Objective: To evaluate the antioxidant potential and pancreatic lipase inhibitory action of optimized hydroethanolic extracts of Solanum nigrum. Methods: Optimized extraction for maximum recovery of metabolites was performed using a combination of freeze-drying and ultrasonication followed by determination of antioxidant and antiobesity properties....

Extract yield (%) of different extracts from C. fistula leaves. Values...

The DPPH radical scavenging activity of different extracts from C....

Inhibitory activities of different extracts of C. fistula towards PL....

UHPLC chromatogram of 80% ethanolic extract of C. fistula leaf.

Possible fragmentation patterns of identified compounds.

Cassia fistula Leaves; UHPLC-QTOF-MS/MS Based Metabolite Profiling and Molecular Docking Insights to Explore Bioactives Role towards Inhibition of Pancreatic Lipase

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Jun 2021

The present work was aimed at investigating hydroethanolic leaf extracts of Cassia fistula for their antioxidant and pancreatic lipase (PL) enzyme inhibitory properties. The most active extract was selected to profile the phytoconstituents by UHPLC-QTOF-MS/MS technique. Among the tested extracts, the 80% hydroethanolic extract exhibited the maximum...

Ultrasonication-assisted extraction, antioxidant activity and α-amylase inhibition potential of vitex negundo leaves

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May 2020

The current work describes the ultrasonicated assisted extraction followed by comprehensive investigation of antioxidant activity and α-amylase inhibition potential of hydroethanolic leaf extracts of Vitex negundo. Freeze drying assisted ultrasonicated extraction revealed highest level of total phenolic contents (258.29±2.52 mgGAE/g DE) and total f...

Antidiabetic functionality of Vitex negundo L. leaves based on UHPLC-QTOF- MS/MS based bioactives profiling and molecular docking insights

Article

May 2020

Diabetes is one of the leading causes of death in the world which can be effectively managed by consuming functional foods consisting of medicinal plants. Vitex negundo L. is one of the extensively used plants against wide spectrum of diseases in traditional medicinal systems. Therefore present study was undertaken to explore the bioactive profilin...

0123456789) 1 3 Journal of Food Measurement and Characterization

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May 2020

Figure 1. Extraction yield (%) of different hydro-ethanolic extracts.

Figure 2. DPPH scavenging potential of extracts of different...

Figure 3. Total antioxidant power assay to assess anti-oxidant activity.

Figure 4. Comparative percentage inhibition for β-Carotene bleaching by...

Figure 5. In-vitro α-amylase inhibitory potential of B. monosperma...

UHPLC-QTOF-MS/MS based phytochemical characterization and anti-hyperglycemic prospective of hydro-ethanolic leaf extract of Butea monosperma

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Feb 2020

Butea monosperma is one of the extensively used plants in traditional system of medicines for many therapeutic purposes. In this study, the antioxidant activity, α-glucosidase and α-amylase inhibition properties of freeze drying assisted ultrasonicated leaf extracts (hydro-ethanolic) of B. monosperma have been investigated. The findings revealed th...

UHPLC-QTOF-MS/MS chromatogram of 80% HE C. reflexa extract.

Structures and MS/MS spectra of compounds (1–13) identified in 80% C....

Proposed fragmentation pattern of compounds identified from C. reflexa...

(a). Ribbon diagram for α-glucosidase (homology modeled). The 3 AARs...

(a–d). The 3-D interaction plot of identified phytochemicals (1–4) into...

UHPLC-QTOF-MS/MS metabolites profiling and antioxidant/antidiabetic attributes of Cuscuta reflexa grown on Casearia tomentosa: exploring phytochemicals role via molecular docking

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Jan 2020

Present study reports metabolites profiling, antioxidant, and antidiabetic effects of Cuscuta reflexa grown on Casearia tomentosa. The UHPLC-QTOF-MS/MS method was used to characterize phytochemicals in most potent extract. Thirteen bioactive compounds/metabolites including (2S)-3-(β-D-galactopyranosyloxy)-2-(hexanoyloxy)propyl nonanoate, 4-O-β-D-gl...