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April 2008 - April 2015
Publications
Publications (83)
Introduction
Fusionless surgical techniques are increasingly used to treat patients with early-onset and juvenile neuromuscular scoliosis (NMS) to correct and stabilize the scoliotic curves while preserving natural growth. This study aimed to evaluate clinical and radiological outcomes two years after minimally invasive surgery using a commercially...
BACKGROUND
Atypical lumbar disc herniations, such as migratory extreme lateral and intradural herniations, can mimic malignancy on imaging, complicating diagnosis and treatment. These herniations can involve unusual locations, such as the retroperitoneal or presacral area. Migratory herniations, in particular, can appear similar to peripheral nerve...
Introduction
Percutaneous screw fixation is a widely used treatment for posterior pelvic ring injuries. Transiliac-transsacral screw fixation has demonstrated superior biomechanical properties over bilateral sacroiliac screws, particularly in the minimally displaced bilateral sacral fractures. Screw placement under fluoroscopic control is still com...
This study aimed to evaluate the safety and efficacy of a novel Poly-Ether-Ether-Ketone (PEEK) expandable vertebral body replacement (VBR) for anterior cervico-thoracic vertebral column reconstruction in patients with metastatic, traumatic, or degenerative diseases. Radiographic and clinical outcomes, as well as complication rates, were analyzed in...
Introduction
Traumatic thoracolumbar burst fractures are the most common spinal injuries and the proper treatment is controversial. In central Europe in particular, these fractures are often treated with minimally invasive anterior-posterior reduction and fusion, whereas a conservative approach is preferred in the USA. Independent of the treatment...
Assessing the diagnostic performance and supplementary value of whole-body computed tomography scout view (SV) images in the detection of thoracolumbar spine injuries in early resuscitation phase and identifying frequent image quality confounders.
In this retrospective database analysis at a tertiary emergency center, three blinded senior experts i...
Introduction
Autism spectrum disorder (ASD) is characterized by deficits in social communication, repetitive behaviors, and can be accompanied by a spectrum of psychiatric symptoms, such as schizophrenia and catatonia. Rarely, these symptoms, if left untreated, can result in spinal deformities.
Research question and case description
This case repo...
La scoliose est une déformation complexe, tridimensionnelle de la colonne vertébrale, du thorax et du tronc. Le formes secondaires, comme celles dues à des maladies neuromusculaires, syndromiques ou congénitales, représentent environ 20% des scolioses. Environ 80% sont idiopathiques, dont la cause est à ce jour inconnue.
Eine Skoliose ist eine komplexe, dreidimensionale Deformität der Wirbelsäule, des Thorax und des Rumpfes. Sekundäre Skolioseformen, wie bei neuromuskulären Erkrankungen, syndromal oder kongenital bedingt, zählen ca. 20% aller Skoliosen. Rund 80% sind idiopathisch – mit bislang unbekannter Ursache.
Introduction
Atlas ring fractures, which account for 1.3% of all spinal fractures, are predominantly managed conservatively. However, in certain cases, surgical treatment may be necessary depending on the type of fracture, degree of comminution, fracture location, and associated ligamentous injuries. Surgical stabilization frequently results in a p...
Study design:
A single-center validation study.
Objective:
To translate and cross-culturally adapt the AO Spine PROST (Patient Reported Outcome Spine Trauma) into German, and to test its psychometric properties among German-speaking Swiss spine trauma patients.
Methods:
Patients were recruited from a level-1 Swiss trauma center. Next to the AO...
Purpose
The aim of this study was to assess safety and efficacy of vertebral body stenting (VBS) by analyzing (1) radiographic outcome, (2) clinical outcome, and (3) perioperative complications in patients with vertebral compression fractures treated with VBS at minimum 6-month follow-up.
Methods
In this retrospective cohort study, 78 patients (61...
Background
Bone marrow mesenchymal stromal cells (BMSCs) are promising for therapeutic use in cartilage repair, because of their capacity to differentiate into chondrocytes. Often, in vitro differentiation protocols employ the use of high amount of glucose, which does not reflect cartilage physiology. For this reason, we investigated how different...
For revision hip arthroplasty, both cemented and cementless techniques have been described for implantation of modular and non-modular implants. Although many articles have been published on non-modular prosthesis, there is a dearth of data on cementless, modular revision arthroplasty in young patients. This study aims to analyze the complication r...
Background and Purpose:
Fractures of the thoracolumbar spine (TLS) are common in polytrauma. Prompt detection of spinal injuries is essential in the early resuscitation phase. Whole-body CT (WBCT) is used as standard diagnostic tool for spinal screening. Each WBCT starts with a CT scout view (SV) to prescribe and display locations of CT slices. Apa...
Study design
This is a retrospective cohort study.
Objectives
This study aims to determine the proportional incidence, clinical characteristics, treatment patterns with complications and changes in treatment of vertebral fractures over 10 years at a Swiss university hospital.
Methods
A retrospective cohort study was performed. All patients with a...
Background and purpose
To assess the feasibility of postoperative stereotactic body radiation therapy (SBRT) for patients with hybrid implants consisting of carbon fiber reinforced polyetheretherketone and titanium (CFP-T) using CyberKnife.
Materials and methods
All essential steps within a radiation therapy (RT) workflow were evaluated. First, th...
Introduction
Summer alpine sports, including mountain biking, hiking and airborne pursuits, have experienced a recent surge in popularity. Accordingly, trauma associated with these activities has increased. There is a scarcity of literature exploring clinical aspects surrounding injuries. Specifically, no single article provides a general overview,...
Background:
The current standard of care for intervertebral disc (IVD) herniation, surgical discectomy, does not repair annulus fibrosus (AF) defects, which is partly due to the lack of effective methods to do so and is why new repair strategies are widely investigated and tested preclinically. There is a need to develop a standardized IVD injury...
•Gender trends in authorship showed an increase in female authors from 1976 to 2020.•In 2020, Europe had the highest and Asia the lowest proportion of female authors.•The Netherlands had the highest proportion of women and Japan the lowest.
Background: Surgical treatment for erosive pyogenic spondylodiscitis of the lumbar spine is challenging as, following debridement of the intervertebral and bony abscess, a large and irregular defect is created. Sufficient defect reconstruction with conventional implants using a posterior approach is often impossible. Therefore, we developed the “Ce...
Background and purpose
To assess the feasibility of postoperative stereotactic body radiation therapy (SBRT) for patients with hybrid implants consisting of carbon fiber reinforced polyetheretherketone and titanium (CFP-T) using CyberKnife.
Materials and methods
All essential steps within a radiation therapy (RT) workflow were evaluated. First, the...
Scoliosis is a three-dimensional (3D) structural deformity of the spine with a radiological lateral Cobb angle of ≥ 10°. Several classification systems exist, dividing different types regarding the age of onset or the type of etiology. The minority of cases are secondary to congenital, syndromic of neuromosucular diseases. Most of the cases are cla...
An atypical course of the vertebral artery can be medically relevant in displaced Hangman fractures, especially if the artery course runs within the fracture gap of the C2 isthmus. During surgical reduction, the artery can be occluded inside the fracture, potentially leading to ischemic conditions of the brain. The aim of this study was to report t...
Study design:
Bibliometric review.
Objective:
This study aims to understand the worldwide research productivity trends in spine-related research over the past five decades.
Summary of background data:
Research productivity in the field of spine surgery has increased tremendously over the past decades. However, knowledge regarding the detailed...
Background
The economic burden of vertebral compression fractures (VCF) caused by osteoporosis was estimated at 37 billion euros in the European Union in 2010. In addition, the incidence is expected to increase by 25% in 2025. The recommendations for the therapy of VCFs (conservative treatment versus cement augmentation procedures) are controversia...
Background: The economic burden of vertebral compression fractures (VCF) caused by osteoporosis was estimated at 37 billion euros in the European Union in 2010. In addition, the incidence is expected to increase by 25% in 2025. The recommendations for the therapy of VCFs (conservative treatment versus cement augmentation procedures) are controversi...
Compartment syndrome of the upper and the lower extremities is a well-known entity in emergency medicine and traumatology. However, compartment syndrome of the paraspinal musculature is a very rare cause of acute back pain and may be missed at presentation despite its clinical importance. Therefore, we present a case of paraspinal compartment syndr...
PurposeTo evaluate whether a new PEEK vertebral body replacement can maintain the sagittal alignment as an anterior column reconstruction device in thoracic and lumbar spinal defects due to trauma or tumor.Methods
Retrospective review of 48 patients who underwent a corpectomy between T5 and L5 due to trauma or tumor and were stabilized with the new...
Die genetische Ursache der meisten Skoliosen ist unbestritten, wenn auch die genauen Erbgänge noch nicht entschlüsselt sind. Das Korsett ist weiterhin das Mittel der Wahl zur konservativen Therapie mittelgradiger Skoliosen in Kombination mit Physiotherapie. Für die Zukunft zeichnen sich neue operative Verfahren ab.
Fragestellung: Durch die Verwendung von Metallimplantaten in der Tumor-Wirbelsäulenchirurgie entstehen Artefakte in Planungs-CTs für die postoperative Bestrahlung, die die CT-Bildqualität beeinträchtigen und damit die Konturierung und Dosisberechnung in der Strahlentherapie beeinflussen. Implantate aus kohlefaserverstärktem Poly-Ether-Ether-Keton (...
Abstract
AIMS:
We evaluated a large database with mechanical failure of a single uncemented modular femoral component, used in revision hip arthroplasty, as the end point and compared them to a control group treated with the same implant. Patient- and implant-specific risk factors for implant failure were analyzed.
METHODS:
All cases of a fractured...
Introduction:
Spinopelvic dissociation is a rare type of injury which occurs in approximately 2.9% of pelvic disruptions and correlates with high-energy trauma.The purpose of this study was to systematically evaluate the incidence, demographics, treatment, clinical outcome, and complication rate associated with these injuries.
Methods:
A literat...
The aim of this study was to assess the performance of a new vacuum plasma sprayed (VPS) titanium-coated carbon/polyetheretherketone (PEEK) cage under first use clinical conditions. Forty-two patients who underwent a one or two segment transforaminal lumbar interbody fusion (TLIF) procedure with a new Ca/PEEK composite cage between 2012 and 2016 we...
Background:
Airborne sports have become more popular in recent years. The number of accidents has increased linearly as athletes take increasingly greater risks to experience the adventurous spirit of this kind of sports.
Aim:
To investigate the variety of injuries in airborne sport accidents, as well as which acute treatment these patients rece...
Background: Rhabdomyolysis is a potentially fatal condition that can be triggered by a variety of inciting events, including excessive muscular exertion.
The purpose of this study was to investigate the causes of creatine kinase elevation (CK≥1,000U/L) to determine what percentage result from exRML, the aetiology and kinetics of CK levels, as well...
Carbon fibre reinforced polyether ether ketone (CFR-PEEK) is a suitable material to replace metal implants in orthopaedic surgery. The radiolucency of CFR-PEEK allows an optimal visualisation of the bone and soft tissue structures. We aimed to assess the performance and radiological and clinical outcomes of anterior cervical discectomy and fusion (...
Objective Sheep are used as a large animal model for intervertebral disc research. However, for the ovine ventral surgical approach to the cervical disc, limited descriptions exist. We, therefore, give a detailed in vivo anatomical description of this approach in sheep for the use in intervertebral disc regeneration and degeneration models to incre...
Carbon fibre reinforced polyetheretherketone (CFR-PEEK) is a suitable material to replace metal implants in orthopaedic surgery. The radiolucency allows optimal visualization of bone and soft tissue. We aimed to assess performance and radiological and clinical outcomes of anterior cervical discectomy and fusion (ACDF) with CFR-PEEK anterior cervica...
Purpose
The purpose of this study was to investigate the type and severity of spinal injury in airborne sports, as well as patients demographics in this unique set of athletes. Paragliding is one of the most popular airborne sports in Switzerland, which thought to be no less dangerous with a high potential for spinal injury. Few studies on spinal c...
The aim of this study was to assess the performance of a new vacuum plasma sprayed (VPS) titanium-coated carbon/polyetheretherketone (PEEK) cage under first use clinical conditions. Forty-two patients who underwent a one or two segment transforaminal lumbar interbody fusion (TLIF) procedure with a new Ca/PEEK composite cage between 2012 and 2016 we...
We present a rare case of traumatic bilateral asymmetric hip dislocation with pelvic fractures and a traumatic diaphragmatic hernia. A 53-year-old machinist was transferred to our emergency department with the suspicion of a bilateral hip dislocation after he was trapped between an elevator and the roof. Immediate closed reduction of the hips was n...
We present a rare case of traumatic bilateral asymmetric hip dislocation with pelvic fractures and a traumatic diaphragmatic hernia. A 53-year-old machinist was transferred to our emergency department with the suspicion of a bilateral hip dislocation after he was trapped between an elevator and the roof. Immediate closed reduction of the hips was n...
Background:
Piercings are placed at different body sites often invisible to medical staff. They may cause additional injuries in trauma and emergency surgery by electro-cautery.
Objective:
To clarify whether electro-coagulation will have a direct damaging effect to the skin around a pierced skin area.
Methods:
Metallic piercings were fixed at...
Study Design
Retrospective case series.
Objective
Short posterior stabilization with vertebroplasty is one treatment option for thoracolumbar burst fractures (AO A3). Whether it avoids progression in segmental kyphosis, especially after implant removal, is unclear. In a retrospective case-control study, its stability and the effect on intervertebr...
Fragestellung: Aufgrund stark zunehmender primär Eingriffe der Wirbelsäulenchirurgie im letzten Jahrzehnt ist eine Steigerung der Revisionsoperationen zu verzeichnen. Vor besondere Herausforderungen stellt den Chirurgen die Sicherung von Implantatlockerungen, Pseudarthrosenbildungen und implantatassoziierten Infekten - insbesondere low-grade Infekt...
Background: The clinical presentation of spondylsodiscitis/spondylitis are manifold. This commonly leads to a period of several months from initial symptoms to final diagnosis. A standardised treatment is difficult. The purpose of this study is to investigate the treatment carried out for patients with spondylodiscitis or spondylitis to develop an...
Infiltration procedures are a common treatment of lumbar radiculopathy. There is a wide variety of infiltration techniques without an established gold standard. Therefore, we compared the effectiveness of CT-guided transforaminal infiltrations versus anatomical landmark-guided transforaminal infiltrations at the lower lumbar spine in case of acute...
Background and purpose — Due to the relative lack of reports on the medium- to long-term clinical and radiographic results of modular femoral cementless revision, we conducted this study to evaluate the medium- to long-term results of uncemented femoral stem revisions using the modular MRP-TITAN stem with distal diaphyseal fixation in a consecutive...
Background Since the 1990s, balloon kyphoplasty has been proven as an effective method of treating patients with painful vertebral compression fractures (VCF). However, due to the low viscosity of the PMMA cement uncontrollable cement leakage with corresponding risks is often the focus of discussions on this procedure. The Radiofrequency Kyphoplast...
Fragestellung: Protheseninfektionen (PJI) stellen eine schwerwiegende Komplikation nach künstlichem Gelenkersatz dar. In der Literatur werden vornehmlich monomikrobielle Infektionen als ursächlich für eine PJI angegeben. Mit der stetig steigenden Lebenserwartung und der zunehmenden Zahl immungeschwächter Patienten, ist im Allgemeinen mit einer anst...
Background
We present a descriptive and retrospective analysis of revision total hip arthroplasties (THA) using the MRP-TITAN stem (Peter Brehm, Weisendorf, GER) with distal diaphyseal fixation and metaphyseal defect augmentation. Our hypothesis was that the metaphyseal defect augmentation (Impaction Bone Grafting) improves the stem survival.
Meth...
Introduction
Cervical disk replacement seems to be a promising alternative to anterior cervical fusion. However, there is still lack of information about the generation of wear particles and local reaction to these particles in human cervical spine under in vivo conditions. The authors report clinical outcome and histological findings of three revi...
An evaluation of treatment protocols was used to expand the documentation of efficacy and safety of radiofrequency kyphoplasty (RFK). Additionally, a comparison of this new and innovative procedure with conservative treatment was carried out. Patients,
Patients with painful osteoporotic vertebral fractures according to the common findings in an ort...
The aim of the evaluation of treatment protocols was an extension of the documentation regarding efficacy, duration of action and safety of balloon kyphoplasty. In addition, the data analysis should be used to clarify whether differences arise concerning the treatment success, depending on the number and/or position of the augmented vertebral bodie...
Introduction
Cervical disk replacement seems to be a promising alternative to anterior cervical fusion. However, there is still lack of information about the generation of wear particles and local reaction to these particles in human cervical spine under in vivo conditions. The authors report clinical outcome and histological findings of three revi...
Introduction: We present the results of a prospective controlled study
of the uncemented modular revision prostheses “MRP-TITAN” with a
distal diaphyseal anchorage with and without metaphyseal bone stock
augmentation.
Materials and methods: In the context of a prospective multicenter
study 243 cementless stem revisions in matched patients using the...
Traditional surgical methods for the reconstruction of cartilage defects rely on the transplantation of autologous and allogenous tissues. The disadvantages of these techniques are the limited availability of suitable tissues and the donor site morbidity of transplants. In addition, in cultured chondrocytes, the dedifferentiation of cells seems una...
