Mostafa Gouda

Mostafa Gouda
Zhejiang University | ZJU · School of Biosystems Engineering and Food Science

Professor (Assoc./Adjun.)
Awarded the National State Prize in Science and Advanced Sciences, Egypt, 2022/2023

About

109
Publications
22,987
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Introduction
-Recent Interview with Dr. Mostafa Gouda in "Channel 1" official famous TV in Egypt talking about his recent National State Prize in Science and Advanced 2023: https://www.youtube.com/watch?v=y361yx8Id54 - Dr. Gouda official website: https://person.zju.edu.cn/en/mostafagouda Dr. Gouda is Associate Editor in Springer Nature and Frontiers. He got “Talent Introduction I“Talent Introduction International Program” and “Outstanding Special Fund” from Zhejiang University, China.

Publications

Publications (109)
Article
The objective of this study was to evaluate the effects of the natural safety high antimicrobial compounds on egg yolk protein structure and function. Three different concentrations have been evaluated from: trans-cinnamaldehyde, thymol, menthol or vanillin on egg yolk by measuring the antimicrobial activity, Fourier transform infrared (FT-IR), sec...
Article
Microalgae single-cell electrochemical characteristics are playing an important key role in its industrial application and functionality. This study conducted a single-cell electrochemical study to explain the influence mechanism of intracellular phenolic and flavonoid contents of microalgae on its surface electric charge. In the method, four micro...
Article
This study aimed to evaluate the functionality of bioactive terpenes on Spirulina (Arthrospira platensis; AP) and Chlorella (Chlorella vulgaris; CV) biomasses. The two microalgae species were treated with 0.01%, 0.05%, and 0.1% of thymol (THY), trans-cinnamaldehyde (TC), menthol (MEN), and vanillin (VAN). Raman micro-spectroscopy (RMS) was correlat...
Article
The integration between RNA-sequencing and micro-spectroscopic techniques has recently profiled the advanced transcriptomic discoveries on the cellular level. In the current study, by combining the sensation approach (including bio-molecules structural evaluation, high throughput next-generation sequencing (HT-NGS), and confocal Raman microscopy) t...
Article
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The complementary intervention to modulate diabetes mellitus (DM) metabolism has recently brought the global attention, since DM has become among the global burden diseases. Where, several related pathways elevate the production of superoxide in consequences. For example, the flux of glycation-derived end products (AGEs) could lead to the deactivat...
Article
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The combination of nanoemulgel and phytochemistry has resulted in several recent discoveries in the field of topical delivery systems. The present study aimed to prepare nanoemulgel based on turmeric (Curcuma longa) and neem (Azadirachta indica) against microbial infection as topical drug delivery. Olive oil (oil phase), Tween 80 (surfactant), and...
Preprint
Full-text available
The combination of nanoemulgel and phytochemistry has resulted in several recent discoveries in the field of the topical delivery systems. The present study aimed to prepare turmeric (Curcuma longa) and neem (Azadirachta indica) based nanoemulgel against microbial infection as topical drug delivery. Olive oil (oil phase), Tween 80 (surfactant), and...
Preprint
Full-text available
Studying the multi-function bacterial implications on the natural phytochemicals could be among the best solutions for producing clean-label functional juices. This study aimed to develop a high-quality mulberry juice with enhanced antioxidant capacity through fermentation. The juice was fermented using mono- and co-cultures of Lactobacillus casei...
Article
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A variety of events, including infection, traumatic brain damage, neurodegenerative illnesses, and autoimmune disorders, can cause neuroinflammation, a complicated biological reaction in the central nervous system. Glial cells, especially microglia and astrocytes, are activated as part of this complex event, which also results in the production of...
Chapter
One of the most significant developed technologies is the electrochemical sensors to determine the chemical structures of biological cells and their bioactivities. Besides, the new electrochemical techniques for visualizing plant cellular chemical compositions could significantly open the way toward advanced analytical technologies. For instance, e...
Chapter
Raman spectroscopy is a detection method that combines Raman spectroscopy and confocal microanalysis. It can provide chemical fingerprint information of cells, tissues or body fluids, and has the advantages of high sensitivity, non-invasive, no labeling, and little water interference. As a primitive ancient organism, microalgae have evolved to adap...
Chapter
The contents and distribution of catechins and caffeine, strongly reflect the physiology and nutrition of tea. In recent years, spectroscopy technology has been widely applied to the detection of tea content. Based on spectroscopy technology (Fourier transform infrared (FT-IR) spectroscopy and hyperspectral imaging technique) and chemometrics, rapi...
Chapter
Detecting heavy metal–phytochelatin complexes in plants would simplify identification of cultivars with both high tolerance and enrichment abilities for heavy metals. In this study, we introduced a novel approach for the characterization and detection of Cd–PC2 complexes using terahertz spectroscopy, density functional theory, circular dichroism, a...
Chapter
Flavonoids are important secondary metabolites in tea plants, which contribute to the formation of high-quality tea leaves. Their structural variability and similitude increase the difficulty of compound identification. The powerful tool of LC-Q-TOF-MS, combining the separation capabilities of liquid chromatography (LC) with the structural analysis...
Chapter
The development of a rapid and simple method for the determination of theaflavins, thearubicin, and theabrownin quality-related molecules is very beneficial for the study of the fermentation process of black tea. This chapter takes the fermentation process of black tea as an example. Surface-enhanced Raman spectroscopy (SERS) and chemometrics metho...
Chapter
The ongoing process involves the modification and improvement of the stool test that has been validated for the purpose of diagnostic screening of colon cancer (CC). This particular test focuses on the detection of micro(mi)RNAs. The need for this update is primarily driven by the complex nature of fecal density, the variations in stool composition...
Chapter
There are various types of fatty acids, which are essential nutrients for humans and affect the balance of dietary structure, endocrine stability, and the occurrence of metabolic syndrome. The accurate determination of fatty acid content in food, serum, and metabolite samples is of great significance for food quality control, disease monitoring, an...
Article
The recent advances in plant and animal biosystems of hydrocolloids have led scientists to find analytical techniques to explore the scientific principles of these molecules for their functional principles, precursors of essential pathways, and other physical and chemical processes. The current editorial highlights the importance of applying advanc...
Article
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Epigallocatechin gallate (EGCG), the principal catechin in green tea, exhibits diverse therapeutic properties. However, its clinical efficacy is hindered by poor stability and low bioavailability. This study investigated solid particle-in-oil-in-water (S/O/W) emulsions stabilized by whey protein isolate (WPI) and sodium caseinate (NaCas) as carrier...
Preprint
Full-text available
Epigallocatechin gallate (EGCG), the principal catechin in green tea, exhibits diverse therapeutic properties. However, its clinical efficacy is hindered by poor stability and low bioavailability. This study investigated solid particle-in-oil-in-water (S/O/W) emulsions stabilized by whey protein isolate (WPI) and sodium caseinate (NaCas) as carrier...
Article
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Objectives The objective of this research was to investigate the potential anti-inflammatory properties of the Cucurbita pepo fruit. Given the adverse effects associated with long-term use or excessive doses of conventional anti-inflammatory medications, exploring herbal therapies as alternatives has become increasingly important. Methods Various...
Article
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Sechium edule, commonly known as chayote is known for its low glycemic index, high fiber content , and rich nutritional profile, which suggests it may be beneficial for individuals with diabetes. While research specifically examining the impact of chayote on diabetes is limited, this study screened its biological impacts by using different biomarke...
Article
Fuzhuan brick tea (FBT) fungal fermentation is a key factor in achieving its unique dark color, aroma, and taste. Therefore, it is essential to develop a rapid and reliable method that could assess its quality during FBT fermentation process. This study focused on using electronic nose (e-nose) and spectroscopy combination with sensory evaluations...
Chapter
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In green chemistry and new technologies, ultrasound (US) has emerged as one of the most crucial methods. Numerous studies have demonstrated the value of US for treatments of vegetables and fruits. Nonetheless, US has advantages and limitations that need to be clarified for full implementation at an industrial scale, just like with any revolutionary...
Book
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About this book This volume provides food researchers with advanced destructive and non-destructive techniques for measuring the chemical composition, functional bioactivities physicochemical changes, and explaining the functional mechanisms for facilitating the tracking of the functional molecules during the different industrial processes. Chapter...
Article
16 As S. aureus continues to be a harmful foodborne pathogen threatening human health, there is a 17 growing need for rapid technologies for its detection. This study proposed a novel paper biosensor 18 based on a polydiacetylene (PDA) polymer functionalized fibrinogen (Fg) for the detection of S. aureus 19 in food sources. That color and fluoropho...
Article
Crop leaf pixel isolation is a prerequisite step for conducting high-throughput crop phenotype surveys at a large scale. Automated isolation of leaf pixels from RGB imagery has been a challenging task, and the mechanism is not clearly understood. This study proposed a labor-free and automated method for isolating crop leaf pixels from RGB imagery,...
Article
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The past few years have witnessed significant progress in emerging disease detection techniques for accurately and rapidly tracking rice diseases and predicting potential solutions. In this review we focus on image processing techniques using machine learning (ML) and deep learning (DL) models related to multi-scale rice diseases. Furthermore, we s...
Article
Metabolic fluxes (MF) serve as the functional phenotypes of biochemical processes and are crucial to describe the distribution of precursors within metabolic networks. There is a lack of experimental observations for carbon flux towards lipids, which is important for biodiesel generation. Here, the accumulation of lipid, and MF in Tetradesmus obliq...
Article
Full-text available
One of the most significant developed technologies is the use of acoustic waves to determine the chemical structures of biological tissues and their bioactivities. In addition, the use of new acoustic techniques for in vivo visualizing and imaging of animal and plant cellular chemical compositions could significantly help pave the way toward advanc...
Article
Carbon dioxide (CO2) is considered one of the eco-related key factors that negatively affect global climatic change. Also, CO2 can play an important role in the postharvest quality of the agri-products. In this study, the impact of CO2 on the quality of postharvest onions that were stored at 23 °C for 8 weeks was investigated. The weight loss, phen...
Article
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The long‑term application of organic amendments like manure, biochar and biogas slurry can increase phosphorus (P) levels in agricultural soils; however, at present, it’s not clear how this affects the P association with different mobile water‑dispersible colloidal particles (Pcoll). Thus, this study aimed to assess the effects of the long‑term app...
Article
Mobile colloids impact phosphorus (P) binding and transport in agroecosystems. However, their relationship to P lability and their relative importance to P bioavailability is unclear. In soils amended with organic fertilisers, we investigated the effects of nano (NC, 1–20 nm), fine (FC, 20–220 nm), and medium (MC; 220–450 nm) colloids suspended in...
Article
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Plant pathogens continuously impair agricultural yields and food security. Therefore, the dynamic characterization of early pathogen progression is crucial for disease monitoring and presymptomatic diagnosis. Hyperspectral imaging (HSI) has great potential for tracking the dynamics of initial infected sites for presymptomatic diagnosis; however, no...
Article
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The use of functional foods’ phytochemicals in the chemoprevention of different cancer diseases has become one of the hot scientific areas in the clinical nutrition field. For instance, the Khalas palm cultivar (KPC; Phoenix dactylifera) is one of the natural sustainable resources that have high bioactivity and functionality. This study aimed to in...
Article
Full-text available
The use of functional foods’ phytochemicals in the chemoprevention of different cancer diseases has become one of the hot scientific areas in the clinical nutrition field. For instance, the Khalas palm cultivar (KPC; Phoenix dactylifera) is one of the natural sustainable resources that have high bioactivity and functionality. This study aimed to in...
Chapter
Full-text available
Pomegranate fruit (Pg) has a long history for promoting health and well-being and curing multiple diseases in many geographic regions of the world. Its large number of bioactive phytochemicals have proven useful in treating chronic non-communicable diseases such as cardiovascular and neurodegenerative disorders, cancer, osteoarthritis, and erectile...
Article
Developing a reliable and convenient method for monitoring the quality of black tea during fermentation could lead to a significant improvement in fermentation process. This work presented a rapid method based on surface-enhanced Raman spectroscopy (SERS) technology and chemometrics to determine the optimal fermentation stage and monitor the change...
Article
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Inhibin is a molecule that belongs to peptide hormones and is excreted through pituitary gonadotropins stimulation action on the granulosa cells of the ovaries. However, the differential regulation of inhibin and follicle-stimulating hormone (FSH) on granulosa cell tumor growth in mice inhibin-deficient females is not yet well understood. The objec...
Article
Full-text available
Inhibin is a molecule that belongs to peptide hormones and that excreted through pituitary gonadotropins stimulation action on the granulosa cells of the ovaries. However, the differential regulation of inhibin and follicle-stimulating hormone (FSH) on granulosa cell tumor growth in mice inhibin-deficient females is not yet well understood. The obj...
Article
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Aquaponics is an innovative, smart, and sustainable agricultural technology that integrates aquaculture (farming of fish) with hydroponics in growing vegetable crops symbiotically. The correct implementation of aquaponics helps in providing healthy organic foods with low consumption of water and chemical fertilizers. Numerous research attempts have...
Article
Full-text available
Aquaponics is an innovative, smart, and sustainable agricultural technology that integrates aquaculture (farming of fish) with hydroponics in growing vegetable crops symbiotically. The correct implementation of aquaponics helps in providing healthy organic foods with low consumption of water and chemical fertilizers. Numerous research attempts have...
Article
Full-text available
Aquaponics is an innovative, smart, and sustainable agricultural technology that integrates aquaculture (farming of fish) with hydroponics in growing vegetable crops symbiotical-ly. The correct implementation of aquaponics helps in providing healthy organic foods with low consumption of water and chemical fertilizers. Numerous research attempts hav...
Article
Full-text available
Proanthocyanidins (PAs) are considered as effective natural by-product and bioactive an-tioxidants. However, few studies were focused on their mode of action pathways. In this study, reactive oxygen species (ROS), oxidative stress indices, real-time PCR, western blotting, confocal microscopy, and molecular docking were used to investigate the prote...
Article
Oxidative stress of aquatic microorganisms under heavy metal stress is closely reflected by metabolite changes in cells but it is very difficult to study due to the fast metabolism process and severe in-situ measurements hurdle. Herein, the oxidative stress of cadmium on Euglena gracilis was systematically studied through multi-combined techniques....
Article
Full-text available
Integrating physical and chemical technologies for the characterization and modification of plants and animal tissues has been used for several decades to improve their detection potency and quality [1]. Scientists have been exploring the scientific basis and mechanism of action of the chemical constituents in biological tissues [1,2]. Additionally...
Article
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Peaches are grown in many Egyptian orchards for local and global fresh market sales. The interior fruit tissue breakdown (IFTB), often resulting in decayed peaches, is a severe problem during marketing. Therefore, to minimize FTB of peaches, in this study, gum arabic (GA) and polyvi-nylpyrrolidone (PVP) were mixed with different concentrations of s...
Article
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Noble metal nanoparticles (NMNPs) are viable alternative green sources compared to the chemical available methods in several approach like textile industries. The biological synthesis of Platinum nanoparticles (PtNPs), as a strong photocatalytic agent, has proved as more effective and safer method. In this study, PtNPs were synthesized at four diff...
Article
Full-text available
There is a global interest in the novel consumption, nutritional trends, and the market of new prebiotic sources and their potential functional impacts. Commercially available nutritional supplements based on microalgae that are approved to be edible by FDA, like Arthrospira platensis (Cyanobacteria) and Chlorella vulgaris (Chlorophyta) become wide...
Cover Page
Full-text available
Dear Colleagues, Welcome to submit your research works to our recent Special issue entitled "Ultrasound with Acoustic-Based Sensors and Biosensors for the Chemical Composition of Plant and Animal Tissues" in Molecules SCI journal with Impact Factor: 4.412 (2020) and 5-Year Impact Factor: 4.588 (2020): https://www.mdpi.com/journal/molecules/special_...
Chapter
Full-text available
Pomegranate fruit (Pg) has a long history for promoting health and well-being and curing multiple diseases in many geographic regions of the world. Its large number of bioactive phytochemicals have proven useful in treating chronic non-communicable diseases such as cardiovascular and neurodegenerative disorders, cancer, osteoarthritis, and erectile...
Article
Full-text available
In the aquaponic system, plant nutrients bioavailable from fish excreta are not sufficient for optimal plant growth. Accurate and timely monitoring of the plant's nutrient status grown in aquaponics is a challenge in order to maintain the balance and sustainability of the system. This study aimed to integrate color imaging and deep convolutional ne...
Article
Agro-wastes contribute major social, economic, and environmental challenges for food production and circular economy systems. The current increasing demand for clean label food production and use of natural bioactive compounds could turn these challenges into opportunities providing avenues for proper utilization of agro-wastes to produce valuable...
Article
Plants synthesize phytochelatins to chelate in vivo toxic heavy metal ions and produce nontoxic complexes for tolerating the stress. Detection of the complexes would simplify the identification of high phytoremediation cultivars, as well as assessment of plant food for safe consumption. Thus, a confocal Raman spectroscopy combined with density func...
Chapter
Novel protein sources require a comprehensive risk assessment as directed in EC regulation no. 258/97. Potential allergenic response from the ingestion or contact with novel proteins is a significant public health concern. Therefore, risk assessment of novel proteins is key to creating awareness and to reducing the risk of allergic reactions. The d...
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Schisandrin A (SCH) is a natural bioactive phytonutrient that belongs to the lignan deriva- tives found in Schisandra chinensis fruit. This study aims to investigate the impact of SCH on promoting neural progenitor cell (NPC) regeneration for avoiding stroke ischemic injury. The pro- moting effect of SCH on NPCs was evaluated by photothrombotic mod...
Article
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Poly (butylene succinate) (PBS) is one of the most common biodegradable plastic polymers that has recently been used in the green environmental field. Enhancement of physicochemical characteristics of these polymers by using plant-based materials like Baobab (Adansonia digitata) will improve its industrial application. This study evaluated Baobab (...
Article
Packing carrier is a key factor for moving bed biofilm reactors (MBBRs) treating ammonia polluted wastewater such as in mariculture aquaculture but lacks sufficient research. In this study, a new type of biocarrier, Saddle-Chips (SC), was applied for treating mariculture wastewater (30‰ salinity) and compared with commonly used Kaldnes-5 (K5-biocar...
Article
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Background: A Serine/Threonine Kinase 3 (AKT3) is a protein coding gene that associated with several cattle immune diseases include the different tumors and cancers. The objective of this study was to investigate the differences in structures and functions of AKT3 of cow and buffalo cattle. Methods: The sequence differences of gene–coding sequence...
Article
Full-text available
Phytochelatins are plants' small metal-binding peptides which chelate internal heavy metals to form nontoxic complexes. Detecting the complexes in plants would simplify identification of cultivars with both high tolerance and enrichment capabilities for heavy metals which represent phytoextraction performance. Thus, a terahertz spectroscopy combine...
Article
Full-text available
Background: Mastitis is one of the major diseases causing economic loss to the dairy industry by reducing the quantity and quality of milk. Thus, the objective of this scientific study was to find new biomarkers based on genes for the early prediction before its severity. Methods: In the present study, advanced bioinformatics including hierarchi...
Article
Full-text available
Using ultrasound (US) in proanthocyanidins (PAs) extraction has become one of the important emerging technologies. It could be the next generation for studying the US mechnophore impact on the bioactive compound's functionality. The objective of this study was to demonstrate the potential of US treatment on PAs extracted from kiwifruit (Actinidia c...
Article
The toxicity impact of herbicides on crop, animals, and human are big problems global wide. The rapid and non-invasive ways for assessing herbicide-responsible effects on crop growth regarding types and levels still remain unexplored. In this study, visible/near infrared hyperspectral imaging (Vis/NIR HSI) coupled with SCNN was used to reveal the d...
Article
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Using nature multi-function phytochemicals could be one of the best solutions for clean label production. In this study, dairy ice creams were prepared containing 14% egg yolk and 0.1% of thymol (THY), trans-cinnamaldehyde (TC), menthol (MEN), or vanillin (VAN). Then, the physical, chemical, and structural characteristics were evaluated. Magnetic r...
Article
Innovative removal of toxic nitrite and ammonia is one of the key approaches for efficient aquaculture biotechnology. This study suggests a fast removal technique of high-levels of nitrite and ammonia using recirculating aquaculture wastewater at 30‰ salinity. Four lab-scale moving bed biofilm reactors (MBBRs; R1, R2, R3, and R4) were operated in p...
Article
Full-text available
Global interest of new consumption, nutrition trends, and market for dietary phytochemical functional supplements have greatly increased over recent decades. In which, commercially available food supplements based on microalgae such as Spirulina (Cyanobacteria) are becoming increasingly popular. Microalgae are rich in important nutritional phytoche...
Article
Abstract: Cancer is a global multifactorial disease consisting of over 200 types of cancers. It is well recognized that primary prevention is an effective way to fight cancers by using natural polyphenolic anticancer foods, vegetables, and fruits, avoiding exposure to the carcinogenic environment, smoking cessation, and through lifestyle modificati...