms of GSL play important roles in fighting against pathogens and have health benefits to humans. The increasing amount o...
Article
Ecdysone receptor (EcR) is the primary regulator of the ecdysteroid signalling pathway, a critical pathway that directly links to moulting. In addition, EcR also regulates growth, development, reproduction and regeneration in crustaceans. However, there remains a huge gap of knowledge between the detailed structure and functional role(s) of crustac...
Article
Full-text available
Transcription factors (TFs) form the major class of regulatory genes and play key roles in multiple plant stress responses. In most eukaryotic plants, transcription factor (TF) families (WRKY, MADS-box and MYB) activate unique cellular-level abiotic and biotic stress-responsive strategies, which are considered as key determinants for defense and de...
Article
Nitrate transporter (NRT) is responsible for the molecular mechanism of the root nitrate (NO3-) uptake system for plant development. Although several NRT genes are identified and characterised in plants, knowledge of the NRT2 gene family and its nitrogen use efficiency (NUE) function in drought stress has remained elusive in rice. This study conduc...
Article
Full-text available
Background Phytochemicals or secondary metabolites are low molecular weight organic compounds with little function in plant growth and development. Nevertheless, the metabolite diversity govern not only the phenetics of an organism but may also inform the evolutionary pattern and adaptation of green plants to the changing environment. Plant chemoin...
Article
Full-text available
In higher plants, the complexity of a system and the components within and among species are rapidly dissected by omics technologies. Multi-omics datasets are integrated to infer and enable a comprehensive understanding of the life processes of organisms of interest. Further, growing open-source datasets coupled with the emergence of high-performan...
Article
Full-text available
Auxin receptor plays a significant role in the plant auxin signalling pathway in response to abiotic stress. Recently, we found that transgenic rice overexpressing ABP57 had higher drought tolerance than the wild-type cultivar, MR219, due to the fact of its enhanced leaf photosynthetic rate and yields under drought stress. We performed a microarray...
Article
Full-text available
Abstract Sulfur is an essential element required for plant growth and development, physiological processes and stress responses. Sulfur-encoding biosynthetic genes are involved in the primary sulfur assimilation pathway, regulating various mechanisms at the gene, cellular and system levels, and in the biosynthesis of sulfur-containing compounds (SC...
Article
Full-text available
Soil salinity is one of the most serious environmental challenges, posing a growing threat to agriculture across the world. Soil salinity has a significant impact on rice growth, development, and production. Hence, improving rice varieties’ resistance to salt stress is a viable solution for meeting global food demand. Adaptation to salt stress is a...
Article
Full-text available
Protein–protein interaction (PPI) is involved in every biological process that occurs within an organism. The understanding of PPI is essential for deciphering the cellular behaviours in a particular organism. The experimental data from PPI methods have been used in constructing the PPI network. PPI network has been widely applied in biomedical res...
Article
Full-text available
The inhibition of dipeptidyl peptidase-IV (DPPIV) is a popular route for the treatment of type-2 diabetes. Commercially available gliptin-based drugs such as sitagliptin, anagliptin, linagliptin, saxagliptin, and alogliptin were specifically developed as DPPIV inhibitors for diabetic patients. The use of Gynura bicolor in treating diabetes had been...
Data
Structural alignment, pockets, glycosylation and active sites analysis of 3WQH, 3W2T, 4A5S, 4FFW, 4PNZ and 4PV7 receptors. Supplementary Figure 1: mulPBA alignment of crystal structure similarities for 3WQH, 3W2T, 4A5S, 4FFW, 4PNZ and 4PV7 receptors. Supplementary Figure 2: Analysis result on 3WQH, 3W2T, 4A5S, 4FFW, 4PNZ and 4PV7 receptors crystal...
Article
Full-text available
Inhibition of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) has been a useful strategy in the treatment of cardiovascular disease. Molecular docking study was carried out to study the effects of geraniin and its metabolites on 3-hydroxy-3-methyl-glutaryl-CoA reductase. 3-hydroxy-3-methyl-glutaryl-CoA reductase acts on melavonate pathway for chol...

Network

Cited By