Monique van Dijk

Monique van Dijk
Erasmus MC | Erasmus MC · Department of Pediatric Surgery and Internal Medicine

Professor in Nursing Science

About

329
Publications
67,445
Reads
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8,058
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Introduction
Monique van Dijk currently works as a Professor in Nursing Science at the Department of Internal Medicine and Pediatric Surgery, Erasmus MC. Monique does research in pain assessment in preverbal and nonverba patients, clinimetrics, nursing topics, patient safety and trauma. She and her group currently evaluate the effect of 100% single rooms in the adult hospital with a focus on patient safety (e.g. fall incidents), quality of care (e.g. sleep quality, perceived quality of care by patients) and the impact on health care professionals.
Additional affiliations
June 2017 - present
Erasmus MC
Position
  • Professor
November 2000 - present
Erasmus MC
Position
  • Associate Professor Quality of Care

Publications

Publications (329)
Article
Full-text available
Background Central automated unit dose dispensing (cADD) with barcode-assisted medication administration (BCMA) has been shown to reduce medication administration errors (MAEs). Little is known about the cost-effectiveness of this intervention. Objective To estimate the cost-effectiveness of cADD with BCMA compared to usual care. Methods An econo...
Article
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Objectives: Intravenous admixture preparation errors (IAPEs) may lead to patient harm. The primary aim of this study was to assess the effect of a pharmacy-based centralized intravenous admixture service (CIVAS) on IAPEs. Methods: We conducted a before-and-after study in 3 clinical wards before CIVAS implementation and in the CIVAS unit 18 month...
Article
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Objectives Children's pain, undersedation, iatrogenic withdrawal syndrome and delirium often have overlapping symptoms, which makes it difficult to decide why a child in the PICU is not comfortable. Validated assessment tools for these conditions are available, but regular assessment with multiple instruments may be too time-consuming. Therefore, w...
Article
Background: Non-pharmacologic interventions might be effective to reduce the incidence of delirium in pediatric intensive care units (PICU). Aim: To explore expert opinions and generate informed consensus decisions regarding the content of a non-pharmacologic delirium bundle to manage delirium in PICU patients. Study design: A two-round online...
Article
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Objective To evaluate possible negative long-term effects of neonatal exposure to pain, opioids and anesthetics in children and adolescents. Study Design We studied five unique groups of children recruited from well-documented neonatal cohorts with a history of neonatal exposure to pain, opioids or anesthetics at different points along the continu...
Article
Background Pharmacological interventions still form the mainstay of the management of pain, anxiety, sleep problems and discomfort. In Europe, an estimated 100 million people use complementary non-pharmacological interventions (NPIs) for these conditions. In their pre-registration education, nurses do not generally learn about the various types of...
Article
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Spontaneous closure of the ductus arteriosus depends on gestational age (GA) and might be delayed in preterm infants, resulting in patent ductus arteriosus (PDA). Ibuprofen can be administered to enhance closure, but the exposure‐response relationship between ibuprofen and the closure of PDA remains uncertain. We investigated the influence of patie...
Article
Introduction In Europe, more and more people use complementary therapies (CT) for the management of pain, anxiety, sleep problems and discomfort. However, nursing students are generally not taught about CT. Furthermore, nurses are not taught how to communicate about patients’ complementary health seeking behavior, nor how to integrate CT in their n...
Article
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Background Quality of life in cancer patients might be affected by chemotherapy-induced toxicity. Especially in patients with pancreatic ductal adenocarcinoma (PDAC), with a short life expectancy, fear of poor quality of life is often a reason for both patients and medical oncologists to refrain from further treatment. In this study, we investigate...
Article
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Background: Immobility during hospital stay is associated with muscle weakness, delirium, and delayed neurocognitive recovery. Early mobilization of critically ill adults improves their physical functioning and shortens the duration of mechanical ventilation. However, comparable research in children is lacking. Aims: To determine the effects of...
Article
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Children treated in a pediatric intensive care unit (PICU) are at risk of distress and pain. This study investigated if aromatherapy massage can reduce children's distress and improve comfort. This observational before‐after study was performed in a 22‐bed PICU in Cape Town, South Africa. The aromatherapy massage consisted of soft massaging using t...
Article
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Aims and objectives: To identify the prevalence and determinants of medication administration errors (MAEs). Background: Insight into determinants of MAEs is necessary to identify interventions to prevent MAEs. Design: A prospective observational study in two Dutch hospitals, a university and teaching hospital. Methods: Data were collected b...
Article
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Objectives: Placebo effects, beneficial treatment outcomes due to non-active treatment components, play an important role in the overall treatment response. To facilitate these beneficial effects it is important to explore the perspectives of health care professionals (HCPs) on the integration of placebo effects in clinical care. Three themes were...
Article
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Background: Recipients of an organ transplantation face a number of challenges and often need to change their health behaviour. Good self-management skills are essential for optimal clinical outcomes. However, few interventions are available to support post-transplant self-management. To fill this gap, we developed a self-management support interv...
Article
Full-text available
Background Medication administration errors (MAEs) occur frequently in hospitals and may compromise patient safety. Preventive strategies are needed to reduce the risk of MAEs. The primary aim of this study was to assess the effect of central automated unit dose dispensing (ADD) with barcode-assisted medication administration (BCMA) on the prevalen...
Article
Full-text available
Purpose Parents of infants admitted to a neonatal intensive care unit (NICU) experience additional stress due to restrictions on their presence and visits by other family members during the COVID-19 pandemic. Our study aims to describe how this impacted parents and how NICU staff could support them. Design and methods This was a cross-sectional st...
Article
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Background Intravenous admixture preparation errors (IAPEs) may lead to patient harm. Insight into the prevalence as well as the determinants associated with these IAPEs is needed to elicit preventive measures. Aim The primary aim of this study was to assess the prevalence of IAPEs. Secondary aims were to identify the type, severity, and determinan...
Article
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While the pharmacokinetics (PK) of morphine in children have been studied extensively, little is known about the pharmacodynamics (PD) of morphine in this population. Here, we quantified the concentration‐effect relationship of morphine for postoperative pain in preverbal children between 0 and 3 years of age. For this, we applied Item Response The...
Article
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For the management of iatrogenic withdrawal syndrome (IWS) in children, a quantitative understanding of the dynamics of IWS of commonly used opioids and sedatives is lacking. Here, we introduce a new mechanism-based pharmacokinetic-pharmacodynamic (PKPD) modeling approach for studying IWS in pediatric clinical datasets. One thousand seven hundred e...
Article
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Background Cardiorespiratory arrests are rare in paediatric intensive care units, yet intensive care nurses must be able to initiate resuscitation before medical assistance is available. For resuscitation to be successful, instant decision-making, team communication, and the coordinating role of the first responsible nurse are crucial. In-house res...
Article
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Background The Rotterdam Elderly Pain Observation Scale (REPOS) has not yet been validated for institutionalised cognitively impaired adults. To fill this gap of knowledge, we tested psychometric properties of the REPOS when used for pain assessment in this population. Methods In this multicentre observational study, residents were filmed during a...
Preprint
Full-text available
Background: Recipients of an organ transplantation face a number of challenges and often need to change their health behaviour. Good self-management skills are essential for optimal clinical outcomes. However, few interventions are available to support post-transplant self-management. To fill this gap, we developed a self-management support interve...
Article
Background: Morphine is commonly used for postoperative analgesia in children. Here we studied the pharmacodynamics of morphine in children after cardiac surgery receiving protocolized morphine. Methods: Data on morphine rescue requirements guided by validated pain scores in children (n = 35, 3-36 months) after cardiac surgery receiving morphine...
Article
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Purpose The quality of resuscitation and effective leadership are decisive for the outcome of a resuscitation. Nurses are usually the first responders upon cardiac arrest. Therefore, we started the “proficiency check” project, which aims to improve nurses' resuscitation and teamwork skills. This article describes the effectiveness of the proficienc...
Article
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DE CORONAPANDEMIE HEEFT ertoe geleid dat verpleegkundigen werken in onzekere en stressvolle omstandigheden. Goede ondersteuning van zorgprofessionals is belangrijk voor optimale vitaliteit en werkplezier. Er zijn verschillende initiatieven om verpleegkundigen te ondersteunen op de werkvloer, maar hierover is nog weinig kennisuitwisseling. Op basis...
Article
Objectives: To compare the pharmacokinetics and pharmacodynamics of IV midazolam after cardiac surgery between children with and without Down syndrome. Design: Prospective, single-center observational trial. Setting: PICU in a university-affiliated pediatric teaching hospital. Patients: Twenty-one children with Down syndrome and 17 without,...
Article
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Objectives Research specifically addressing implementation strategies regarding nursing guidelines is limited. The objective of this review was to provide an overview of strategies used to implement nursing guidelines in all nursing fields, as well as the effects of these strategies on patient-related nursing outcomes and guideline adherence. Ideal...
Article
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Aim To explore the perspectives of patients, their relatives and nurses on rooming-in for adult patients. Background The practice of having family stay overnight with an adult patient in hospital is quite new. To support rooming-in programs, the perspectives from all stakeholders should be taken into account. Methods All types of studies on roomi...
Article
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Background: In the last decade, there is an increasing focus on detecting and compiling lists of low-value nursing procedures. However, less is known about effective de-implementation strategies for these procedures. Therefore, the aim of this systematic review was to summarize the evidence of effective strategies to de-implement low-value nursing...
Article
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Titrating analgesic and sedative drugs in pediatric intensive care remains a challenge for caregivers due to the lack of pharmacodynamic knowledge in this population. The aim of the current study is to explore the concentration‐effect relationship for morphine‐associated oversedation after cardiac surgery in children aged 3 months to 3 years. Data...
Article
Background: Minimally invasive sampling methods are important to facilitate therapeutic drug monitoring (TDM) and pharmacokinetic research in children with behavioral problems. This study assessed the feasibility and pain of dried blood spot (DBS) sampling in this population. Methods: Repeated DBS sampling was performed in children with autism s...
Chapter
Dit hoofdstuk gaat over twee aspecten van leiderschap: rolontwikkeling als professional en persoonlijke ontwikkeling. Je rolontwikkeling betreft de activiteiten die je kunnen helpen om als leider te fungeren, niet alleen in je klinische microsysteem maar ook in de organisatorische en maatschappelijke context. We beschrijven verschillende modellen v...
Article
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Background: Research into the quality of care in psychiatry is scarce. Data collection is falling behind that for other fields of medicine and therefore the opportunity to improve care is missed. Aims: In this medical record study we aim to determine: (i) whether or not patients’ physical health indicators are assessed and pharmacological and behav...
Article
Objective: This study aims to determine if listening to music and watching cartoons are effective to distract children from pain and distress during procedures in the emergency room (ER). Methods: This study is a single-center, 3-armed, superiority randomized controlled trial comparing listening to music, watching cartoons, and standard care dur...
Article
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Spiritual care is recognized as a relevant dimension of health care. In the context of pediatric palliative end-of-life care, spirituality entails more than adhering to a spiritual worldview or religion. Interviews with parents whose critically ill child died in the pediatric intensive care unit revealed features of a spirituality that is fragmenta...
Article
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Item‐level data from composite scales can be analyzed with pharmacometric item response theory (IRT) models to improve the quantification of disease severity compared with the use of total composite scores. However, regular IRT models assume unidimensionality, which is violated in the scale measuring iatrogenic withdrawal in children because some i...
Article
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Objectives: Neonates born extremely prematurely are at high risk of acute and prolonged pain. Effective treatment requires reliable pain assessment, which is currently missing. Our study explores if existing pain assessment tools and physiological indicators measure pain and comfort accurately in this population. Methods: We prospectively collec...
Article
Background Prolonged treatment with analgesics and sedatives can result in iatrogenic withdrawal syndrome (IWS) in children being weaned from these drugs. ¹ Personalized weaning strategies might lower the incidence of IWS, but this requires a quantitative understanding of withdrawal over time in individual patients. Methods Data from 81 children (...
Article
Background Quantification of changes in disease states or clinical conditions is essential to establish drug effects and dosing guidelines. When single endpoints for direct measurements are lacking, multi-factorial observational scales may be used, like for instance pain or sedation scales. 1 2 Methods Analysis of data from multi-factorial observa...
Article
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Background: Critically ill children treated with invasive mechanical ventilation in a paediatric intensive care unit (PICU) may suffer from complications leading to prolonged duration of ventilation and PICU stay. Objective: The objective of this study is to find out if the use of a nurse-driven ventilation weaning protocol in a PICU can shorten...
Article
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Background: Pain in children and adolescents with cancer has been identified as an area where many healthcare professionals seek guidance. This protocol details a systematic review whose aim is to explore current knowledge regarding measurement instruments to assess pain (and pain-related distress) in children and adolescents with cancer. After co...
Article
Background: Premedication for neonatal intubation facilitates the procedure and reduces stress and physiological disturbances. However, no validated scoring system to assess the effect of premedication prior to intubation is available. Objective: To evaluate the usefulness of an Intubation Readiness Score (IRS) to assess the effect of premedicat...
Article
Background: Perioperative music interventions have been shown to reduce anxiety and pain in adults. This inexpensive, easily applicable intervention could be of benefit to children as well. Our objective was to determine the effects of music interventions on distress, anxiety, and postoperative pain in infants undergoing surgery. Methods: The Mu...
Article
Full-text available
Background The Rotterdam Elderly Pain Observation Scale (REPOS) has been proven useful to assess pain in non‐communicative and cognitively impaired nursing home residents. We evaluated whether the REPOS is also reliable and valid for pain assessment in the hospital setting. Methods In this prospective multicenter observational study, surgical pati...
Article
Full-text available
BACKGROUNDS: Reports of increasing incidence rates of delirium in critically ill children are reason for concern. We evaluated the measurement properties of the pediatric delirium component (PD-scale) of the Sophia Observation Withdrawal Symptoms scale Pediatric Delirium scale (SOS-PD scale). METHODS: In a multicenter prospective observational stud...
Article
Introduction: Pruritus or itch is a common symptom after burn injuries. The Itch Man Scale has been recommended to assess itch severity in children. The aim of this prospective observational study was to perform a cross-cultural validation of the Itch Man Scale by comparing it with the Numeric Rating Scale (NRS) and the Toronto Pediatric Itch Scal...
Article
The effectiveness of pain-reducing interventions in newborns can only be determined if pain measurement instruments are responsive; that is, able to detect a decrease in pain intensity after the pain-reducing intervention. This review assesses the methodologic quality of studies on this measurement property—the responsiveness. We searched the liter...
Article
Full-text available
Background Accurate measurement of preoperative anxiety is important for pediatric surgical patients’ care as well as for monitoring anxiety‐reducing interventions. The modified Yale Preoperative Anxiety Scale – short form is well validated for this purpose in children aged 2 years and above, but not in younger children. Aim We aimed to validate t...
Article
Full-text available
Background Morphine is worldwide the analgesic of first choice after cardiac surgery in children. Morphine has unwanted hemodynamic and respiratory side effects. Therefore, post–cardiac surgery patients may potentially benefit from a non-opioid drug for pain relief. A previous study has shown that intravenous (IV) paracetamol is effective and opioi...
Data
Appendix S1 Literature search Table S1 Study characteristics Table S2 Results of univariable meta‐regression analysis Table S3 Results of data driven multivariable meta‐regression analysis Fig. S1 Summary Risk of Bias Fig. S2 Funnel plot anxiety Fig. S3 Funnel plot pain Fig. S4 Summary forest plots meta‐analyses anxiety and meta‐analyses pai...
Article
Objectives: This study aimed to measure the effects of a newly developed follow-up programme on intensive care unit patient quality of care, as perceived by their relatives, and the appropriateness of the programme according to nurses. Methods and setting: This before and after implementation study was conducted in a level III intensive care uni...
Article
Background: Adequate analgesia and sedation is crucial in critical care. There is little knowledge on the extent of painful and stressful procedures on children admitted to a paediatric intensive care unit (PICU) and its analgesic and/or sedative management. Objective: The primary objective was to determine the number of painful and stressful pr...
Article
Full-text available
Background. Meningitis in children is a major health problem worldwide, leading to high rates of mortality and morbidity. Objectives. To describe the profile of patients treated for meningitis at a leading tertiary paediatric hospital (Red Cross War Memorial Children’s Hospital) in South Africa. Methods. This study describes all patients treated fo...
Article
Background: Postoperatively, young infants are admitted overnight in view of the risk for respiratory complications such as desaturation and apnea. This risk seems much lower than previously reported. Until what age this risk persists, and which infants might actually qualify for day-care treatment, is unknown. Methods: We retrospectively review...