Morteza Jarrahi

Semnan University of Medical Sciences | SUMS · School of Medicine

Background: Few past studies have indicated antispasmodic and anti-oxidative effects of some species of Rubiaceae. Objectives: This studyaimedto investigate the effect of hydroalcoholic extract of Rubia tinctorum L. (madder) rootonthe rat-isolated aorta and possible protective effects against the damage caused by hyperglycemic environment. Methods:...

Background Few studies have evaluated the effect of Rosa damascena (R. damascena) on uterine smooth muscle contraction and dysmenorrhea; but, their ‎results were inconsistent. Objectives The aim of the study was to consider the effect of alcoholic extract of R. damascena flower on uterine smooth muscle contraction amplitude, duration, and frequenc...

Objectives: The aim of this study was to investigate the effects of nutritional saffron (Crocus sativus L.) stigma hydroalcoholic extract on blood pressure (BP) and histology of the aorta in normotensive and hypertensive rats. Materials and methods: Saffron (200 mg/kg/day) was given orally for 5 weeks to normotensive and hypertensive rats. Hyper...

Assessment of the ability of rat to balance by rotarod apparatus (ROTA) is frequently used as a measure of impaired motor system function. Most of these methods have some disadvantages, such as failing to sense motor coordination rather than endurance and as the sensitivity of the method is low, more animals are needed to obtain statistically signi...

Background and Objective: The kidney has a key role in homeostatic regulation. Vascular endothelial growth factor (VEGF) is essential regulator of stimulatory and inhibitory processes for neonatal, postnatal endothelial cell differentiation. This study was done to determine the effect of maternal swimming during pregnancy on VEGF level of kidney in...

Garlic (Allium Sativum) has many sulfur containing active principles mostly in the form of cysteine derivations such as S-alkil cysteine sulfoxides which decay into a variety thiosulfinates and poly sulfides by the act of an enzyme allinase on extraction. Decomposed yield are volatile and present in the oils of garlic. They poses hypocholesterolaem...

In this investigation, the effect of Matricaria chamomilla extract on linear incisional wound healing was studied. Thirty male Wistar rats were subjected to a linear 3 cm incision made over the skin of the back. The animals were randomly divided into three experimental groups, as control, olive oil, and treatment. Control group did not receive any...

Background: There are some information about antimicrobial and anti-inflammatory effect of Matricaria chamomilla flower oil extract, but there isn't any information about its effect on linear incisional wound healing. Objective: In this investigation, the effect of Matricaria chamomilla flower oil extract on linear incisional wound healing was stud...

Previous investigation has shown that Thymus Vulgaris (TV) modulates pain. The aim of this work was to examine the role of TV on acute and chronic pain and compares its effect with dexamethasone (DEX) and stress (ST) by using hot plate, tail flick and formalin tests in mice. In this study male albino mice (25-30 g.) in 21 groups (n=147) were used....

Previous studies conducted on the anti-inflammatory, antimicrobial and antioxidant effects of Matricaria chamomilla (chamomile) extract led us to study the effect of topical chamomile extract on burn wound healing in albino rats. Thirty male albino rats (250-300 g) were randomly divided into three groups, as control, vehicle, and treatment. Second-...

Background: Portulaca oleracea (PO) overgrows in different parts of Iran. In previous studies, a 10% hydroalcoholic extract of the PO aerial parts (leaf and stem) showed anticeptive and anticonvulsive activity in rats. Objective: This study was designed to evaluate anxielytic effects in different doses of the aqueous decoction extracts of PO seed....

Melissa officinalis(MO) is a herb which grows in different parts of Iran. In previous studies, it was reported that 10% ethanolic extract of the aerial parts of MO, i.e. leaf and stem, could bring about antinociceptive, anticonvulsive, and sedative effects on rats. This study was designed to evaluate anxiolytic effects of different doses of the aqu...

Background: Since use of synthetic drugs for relief of pain has many side effects, today medical plants are becoming more prominent as substitute therapeutic agents. Previous findings indicate that Coriandrum sativum (CS) modulates pain in both animal and human. Objective: The present work investigated the effects of CS seed on acute pain using hot...

Portulaca oleracea (PO) overgrows in the different parts of Iran. In previous studies, ethanolic extracts of PO showed antinociceptive activity, sedative in animal. This study was designed to evaluate anxiolytic effects in different doses of the aqueous decoction extracts of PO. In this study, fourty male mice (25-30 g) were used in elevated plus m...

Garlic extract is gaining increasing acceptance as an antimicrobial and anti-inflammatory agent and as a folk remedy on wound healing. We studied the effect of crushed garlic extract on wound healing in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups,...

In this study, the effect of phenytoin cream on linear incisional wound healing was investigated. Thirty male Wistar rats were subjected to a linear 3cm incision made over the skin of the back. The animals were randomly divided into 3 experimental, control, cold cream and treatment groups. Control group did not receive any drug or cold cream. Cold...

A few studies have shown that stress and glucocorticoids probably interfere in pain control. The aim of this study was to investigate the role of dexamethasone(Dex) as a glucocorticoid receptor agonist on acute and chronic pain in formalin test in mice. In this study male albino mice(n=60) in 6 groups(25-30gr) were used. Dex ( 0.5, 1 and 2mg/kg) wa...