Mr. Utkalendu Suvendusekhar Samantaray

Aurigene Discovery Technologies · Aurigene Bangalore

Chimeric antigen receptor based therapy is the most promising and new treatment for cancer. This therapy is very effective in many types of cancer. And the most innovative part of this treatment is that it can be considered the most effective treatment when other treatments get failed. This treatment gives the most satisfying results and the s...

CRISPR Clustered regularly interspaced short palindromic repeats. CRISPR-associated protein (Cas) technology for site-specific genome editing has been used to precisely induce mutagenesis in a variety of plant species, including rice. Because Cas9 causes blunt-ended double-strand breaks, which are then repaired without substantial end-processing, a...

VLPs are the most self-centered particles; these particles have a defined structure that helps in making safe and effective vaccines for a deadly virus like Dengue. The morphology of these particles is highly immunogenetic in nature. As a result, the vaccines made from these particles are less infectious and do not have any kind of risk associat...

Pathogenic, slow-growing Mycobacterium tuberculosis and other Mycobacterium tuberculosis complex (MTBC) species include the pe/ppe genes. In the pathogen-host connection, these genes are crucial. Despite the fact that the activities of most PE/PPE family proteins are unknown, mounting evidence shows they play a role in M. tuberculosis infection. Th...

Coronavirus spreads from human to human or human to animal via airborne droplets. Coronavirus penetrates human cells via the membrane ACE-2 exopeptidase receptor. There are no specific anti-virus medi- cations or vaccinations available to treat this sudden and fatal sickness during COVID-19 except vaccination. Still, it will take months, if not yea...

Basic human biology is dealt with by mRNA, which creates instructions for making proteins that may aid in the fight against infectious illnesses using our bodies' own mechanisms. mRNA therapies are neither tiny compounds nor huge biological such as recombinant proteins or monoclonal antibodies. These are a series of instructions that assist our cel...

Generally, a gene which is inserted directly into a cell does not operate independently. Instead, the transmission of the gene is genetically modified by a biological messenger called a vector, consists of a transgene and a large DNA sequence as a backbone. Since they can deliver the new gene by infecting the cell, such viruses are also used as vec...

Furin controls the activation of various types of functional proteins by cleaving inactive protein precursors in the secretory pathway. It aids in the cleavage of unwanted sequence segments and the isolation of the active portion of a protein of interest. However, not all furin cleavage sites are the same. Furin activates a wide range of substrates...

Zinnia (Zinnia elegans Jacq.) occupies a pristine place in the garden for its bright colours and long flowering period. Zinnias are propagated by seeds hence genetic variation and a tendency for stock plants to decline in vigor over time is high. Young internodal explants of this species were grown on modified Murashige and Skoog (MS) medium supple...

Fish account fifty percent of entire vertebrates present on the planet. They can be found practically in every possible aquatic habitats; from the 39,900 species of vertebrates, 21,723 are fishes with 8,411 being freshwater species while 11,650 being marine. There are about 2,500 species of fishes are present in India out of which 930 of them livin...

Marine fish are well-known for being a high-quality protein source having high concentration of essential amino acids. It has high concentration of mono unsaturated and poly unsaturated fatty acids, which may aid in the optimization of lipid profiles and the reduction of the risk of coronary heart disease (CHD). The goal of this study was to estima...

Cellulose undergoes hydrolysis utilizing chemicals to deliver glucose, which might be utilized for the production of ethanol, organic acids, and various chemicals. Cellulases are a collection of hydrolytic catalysts that can hydrolyze the most plentiful natural polymer for example cellulose into smaller sugar components including glucose subunits....

Human trials of the COVID-19 vaccine have shown a lot of adverse effects, which created a question mark on vaccine development and emergency approval. In fact, more than 170 companies are working day and night to develop an effective and safe COVID-19 vaccine, which can minimize the adverse effects and simultaneously can improve adaptive immunity....

This review describes the latest advancements on polysaccharide conjugate vaccine against pneumococcal invasive diseases as well as the current vaccine recommendations in children and adults. Every year, pneumococcal infections are becoming more dangerous and specifically during this COVID-19 pandemic, the mortality rate has been increased substant...

Coronavirus spreads from human to human or human to animal via airborne droplets. Coronavirus penetrates human cells via the membrane ACE-2 exopeptidase receptor. There are no specific anti-virus medications or vaccinations available to treat this sudden and fatal sickness during COVID-19 except vaccination. Still, it will take months, if not years...

Corona virus spreads from human to human or human to animal via airborne droplets. Corona virus penetrates human cells via the membrane ACE-2 exopeptidase receptor. There are no specific anti-virus medications or vaccinations available to treat this sudden and fatal sickness during COVID-19 except vaccination. Still, it will take months, if not yea...

The Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2, formerly known as 2019-nCoV, the causative pathogen of Corona virus Disease 2019 (COVID-19) is a major source of disaster in the 21th century. In the second meeting of the Emergency Committee, the World Health Organization (WHO) declared that COVID-19 is a “public-health emergency of...

Probiotics are the live micro-organisms such as; bacteria or yeasts classified under good and beneficial bacteria for humans and animals. Inside the animal gut especially in the large intestine, there are thousands of naturally occurring bacteria acting positively for the animal health, reducing the activities of harmful bacteria. However, the rese...

The molecular properties of Indian medicinal plants have shown promising results to reduce the inflammation and allergic infections in human beings as per many clinical studies. Recently, the common priorities have been developed to discover traditional therapeutics having significant and pure molecular activities to be useful against the anti-infl...

This research has been focused on the effect of phytochemicals in treating the COVID- 19 and a serious medicine can be developed to minimize the DNA replication as well as transcription. Phytochemicals are compounds that are produced by plants ("phyto" means "plant"). They are found in fruits, vegetables, grains, beans, and other plants parts. E.g....