Muayad Alzuabi

Medical University of South Carolina | MUSC · Neurology

Objectives To empirically evaluate five commonly used meta-analysis methods and their impact on imprecision judgements about effect estimates. The two fixed-effect model methods were the inverse variance method based on normal distribution and the Mantel-Haenszel method. The three random-effects model methods were the DerSimonian and Laird, the Har...

Objective To evaluate the magnitude of the association between risk factors and premature myocardial infarction (MI) (men aged 18-55 years; women aged 18-65 years). Patients and Methods We searched MEDLINE and other databases from inception through April 30, 2020, as well as bibliography of articles selected for data extraction. We selected observ...

Objective To summarize the best available evidence comparing open vs. endovascular popliteal artery aneurysm repair. We also summarized the natural history of popliteal artery aneurysms to support of the Society for Vascular Surgery guidelines. Methods We searched MEDLINE, EMBASE, Cochrane databases, and Scopus for studies of patients with poplite...

Introduction: Magnetic resonance imaging (MRI) can characterize carotid plaque features, including intraplaque hemorrhage (IPH), lipid-rich necrotic core (LRNC), and thin/ruptured fibrous cap (TRFC), that have increased tendency to cause future cerebrovascular ischemic events. We performed a systematic review and meta-analysis of studies evaluatin...

Background: Aspirin is almost always used after coronary artery bypass graft (CABG) surgery; however, it is unclear what optimal dose should be prescribed. In this systematic review, we evaluated the effects of high versus low-dose aspirin in patients after CABG. Methods: A comprehensive database search was conducted in several databases from da...

Background: Excess adipose tissue is associated with an abnormal lipid profile that may improve with weight reduction. In this meta-analysis, we aimed to estimate the magnitude of change in lipid parameters associated with weight loss in adults who are overweight or obese. Methods: We searched MEDLINE, EMBASE, Cochrane Database of Systematic Rev...

Three key management decisions in autoimmune hepatitis concern the use of budesonide and azathioprine as first‐line therapy, the choice of mycophenolate mofetil or calcineurin inhibitors for patients failing steroids and azathioprine, and the role of maintenance steroids in prevention of recurrence after liver transplantation. To address these ques...

Background: Surveillance imaging of previously unruptured, coiled aneurysms remains routine even though reports of rupture of these aneurysms are extremely rare. Purpose: We performed meta-analysis to examine long-term rupture risk over ≥1-year follow-up duration in patients with unruptured intracranial aneurysm who underwent endovascular therap...

To evaluate the effectiveness of an admixture of ketamine and propofol on peri-induction hemodynamics during airway manipulation, we searched electronic databases of randomized controlled trials from January 1, 2000, to October 17, 2018. Trial screening, selection, and data extraction were done independently by two reviewers with outcomes pooled ac...

This cohort study examines outcomes of patients with brain cancer to provide demographic details on the increase in suicide rate after brain cancer diagnosis.

Introduction Management approaches for intracranial atherosclerosis include medical, surgical, or endovascular treatment. Among endovascular treatments, recent studies have stated that submaximal angioplasty (SA) may offer considerable benefits and be a promising alternative to aggressive medical therapyand/or stenting in the treatment of intracran...

Introduction: To determine the association between magnetic resonance imaging (MRI)- detected vulnerable Carotid Plaques and clinical presentation related to ipsilateral carotid artery territory. Evidence acquisition: We searched three databases including Ovid MEDLINE, Ovid EMBASE, and Scopus from 2000 to 2018 for studies that evaluated vulnerab...

Background Glioblastoma is one of the most aggressive brain malignancies in adults with limited data evaluating the racial disparities in incidence or mortality. In this study, we aim to study the temporal trends of incidence and mortality and assess ethnic impact on the outcomes. Methods We used the SEER database to study glioblastoma cases in th...

Background: Glioblastoma multiforme (GBM) patients with a prior malignancy are usually excluded from clinical trials on GBM based on the assumption that this history will affect their survival outcomes. This practice may affect clinical trial accrual and limit the gathering of knowledge essential to the formulation of therapeutic options for this p...

Introduction Neonates with hypoxic ischemic encephalopathy (HIE) who undergo therapeutic hypothermia (TH) remain at high risk for electrographic seizures (ES) that frequently lack clinical signs. These subclinical seizures necessitate the use of resource-intensive continuous video-EEG monitoring (cEEG) for their detection. We assessed the prevalenc...

The intervertebral disc (IVD) is a joint unique in structure and functions. Lying between adjacent vertebrae, it provides both the primary support and the elasticity required for the spine to move stably. Various aspects of the IVD have long been studied by researchers seeking a better understanding of its dynamics, aging, and subsequent disorders....

Hashimoto encephalopathy (HE) is a controversial autoimmune disorder, probably underdiagnosed, that causes a wide variety of neurological manifestations. Symptoms differ among patients and may be very severe in some cases. However, it can be treated, with a very good prognosis. In our case, a teenaged girl with a family history of migraine, vitilig...