Mozammel Haque BhuiyanUniversity of Southern California | USC · Zilkha Neurogenetic Institute
Mozammel Haque Bhuiyan
Doctor of Philosophy
Postdoctoral Scholar, Zilkha Neurogenetic Institute, University of Southern California
About
17
Publications
4,632
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102
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Introduction
Mozammel does research in Neuroscience, Bio-engineering and Cardiovascular diseases.
Additional affiliations
May 2022 - October 2022
September 2011 - September 2013
Education
June 2018 - December 2022
July 2011 - June 2012
July 2007 - June 2011
Publications
Publications (17)
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a major contributor to physiological and pathological glutamate-mediated Ca2+ signals, and its involvement in various critical cellular pathways demands specific pharmacological strategies. We recently presented γ-hydroxybutyrate (GHB) ligands as the first small molecules selectively ta...
Regeneration of neural tissue and recovery of lost functions following an accident or disease to the central nervous system remains a major challenge worldwide, with limited treatment options available. The main reason for the failure of conventional therapeutic techniques to regenerate neural tissue is the presence of blood-brain barrier separatin...
Stroke remains a leading cause of adult disability with treatments limited to thrombolytic therapies that are severely limited by a narrow therapeutic window. The potential of hundreds of other therapeutic agents cannot be evaluated due to their poor ability to cross the blood-brain barrier. Recently, biopolymer hydrogels have shown promise at over...
Background: Stroke is the leading cause of adult disability worldwide. The primary reason for the lasting functional impairment following stroke is the brain’s limited ability to regenerate after an injury. Treatment measures such as systemic delivery of drugs and growth factors are limited by blood brain barrier and off-target effects. Significant...
Prostate cancer (PCa) is the most common malignancy in men and the leading cause of death for men all over the world. Early diagnosis is the key to start treatment at an early stage of PCa and to reduce the death toll. Generally, PCa expresses characteristic morphologic features and serum biomarkers; however, early diagnosis is challenging due to i...
Biomaterials is an emerging field in the study of brain tissue engineering and repair or neurogenesis. The fabrication of biomaterials that can replicate the mechanical and viscoelastic features required by the brain, including the poroviscoelastic responses, force dissipation, and solute diffusivity are essential to be mapped from the macro to the...
Neolamarckia cadamba, (Roxb.) is commonly grown in different regions of Bangladesh, India also in some other parts of the world. The present study was carried out to evaluate the anti-oxidative and erythrocyte membrane stabilizing effect of fruit extract along with the nutritional values of ripen fresh N. cadamba fruit. The antioxidant potential of...
Alzheimer’s disease (AD) is the most prominent dementia-related disease and characterized by the presence of insoluble amyloid beta peptide (Aβ) fibers in or around the brain neurons of the affected person. Therefore, agent(s) capable of inhibiting brain amyloid deposition might delay the occurrence or retard the progress forwards of AD and related...
We studied on the effect of Curcuma longa extract on spatial learning-related memory ability of old rats in eight-arm radial maze task. Rats were randomly divided into two groups: one group was orally administered 100 mg/KgBW/day C. longa extract (CLE) dissolved in deionized water and the other group was administered the vehicle alone for 10 weeks....
Curcuma longa, commonly known as turmeric, is one of the most studied medicinal plants. The most important active constituent of C. longa is the curcumin, which is responsible for the vibrant yellow color of the turmeric. The yellow pigment curcumin (diferuloylmethane) is a low molecular weight polyphenol which is mostly implicated in the antioxida...
Objective: Raphanus sativus is a hugely used edible root vegetable. We investigated whether the feeding of the
Raphanus sativus hot water extract (RSE) ameliorates atherogenic lipid profile and oxidative stress in
hypercholesterolemia. Methods: After feeding of the RSE to hypercholesterolemic rats for 6 weeks, the levels of plasma
and hepatic to...
Raphanus sativus is a hugely used edible root vegetable. We investigated whether the feeding of the Raphanus sativus hot water extract (RSE) ameliorates atherogenic lipid profile and oxidative stress in hypercholesterolemia. Methods: After feeding of the RSE to hypercholesterolemic rats for 6 weeks, the levels of plasma and hepatic total cholestero...
The aim of the study was to evaluate the effect of Leucas zeylanica against oxidative stress on hepatic tissue. Oxidative stress was induced by exposing hepatic tissue to ethanol and Fentons reagent (H2O2+FeSO4). The effect of oxidative stress on liver also was evaluated by the determination of alanine aminotransferase (ALT), aspartate aminotransf...
Hypercholesterolemia is a clinical situation characterized by the elevated serum cholesterol and associated with the higher risk of cardiovascular disease, hypertension and stroke. Though current therapeutic strategies of hypercholesterolemia meet the present treatment demand but their efficacy is in question as well as the emergence of medicinal r...
ABSTRACT The study was designed to evaluate the effect of oral administration of the polyherbal extract, consisting of Emblica officinalis, Terminalia chebula, Terminalia belerica, Camellia sinensis and Ganoderma lucidium, on the atherogenic lipid profile and cardiac risk in association with fecal cholesterol level and systemic oxidative status in...
Questions
Question (1)
I want to isolate rat genomic DNA, but no reagent kits are available to me.