Mudiganti Ram Krishna Rao

• B.Sc.(Hons), M.Sc. (Zoology), Ph.D.(Genetics)
• Professor (Full) at Bharath University

The present article is the 3rd in the series of Nootropic Plants: A Review. In this article the nootropic role of 7 plants is discussed. The data was collected from various published sources and compiled.

Medhya Rasayanas are group of medicinal plants described in Ayurveda (Indian system of medicine) with multi-fold benefits, specifically to improve memory and intellect by Prabhava (specific action). Medha means intellect and/or retention and Rasayana means therapeutic procedure or preparation that on regular practice will boost nourishment, health,...

Amritotharanam Kashyam, a specific Ayurvedic drug, was the focus of the current inquiry to evaluate its efficacy. For liver and digestive-related issues, this medication is suggested. This was obtained from a standard Ayurvedic vendor in Chennai (India), and GC-MS analysis was carried out according to the standard procedure. A few critical biomolec...

Background The present study deals with the GC MS analysis of one Ayurvedic medicine, Kushmanda Rasayanam. Kushmanda rasayanam is a medicine prescribed to treat cough, breathing problems, chest injuries, bleeding disorders and depletive diseases. It is also claimed that its use increases memory power, intellect and is a good heart tonic. Results Th...

This works embarks upon the gas chromatography mass spectroscopic analysis of one Unani drug, “Majoon falasifa” which is prescribed for ailments of nerves, digestive and reproductive systems. The drug was bought from a Unani medicine supplier and was processed suitably to be analysed by GC MS process. The compounds namely, Butanoic acid, 2-methyl-,...

The present work is to analyse one Ayurvedic formulation, Rasnadichurnam by GC MS to know the types of molecules present in it. The medicine was procured from a standard Ayurvedic vendor at Chennai, India and was subjected to Gas Cnromatography Mass Spectroscopic analysis after processing it as per standard protocol. The molecules indicated by the...

The Gas Chromatography Mass Spectroscopic study Ayurvedicformulation, Panchagandhachurnam was performed in the present report.The formulation was subjected to Gas Chromatography Mass Spectroscopicanalysis after processing it as per standard protocol.The Gas Chromatography Mass Spectroscopicstudy of Panchagandhachurnamdepicted some bio-molecules, su...

The present study deals with the anti-oxidant test of Ayurvedic medicine Madhukasavam. Madhukasavam is a polyherbal Ayurvedic medicine useful in treating grahni (malabsorption syndrome), skin diseases, and wasting syndrome. The present study was to understand the antioxidant capacity of this medicine and the study consisted of four types of antiox...

The present study deals with the GC MS analysis of one Ayurvedic formulation, Pathadi chrunam. The medicine was procured from standard Ayurvedic vendor at Chennai, India and was suitably processed before subjecting it to GC MS analysis. Some important molecules such as Methyl 4,7,10,13-hexadecatetraenoate, Z,E-2,13-Octadecadien-1-ol, trans-2-methyl...

Objective: The present study deals with the GC MS analysis of one Ayurvedic medicine, Avalgujabijadi chrunam, which is prescribed for skin diseases such as Vitiligo, Tinea infection and burns. The main constituent of this medicine is Avalgujabija, i.e. Psoralea corylifolia seeds, which is a proven medicine for skin diseases. Methods: The medicine,...

Objective: The present study embarks upon the GC MS analysis of one Ayurvedic formulation, Kachuradi churnam prescribed for treating headache, dizziness, sleeplessness and stress. Methods: The medicine was procured from standard Ayurvedic vendor at Chennai and was processed as per standard protocol and subjected to GC MS analysis. Results: The GC M...

Objective: The present study is to subject one Ayurvedic formulation Dadimashtaka churnam to GC MS analysis to find the types of molecules present therein. This medicine is prescribed for digestive disorders like malabsorption syndrome, irritable Bowel syndrome, diarrhoea, lack of appetite etc. Methods: The medicine was procured form standard Ayurv...

This is an Open Access Journal / article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 3.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. All rights reserved. The present study deals with the GC MS analysis of one Ayurvedic medicine...

This is an Open Access Journal / article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 3.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. All rights reserved. The present study embarks upon the GC MS analysis of one Ayurvedic medicin...

Objective: The present work deals with the GC MS analysis of one Ayurvedic medicine, Chanadansavam, which is prescribed for the treatment of various kidney and urinary ailments. Methods: The medicine, Chanadanasavam was procured from standard Ayurvedic vendor at Chennai and was subjected to GC MS analysis after processing as per standard protocol....

This is an Open Access Journal / article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 3.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. All rights reserved. The present study deals with the GC MS analysis of one Ayurvedic medicine...

Balarishtam is an Ayurvedic nerve tonic. The present study deals with the GC MS analysis of the medicine to understand the biomolecules present and their possible nerve related activity. Balarishtam was subjected to GC MS analysis. The presence of some important molecules such as Eucalyptol, 2-Isopropoxyethylamine, p-menth-1-en-8-ol, Eugenol, N-Ace...

Balarishtam is an Ayurvedic nerve tonic. The present study deals with the GC MS analysis of the medicine to understand the biomolecules present and their possible nerve related activity. Balarishtam was subjected to GC MS analysis. The presence of some important molecules such as Eucalyptol, 2-Isopropoxyethylamine, p-menth-1-en-8-ol, Eugenol, N-Ace...

The lipid pattern and levels in diabetic patient are the same as those for subjects with cardiovascular disease. The tactic underlying the oral hypoglycemic agent is to adjust the lipid profile; which can be achieved by herbal therapy. The use of herbs and formulations for attenuation of hyperglycemia and to aid protection against the pancreatic da...

Many plants provide a rich source of bioactive chemicals, which are free from undesirable side effects and possess powerful pharmacological actions. The present study was carried out to find the antidiabetic effect of Katakakhadiradi kashayam (KKK) by improving the insulin expression and regulating properly the glucose metabolising enzymes. The dia...

Plants have the ability to impart therapeutic action on chronic diseases such as diabetes and its comorbidities. The current study was done to find the effectiveness of Katakakhadiradi kashayam on liver metabolism in streptozotocin and nicotinamide administered diabetic rats. Diabetic rats were treated with katakakhadiradi kashayam for 28 days and...

The present study deals with the GC MS analysis of one Ayurvedic medicine, Nasika Churna which is used for the treatment of respiratory diseases. Nasika churnam was procured from a standard Ayurvedic vendor at Chennai and subjected to GC MS analysis following standard protocol. Some important molecules such as Cyclobutane-1,1-dicarboxamide, N,N'-di...

The present study deals with the GC MS analysis of one Ayurvedic emedicine, Sitopaladi, which is prescribed for the treatment of respiratory diseases. Sitopaldai was purchased for standard Ayurvedic vendor at Chennai and subjected to GC MS analysis following standard protocol. Some biomolecules of medicinal importance such as Clindamycin, d-Glycero...

The article indicates the effectiveness of one cardiotonic ayurvedic medicine Partharishtam on animal model.

Objective: There is an urgent need to prove the authenticity of Ayurvedic medicines in the light of modern scientific knowledge. Methods: The present study deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one herbal oil, Kunthalakanti Thailam, to understand the molecules present there in. Kunthalakanti Thailam was bought from...

Objective: The present study deals with the gas chromatography-mass spectrometry (GC- MS) analysis of one digestive Ayurvedic formulation, Induppukanam. Materials and Methods: Induppukanam was procured form a standard Ayurvedic vendor at Chennai and was subjected to GC-MS analysis following standard procedure. Results: Some important molecules such...

Objective: The aim of the present study is to known about the types of molecules present in one Ayurvedic medicine, Srikhandasavam prescribed for alcohol de-addiction and liver protection, by gas chromatography-mass spectrometry (GC MS) analysis. Materials and Methods: Srikhandasavam was procured from standard Ayurvedic vendor at Chennai and subjec...

Objective: The present study deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one Ayurvedic formulation, Tiktaka Ghrita, which is prescribed for skin diseases. Materials and Methods: The medicine was procured from standard Ayurvedic vendor at Chennai and was subjected to GC-MS analysis after due processing. Results: It was ob...

Objective: The present study deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one Ayurvedic tooth powder Dasanakanti Churnam to understand the various molecules present in it. Materials and Methods: The medicine, Dasanakanti Churnam, was procured from a standard Ayurvedic vendor at Chennai and was subjected to GC-MS analysis...

Introduction: The present study deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one Ayurvedic digestive powder, Trikatu Churnam. Materials and Methods: The Trikatu Churnam was procured for standard Ayurvedic vendor at Chennai and was subjected to GC-MS analysis by the standard as per the standard procedure. Results: The GC-M...

Objective: The present study deals with the GC-MS analysis of one Ayurvedic Rasayana medicine, Sonitha Amritha Rasayanam. The medicine is used for purifying the blood and for skin diseases. Methods: The medicine was procured from standard Ayurvedic vendor at Chennai and was subjected to GC-MS analysis with due procedure. Results: The GC-MS profile...

Objective: The present study deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one famous nerve stimulating tonic, Dhanwantari Rasayanam. This knowledge of the molecules present in this medicine could indicate the mechanism of action of this medicine, which is basically used to treat nerve-related disease such as paraplegia, h...

Objective: The study aims at understanding the types of molecules present in one Ayurvedic formulation, Dantyarishtam by GC MS analysis. Methods: Dantyarishtam was procured from standard Ayurvedic vendor at Chennai and was subjected to GC MS analysis by standard procedure. Results: The GC MS profile indicated the presence of some important biomolec...

Objective: The present deals with the gas chromatography-mass spectrometry (GC-MS) analysis of one Ayurvedic digestive formulation, Ashtachurnam. Materials and Methods: Ashtachurnam was procured from standard Ayurvedic vendor from Chennai and was subjected to GC-MS analysis following standard procedure. Results: Some important biomolecules such as...

Objective: The study envisages finding the molecules present in one Ayurvedic medicine, Avipathi churnam, which is prescribed to treat digestive disorders by gas chromatography-mass spectrometry (GC-MS) analysis. Materials and Methods: Avipathi churnam was procured from standard Ayurvedic medicine vendor at Chennai, India, and was subjected to GC-M...

This is the report of antiarthritic role of Sahacharadi kashayam.

The present report deals with the phytochemical and antioxidant activities of various extracts of the leaves of one medicinal plant of importance, Arkaraga (Vitex negundo). In Ayurveda Vitex negundo is known as Nirgundi, meaning "protects the body from all diseases". The water, ethanol, methanol and hexane extracts of leaves were subjected to phyto...

The present study measures the three antioxidant assays, namely, ABTS, DPPH and FRAP by standard protocols for one Ayurvedic medicine, which is used to treat diseases like to treat weak digestion, vomiting, diarrhoea, indigestion, dysentery, irritable bowel syndrome etc. The IC50 value for ABTS radical scavenging effect of Kutajarishtam was found t...

Efficacy study of Ayurvedic medicine

Objective: There is an urgent need to substantiate scientifically the roles of contemporary and native medicinal practices. This exercise will open up a new class of drugs which could be cheap, easily affordable, and with less or no side effects. Moringa oleifera or drumstick is known to a wonder herbal plant and most of its parts are used to cure...

Objective: Anuthailam, an Ayurvedic oil used for the treatment of diseases related to the brain, nose, sinus, eyes, head, neck, shoulders, and arms. Anuthailam is subjected to Gas chromatography–mass spectrometry (GC-MS) analysis to understand the molecules present therein. Materials and Methods: Anuthailam was bought from a standard Ayurvedic vend...

Introduction: The present work deals with the gas chromatography (GC)–mass spectrometry (MS) analysis of Drakshadi Kashayam, which is used in the treatment of Panduroga (anemia), jaundice, and diseases caused due to imbalance in Pitta (bile) consistency. Methods: Drakshadi Kashayam was bought from a standard Ayurvedic vendor at Chennai and subjecte...

Introduction: The present work deals with the gas chromatography–mass spectrometry (GC–MS) analysis of Ksheerabala Thailam which is an Ayurvedic oil used for the treatment of Vata disorders such as neuromuscular pains, sciatica, spondylitis, paralysis, myalgia, for nerve regeneration, cataract, earache, and headache. Materials and Methods: Ksheerab...

Introduction: This study aims to know the types of biomolecules present in Eladi Kera Thailam and to correlate their possible medicinal roles supporting Eladi Kera Thailam’s role as medicine. Methods: Eladi Kera Thailam was bought from a standard Ayurvedic vendor at Chennai and subjected to gas chromatography/mass spectrometry (GC/MS) analysis by s...

Introduction: The present work deals with the gas chromatography–mass spectrometry (GC-MS) analysis of Kutajarishtam which is used in the treatment of diarrhea, dysentery, irritable bowel syndrome, Crohn’s disease, hemorrhoids, etc. Materials and Methods: Kutajarishtam was bought from a standard Ayurvedic vendor at Chennai and subjected to GC-MS an...

Objective: The present study deals with the gas chromatography–mass spectrometry (GC–MS) analysis of an anti-obesity Ayurvedic medicine, Lohasava. Methods: Lohasava was bought from a standard Ayurvedic vendor at Chennai and subjected to GC–MS analysis by standard procedures. The medicinal roles of the biomolecules indicated in the GC–MS profile wer...

Introduction: The present study deals with the gas chromatography–mass spectrometry (GC–MS) analysis of an Ayurvedic oil Triphaladi Thailam, which is used to treat spilt hair, headache, sinusitis, and rhinitis and also for diseases related to neck, eyes, ear, and throat and to understand the molecular roles of this medicine. Methods: Triphaladi Tha...

Objective: The aim of the study is to understand the efficacy of Ayurvedic medicine by subjecting it to gas chromatography–mass spectrometry (GC-MS) analysis. This knowledge could help in finding the molecules that are of medicinal importance. Materials and Methods: Mahamasha Thailam was bought from a Standard Ayurvedic vendor at Chennai and subjec...

Objective: The scientific validity of contemporary and alternative medicinal forms such as Ayurveda and Siddha is of prime importance in today’s world. Materials and Methods: Gas chromatography–mass spectrometry (GC-MS) study of one pain relieving Ayurvedic oil, Karpooradi Thailam and to correlate its medicinal activity with the biomolecules presen...

Objective: The present study deals with the preliminary phytochemical and gas chromatography–mass spectrometry (GC–MS) analysis of different leaf extracts of one medicinal Carissa carandas. Materials and Methods: The phytochemical and GC–MS study of one medicinal plant, C. carandas was done as per standard protocols to correlate its medicinal activ...

Objective: The scientific validation of ethnopharmacologically important herbal plants by latest techniques is necessary to understand their medicinal efficacy. Methods: Gas chromatography–mass spectrometry study of one herbal plant, Dodonaea viscosa var. angustifolia was undertaken by standard procedures and its medicinal activity was verified wit...

The present study is to report the various problems faced during TLC methodology. Although used regularly some technical aspects must be kept in mind to get better and uniform results. During our experiments with TLC methods we came across some problems and here these aspects of TLC methodology are being highlighted. It is suggested that the solven...

Objective: The aim of the study is to understand the efficacy of Ayurvedic medicine by subjecting it to gas chromatography-mass spectrometry (GC-MS) analysis. This knowledge could help in finding the molecules that are of medicinal importance. Materials and Methods: Mahamasha Thailam was bought from a Standard Ayurvedic vendor at Chennai and subjec...

Application of computational tools in medical science can assist physicians with analysis of disease. Herein, prediction based on a subset featured approach with the Siddha medical treatment dataset is utilized for peptic ulcers, using a simple linear regression (LR) based model as predictor, and measuring its effectiveness via error estimates and...

Aragwadharishtam is an Ayurvedic preparation used mainly to detoxify the body. Its main use is in the cure of skin diseases, ulcers and piles. The present study deals with the GC MS analysis of Aragwadharishtam to know the presence of phytochemicals present in this medicine. The GC MS profile indicated the presence of some very important molecules...

Aragwadharishtam is an Ayurvedic preparation used mainly to detoxify the body. Its main use is in the cure of skin diseases, ulcers and piles. The present study deals with the GC MS analysis of Aragwadharishtam to know the presence of phytochemicals present in this medicine. The GC MS profile indicated the presence of some very important molecules...

The present study deals with the GC MS analysis of one Ayurvedic prepaation, Vasakadyarishtam, which is a mucolytic medicine used for the treatment of cough, cold, chest congestion asthma and related diseases like bronchitis, inflammation and hemoptysis. The most important constituent of this medicine is Vasaka or Adhatoda vesika plant, which is kn...

Objective: The present study deals with the antioxidant assays of the different leaf extracts of two medicinal plants, Sphaeranthus indicus and Psophocarpus tetragonolobus. Methods: Dried leaves of S. indicus and P. tetragonolobus were packed in separate round bottom flasks for sample extraction using ethanol, methanol, hexane, and distilled water...

Objective: The present study deals with the antioxidant assays of the different leaf extracts of two medicinal plants, Sphaeranthus indicus and Psophocarpus tetragonolobus. Methods: Dried leaves of S. indicus and P. tetragonolobus were packed in separate round bottom flasks for sample extraction using ethanol, methanol, hexane, and distilled water...

Objective: The objective of this study was to prepare copper nanoparticles (Cu-NPs) of Ayurvedic formulation, Triphala Churna, their characterization, and their antimicrobial activities as compared to Triphala Churna. Materials and Methods: Cu-NPs were prepared using Cu sulfate (CuSO4. 5H2O) and Triphala Churna, which is a mixture of dried powders...

Objective: Verification of the herbal plants by latest scientific tools toward understanding the molecular mechanism underlying their medicinal role is the need of the hour. Methods: Gas chromatography–mass spectrometry study of water extracts of the leaves of one herbal plant, Aristolochia indica was undertaken by standard procedures and its medic...

Objective: The present study deals with the antioxidant study of one Ayurvedic medicine Aswagandhrishtam by three different methods, namely reducing power, 2,2-diphenyl-1-picrylhydrazyl (DPPH), and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. Methods: Aswagandharishtam, which is a liquid medicine, was taken as such at variou...

Aswagandharishtam is classical medicine for diseases pertaining to nervous system and digestive system prepared by a number of plants and plant parts. The present work is to know the types of biomolecules present in it by GC MS analysis. Aswagandharishtam was procured from standard Ayurvedic outlet and was subjected to Gas Chromatography Mass Spect...

Amrithamehari churnam is an Ayurvedic preparation for the treatment of diabetes. The present study is to understand the antioxidant activity of this medicine. Three different types of antioxidant studies were conducted namely, ABTS, DPPH and FRAP. The results clearly indicated that Amrithamehari choornam has antioxidant activities only at higher co...

Ayurveda and Sidhha are age old traditional medicinal practices which are being focused of late as alternative to the modern form of medicine due some of their intrinsic advantages such as natural, low cost, easily affordable and with less side effects. The present study is to evaluate the analgesic effect of one Sidhha formulation, Kodasuri veerav...

Standardization of herbal medicines by TLC

Preservation of fruits and vegetables is a challenge for farmers, sellers and processors. Many chemical preservatives are used to increase the shelf life, to reduce the spoilage, to protect from microorganisms. The present study is to address this problem with an age old traditional preservative, turmeric, as bio preservative. Aqueous solution of t...

Ayurvedic and other traditional forms of medicines require standardization to bring them at par with modern molecular medicine. The present study is to use thin layer chromatographic technique to understand the presence and variation of four important secondary metabolites namely, steroids, terpenoids, flavoniods and alkaloids in the Ayurvedic prep...

Commercial use of turmeric water solution to increase the shelf life of tomato is suggested with our experimental findings

The two medicinal plants namely, Moringa oleifera and Tribulus terrestris are well known for their medicinal roles ethnobotanically. The present work is to understand the presence of phytochemicals in each of them by TLC method and by GC MS analysis. The antibacterial study was also conducted for both the plants. The TLC profiles show the presence...

Aim: Sahachardi Kashayam is an ayurvedic preparation used for the treatment of nerve related diseases like paraplegia, hemiplegia, epilepsy, backache, palsy etc. This is prepared by three plants namely, Sahachara (Barleria prionitis/ Strobilanthes heynianus), Suradaru (Devadaru) (Cedrus deodara) and Sunthi (Zingiber offcinale). The present study is...

Phytochemical and GC MS analysis of on herbal plant

The present study deals with the phytochemical and GC MS analysis of on medicinal plant, Psophocarpus tetragonolobus, which is commonly used in Ayurveda and sidhha forms of medicinal practice. Ethanol, methanol, hexane and water extracts of leaves of P. tertagonolobus were studied for the presence of various phytochemicals present therein. The GC M...

The present study deals with the phytochemical and GC MS analysis of on medicinal plant, Psophocarpus tetragonolobus, which is commonly used in Ayurveda and sidhha forms of medicinal practice. Ethanol, methanol, hexane and water extracts of leaves of P. tertagonolobus were studied for the presence of various phytochemicals present therein. The GC M...

Aim: Sahachardi Kashayam is an ayurvedic preparation used for the treatment of nerve related diseases like paraplegia, hemiplegia, epilepsy, backache, palsy etc. This is prepared by three plants namely, Sahachara (Barleria prionitis/ Strobilanthes heynianus), Suradaru (Devadaru) (Cedrus deodara) and Sunthi (Zingiber offcinale). The present study is...

Indian herbal medicines have served as major source of medicine for prevention and treatment of many diseases including microbial infections. Emergence of multidrug resistance has limited the therapeutic options for antibiotics in the world. Hence, monitoring resistance is of paramount importance. The use of traditional herbal medicines in crude or...

The present study deals with the GC MS analysis of Ethyl acetate extract of the plant Aloe barbadensis. The plant was collected from Moonaru hills, Kerala. Its color was red and the jelly inside also was blood red in color. The difference of this plant from the common Aloe vera has prompted us to go for the GC MS analysis to find whether any major...