Monique E Francois

Monique E Francois
University of Wollongong | UOW · Faculty of Science, Medicine and Health

PhD MPhEd BPhEd (Hons)

About

38
Publications
6,376
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598
Citations
Introduction
Monique E Francois is an NHMRC Investigator who currently works in the Faculty of Science, Medicine and Health at the University of Wollongong. Monique's research interests are in exercise and nutrition for pregnancy and gestational diabetes, and vascular health in type 2 diabetes. Areas include Exercise Physiology, Nutrition, Endocrinology and Metabolism.
Additional affiliations
February 2018 - present
University of Wollongong
Position
  • Lecturer
January 2017 - June 2017
University of British Columbia - Okanagan
Position
  • Instructor

Publications

Publications (38)
Article
Full-text available
Background: From late 2019, COVID-19 disease has infiltrated the global population causing widespread challenges to public health. One cohort that has received less attention, but who may be more vulnerable to the mental and physical health related impacts of COVID-19 restrictions are postpartum mothers. The aim of this study was to explore the men...
Chapter
Globally, diabetes of all types has reached epidemic levels, and the number of cases is expected to continue to rise as a result of unhealthful lifestyles, environmental factors, and genetics. The treatment of type 2 diabetes (the majority of cases) encompasses an individualized treatment plan that includes education, blood glucose management, card...
Article
Full-text available
Background: Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is considerable inter-individual variability in the V̇O2peak response to the same dose of exercise. Understanding how genetic factors c...
Article
Background & aims: Postprandial metabolic imbalances are important indicators of later developing cardiovascular disease (CVD). This study investigated the effects of food anthocyanins on vascular and microvascular function, and CVD associated biomarkers following a high fat high energy (HFHE) meal challenge in overweight older adults. Methods: Six...
Article
In type 2 diabetes, liver insulin resistance and excess hepatic glucose production results in elevated fasting glucose. A bedtime snack has been recommended to improve fasting glucose, yet there is little evidence supporting this recommendation. Moreover, the optimal composition of a bedtime snack is unknown. Purpose To determine whether a low-car...
Article
Full-text available
Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a...
Article
Background The breakfast meal often results in the largest postprandial hyperglycemic excursion in people with type 2 diabetes. Objective Our purpose was to investigate whether restricting carbohydrates at breakfast would be a simple and feasible strategy to reduce daily exposure to postprandial hyperglycemia. Design Adults with physician-diagnosed...
Article
The objective of this study was to test if a low-calorie diet plus interval exercise (LCD+INT) improves adiposopathy, an endocrine dysfunction, when compared with an energy-deficit-matched LCD in obese women. Subjects (age: 48.2 ± 2.4 years, body mass index: 37.8 ± 1.3 kg/m2) were randomized to a 13-day LCD (n = 12; mixed meals of ∼1200 kcal/day) o...
Article
Full-text available
There is heterogeneity in the observed O2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study was to combine data from different laboratories to compare O2peak trainability between various volumes of interval training and Moderate Intensity...
Article
Full-text available
Background/Objective Adventure racing is an ultra-endurance activity that imposes a unique multifaceted stress on the human body. The purpose of this field study was to examine the physiological responses to a 5-day adventure race. Methods Eight competitors, two teams (1 female each) in the 2012 GODZone adventure race volunteered. Competitors trek...
Article
Full-text available
The effect of work-matched exercise intensity on β-cell function is unknown in people with prediabetes prior to clinical weight loss. We determined if short-term moderate continuous (CONT) versus high intensity interval (INT) exercise increased β-cell function. Thirty-one subjects (Age: 61.4±2.5 yr; BMI: 32.1±1.0 kg/m2) with prediabetes (ADA criter...
Article
Full-text available
Although low-calorie diets (LCD) improve glucose regulation, it is unclear if interval exercise (INT) is additive. We examined the impact of an LCD versus LCD + INT training on ß-cell function in relation to glucose tolerance in obese adults. Twenty-six adults (Age: 46 ± 12 year; BMI 38 ± 6 kg/m²) were randomized to 2-week of LCD (~1200 kcal/day) o...
Article
Purpose: The optimal short-term exercise dose to improve glucose tolerance in relation to metabolic flexibility and/or insulin resistance is unknown. Therefore, we tested if short-term, work-matched continuous (CONT) versus interval (INT) exercise training improves glucose tolerance in part by reducing insulin resistance and increasing metabolic f...
Article
Aim The purpose of this study was to examine whether the combination of high-intensity interval training (HIIT) and post-exercise protein supplementation would improve cardiovascular outcomes in individuals with T2D. Methods In a double-blind controlled trial, fifty-three adults with T2D (free of CVD and not on exogenous insulin) were randomized...
Article
Postprandial hyperglycemia has deleterious effects on endothelial function. Restricting carbohydrate intake and postmeal walking have each been shown to reduce postprandial hyperglycemia, but their combination and subsequent effects on endothelial function have not been investigated. Here, we sought to examine the effect of blunting postprandial hy...
Article
Full-text available
Lifestyle interventions incorporating both diet and exercise strategies remain cornerstone therapies for treating metabolic disease. Carbohydrate-restriction and high-intensity interval training (HIIT) have independently been shown to improve cardiovascular and metabolic health. Carbohydrate-restriction reduces postprandial hyperglycemia, thereby l...
Article
Full-text available
Purpose: High-intensity interval training (HIIT) interventions improve cardiovascular health, yet the acute effects on circulating and functional biomarkers of cardiovascular function are unclear in individuals with type 2 diabetes (T2D). To explore this, we conducted two investigations to examine the acute response to HIIT in individuals with T2D...
Article
Full-text available
Background: High-intensity interval training (HIIT) can improve several aspects of cardiometabolic health. Previous studies have suggested that adaptations to exercise training can be augmented with post-exercise milk or protein consumption, but whether this nutritional strategy can impact the cardiometabolic adaptations to HIIT in type 2 diabetes...
Conference Paper
High-intensity interval training (HIIT) can improve several aspects of cardiometabolic health that are important for older adults with type 2 diabetes (T2D), including cardiorespiratory fitness, body composition and endothelial function. Previous studies have suggested that adaptations to exercise training can be augmented with post-exercise milk o...
Article
Full-text available
Purpose: To determine the impact of a single session of HIIT on cellular, molecular, and circulating markers of inflammation in individuals with T2D. Methods: Participants with T2D (n=10) and healthy age-matched controls (HC; n=9) completed an acute bout of HIIT (7 X 1-min @ ~85% maximal aerobic power output, separated by 1-min recovery) on a cy...
Article
Purpose: To compare energy use and substrate partitioning arising from repeated lower- versus upper-body sprints, or endurance exercise, across a 24-h period. Methods: Twelve untrained males (24±4 y) completed three trials in randomized order: (1) repeated sprints (five 30-s Wingate, 4.5-min recovery) on a cycle ergometer (SITLegs); (2) 50-min c...
Article
Different modes of exercise, disease and training status can modify endothelial shear stress and result in distinct effects on endothelial function. To date, no study has examined the influence of type 2 diabetes (T2D) and training status on the acute endothelial response to different modes of interval exercise (INT). We examined the effect of a si...
Article
Full-text available
Introduction: Exercise reduces arterial and central venous blood pressures during recovery, which contributes to its valuable anti-hypertensive effects and to facilitating hypervolemia. Repeated sprint exercise potently improves metabolic function, but its cardiovascular effects (esp. hematological) are less well-characterized, as are effects of e...
Article
Full-text available
IN BRIEF Recent research has shown that high-intensity interval training (HIIT) can promote improvements in glucose control and cardiovascular health in individuals with type 2 diabetes. This article summarizes the evidence and highlights the ways in which HIIT might be safely implemented as an adjunct to more traditional exercise approaches.
Article
Full-text available
High-intensity interval training (HIIT) has garnered attention in recent years as a time-efficient exercise option for improving cardiovascular and metabolic health. New research demonstrates that HIIT may be particularly effective for improving postprandial hyperglycemia in individuals with, or at risk for, type 2 diabetes (T2D). These findings ha...
Article
The aim of this study was to investigate whether small doses of intense exercise before each main meal ('exercise snacks') would result in better blood glucose control than a single bout of prolonged, continuous, moderate-intensity exercise in individuals with insulin resistance. Nine individuals completed three exercise interventions in randomised...

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Projects

Projects (6)
Archived project
Finding the impact COVID-19 restrictions had on women in the postpartum period
Project
Provide women with education to encourage changes in: - physical activity - mental health and wellbeing - diet quality - sleep