Mozaniel Santana Oliveira

• PhD
• Researcher at Museu Paraense Emilio Goeldi - MPEG

Atmospheric pollution, driven by the emission of toxic gases, represents an environmental and public health challenge. This study presents molecular docking simulations using non-metallic (Pc) and metallic (MPc) phthalocyanines of iron (FePc), cobalt (CoPc), copper (CuPc), zinc (ZnPc), and titanium (TiPc), aiming at their application in the capture...

Determining the optimal harvest time for Pentaclethra macroloba seeds is essential to preserve germination potential and ensure high-quality oil production, valued in the pharmaceutical and cosmetic industries. This study aimed to identify the maturation phase that maximizes seed physiological quality and oil yield. Fruits and seeds were collected...

The development of environmentally friendly pesticides and antibiotics is critical due to increasing resistance to conventional agents and rising concerns about human health and environmental impact. This study aimed to evaluate the nematicidal, phytotoxic, and antibacterial properties of acetone extracts from various parts of Alpinia malaccensis....

Digitalis purpurea L. is traditionally valued for its cardiac glycosides, but its pesticidal properties remain underexplored. This study evaluated its nematicidal efficacy against Meloidogyne incognita, focusing on acetylcholinesterase (AChE) inhibition as a potential mechanism. Extracts obtained using Soxhlet extraction with hexane (DPHE), dichlor...

This study presents a comprehensive chemical analysis of the essential oil isolated from Senega longicaulis, and aroma analysis of Senega adenophora and Senega appressa, employing both fresh and dried samples. Notable differences were observed between the fresh and dried samples of essential oil from S. longicaulis. In the fresh sample, the predomi...

Hedychium coronarium, commonly referred to as the white ginger lily, is esteemed for its ornamental characteristics and fragrant properties. However, its potential as a natural insecticide remains inadequately explored, particularly regarding the influence of seasonal variations on its chemical composition. The aim of this study was to investigate...

This study includes a comparative investigation to analyze the phytochemical composition, nematicidal efficacy, in vitro AChE inhibitory activity, and molecular docking study of Leucosceptrum canum. (LC) extracts. Various polarity solvent extracts including hexane (LCHE), dichloromethane (LCDE), and methanol (LCME) were prepared from LC aerial part...

This review aims to evaluate the mechanisms of action of current and emerging anti-TB drugs and molecules, emphasizing hydrazone functionality. Hydrazone compounds, featuring an azomethine group (R 1-HN-N=CR 2 R 3), exhibit potent anti-TB and broad-spectrum anti-infective properties. It includes the synthesis and biological testing of hydrazide-hyd...

Digitalis purpurea L., commonly referred to as foxglove, is a biennial herbaceous plant indigenous to Western and Central Europe and has become widely established in temperate areas across the globe. Renowned for its vibrant bell‐shaped flowers, D. purpurea has a long‐standing history of medicinal use, particularly for treating cardiovascular issue...

This study presents the first complete analysis of the chemical composition of the flowers of the species N. fragrans and N. microchila. The compounds were extracted via distillation and simultaneous extraction and analysed using gas chromatography coupled to mass spectrometry. A total of 82 compounds were identified and the results reveal signific...

Carotenoids are secondary metabolites chemically classified as fat-soluble tetraterpenes. These compounds are produced by both photosynthetic organisms, including plants and microalgae, and non-photosynthetic organisms, such as bacteria and fungi. Carotenoids come in various colors, ranging from red hues to orange and yellow. These colors derive fr...

Carotenoids are naturally occuring pigments, produced by plants, microalgae, bacteria and fungi. It plays a key role in various physiological functions of living organisms. Carotenoids are particularly useful because of their versatile application from bioactive compounds (supplement, cosmetic) to colouring agents (Food and beverages, Animal and Fi...

This study investigates the potential of methyl eugenol (ME), a compound found in the essential oils of various plants, to inhibit oxidative stress and its impact on diseases associated with this process. ME has been shown to possess antioxidant properties and antiproliferative activity in several cancers. It also demonstrates neuroprotective poten...

Carotenoids are one of the most important groups of bioactive compounds in nature. They have been used in the food, cosmetic and pharmaceutical industries due to their wide range of chemical and biological properties. Currently, industrial use of carotenoids comes from chemical synthesis, but greener and biotechnological engineering approaches for...

Oxidative stress is a pivotal factor in the pathogenesis of malaria, contributing to the development of conditions such as anemia, respiratory complications, and cerebral malaria. To counteract oxidative damage, we evaluated the effects of vitamin E (α‐TOH) and D‐α‐tocopherol polyethylene glycol succinate 1000 (TPGS) supplementation on parasitemia...

Lantana camara is weed with a wide range of chemical constituents, including primary and secondary metabolites such as alkaloids, flavonoids, tannins, saponins, and terpenoids. These compounds contribute to its medicinal and pesticidal potential. The essential oils and different solvent fractions derived from L. camara exhibit notable variations in...

Cyanobacteria, a group of photosynthetic bacteria capable of converting sunlight and carbon dioxide into organic compounds, are being explored as a potential source for the production of biofuels. They have the ability to produce various types of biofuels, such as ethanol, hydrogen, and biodiesel. This study is a systematic review of scientific art...

Euphorbiaceae is one of the largest families of angiosperms, distributed globally. Several Euphorbiaceae species produce essential oils, which are characterized by different chemical profiles and biological properties, as reported in previous literature. This review covers articles published between 2012 and 2023 that describe essential oils extrac...

Euphorbiaceae is one of the largest families of angiosperms, distributed globally. Several Euphorbiaceae species produce essential oils, which are characterized by different chemical profiles and biological properties, as reported in previous literature. This review covers articles published between 2012 and 2023 that describe essential oils extrac...

Three labdane-type diterpenes, namely coronalactoside i, hedychilactone a, and (E)-labda-8(17),12-dien-15(16)-olide, along with the flavonoid glycoside isolinariin a, were isolated from Heydichium coronarium. Structural elucidation employed spectroscopic techniques (iR, mS, nmR, and dEpt) and comparison with literature data. pesticidal and antimicr...

This work characterizes microemulsions of Medicago marina essential oil and evaluates their antimicrobial, antibiofilm, and anticoagulant effects. Medicago marina L. aerial parts essential oil was hydro-distilled and analyzed by gas chromatography-FID and gas chromatography/mass spectrometry (GC/MS) for the first time from the Tunisian chemotype. T...

Hedychium coronarium plant has attracted considerable attention from researchers due to its diverse phytochemical composition and potential therapeutic applications. The objective of this study was to evaluate the phytochemical profile and biological attributes of H. coronarium essential oils collected during different seasons in the Kumaun region...

Plants are a great source of bioactive compounds. Many such bioactive compounds are considered as extra nutritional constituents and typically occur in foods in small quantities. Capsaicinoids are a group of such compounds with many nutritional and health benefits. Capsaicinoids are amides present in Capsicum species, which are secondary metabolite...

Oleaceae (olive family), includes 28 genera and about 700 species. Nevertheless, there remains a lot to uncover about the group’s historical development, the evolution of various reproductive and dispersal mechanisms, and polyploidization episodes appear to be linked to its diversification. In the current study, foliar epidermal anatomy of 13 plant...

Volatile oils or essential oils (EOs) were extracted from three V. sebifera samples (labeled as A, B, and C) in September 2018 and February 2019; the extraction process involved hydrodistillation of the leaves. The chemical compositions of the EOs were analyzed using gas chromatography-mass spectrometry (GC/MS). The volatile components were identif...

Context: The Omicron, Kappa, and Delta variants are different strains of the SARS-CoV-2 virus. Graphene oxide quantum dots (GOQDs) represent a burgeoning class of oxygen-enriched, zero-dimensional materials characterized by their sub-20-nm dimensions. Exhibiting pronounced quantum confinement and edge effects, GOQDs manifest exceptional physical-c...

The present study provides a comprehensive analysis of the chemical composition of essential oils from species of the Myrcia genus and their applications. The compiled results highlight the chemical diversity and biological activities of these oils, emphasizing their potential importance for various therapeutic and industrial applications. The find...

Palynology, a prominent field in plant systematics and biodiversity studies, plays a vital role in identifying and determining the plant species present in a specific region. The current study was performed to evaluate the micromorphological traits of pollen from flora of Lesser Himalaya. Pollen microstructural variations aid in the identification...

Myrciariatenella O.Berg, a native plant species of Brazil, exhibits pharmacological applications, including antitumor activity. In this study, we isolated the essential oil (EO) of M. tenella and identified its phytochemical profile. In addition, we determined the in vitro and in silico cytotoxic activities of EO in nontumor and tumor cell lines (g...

Biorationals or biopesticides are pest control agents of biological origin. Biopesticides are emerging alternatives to harmful chemical pest control agents. The book provides essential information on botanical, biological originated insecticidal, herbicidal, fungicidal, nematicidal agents, insect growth hormones, insect pheromones and plant growth...

The essential oils and aroma derived from the leaves (L), stems (St), and spikes (s) of Piper nigrum L. cv. Guajarina were extracted; the essential oils were extracted using hydrodistillation (HD), and steam distillation (SD), and the aroma was obtained by simultaneous distillation and extraction (SDE). Chemical constituents were identified and qua...

Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches presents an in-depth exploration of the multifaceted relationships between medicinal plants and human health. This comprehensive volume delves into the intricate chemical and biochemical aspects of plants, shedding light on their pharmacological properties and applications. Wi...

Graphene oxide quantum dots (GOQDs) represent a burgeoning class of oxygen-enriched, zero-dimensional materials characterized by their sub-20 nm dimensions. Exhibiting pronounced quantum confinement and edge effects, GOQDs manifest exceptional physical-chemical attributes. This study delves into the potential of graphene oxide quantum dots, elucida...

Fibromyalgia (FM) is characterized by chronic pain and heightened sensitivity to painful stimuli. This study investigated the potential of Niranthin (NR), a natural compound derived from Phyllanthus species, in a rat model of FM. We employed a multifaceted approach to comprehensively assess the potential benefits of NR as a treatment for FM, includ...

Pentaclethra macroloba (Willd.), whose common name is “pracaxi,” is naturally found in the Amazon region. The present study is aimed at analyzing the anatomy, seed histochemistry, and chemical composition in fatty acid profile of P. macroloba seed oils. Seeds were collected in the cities of Belém, Marituba, and São Domingos do Capim-PA. For the stu...

Neglected tropical diseases (NTDs) are prevalent in tropical and subtropical countries, and schistosomiasis is among the most relevant diseases worldwide. In addition, one of the two biggest problems in developing drugs against this disease is related to drug resistance, which promotes the demand to develop new drug candidates for this purpose. Thu...

(1) Background: The severity of malaria is associated with low bioavailability of antioxidants and high concentration of free radicals that induce oxidative damage in cerebral and pulmonary microcirculation. This can be prevented by the action of consumable antioxidants present in foods. Therefore, we investigated the protective role of lycopene (L...

Plant extracts are considered as a promising alternative to chemical pest control agents. The chemistry of plant extracts varies with several environmental as well as geographical factors. Zingiber roseum (Roxb.) Roscoe also known as "Rosy Ginger" and "Jangli Adrak" is one of the most important aromatic and medicinal plant of family Zingiberaceae....

ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/tbsd20

Plectranthus ornatus is a medicinal and aromatic plant used in traditional and alternative medicine. In this study, leaves of P. ornatus were collected in two cities of the state of Pará, “Quatipuru” and “Barcarena”, and were used with the objective of analyzing, through morphoanatomical data and histochemical and phytochemical studies of essential...

Copaíba oil-resin is extracted from the trunk of the Copaíba tree and has medicinal, cosmetic, and industrial properties. As a result, widespread knowledge about the use of Copaíba oil-resin has evolved, attracting the scientific community’s attention. This paper aims to map the global knowledge production regarding the biological activities of Cop...

Chemical composition of the essential oils (EOs) from the leaves of five Annonaceae species found in the amazon region was analyzed by Gas chromatography coupled to mass spectrometry. The antifungal activity of theses EOs was tested against Candida albicans, Candida auris, Candida famata, Candida krusei and Candida tropicalis. In addition, an in si...

A new series of 20 benzofuran based sulphonamides was synthesized from salicylaldehyde and ortho-vanillin. Synthesized compounds (VIIIa-VIIIt) were characterized using FT-IR (Fourier-transform infrared spectroscopy), 1 H-NMR (Proton nuclear magnetic resonance) and Mass spectroscopic studies. All 20 compounds were subjected to in vitro antitubercula...

The essential oils (OEs) of the leaves, stems, and spikes of P. marginatum were obtained by hydrodistillation, steam distillation, and simultaneous extraction. The chemical constituents were identified and quantified by GC/MS and GC-FID. The preliminary biological activity was determined by assessing the toxicity of the samples to Artemia salina Le...

The increasing number of multidrug-resistant bacteria poses a serious threat to global health problems. The lack of new antibiotics has led to the search for potential alternative strategies. Understanding the antibacterial mechanisms of cinnamon essential oil and its active ingredients is essential to enhance it as a potential new source of antibi...

Nervous system diseases in the central nervous system, peripheral nervous system, and autonomic nervous system lead to sensory, motor, consciousness, and autonomic dysfunctions, which are the main manifestations of these diseases. They have a marked impact on a patient’s life and work. In medicine, cinnamon has the function of “nourishing the prima...

Cinnamon has been used for many years as a food additive and as a source of bioactive compounds to improve the quality of life of humans. However, it is important to report that these products can be adulterated and lose quality. Toxicity of this food condiment can cause intoxication; therefore, research is necessary to analyze the quality of cinna...

Viral diseases are still one of the major threats to human health all over the world. Novel coronavirus (SARS-CoV-2) is spreading rapidly in most parts of the world, not only threatening serious illness or death to anyone infected, especially the elderly or those in poor health, but also striking a major blow to the global economy. There is no spec...

Compared to traditional medicine, herbal medicines have a long history of treating and preventing diseases, including diabetes. Cinnamon has been used as a spice and traditional herb for centuries. Existing in vitro and animal experimental evidence shows that cinnamon has anti-inflammatory, antibacterial, antioxidative, and antitumor biological act...

The liver is one of the five organs of the human body with a metabolic function in humans. From the perspective of metabolism, the main functions of the liver include amino acid metabolism, hormone metabolism, secretion and excretion of bile, and detoxification. With the improvement of people’s living standards, various overprocessed foods increasi...

Aflatoxin is a class of secondary metabolites mainly produced by Aspergillus flavus and Aspergillus parasitica. It is highly toxic and carcinogenic. Its toxicity is 10 times that of potassium cyanide and 68 times that of arsenic. Aflatoxin intake can cause acute hepatitis, hepatocyte necrosis, and liver cancer and seriously harm human and animal he...

Spices are defined as aromatic substances, which serve as raw materials in the food industry. And this use goes much further, as they have been used since antiquity due to their medicinal principles in the fight against flu and colds and in the reduction of nausea and vomiting. In addition to these benefits, the antioxidant properties present in it...

Alzheimer’s disease (AD) is the most common dementia disorder worldwide. At present, there are no effective treatment strategies to improve or prevent the development of the disease. Over the past few years, various cinnamon varieties and their bioactive ingredients have generated significant interest in cinnamon for the treatment of patients with...

Cinnamon is an important commodity for several countries. Among the more than 250 known species, four have the highest added values: C. zeylanicum sin. C. verum, C. burmannii, C. loureiroi, C. aromaticum. These varieties are responsible for approximately 90% of the world market for the production and sale of manufactured products, such as powder, b...

Cinnamon or cinnamon extract has been widely used as a traditional herbal medicine with medicinal value and has been reported to have various clinical benefits. As for the current research status, the safety evaluation studies of cinnamon or cinnamon extracts are still lacking, and the toxicological studies are not deep enough. Therefore, this pape...

The powdered or unprocessed bark of Cinnamomum species can be sold as cinnamon, but only one species can be considered as true cinnamon. Studies have shown that morphological, molecular, and biochemical aspects can help in the correct identification of species. However, works are still published with inadequate information, or without taxonomic ide...

Cinnamon is an ancient spice used worldwide for commercial purposes in the canning and confectionery industries. This spice belongs to the genus Cinnamomum which has medicinal properties against indigestion, cough cold, and microbial infections. In addition, this genus has species that produce essential oils that present major compounds, such as tr...

Cinnamon has been used as a food flavor for thousands of years. Since the twentieth century, its derivatives have been continuously developed, extracted, and applied. Cinnamaldehyde, cinnamic acid, cinnamon powder, cinnamon essential oil, and other products are all from cinnamon. In this part, we have integrated the edible effects of Cinnamomum, in...

Cinnamon essential oil not only has significant antibacterial activity but also has excellent antioxidant activity. As a natural and green plant source antioxidant, cinnamon essential oil has a very broad application prospect in the food industry and biopharmaceutical field. Therefore, understanding the antioxidant mechanism of cinnamon essential o...

Over the past few decades, the number of drug-resistant fungal infections has been increasing and now poses a serious threat to global health. Despite extensive research into the development of new antifungal agents, only a limited number of antifungal agents are available on the market. These conventional synthetic drugs often have chemical residu...

Cancer remains one of the most serious health threats facing the world. According to the data released by the World Health Organization (WHO), about 10 million people die from cancer every year, accounting for nearly one sixth of the global death toll. In addition, it is worth mentioning that the incidence and mortality of cancer are increasing yea...

Four species of the genus Hedychium can be found in Brazil. Hedychium coronarium is a species endemic to India and Brazil. In this paper, we collected six specimens of H. coronarium for evaluation of their volatile chemical profiles. For this, the essential oils of these specimens were extracted using hydrodistillation from plant samples collected...

Malaria is a serious illness transmitted through the bite of an infected mosquito, which is caused by a type of parasite called plasmodium and can be fatal if left untreated. Thus, newer antimalarials with unique mode of actions are encouraged. Fused pyridines have been vastly reported for numerous pharmacological activities including but not limit...

Te objective of the current study was to evaluate the altitudinal variability in chemical compounds, nematicidal, insecticidal, herbicidal, and antifungal activity of the essential oils of H. coronarium collected from four diferent habitats of Tarai and Kumaun region of Uttarakhand. Essential oils were hydro-distilled from rhizomes of H. coronarium...

Background: Alpinia malaccensis, commonly known as "Malacca ginger" and "Rankihiriya," is an important medicinal plant of Zingiberaceae. It is native to Indonesia and Malaysia and widely distributed in countries including Northeast India, China, Peninsular Malaysia and Java. Due to vide pharmacological values, it is necessary to recognize this spe...

Cannabidiol (CBD), a nonpsychotropic phytocannabinoid that was once largely disregarded, is currently the subject of significant medicinal study. CBD is found in Cannabis sativa, and has a myriad of neuropharmacological impacts on the central nervous system, including the capacity to reduce neuroinflammation, protein misfolding and oxidative stress...

The essential oils (EOs) of Guatteria schomburgkiana (Gsch) and Xylopia frutescens (Xfru) (Annonaceae) were obtained by hydrodistillation, and their chemical composition was evaluated by gas chromatography-mass spectrometry (GC/MS). Herbicide activity was measured by analyzing the seed germination percentage and root and hypocotyl elongation of two...

The essential oils (EOs) of Guatteria schomburgkiana (Gsch) and Xylopia frutescens (Xfru) (Annonaceae) were obtained by hydrodistillation, and their chemical composition was evaluated by gas chromatography-mass spectrometry (GC/MS). Herbicide activity was measured by analyzing the seed germination percentage and root and hypocotyl elongation of two...

Medicinal and aromatic plants are known to have a number of biologically active compounds. Since ancient times, such plants have been used in ethnopharmacology. A number of medicines have been developed from plant origin by researchers and Researchers continue to be interested in plant-based medicines.. Zingiberaceae is a well-known plant family fo...

This study aimed to describe and characterize the biometry of the fruits, and seeds of three species of Solanum (Solanaceae) from the Amazonia. Biometry can help the development of efficient techniques for the management and understanding of the species. The morphometric characterization of the structures was performed from 100 fruits and 100 seeds...

Globba sessilifora Sims is an aromatic rhizomatous herb of family Zingiberaceae which is endemic to Peninsular India. Tis study frst reports the phytochemical profle and pesticidal potential of oleoresins obtained from the aerial and rhizome parts of Globba sessilifora Sims. Te oleoresins were prepared by the cold percolation method and were analyz...

Hedychium coronarium J. Koenig belongs to the family Zingiberaceae, generally known as butterfly ginger, butterfly lily, cinnamon jasmine, garland flower and ginger lily. It is a medicinal plant grown throughout India, Southeast Asian countries, China, Japan, and Brazil. Traditionally, it is used as a febrifuge, tonic, anti-rheumatic, used to treat...

Croton campinarensis Secco, A. Rosário & PE Berry is an aromatic species recently discovered in the Amazon region. This study first reports the chemical profile, antioxidant capacity, and preliminary toxicity to A. salina Leach of the essential oil (EO) of this species. The phytochemical profile of the essential oil was analyzed by gas chromatograp...

Background Hydrazide-hydrazone derivatives have shown diverse biological activities, such as antitubercular (anti-TB), antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal actions. Objectives Hydrazide–hydrazones contain azomethine (–NH–N=CH–) group connected with carbonyl group and are believed to be responsible...

Over the years, natural products such as essential oils have been gaining more and more prominence due to their perceived health benefits. Plants rich in essential oils represent a viable source of biomolecules for use in the most varied human activities, such as agricultural, cosmetic, and pharmaceutical applications. Essential oils are natural vo...

Terpenoids are commercially important chemicals found in essential oils and other natural plant sources. They are used in solving issues that affect agricultural production, making them a key component of sustainable agronomy. Terpenoids: Recent Advances in Extraction, Biochemistry and Biotechnology provides information about the varied use of terp...

Background Essential oils (EOs) are plant-derived volatile and aromatic extracts with diverse biological effects like antibacterial, anti-inflammatory, and antioxidant properties. Recently, consumers' perceptions of synthetic preservatives have grown unfavorable, spurring research in EOs and their application in food preservation and packaging of v...

The essential oils (EOs) of Myrciaria floribunda (Mflo) and Myrcia sylvatica (Msyl) (Myrtaceae) were obtained by hydrodistillation. The analysis of volatile constituents was performed by GC/MS. Preliminary toxicity was assessed on Artemia salina Leach. The antioxidant capacity was measured by the ABTS•+ and DPPH• radical inhibitory activities. The...

Nepeta hindostana, commonly known as the North Indian Catmint, is an important Indian aromatic and medicinal plant of family Lamiaceae. Its leaves are extensively used as cardiac tonic and gargle to cure sore throat in the form of extract or decoction. However, there are few reports on the chemical composition and biological activities of leaf esse...